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From Technologies to Markets
@2019
Medical Wearables:
Market and Technology
Trends 2019
Sample
2
TABLE OF CONTENTS
• Executive summary 08
• Context 28
• Definition of medical wearables
• A little beat of History
• What’s new?
• Product launch, collaboration and fundraising
• Market forecasts 53
• Global market data and Market forecasts
• Market data and forecasts 2017-2024 in $M by segment
• Market forecasts by sensor types
• Market shares
• Market trends 69
• Market drivers, challenges
• R&D Development time and investments related
• Market segmentation and segment description
• Technology requirement/ application
• Key players/ segment
• Top Medical Devices: how they position themselves?
• Technology trends 132
• Technology description of sensors for medical wearables
• Sensors
• Manufacturing process and material
• Roadmaps
• Overview on emerging flexible, Stretchable, printed, and hybrid
electronics for medical applications.
• Supply chain 185
• Ecosystems
• Business models and player’s strategy
• Supply chain analysis
• Regulation, reimbursement aspects
• Market access
• Technical challenges of fabrication, packaging, and assembly
technics
• Conclusion 233
• Perspectives
• What’s next
Medical Wearables: Market & Technology Analysis 2019 | Sample | www.yole.fr | ©2019
3
Biography & contact
ABOUT THE AUTHORS
Asma Siari
As a Technology & Market Analyst, Biotechnologies & Molecular Innovations, Medical Technologies in the Life Sciences & Healthcare division at Yole
Développement (Yole), Asma Siari is involved in the development of technology & market reports as well as the production of custom consulting projects. After a
Master’s degree in Biotechnologies, Diagnostic Therapeutics & Management, Asma served as Research Assistant at the Moores Cancer Center (San Diego, CA).
She is a coauthor in three scientific publications published in the Molecular Cancer Research Journal. Asma Siari is graduated with an Advanced Master’s degree in
International Strategy & Marketing BtoB from EM Lyon Business School (France).
Email: siari@yole.fr
Jérôme Mouly
Jerôme Mouly serves as a Senior Technology & Market Analyst & Business Developer specialized in microtechnologies for inkjet & bioMEMS sensors.
Since 2000, he has participated in more than 100 marketing and technological analyses for industrial groups, start-ups and institutes. Previously, Jerome
was involved in a support action for value creation of smart miniaturized systems research projects at Yole Finance Innovation, part of Yole
Développement. Jérôme holds a Master of Physics from the University of Lyon (France).
Email: mouly@yole.fr
Medical Wearables: Market & Technology Analysis 2019 | Sample | www.yole.fr | ©2019
4
3M,AACTechnologies,Abbott,Alertgy,AliveCor,Amazon,Amphenol,AMS,Analog Devices,Apple,Artefact,Ava, BACtrack, Biogen,
Biolinq, Biometrics, Bittium, Bioserenity, Bloomlife, Bonbouton, Capsule, Cardionet, CarePredict, CareWear Corp, CEA Léti,
Cefaly Technology, Chrono Therapeutics, Chronolife, Comepa, Covestro, Dakota, Delsys, Dexcom, D Free, Ectosens, Elvie,
Empatica, Excelitas Technologies, Exosystems, Feel, Feetme, Fitbit, Food & Drug Administration, GI Logic, Global Kinetics,
Glucowise, Google, G-Tech Medical, Halo Neuroscience, Healthcare Origins, Healthwatch, Heimann Sensor, Hexoskin, Hocoma,
Honeywell, IBM, IHealth, Imec, Infineon, Insound, iRythm, JRC, Jari Electrode Supply, Johnson & Johnson, Knowles Acoustics, Kolo
Medical, Lifesense, Lifewatch, L’Oréal & La Roche-Posay, MC10, Maxim Integrated, Medatec, Medtronic, Merit Sensor, Melexis,
Microsoft, Micralyne, Monica Healthcare, Motiv, Murata, Muse, Mymdband, Neofect, Neucognic, NeuroMetrix, Novioscan, Nonin,
Novartis, Nuheara, Nuubo, NVK, NXP, Omron, Orpyx, Oska, OSRAM, Oticon, Oura, Pet Pace, Pfizer, Phonak, Philips Healthcare,
Philips Innovation Services, Pkvitality, Preventice, Qardiocore, Renesas, Resmed, ReSound GN, Robert Bosch, Roche, Rohm
Semiconductor, Senseonics, Sensimed AG, Sentio Solutions, Shade, Silicon Labs, SleepOn, SMI, Somnarus Inc , Sonova, Sonion,
Starkey, STMicroelectronics, Sunfriend,TDK,TE Connectivity,TempTraq,Tempdrop,The Electrode Store,Thync, UCB Pharma,
Upright,TTPVentus,Valencell,Verily,Vicardio,Vishay,VitalConnect,Vivosens Medical,Voyce,Wellbrain,Whistle,Withings,Wolfson,
Xiaomi, ZoLL,
…and many more.
