1. Seminar
Incorporation of
Unnatural Amino Acids
for the Expression of Proteins
with New Function
Ms. Jessica Torres
North Carolina
State University
at 10:40 Thursday Sept. 20
Refreshments at 10:30
Provided by Chemistry Circle
MMM 106
Living systems consist of a complex array of
components and proteins that are essential
biomacromolecules and are involved in all cellular
processes. Research has been directed towards the
study of biological processes in live cells by using
reporter tags. Tags allow for the detection of bio-
molecules such as proteins and/or their metabolites
as they move within different biological complexes.
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into proteins, both in vitro and in vivo, is a promis-
ing technology with tremendous potential to ad-
vance studies for basic biomedical research. The
technique allows incorporation of a vast diversity of
functional groups that extends beyond the conven-
tional mutagenesis of the 20 common amino acids. A
wide range of studies is enabled by using unnatural
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and spectroscopic probes, and functional groups for
bioconjugation reactions. The ability to apply the
technology into mammalian cells and model organ-
isms can provide insights into answering biomedical
questions relevant to human health.
These two alumni of the
summer program in 2012
will describe their research
experiences as part of the
seminar.