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WDC's Global Vision on Dementia Cure by 2025
1. The World Dementia Council’s
Global Vision on Dementia
Jeremy Hughes CBE
UK Member, World Dementia Council
Alzheimer Scotland Conference
June 2016
2. • Dementia is one of the most challenging public
health challenges
• The European Union countries are at the forefront
of the aging of the population –
the primary risk factor for the diseases causing
dementia
• There is a global collaboration and synergy
between:
– WHO – bringing together Member States and
supporting the Global Dementia Observatory
– The World Dementia Council - providing a
complementary role of bringing together individuals
from all stakeholders groups in order to support,
amplify and coordinate a global response
The Global Dementia Challenge
3. • In Dec 2013, UK hosted a G8
Dementia Summit
• Goal was to bring together experts
across the world to start a global
conversation about solutions for
dementia
• The Summit resulted in a
declaration that set out an
international response to dementia
with the aim of identifying a cure or
a disease modifying therapy by
2025
The World Dementia Council
"If we are to beat dementia, we must also work
globally, with nations, business and scientists from all
over the world working together as we did with cancer,
and with HIV and AIDS. This is going to be a bigger and
bigger issue; the key is to keep pushing.”
David Cameron, December 11, 2013 (BBC News)
4. • In February 2014, the UK Prime Minister appointed Dr Dennis
Gillings as the World Dementia Envoy & he established the
World Dementia Council (WDC)
• The WDC consists of a wide range of experts from research,
academia, industry, the NGO sector, people living with
dementia & governments
The World Dementia Council
World Dementia Council Full Members, February 2016
5. • Following the WHO First Ministerial conference a
broad consensus was reached amongst key global
stakeholders & the WDC, on a global model to
pursue with the challenge of dementia
• A truly complementarity approach:
Establishment of the WHO Global Dementia
Observatory
Global Teams from the WDC that are
independent of governments & any one
organisation or sector
No formal governance between these two
pillars but a collaborative approach to optimize
global impact
G7 to Global – The Continuity Model
6. • The World Dementia Council re-formed and
reconstituted to include a more global membership
• February 2016, in line with this independence
– new members drawn from a range of sectors &
organisations across the wider dementia community
– the WDC Chair – Yves Joanette & Vice Chair – Raj
Long were appointed by its members
• UK Model Evolution
– From a single Envoy/WDC Chair role by Dr Dennis
Gillings to a UK Dementia Envoy distinct from WDC
Chair
– Current UK Dementia Envoy is David Mayhew
The Re-formed World Dementia Council
7. 1. Innovative and global finance models
2. Integrated drug development
3. Open science collaborative global research
including the use of big data
4. Ensuring adequate care for people living with
dementia and their carers in high, middle and
low-income countries
5. Facilitating the identification and the
dissemination of risk reduction strategies
Integrating cross-cutting themes
Women and dementia
Awareness
Stigma
Inequalities
Priorities for the Council’s Actions
8. In March 2015, the WDC helped to shape the UK-led work
to establish the Dementia Discovery Fund – a ground
breaking public/private venture capital fund which aims to
finance pre-clinical research to find new drugs to treat
dementia. The initial fund is just over $100M & it aims to
raise a further $100M during 2016
8
Example – Finance Models
9. • In Nov 2014, Raj Long convened 11 regulators from 10
jurisdictions to work collaboratively on dementia & they
have collectively identified 5 work streams
• In July 2015, an independent report was published on
the dementia drug development pathway ‘Finding the
path for a cure for dementia setting out key actions
for change which the international community needs to
implement to improve & speed up the dementia drug
pathway.
Example – Integrated Drug Development
10.
11. • The WDC has provided input into & helped shape a
number of international collaborative projects that
are attempting to enable greater & more effective
data sharing. Examples include:
• ‘The development of good practices on data
governance’ resulting in a report from the OECD
& Oxford Internet Institute published in March
2015
• The Canadian Consortium of Neurodegeneration
in Ageing (CCNA) & the Dementia Platform UK
(DPUK) collaboration to create an integrated
system to share & analyse large scale & complex
cohort based datasets
Example – Research,
Open Science and Big Data
12. • The WDC worked closely with OECD & WHO on a
framework to help address the needs of people with
dementia & their carers, covering prevention,
diagnosis, post diagnosis care & support
• The framework was included in the OECD report
“Addressing Dementia: the OECD response”
Example – Care
13. • The World Dementia Council is now ready to
move forward with all the Member States of WHO
• Five Global Teams made up of Council Members
and other experts will facilitate moving forward on
all five priorities and cross-cutting themes
• With the WHO and the Member states, innovative
actions will be advocated, and supported
• The European Union will be an important ally in
order to ensure that fewer individuals live with
dementia, and that those living with dementia are
living well
The World Dementia Council
Moving Forward