LIST OF COMPANIES MENTIONED IN THIS REPORT
230+ slides of market and technology analysis
Information gathered through direct discussions with players all along the supply chain
Medical Wearables: Market & Technology Analysis 2019 | Sample | www.yole.fr | ©2019
5
THE OBJECTIVES OF THE REPORT
• Examine medical wearable device market trends, competitive forces and dynamics, and market drivers
• Offer an applications overview of medical wearables for diagnostic, therapeutic, and prevention, along with
disruptive technologies (products)
• Explain which sensors are used in which healthcare applications, and why
• Provide an overview of the main players at each level of the supply chain, with market share
• Furnish business models and market projections for 2018 – 2024
• Identify promising technologies and booming applications
• Deliver an overview of emerging flexible, stretchable, printed, and hybrid electronics for medical applications
Medical Wearables: Market & Technology Analysis 2019 | Sample | www.yole.fr | ©2019
6
SCOPE OF THE REPORT (1/3)
Medical wearables for patient activity monitoring and smart treatment
delivery
Medical wearables for people lacking autonomy and requiring
assistance and alerts
Medical wearables for animals activity monitoring
No prosthesis and implants (pacemakers, neuronal implants, retinal implant…)
No wellness, fitness devices and geolocation devices (sport smartwatch,
wellness wirst worn…)
Not included in the report’s scope
Medical Wearables: Market & Technology Analysis 2019 | Sample | www.yole.fr | ©2019
7
TIMELINE OF WEARABLES:A LITTLE BIT OF HISTORY
Thomas Jefferson:
introduced the first
pedometer to the
US
Thomish Meter
2009
2012
1788
1938
2019
Aurex Corp
developed the
1st wearables
hearing aid
Next step:
Medical devices
more
conformable
Hearing aid
Fitness tracking
Philips lifeline
Ingestible sensors and
wearables devices
Activity trackers,
wireless enables
wearable
technology
Proteus Digital Health
developed an ingestible
sensor approved by the
FDA in 2012 to
improve patients habits
…
Apple launched the
first approved
ECG integrated in
smartwatch
Single function
Multi-functions
Consumer fitness and sport
products enter the market
starting with Bluetooth
headset
2000
Appel’s ECG
Medical-functions
Medical Wearables: Market & Technology Analysis 2019 | Sample | www.yole.fr | ©2019
8
WHAT IS A WEARABLE MEDICAL DEVICE
Definitions
• According to the US Food and Drug Administration (FDA): a medical device is intended by its manufacturer to be
used for humans in order to :
• Diagnosis, prevention, monitoring, treatment or alleviation of disease.
• Diagnosis, monitoring, treatment, alleviation of or compensation for an injury or handicap.
• Investigation, replacement or modification of the anatomy or of a physiological process.
Can a wearable be a medical device?
• A wearable medical device is a device that is autonomous, noninvasive or minimally invasive, and that performs a
specific medical function such as health monitoring or prevention over a prolonged period of time which could be
long (>6hours) or short time (<1hour) of wearability.
• It includes a sensor technology which is able to collect data in a non invasive, reliable way and deliver information
about the surroundings in real-time.
• The term ‘‘wearable’’ implies that the support environment is either the human body or a piece of clothing.
Handheld and portable devices are therefore not strictly speaking wearable, but this distinction is not always clear as
it also depends on the conditions of their use.
• A medical wearable device, or an accessory to such a device, need to comply with the regulatory framework if it is
to be sold or distributed.
Wearable
medical
technologies
have emerged
as a growing
trend, with
challenges for
regulators
Medical Wearables: Market & Technology Analysis 2019 | Sample | www.yole.fr | ©2019
9
MEDICAL WEARABLES BUT FOR WHAT?
Information and data value
Reduce healthcare cost
• Wearables can replace some hospital
devices for homecare devices
• Daily monitoring of chronic disease
• Increased efficiency for doctors to
get access to patient data with less
administration
• Turn hospitals towards urgent cases
only
Improve patient adherence
• Check data and history of medication
• Alert/remind patient or family of any
risk for non-adherence
• Provide safer working conditions and
predict employee injuries and fatal
accidents because of fatigue or other
factors
• Develop a business model to improve
adherence (through insurance
incentives…)
Improve healthcare efficiency
• Great impact on both doctors and
patients, as they can be in constant
connectivity.
