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Dr. Abhishek Tiwari,
Assistant Professor,
Department of Community Medicine,
Moti Lal Nehru Medical College, Prayagraj
Epidemiology,
Prevention &
Control of
Hypertension
Learning Objectives
To understand why Hypertension is a Public
Health Concern
To understand the Epidemiology of Hypertension
What all should be done to Prevent it ?
Methods available to Control Hypertension ?
11-10-2021
2
Introduction
Hypertension
or elevated blood
pressure - is a
serious medical
condition that
significantly
increases the risks
of heart, brain,
kidney and other
diseases.
11-10-2021
3
Introduction
An estimated 1.13 billion people worldwide have
HYPERTENSION, most of them (2/3rd) living in low &
middle-income countries.
Prevalence 30-40%, 24% in men & 20% women
Prevalence > 60% in people aged >60 years
In 2015, 1 in 4 men & 1 in 5 women had HTN
Annual increase of 15-20% estimated by 2025
A major cause of premature death worldwide.
One of the global targets for Noncommunicable
diseases is to reduce the prevalence of hypertension by
25% by 2025 (baseline 2010)
Burden - India
National Family Health Survey 2015-16
11% women and 15% in men were hypertensive
Prevalence was found to be higher in males and
those with high Body Mass Index.
Consistent increase in prevalence with increase in
BMI
Now – health & wellness center are focusing on
Noncommunicable Diseases and their prevention in
particular
Hypertension
Blood pressure is the force exerted by circulating blood
against the walls of the body’s arteries, the major blood
vessels in the body. Hypertension is when blood
pressure is too high.
The first (systolic) number represents the pressure in
blood vessels when the heart contracts or beats. The
second (diastolic) number represents the pressure in
the vessels when the heart rests between beats.
If on 2 different days, systolic BP readings on both
days is ≥140 mmHg and/or the diastolic BP readings on
both days is ≥90 mmHg only then we diagnose as HTN
Symptoms of HTN
Hypertension is called a "silent killer“
Most people with HTN are unaware of their status as
they have no warning signs or symptoms
It is essential to get blood pressure measured regularly.
When symptoms do occur, they are early morning
headaches, nosebleeds, irregular heart rhythms, vision
changes & buzzing in the ears
Severe hypertension can cause fatigue, nausea,
vomiting, confusion, anxiety, chest pain & muscle
tremors.
The only way to detect hypertension is to measure
Grading of HTN
Category Systolic (mm of
Hg)
Diastolic (mm
of Hg)
Optimal <120 And < 80
Normal 120 – 129 And/or 80 - 84
High Normal 130 – 139 And/or 85 - 89
Grade 1 HTN 140 – 159 And/or 90 - 99
Grade 2 HTN 160 – 179 And/or 100 - 109
Grade 3 HTN >= 180 And/or > 110
Isolated systolic HTN >= 140 And < 90
When systolic BP & diastolic BP readings fall in different
category, the higher category should be taken.
Higher the BP higher the risk of Cardiovascular disease.
Extent of organ damage varies in individuals with HTN, hence
it depends on many factors.
Measurement
Accurate measurement are essential under
STANDARDIZED conditions for valid comparisons
3 identified source of errors
a) Observer Error – Hearing acuity, interpretation of
korotkow sounds.
b) Instrumental error – e.g. leaking valves, cuffs not
encircling arm etc.
c) Subject errors – physical environment, position,
external stimuli such as fear, anxiety & so on
Sitting position is recommended and a uniform policy
of measurement is essential
Classification
Primary [Essential]
Cause unknown, accounts for 90% cases, most
common
Secondary
Some other disease process or abnormality
involved in causation, like kidney disease, adrenal
gland disorder, narrowing of Aorta, toxemia of
pregnancy, altogether less than 10% cases
Risk Factors of HTN
The “LIFESTYLE” disease has a range of risk factors
HTN is itself a major risk factor and it has its own risk
factors
NON MODIFIABLE
1) Age – BP increases with age in both sexes due to
accumulation of environmental factors and ageing
phenomenon
2) Sex – in adolescence Men display higher average,
difference is clearly evident in young & adults. Later
on this pattern narrows & may even reverse. Post
menopausal changes are contributory.
.
Risk Factors of HTN
NON MODIFIABLE
3) Genetic factors – evidence suggests BP levels are
determined partly by genetic factors, with
polygenic inheritance.
Twin studies - BP of monozygotic twins are strongly
related than zygotic twins. In contrast no relation
was found in levels of husband & wife, and between
adopted children.
