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Physiological 
Changes During 
Pregnancy 
Presented by :- 
Mansuri Asma
Weight gain 
 First 20weeks – 2.0kg 
 After 20weeks – 0.5kg per week 
 Total weight increase 12kg
Weight Gain – 10-12 kg 
 Fetus - 3.3kg 
 Uterus - 0.9kg 
 Placenta - 0.6kg 
 Liquor amni - 
0.8kg 
 Breast - 0.4kg 
 Increase in bld 
volume – 1.3kg 
 Increase in 
extracellular fluid 
– 1.2kg 
 Accumulation of 
fat & protein – 
3.5kg 
Reproductive 
weight gain 
Net maternal 
weight gain
Breast Changes
Skin changes 
Linea 
Nigra 
Straie 
Gravidarum
CHANGES OF THE 
CARDIOVASCULAR SYSTEM 
DURING PREGNANCY 
 Size of heart : increases about 12%. 
 Cardiac Capacity :- increases 70-80ml. 
 Cardiac Output :- increases by 30-40% 
till 30weeks 
increases15% till term
 White Blood Cells :- increases 
 Clotting Time :- 8minute
POSITION OF HEART :- 
 Due to elevation of diaphragm, the 
heart pushed upward & outward with 
slight rotation to left.
A. BLOOD VOLUME :- 
o Increases gradually by 30 to 50 
percent. 
o This results in decrease concentration 
of red blood cells and hemoglobin.
B. CARDIAC OUTPUT :- 
o Increases about 30 percent during the 
first and second trimester. 
o Change in output is reflected in the 
heart rate. It usually increases by 10 
beats per minute.
C. BLOOD PRESSURE. 
o Normally, the patient's blood pressure 
will not rise. 
 Systemic blood pressure declines 
slightly. 
 Diastolic blood pressure is reduced 5- 
10mm of Hg from
D. VENOUS RETURN. 
 The lower extremities are often 
hampered in the last months of 
pregnancy due to the expanding uterus 
restricting physical movement and 
interfering with the return of blood flow. 
 This results in swelling of the feet and 
legs.
CHANGES OF THE 
RESPIRATORY SYSTEM DURING 
PREGNANCY 
 Respiratory Rate : - Not alter 
 Amount of air exhaled per minute 
increases from 7 to11 litres. 
 Increased Vascularity :- Nasal 
Congetion. 
Nose bleed
CHANGES OF THE URINARY 
SYSTEM DURING PREGNANCY 
 Each Kidney :- Increases in length 1- 
1.5cm 
 Ureters :- Elongate, widen & curved 
Increase urinary stasis 
 Bladder : Increased Vascularity 
Decreased muscle tone 
Edamtous bladder Mucosa. 
Increased Frequency of Urine 
 G.F.R. :- Increases by 50%
CHANGES OF THE G.I. SYSTEM 
DURING PREGNANCY 
 Oral Cavity :- 
 increaesed Saliva & saliva become 
more acidic which promotes tooth 
decay. 
 Gums – more sensitive, swell easily & 
bleed. 
 Morning Sickness may present – 
characterised by vomiting & poor 
appetite. 
Heart burn may present
CHANGES IN ENDOCRINE 
SYSTEM 
 Placental Hormones :- 
 Human Chorionic 
Gonadotrophin(hCG) : secreted by 
syncytiotrophoblast. 
 It can be detected in maternal urine 
after 8-9days of fertilization. 
 It helps in maintaining the secretion of 
progesterone by the corpus luteum
Human placental lactogen 
(HPL) 
 Acts like growth hormone. 
 Important for increasing maternal blood 
free fatty acids, glucose & insulin 
concentration, increasing lipolysis
Maternal Endocrine glands 
 PITUITARY GLAND – enlarges & 
cause headache. 
 Secretion of FSH & LH inhibited. 
 Posterior lobe secrets Oxytocin & it 
increases in second stage of labour.
Thyroid gland 
 Enlarged & palpated. 
 Increased GFR. 
 Rise in BMR by 3rd month onwards. 
 Heart may beat faster causing 
palpitation. 
 PARATHYROID HORMONE increases 
throughout pregnancy.
ADRENAL GLAND 
 Slighlty enlarge. 
 Rise in ACTH, aldosterone, cortisol.
PANCREASE 
 Glucose level in blood may slightly 
decreased in early pregnancy. 
 In last half, level may increase.
Steroidal Hormone 
 Main hormones are – progesterone & 
oestrogen. 
 Progesterone & oestrogen level 
increase in early pregnancy. 
 These hormones stimulate growth of 
uterus. 
 They help in starting of the normal 
labour. 
 Also help in development of breasts 
during pregnancy.
CHANGES OF THE SKELETAL 
SYSTEM DURING PREGNANCY 
 There is alteration in the posture. 
 Later in pregnancy, it can lead to 
numbness, aching & weakness in arms. 
 Hormones in pregnancy such as 
progesterone , oestrogen & relaxin 
helps in relaxation of pelvic joints.
