Phosphorylation is an example of regulation of enzyme activity by covalent modification. a. Enzymes are phosphorylated on amino acids. Which amino acids can be phosphorylated? b. What is required for an amino acid to become phosphorylated? Show an example chemical reaction. c. What is required for an amino acid to become dephosphorylated? Show an example chemical reaction. d. What controls whether a population of amino acid residues are phosphorylated or dephosphorylated? e. In what way is this process of phosphorylation/dephosphorylation hormone dependent?.