Family studies – children of 2 normotensive parents
have 3% possibility of developing HTN, while it is
45% for hypertensive parents
.
Risk Factors of HTN
NON MODIFIABLE
4) Ethnicity – Population studies have shown higher
levels in black population
MODIFIABLE
1. OBESITY – Greater the wt. gain greater the risk.
On loosing weight the BP also decreases. “Central
obesity” has been positively correlated with high
BP
2. SALT INTAKE – high intake 7-8 g/day increases
the risk. Low sodium intake decreases the BP.
Japan sodium intake is above 400 mmol/day has
higher incidence
.
Risk Factors of HTN
3) SATURATED FAT – It raises BP & serum
cholesterol. Cholesterol & LDL are involved in
atherosclerosis.
Recommended – greater intake of PUFA and less
intake of saturated fat. Fat intake should be less than
30% of total calories.
4) DIETARY FIBRE – beneficial in reducing total
plasma total & LDL cholesterol.
5) ALCOHOL INTAKE – high intake is harmful
.
Risk Factors of HTN
6) HEART RATE – hypertensive subjects were found
to have higher heart rate. This may be due to
resetting of sympathetic activity at a higher level
7) PHYSICAL INACTIVITY – minimum of 30 minutes
for at least 5 days a week is essential to reduce
the risk of HTN and NCD. Sedentary lifestyle leads
to obesity and predisposes to NCD
8) ENVIRONMENTAL STRESS – higher noradrenaline
in hypertensive supports that over activity of
sympathetic system is involved
.
Risk Factors of HTN
9) SOCIO-ECONOMIC STATUS – earlier higher
disease burden in developed countries, but now
the trend is transitioning. More cases in low &
middle income countries.
10)OTHER FACTORS – most common cause of
secondary HTN is oral contraception, because of
oestrogen
.
Rule of Halves
Hypertension is an
“ICEBERG” Disease
Only 1/2 have been
diagnosed
Only 1/2 of those
diagnosed have been
treated
Only 1/2 of those
treated are adequately
controlled
Thus, only
12.5%overall are
adequately controlled
Tracking of Blood Pressure
If blood pressure of
individuals were followed up
over a period of years from
early childhood into adult
life, then those whose
pressures were initially high
in distribution, would
continue in the same “track”
as adults.
This phenomenon of
PERSISTENCE is called
tracking & can be applied in
identifying “AT RISK”
children & adolescents.
Causes of HTN
A
Prevention
WHO recommended approach:
1. Primary Prevention- “all measures to reduce the
incidence of disease in population by reducing
RISK of onset”
a. Population Strategy
b. High Risk Strategy
2. Secondary Prevention
We can control hypertension by medication
(secondary) but the ultimate goal is PRIMARY
Prevention 11-10-2021
20
Population Strategy- for All
Even a small reduction in average BP of Population
would produce large reduction in incidence of CVD
complications.
GOAL – to shift the BP
towards lower levels
with multifactorial
approach & non
Pharmacotherapeutic
interventions
11-10-2021
21
Interventions
Nutrition – DASH (dietary
approach to stop HTN), low
sodium & fat
Weight reduction – maintain
BMI < 25
Exercise promotion
Behavioural changes
Health Education
Self Care
High - Risk Strategy
GOAL – To prevent the attainment of levels of
blood pressure which requires treatment.
Appropriate for community with low prevalence of
risk factors
Detection of High RISK subjects by assessing all
predisposing factors & clinical methods
11-10-2021
22
Interventions to identify those at Higher RISK
Tracking of Blood Pressure from childhood
Family History details of hypertension
Secondary Prevention
GOAL – To detect & control high BP of effected
individual
1) Early Case detection – major problem, remember
silent killer and iceberg phenomenon. SCREENING
of population with adequate follow up
2) Treatment - modern Anti-hypertensive therapy
3) Patient compliance – “the extent to which the
patients behaviour coincides with clinical
prescription” . Health education improves
compliance
it’s a control and not cure so has to be LIFELONG
11-10-2021
23
Treatment
India
Hypertension
Management
Initiative (in
collaboration
with ICMR)
Measure BP of
all above 30
years
If SBP >= 140
and/or DBP >=
90 mm of Hg
then follow.
11-10-2021
24
Newer initiatives for NCD
Screening at all levels in the health care delivery
system from sub-centre & above
 Capacity building at various levels of health care for
prevention, early diagnosis, treatment, rehabilitation,
IEC/BCC, operational research and rehabilitation.
To support for development of database of NCDs
through Surveillance System and to monitor NCD
morbidity and mortality and risk factors.
