EECS 441 W18 Company Report _yuweibao

1. YUWEI BAO(YUWEIBAO)

2. PROBLEM?
• Analysis/Sequence
• Any Living Thing
• By Any Person
• In Any Environment

3. PRODUCTS
PROMETHION
Up to 48 flow cells
GRIDION
5 flow cells
MINION
1 flow cell
SMIDGION
1 flow cell

4. Prepare Sequence Analysis
HOW IT WORKS

5. FINANCIAL INFO
7.75
10
14
17.4
25
31.4
40
35
70
100 100
0
20
40
60
80
100
120
2006 2008 2009 2010 2011 2012 2013 2014 2015 2016 2018
Funding Rounds (Million Pounds)
0
1,000,000
2,000,000
3,000,000
4,000,000
5,000,000
6,000,000
7,000,000
2011 2012 2013 2014 2015 2016
Operating Revenue(USD)
0
50,000,000
100,000,000
150,000,000
200,000,000
250,000,000
2011 2012 2013 2014 2015 2016
Total Assets(USD)

6. BUSINESS MODEL
Next Gen Sequencing
Products
Device
>$1,000
Flow cells
>$900
Kits
~$600
Community Service
Analysis
$0
Training
~$15,000
Support
$1000/mo

7. HISTORY
2005: Founded
• Dr. Gordon Sanghera
• Dr. Spike Wilcocks
• Prof. Hagan Bayley
2008: Executive team
• Dr. John Milton
• Clive G. Brown
2012: first data
published
2014: MinION early trial
2015: commercially available
2016: patent battle
w/ Illumina settled
2017: support RNA sequencing

8. SECRET SAUCE
• The PORE!!!
• Portable
• Real-time
• Long-read
• Low cost
• Strong Executive Team
• Environment

9. COMPETITION
Oxford Nanopore Illumina
Length 1~2 kbp ~100 bp
Time/run Real time 1~2 days
Accuracy …homopolymers… …sequence assembly…
Portability YES NO
Cost/Mb $0.025 $0.07

10. PREDICTION
• SUCCESS!!!!
• Funding
• Efficient team
• Next gen technique
• & precision health

11. REFERENCE
• https://nanoporetech.com/
• https://www.bloomberg.com/research/stocks/private/snapshot.asp?privcapId=22510293
• http://homolog.us/blogs/blog/2016/12/16/oxford-nanopore/
• https://orbis-bvdinfo-com.proxy.lib.umich.edu/version-201843/Report.serv?_CID=98&context=3LMTF8VTTD11RK0&SeqNr=0
• https://www.illumina.com/
• https://en.wikipedia.org/wiki/DNA_sequencer
• http://www.opiniomics.org/which-sequencer-should-you-buy/
• http://nextgenseek.com/2012/08/comparing-price-and-tech-specs-of-illumina-miseq-ion-torrent-pgm-454-gs-junior-and-pacbio-rs/
• https://nanoporetech.com/about-us/news/human-genome-minion

12. 4/9/18SAMPLE FOOTER TEXT 12