• Improved learning from daily
monitoring of patient reaction to
treatment
• Improve personalized medicine in
chronic disease and oncology
• Develop machine learning / artificial
intelligence
Move to preventive medicine
• Make wearables devices discreet and
easy to use for daily monitoring
• Develop incentives to help
monitoring vital signs
• Connect more data from
environment to prevent from events
Improve medical research
• Use data generated to better
understand medicine effects
• Use data generated to better prevent
events through population categories
• Engage pharmaceutical companies in
digital clinical trials
Medical Wearables: Market & Technology Analysis 2019 | Sample | www.yole.fr | ©2019
10
AN INCREASING NUMBER OF PRODUCTS WILL REACH THE MARKET*
* Non exhaustive list of products
Medical Wearables: Market & Technology Analysis 2019 | Sample | www.yole.fr | ©2019
11
SENSING TECHNOLOGY:WHAT CAN WE SENSE USING MEDICAL WEARABLES?
A wide variety
of wearable
devices
facilitate
personalized
healthcare
Monitoring and
tracking of behavioral
health brain, nerve
activity and stress
EEG
Diagnosis and monitoring
of chronic conditions
such as glucose level in
blood
Continuous monitoring of vital signs such
as cardiac arrhythmias and heart rate
enables whole health profiling, versus
today’s standard of sporadic sampling
CGM
Heart rate/ECG/optical sensors
Capture of local muscle
activation for rehabilitation,
motion study and tone
assessment
EMG
Superior mechanical
coupling to the body ,
reduces motion artifacts
that cause noise
Activity tracker
Superior thermal and
fluidic transport
Temperature &
galvanic skin response
UV sensing on the
body to prevent sun
damage
UV
Correction and
improvement of hearing
function
Hearing aids
microphones
Termophile sensors
Accelerometer Gyroscope
Pressure sensorsBiochips
Micropumps
Electrodes
Glucose sensors
Electrodes
Medical Wearables: Market & Technology Analysis 2019 | Sample | www.yole.fr | ©2019
12
AT SYSTEM LEVEL
A convergence
Consumer electronics
companies
Medical device
companies
Consumer
healthcare
• Good access to consumers
(distribution channels)
• Well known by consumers
• Lack of experience with medical
grade systems
• Not used to long-term development
(including clinical trials)
• Experience with medical grade
systems
• Reliable devices
• Lower access to volume market
• Low reputation in consumer
marketMedical Wearables: Market & Technology Analysis 2019 | Sample | www.yole.fr | ©2019
13
M&A, COLLABORATIONS, FUNDRAISING AND RELEASED PRODUCTS SINCE 2016
Analysis of the strategic moves in the industry
• Definition of medical wearables and history
• The transition from fitness and sport to medical wearables and identification of new products
• Who are the main players and the new entrants developing new medical devices for the market?
• What strategic moves are driving the medical wearables market growth?
Medical Wearables: Market & Technology Analysis 2019 | Sample | www.yole.fr | ©2019
14
MARKET DATA AND FORECASTS
• Market data and forecasts 2018-2024 for per medical wearable systems
• Market data and forecasts 2018-2024 for per sensor types
• Market share and dynamics per segment for 2018
Medical Wearables: Market & Technology Analysis 2019 | Sample | www.yole.fr | ©2019
15
MARKET TRENDS AND KEY APPLICATIONS
• Market segmentation depending on key technological and economical/behavioral criteria
• Each segment has its whole chapter with detailed description, market data, key products examples, key
players, requirements and market insights.
• Development timeline and price analysis of medical wearable devices
Medical Wearables: Market & Technology Analysis 2019 | Sample | www.yole.fr | ©2019
16
ANALYSIS OF TECHNOLOGY TRENDS
• Description of the technological challenges and technical requirements, focus on sensors technology
• Key players developing technologies for medical wearables and technology roadmap, a dedicated chapter
describing and analyzing who is developing what
• What are the sweet spots for today and tomorrow
Medical Wearables: Market & Technology Analysis 2019 | Sample | www.yole.fr | ©2019
• Description of the technological challenges and technical requirements, focus on sensors technology
• Key players developing technologies for medical wearables and technology roadmap, a dedicated chapter
describing and analyzing who is developing what
• What are the sweet spots for today and tomorrow
17
SUPPLY CHAIN ANALYSIS
• Detailed supply chain and collaboration examples
• Who’s producing in-house, who is outsourcing, for which volumes?
• How can companies all along the supply chain make value with medical wearables?
