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Anna who produces eggs and Syed who produces sperm have.pdf

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A couple, Anna and Syed, had a child with Down syndrome caused by an extra copy of chromosome 21. A genetic test was run on the child to determine if the extra chromosome came from Anna or Syed. The test results show that lane B best fits the child's genotype, indicating that the nondisjunction event occurred in Anna during meiosis I, giving the child an extra chromosome 21 from her.

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Anna (who produces eggs) and Syed (who produces sperm), have a child with Downs syndrome that results from trisomy of chromosome 21. Using a microsatellite sequence on chromosome 21, you run a gel. Darker bands indicate signals of twice the intensity. If a nondisjunction event occurred in Anna during meiosis I, which lane (A, B, C, D) best fits the genotype of their child? Explain your choice, clearly identifying why that lane is correct and why the other lanes are incorrect. Assume no recombination.

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Anna who produces eggs and Syed who produces sperm have.pdf

  • 1. Anna (who produces eggs) and Syed (who produces sperm), have a child with Downs syndrome that results from trisomy of chromosome 21. Using a microsatellite sequence on chromosome 21, you run a gel. Darker bands indicate signals of twice the intensity. If a nondisjunction event occurred in Anna during meiosis I, which lane (A, B, C, D) best fits the genotype of their child? Explain your choice, clearly identifying why that lane is correct and why the other lanes are incorrect. Assume no recombination.