Health promotion through behaviour change with
involvement of community, civil society, community
based organizations, media etc.
11-10-2021
25
Thank you all
11-10-2021
26

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Epidemiology, Prevention & Control of Hypertension

  • 1. Dr. Abhishek Tiwari, Assistant Professor, Department of Community Medicine, Moti Lal Nehru Medical College, Prayagraj Epidemiology, Prevention & Control of Hypertension
  • 2. Learning Objectives To understand why Hypertension is a Public Health Concern To understand the Epidemiology of Hypertension What all should be done to Prevent it ? Methods available to Control Hypertension ? 11-10-2021 2
  • 3. Introduction Hypertension or elevated blood pressure - is a serious medical condition that significantly increases the risks of heart, brain, kidney and other diseases. 11-10-2021 3
  • 4. Introduction An estimated 1.13 billion people worldwide have HYPERTENSION, most of them (2/3rd) living in low & middle-income countries. Prevalence 30-40%, 24% in men & 20% women Prevalence > 60% in people aged >60 years In 2015, 1 in 4 men & 1 in 5 women had HTN Annual increase of 15-20% estimated by 2025 A major cause of premature death worldwide. One of the global targets for Noncommunicable diseases is to reduce the prevalence of hypertension by 25% by 2025 (baseline 2010)
  • 5. Burden - India National Family Health Survey 2015-16 11% women and 15% in men were hypertensive Prevalence was found to be higher in males and those with high Body Mass Index. Consistent increase in prevalence with increase in BMI Now – health & wellness center are focusing on Noncommunicable Diseases and their prevention in particular
  • 6. Hypertension Blood pressure is the force exerted by circulating blood against the walls of the body’s arteries, the major blood vessels in the body. Hypertension is when blood pressure is too high. The first (systolic) number represents the pressure in blood vessels when the heart contracts or beats. The second (diastolic) number represents the pressure in the vessels when the heart rests between beats. If on 2 different days, systolic BP readings on both days is ≥140 mmHg and/or the diastolic BP readings on both days is ≥90 mmHg only then we diagnose as HTN
  • 7. Symptoms of HTN Hypertension is called a "silent killer“ Most people with HTN are unaware of their status as they have no warning signs or symptoms It is essential to get blood pressure measured regularly. When symptoms do occur, they are early morning headaches, nosebleeds, irregular heart rhythms, vision changes & buzzing in the ears Severe hypertension can cause fatigue, nausea, vomiting, confusion, anxiety, chest pain & muscle tremors. The only way to detect hypertension is to measure
  • 8. Grading of HTN Category Systolic (mm of Hg) Diastolic (mm of Hg) Optimal <120 And < 80 Normal 120 – 129 And/or 80 - 84 High Normal 130 – 139 And/or 85 - 89 Grade 1 HTN 140 – 159 And/or 90 - 99 Grade 2 HTN 160 – 179 And/or 100 - 109 Grade 3 HTN >= 180 And/or > 110 Isolated systolic HTN >= 140 And < 90 When systolic BP & diastolic BP readings fall in different category, the higher category should be taken. Higher the BP higher the risk of Cardiovascular disease. Extent of organ damage varies in individuals with HTN, hence it depends on many factors.
  • 9. Measurement Accurate measurement are essential under STANDARDIZED conditions for valid comparisons 3 identified source of errors a) Observer Error – Hearing acuity, interpretation of korotkow sounds. b) Instrumental error – e.g. leaking valves, cuffs not encircling arm etc. c) Subject errors – physical environment, position, external stimuli such as fear, anxiety & so on Sitting position is recommended and a uniform policy of measurement is essential
  • 10. Classification Primary [Essential] Cause unknown, accounts for 90% cases, most common Secondary Some other disease process or abnormality involved in causation, like kidney disease, adrenal gland disorder, narrowing of Aorta, toxemia of pregnancy, altogether less than 10% cases
  • 11. Risk Factors of HTN The “LIFESTYLE” disease has a range of risk factors HTN is itself a major risk factor and it has its own risk factors NON MODIFIABLE 1) Age – BP increases with age in both sexes due to accumulation of environmental factors and ageing phenomenon 2) Sex – in adolescence Men display higher average, difference is clearly evident in young & adults. Later on this pattern narrows & may even reverse. Post menopausal changes are contributory. .
  • 12. Risk Factors of HTN NON MODIFIABLE 3) Genetic factors – evidence suggests BP levels are determined partly by genetic factors, with polygenic inheritance. Twin studies - BP of monozygotic twins are strongly related than zygotic twins. In contrast no relation was found in levels of husband & wife, and between adopted children. Family studies – children of 2 normotensive parents have 3% possibility of developing HTN, while it is 45% for hypertensive parents .