• Regulation and market access
Medical Wearables: Market & Technology Analysis 2019 | Sample | www.yole.fr | ©2019
18
RELATED REPORTS
BioMEMS & Non-Invasive Sensors: Microsystems for Life Sciences & Healthcare 2018
Connected Medical Devices Market and Business Models 2017
Ultrasound SensingTechnologies for Medical, Industrial and Consumer Applications 2018
Medical Wearables: Market & Technology Analysis 2019 | Sample | www.yole.fr | ©2019
In today’s wearable technology market, the vast
majority of growth has been in consumer sports,
fitness, and wellness. However, wearable devices
are rapidly expanding for health and medical
uses, and are expected to reach a market value
of $32B by 2024. Smartphone ubiquity, sensor
miniaturization, and ease of integration have
increased the number of wearable products on
the market, to the point where such products
are now achieving performance levels suitable for
medical use-cases. But how will medical wearables
make patients healthier - and why now?
Medical wearables’ purpose is to monitor a patient’s
vital signs in order to prevent health issues, as well
as contribute to treatment and rehabilitation.
Wearable makers face the same challenges
long associated with the medical industry - for
example, the need for several layers of validation,
i.e. a CE mark and FDA approval. However, with
the increasing prevalence of chronic diseases like
cardiovascular issues and diabetes (approx. 425M
diabetics worldwide), medical wearables’ huge
upside far outweighs the red tape involved.
An increasing number of wearable devices are
approaching medical-grade level: for instance,
the Ava wristband, Apple watch, Cefaly patch,
and Ectosens patch, along with smartwatches
from Omron and Verily. But even though these
products hold considerable promise as consumer
medical wearables, they still must be comfortable
and easy to use, with functions serving very
different purposes from activity tracking to
glucose monitoring, through atrial fibrilation
detection. And what about the Apple Watch
Series 4 that was supposedly FDA-approved not
so long ago: was this a real event? This segues into
another important discussion: what to do with the
data, who will exploit the data (and how), and for
what purpose?
This report details these new product launches
and describes what is in the pipeline. Yole
Développement's (Yole) analysts also explore
the medical wearable technologies used across
different market segments, highlight the reasons
why such technologies are used, and discuss how
they could evolve.
MEDICAL WEARABLES
Market & Technology report - March 2019
New technologies and faster market launches are driving the medical wearables market.
REPORT’S KEY FEATURES
•	Yole Développement's vision and
definition of medical wearables
•	Analysis of market dynamics for
human and veterinary monitoring,
therapeutics, and prevention
•	Medical wearables’ technical and
economic requirements?
•	Key challenges at system and
sensor level
•	Market segmentation including
main players, product examples,
and market share for each segment
•	Market data and forecasts for the
period 2018 - 2024 for systems
and sensors
•	Regulatory, market access, and
target customers in the USA,
Europe, and China
•	Technology trends and supply
chain, along with business models
adopted by this field’s key players
OBJECTIVES OF THE REPORT
•	Examine medical wearable device
market trends, competitive forces
and dynamics, and market drivers
•	Offer an applications overview of
medical wearables for diagnostic,
therapeutic, and prevention,
along with disruptive technologies
(products)
•	Explain which sensors are used in
which healthcare applications, and
why
•	Provide an overview of the main
players at each level of the supply
chain, with market share
•	Furnish business models and
market projections for 2018 - 2024
•	Identify promising technologies
and booming applications
•	Deliver an overview of emerging
flexible, stretchable, printed, and
hybrid electronics for medical
applications
(Yole Développement, March 2019)
MEDICAL WEARABLES AND SENSORS ECOSTYSTEM IS MATURING
TO SUSTAIN 31% MARKET GROWTH!
The overall market for medical wearable devices
will grow at a rate of 31% year-over-year, reaching
more than $32B in 2024. In the meantime, the global
sensor market for medical wearables, including
continuous glucose monitoring (CGM), is expected
to reach $2.8B in 2024, with a compound annual
growth rate (CAGR) of 21.6% from 2018 - 2024.
Led by the Apple Watch Series 4, there is
increasingly strong interest to add ECG capability
in a smartwatch so that doctors and hospitals can
get accurate information on a patient’s cardiac
status. At sensor level, increasing complexity of
medical wearables turns electronic companies to
medical grade sensor experts, like AMS, Maxim
Integrated or Valencell developing dedicated
platforms. It enables an optimized integration (in
terms of footprint and power consumption) while
reducing development time with the guarantee of
measurement accuracy.
