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1
Organism Diseases Reasons
S.aureus 1. Scaldede skin syndrome Exfoliatin
2. Toxic shock syndrome Toxic shock syndrome toxin
3. Food poisoning Enterotoxin
4. Skin infections like Boils, Abscess,
Furuncles, Carbuncles
5. Also can cause Pneumonia,
Osteoarthritis, endocarditis And
arthritis.
S.epidermidis Endocarditis
S.saprophyticus UTI in sexually active women.
S.pyogenes 1. Pharyngitis(S.Throat)
2. Pyogenic Skin Infections(Cellulitis
and others)
3. Toxinosis
a) Scarlet Fever
b) Streptococcal Toxic
shock syndrome.
4. Immunological Diseases
a) Rheumatic Fever
b) Acute Glumerulonephritis(AGN)
Erythrogenic Toxin
Pyrogenic toxin
Antibodies cross react with
antigen of heart, Joints, and
brain tissue.
Deposition of antigen-
antibody complex in
glomeruli.
S.agalactiae Neonatal meningitis and sepsis. Neonatal acquired
S.agalactiae during birth
from mother who carry it as
NF in Genital track.
S.pneumoniae 1. Pneumonia
2. Meningitis
Enterococci 1.UTI`s.
2.Can also cause endocarditis in
patients who have undergone
gastrointestinal or urinary track
surgery or instrumentation.
2
Organism Diseases Reasons
N.gonorrhoeae 1. Gonorrhea
2. If progress to fallopian
tube cause gonococcal
salphingitis and pelvic
inflammatory disease.
3. Opthalmia neonatorum(a
purulent conjunctivitis) and
this may lead to blindness.
N.meningitidis Meningitis Endotoxin called LOS is
resposible for tissue damage
in meningococcal disease.
B.anthracis 1.Cutaneous
anthrax( Malignant postule)
2. Pneumonic anthrax
3. Intestinal anthrax
4. Anthrax Meningitis
Direct contact of spore with
injured skin.
Inhalation of spore
containing dust.
Eating meat of infected
animals.
Complication of another
types of anthrax.
B.cereus Food poisoning of two
types
1. Emetic form or short
incubation.
2. Diarrheal form or long
incubation
Caused by heat stable
enterotoxin
Caused by heat labile
enterotoxin.
C.diphtheriae Diphtheria Diphtheria toxin
C.perfringens 1. Gas gangrene
2. Food poisioning
Enzymes and toxins called
lethal factors.
Enterotoxin.
C.tetani Tetanus Tetanospasmin
C.botulinum Botulism Botulism toxin
C.difficile Antibiotic- associated
pseudomembranous colitis
ExotoxinA & B.
Organism Diseases Reasons
3
Klebsilla 1. Pneumonia
2. UTI
3. Bacteremia
(Enterobacteriaciae mostly
cause nosocomial
infections)
Escherichia coli 1. UTI mostly in women.
2. Neonatal meningitis and
sepsis.
Capsule chemicallyvsimilar
to serogroup B
meningococci
Enterobacter May infect burns and
wounds and the respiratory
(causing pneumonia) and
urinary tracks.
Serratia Lower repiratory track and
urinary track infections.
Shigella 1. S.sonnei destroys mucosa
of large intestines but not
penetrate deeper.
2. S.dysenteriae cause
Shigellosis (Bacillary
dysentrey).
Shiga toxin that have
enterotoxic and cytotoxic
properties.
Salmonella Enteric / Typhoid fever.
Proteus 1. Nosocomal and
uncomplicated UTI.
2. Wound infections,
septesemias and
pneumonias in
compromised patients.
3. Struvite stones
Yersinia pestis 1. Bubonic (septicemic
plaque.
2. Pneumonic plaque
T.pallidum 1. Syphilis
2.Congenital syphilis Pregnant women transfer to
fetus causing death and
spontaneous abortion of
fetus.
H.influenzae 1. Bacterial meningitis
2. URTI
3. Pneumonia
V.cholera Cholera An enterotoxin called
cholera toxin.
4
Organism Diseases Reasons
C.jejuni 1. Acute Enteritis
2. Food Poisioning Invasive posioning
H.pylori Acute gastritis and may
cause gastric carcinoma
P.aeruginosa 1. Nosocomial Pneumonia
2. Nosocomial Infections of
Urinary track surgical
wounds and burns.
3. Localized infections in
Respiratory track.GIT, Eye,
Ear and may be
disseminated
4. Systemic infections
Bacteremia, bone and joint
infections Endocarditis,
Secondary Pneumonia and
skin infections.