  • 13. Risk Factors of HTN NON MODIFIABLE 4) Ethnicity – Population studies have shown higher levels in black population MODIFIABLE 1. OBESITY – Greater the wt. gain greater the risk. On loosing weight the BP also decreases. “Central obesity” has been positively correlated with high BP 2. SALT INTAKE – high intake 7-8 g/day increases the risk. Low sodium intake decreases the BP. Japan sodium intake is above 400 mmol/day has higher incidence .
  • 14. Risk Factors of HTN 3) SATURATED FAT – It raises BP & serum cholesterol. Cholesterol & LDL are involved in atherosclerosis. Recommended – greater intake of PUFA and less intake of saturated fat. Fat intake should be less than 30% of total calories. 4) DIETARY FIBRE – beneficial in reducing total plasma total & LDL cholesterol. 5) ALCOHOL INTAKE – high intake is harmful .
  • 15. Risk Factors of HTN 6) HEART RATE – hypertensive subjects were found to have higher heart rate. This may be due to resetting of sympathetic activity at a higher level 7) PHYSICAL INACTIVITY – minimum of 30 minutes for at least 5 days a week is essential to reduce the risk of HTN and NCD. Sedentary lifestyle leads to obesity and predisposes to NCD 8) ENVIRONMENTAL STRESS – higher noradrenaline in hypertensive supports that over activity of sympathetic system is involved .
  • 16. Risk Factors of HTN 9) SOCIO-ECONOMIC STATUS – earlier higher disease burden in developed countries, but now the trend is transitioning. More cases in low & middle income countries. 10)OTHER FACTORS – most common cause of secondary HTN is oral contraception, because of oestrogen .
  • 17. Rule of Halves Hypertension is an “ICEBERG” Disease Only 1/2 have been diagnosed Only 1/2 of those diagnosed have been treated Only 1/2 of those treated are adequately controlled Thus, only 12.5%overall are adequately controlled
  • 18. Tracking of Blood Pressure If blood pressure of individuals were followed up over a period of years from early childhood into adult life, then those whose pressures were initially high in distribution, would continue in the same “track” as adults. This phenomenon of PERSISTENCE is called tracking & can be applied in identifying “AT RISK” children & adolescents.
  • 20. Prevention WHO recommended approach: 1. Primary Prevention- “all measures to reduce the incidence of disease in population by reducing RISK of onset” a. Population Strategy b. High Risk Strategy 2. Secondary Prevention We can control hypertension by medication (secondary) but the ultimate goal is PRIMARY Prevention 11-10-2021 20
  • 21. Population Strategy- for All Even a small reduction in average BP of Population would produce large reduction in incidence of CVD complications. GOAL – to shift the BP towards lower levels with multifactorial approach & non Pharmacotherapeutic interventions 11-10-2021 21 Interventions Nutrition – DASH (dietary approach to stop HTN), low sodium & fat Weight reduction – maintain BMI < 25 Exercise promotion Behavioural changes Health Education Self Care
  • 22. High - Risk Strategy GOAL – To prevent the attainment of levels of blood pressure which requires treatment. Appropriate for community with low prevalence of risk factors Detection of High RISK subjects by assessing all predisposing factors & clinical methods 11-10-2021 22 Interventions to identify those at Higher RISK Tracking of Blood Pressure from childhood Family History details of hypertension
  • 23. Secondary Prevention GOAL – To detect & control high BP of effected individual 1) Early Case detection – major problem, remember silent killer and iceberg phenomenon. SCREENING of population with adequate follow up 2) Treatment - modern Anti-hypertensive therapy 3) Patient compliance – “the extent to which the patients behaviour coincides with clinical prescription” . Health education improves compliance it’s a control and not cure so has to be LIFELONG 11-10-2021 23
  • 24. Treatment India Hypertension Management Initiative (in collaboration with ICMR) Measure BP of all above 30 years If SBP >= 140 and/or DBP >= 90 mm of Hg then follow. 11-10-2021 24
  • 25. Newer initiatives for NCD Screening at all levels in the health care delivery system from sub-centre & above  Capacity building at various levels of health care for prevention, early diagnosis, treatment, rehabilitation, IEC/BCC, operational research and rehabilitation. To support for development of database of NCDs through Surveillance System and to monitor NCD morbidity and mortality and risk factors. Health promotion through behaviour change with involvement of community, civil society, community based organizations, media etc. 11-10-2021 25