 Oestrogen makes pelvic joints movable 
 Progesterone relaxes & weaknes pelvic 
ligamnets. 
 Relaxin soften pelvic joints & ligaments.
Changes of pregnancy

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Changes of pregnancy

  • 1. Physiological Changes During Pregnancy Presented by :- Mansuri Asma
  • 2. Weight gain  First 20weeks – 2.0kg  After 20weeks – 0.5kg per week  Total weight increase 12kg
  • 3. Weight Gain – 10-12 kg  Fetus - 3.3kg  Uterus - 0.9kg  Placenta - 0.6kg  Liquor amni - 0.8kg  Breast - 0.4kg  Increase in bld volume – 1.3kg  Increase in extracellular fluid – 1.2kg  Accumulation of fat & protein – 3.5kg Reproductive weight gain Net maternal weight gain
  • 5. Skin changes Linea Nigra Straie Gravidarum
  • 6. CHANGES OF THE CARDIOVASCULAR SYSTEM DURING PREGNANCY  Size of heart : increases about 12%.  Cardiac Capacity :- increases 70-80ml.  Cardiac Output :- increases by 30-40% till 30weeks increases15% till term
  • 7.  White Blood Cells :- increases  Clotting Time :- 8minute
  • 8. POSITION OF HEART :-  Due to elevation of diaphragm, the heart pushed upward & outward with slight rotation to left.
  • 9. A. BLOOD VOLUME :- o Increases gradually by 30 to 50 percent. o This results in decrease concentration of red blood cells and hemoglobin.
  • 10. B. CARDIAC OUTPUT :- o Increases about 30 percent during the first and second trimester. o Change in output is reflected in the heart rate. It usually increases by 10 beats per minute.
  • 11. C. BLOOD PRESSURE. o Normally, the patient's blood pressure will not rise.  Systemic blood pressure declines slightly.  Diastolic blood pressure is reduced 5- 10mm of Hg from
  • 12. D. VENOUS RETURN.  The lower extremities are often hampered in the last months of pregnancy due to the expanding uterus restricting physical movement and interfering with the return of blood flow.  This results in swelling of the feet and legs.
  • 13. CHANGES OF THE RESPIRATORY SYSTEM DURING PREGNANCY  Respiratory Rate : - Not alter  Amount of air exhaled per minute increases from 7 to11 litres.  Increased Vascularity :- Nasal Congetion. Nose bleed
  • 14. CHANGES OF THE URINARY SYSTEM DURING PREGNANCY  Each Kidney :- Increases in length 1- 1.5cm  Ureters :- Elongate, widen & curved Increase urinary stasis  Bladder : Increased Vascularity Decreased muscle tone Edamtous bladder Mucosa. Increased Frequency of Urine  G.F.R. :- Increases by 50%
  • 15. CHANGES OF THE G.I. SYSTEM DURING PREGNANCY  Oral Cavity :-  increaesed Saliva & saliva become more acidic which promotes tooth decay.  Gums – more sensitive, swell easily & bleed.  Morning Sickness may present – characterised by vomiting & poor appetite. Heart burn may present
  • 16. CHANGES IN ENDOCRINE SYSTEM  Placental Hormones :-  Human Chorionic Gonadotrophin(hCG) : secreted by syncytiotrophoblast.  It can be detected in maternal urine after 8-9days of fertilization.  It helps in maintaining the secretion of progesterone by the corpus luteum
  • 17. Human placental lactogen (HPL)  Acts like growth hormone.  Important for increasing maternal blood free fatty acids, glucose & insulin concentration, increasing lipolysis
  • 18. Maternal Endocrine glands  PITUITARY GLAND – enlarges & cause headache.  Secretion of FSH & LH inhibited.  Posterior lobe secrets Oxytocin & it increases in second stage of labour.
  • 19. Thyroid gland  Enlarged & palpated.  Increased GFR.  Rise in BMR by 3rd month onwards.  Heart may beat faster causing palpitation.  PARATHYROID HORMONE increases throughout pregnancy.
  • 20. ADRENAL GLAND  Slighlty enlarge.  Rise in ACTH, aldosterone, cortisol.
  • 21. PANCREASE  Glucose level in blood may slightly decreased in early pregnancy.  In last half, level may increase.
  • 22. Steroidal Hormone  Main hormones are – progesterone & oestrogen.  Progesterone & oestrogen level increase in early pregnancy.  These hormones stimulate growth of uterus.  They help in starting of the normal labour.  Also help in development of breasts during pregnancy.
  • 23. CHANGES OF THE SKELETAL SYSTEM DURING PREGNANCY  There is alteration in the posture.  Later in pregnancy, it can lead to numbness, aching & weakness in arms.  Hormones in pregnancy such as progesterone , oestrogen & relaxin helps in relaxation of pelvic joints.
  • 24.  Oestrogen makes pelvic joints movable  Progesterone relaxes & weaknes pelvic ligamnets.  Relaxin soften pelvic joints & ligaments.