B.pertusis Pertusis (Whooping cough) Toxins and virulence factors
causing death of ciliary cells

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Important table

  • 1. 1 Organism Diseases Reasons S.aureus 1. Scaldede skin syndrome Exfoliatin 2. Toxic shock syndrome Toxic shock syndrome toxin 3. Food poisoning Enterotoxin 4. Skin infections like Boils, Abscess, Furuncles, Carbuncles 5. Also can cause Pneumonia, Osteoarthritis, endocarditis And arthritis. S.epidermidis Endocarditis S.saprophyticus UTI in sexually active women. S.pyogenes 1. Pharyngitis(S.Throat) 2. Pyogenic Skin Infections(Cellulitis and others) 3. Toxinosis a) Scarlet Fever b) Streptococcal Toxic shock syndrome. 4. Immunological Diseases a) Rheumatic Fever b) Acute Glumerulonephritis(AGN) Erythrogenic Toxin Pyrogenic toxin Antibodies cross react with antigen of heart, Joints, and brain tissue. Deposition of antigen- antibody complex in glomeruli. S.agalactiae Neonatal meningitis and sepsis. Neonatal acquired S.agalactiae during birth from mother who carry it as NF in Genital track. S.pneumoniae 1. Pneumonia 2. Meningitis Enterococci 1.UTI`s. 2.Can also cause endocarditis in patients who have undergone gastrointestinal or urinary track surgery or instrumentation.
  • 2. 2 Organism Diseases Reasons N.gonorrhoeae 1. Gonorrhea 2. If progress to fallopian tube cause gonococcal salphingitis and pelvic inflammatory disease. 3. Opthalmia neonatorum(a purulent conjunctivitis) and this may lead to blindness. N.meningitidis Meningitis Endotoxin called LOS is resposible for tissue damage in meningococcal disease. B.anthracis 1.Cutaneous anthrax( Malignant postule) 2. Pneumonic anthrax 3. Intestinal anthrax 4. Anthrax Meningitis Direct contact of spore with injured skin. Inhalation of spore containing dust. Eating meat of infected animals. Complication of another types of anthrax. B.cereus Food poisoning of two types 1. Emetic form or short incubation. 2. Diarrheal form or long incubation Caused by heat stable enterotoxin Caused by heat labile enterotoxin. C.diphtheriae Diphtheria Diphtheria toxin C.perfringens 1. Gas gangrene 2. Food poisioning Enzymes and toxins called lethal factors. Enterotoxin. C.tetani Tetanus Tetanospasmin C.botulinum Botulism Botulism toxin C.difficile Antibiotic- associated pseudomembranous colitis ExotoxinA & B. Organism Diseases Reasons
  • 3. 3 Klebsilla 1. Pneumonia 2. UTI 3. Bacteremia (Enterobacteriaciae mostly cause nosocomial infections) Escherichia coli 1. UTI mostly in women. 2. Neonatal meningitis and sepsis. Capsule chemicallyvsimilar to serogroup B meningococci Enterobacter May infect burns and wounds and the respiratory (causing pneumonia) and urinary tracks. Serratia Lower repiratory track and urinary track infections. Shigella 1. S.sonnei destroys mucosa of large intestines but not penetrate deeper. 2. S.dysenteriae cause Shigellosis (Bacillary dysentrey). Shiga toxin that have enterotoxic and cytotoxic properties. Salmonella Enteric / Typhoid fever. Proteus 1. Nosocomal and uncomplicated UTI. 2. Wound infections, septesemias and pneumonias in compromised patients. 3. Struvite stones Yersinia pestis 1. Bubonic (septicemic plaque. 2. Pneumonic plaque T.pallidum 1. Syphilis 2.Congenital syphilis Pregnant women transfer to fetus causing death and spontaneous abortion of fetus. H.influenzae 1. Bacterial meningitis 2. URTI 3. Pneumonia V.cholera Cholera An enterotoxin called cholera toxin.
  • 4. 4 Organism Diseases Reasons C.jejuni 1. Acute Enteritis 2. Food Poisioning Invasive posioning H.pylori Acute gastritis and may cause gastric carcinoma P.aeruginosa 1. Nosocomial Pneumonia 2. Nosocomial Infections of Urinary track surgical wounds and burns. 3. Localized infections in Respiratory track.GIT, Eye, Ear and may be disseminated 4. Systemic infections Bacteremia, bone and joint infections Endocarditis, Secondary Pneumonia and skin infections. B.pertusis Pertusis (Whooping cough) Toxins and virulence factors causing death of ciliary cells