Timeline of wearables: a little bit of history
HOW MEDICAL WEARABLES WILL MAKE PATIENTS HEALTHIER
Thomas Jefferson:
introduced the first
pedometer to the
US
Thomish Meter
2009
2012
1788
1938
2019
Aurex Corp
developed the
1st wearables
hearing aid
Next step:
Medical devices
more
conformable
Hearing aid
Fitness tracking
Philips lifeline
Ingestible sensors and
wearables devices
Activity trackers,
wireless enables
wearable
technology
Proteus Digital Health
developed an ingestible
sensor approved by the
FDA in 2012 to
improve patients habits
…
Apple launched the
first approved
ECG integrated in
smartwatch
Single function
Multi-functions
Consumer fitness and sport
products enter the market
starting with Bluetooth
headset
2000
Appel’s ECG
Medical-functions
MEDICAL WEARABLES: MARKET AND TECHNOLOGY TRENDS 2019
Medical wearables today - convergence of two worlds
(Yole Développement, March 2019)
REMAINING CHALLENGES, BUT A MYRIAD OF ADVANCED TECHNOLOGIES ARE
UNDER DEVELOPMENT TO SOLVE THE ISSUES
Medical wearables are the convergence of two
worlds: the world of medical-grade devices and the
world of consumer wearables. Medical wearables
also feature two major player types: medical device
manufacturers willing to reach consumer healthcare
with the promise of higher volumes, and consumer
device companies willing to reach the high-value
healthcare market. Medical wearables development is
quickening and competition is intensifying, prompting
players to ensure a high level of quality as well as
medical-grade accuracy for the generated data.
Sensor and electronics manufacturers are facilitating
a faster time-to-market via optimized modules
that are ready for integration. For example, a
photoplethysmogram (PPG) device for heart-rate
measurement combines, among other elements, LEDs
and a photodiode. The LEDs emit light through the
skin to the blood vessels, and the photodiode receives
the unabsorbed portion of light. Sensor designers are
developing sensor modules that integrate LEDs and
photodiode with the right packaging and electronic
architecture, ensuring accuracy of measurement
with miniaturized, low-power devices. These turnkey
solutions contribute to a faster time-to-market for
medical wearable makers and help sensor makers
move up the value chain with high-value solutions.
Ahighlevelofintegrationandlow-powerconsumption
are not the only challenges described in this report,
which aims to answer the question, “What could be
the key enabling technologies for medical wearables?”
Readers will also discover how medical wearable
players investigate innovative materials and solutions
that meet the patient’s requirements for comfort and
painless monitoring. Supple, conformable materials
using printed electronic technologies should
increasingly benefit high-quality measurement and
help avoid errors due to patient movement.
This report describes the technology trends and
roadmaps that promote a better understanding of
how the medical wearables industry and its players
are answering patient and user requirements while
contributing to lower overall healthcare costs.
Since 2014, Yole Développement's analysts have
identified more than $550M raised by medical
device and diagnostic companies, and the pace
at which new medical wearable products are
being commercialized is accelerating. Moreover,
investments in different acquisitions between large
diagnostic companies and consumer companies
(i.e. Apple acquiring Glimpse, Medtronic acquiring
Nutrino,…) amount to an impressive $900M since
2016, further confirming the medical wearable
market’s positive dynamic.
Pharmaceutical companies are also turning to
wearables in order to improve RD through strategic
collaborations. For example, Pfizer, UCB Pharma,
Apple, J  J, and IBM are just some of the companies
testing mobile technology for patients with
Parkinson’s. As well, smartwatches and wristband
generates information for the consumer, with a clear
objective to be later prescribed and work with health
insurance and doctors.
In this context, Yole’s report provides market data and
forecasts along with a focus on the emerging business
models.
Volume
Time
1M
10M
• From discrete to dedicated platform
• Turnkey solution
• Time to market optimization for short
cycle times
Long cycle time Application
oriented 'prescribed medical devices'
Short cycle time Application
oriented 'consumer healthcare'
Photo credits: Osram
Medical wearables and sensors: 2018 – 2024 market forecast (in B$)
(Yole Développement, March 2019)
0
0.5
1
1.5
2
2.5
3
3.5
4
4.5
5
0
5
10
15
20
25
30
35
2018 2019 2020 2021 2022 2023 2024
Veterinary
Maternal  neonatal care
Medical prevention
Rehabilitations systems  therapeutics
Metabolic  cardiovascular monitoring
Respiratory  movement disorder
Glucose monitoring  drug delivery
Sensors for wearables
Medical wearables:
CAGR2018-2024 : 31%
Sensors:
CAGR2018-2024 : 21,6%Medicalwearables
Sensors
Medical wearables segments:
MARKET  TECHNOLOGY REPORT
COMPANIES CITED IN THE REPORT (non exhaustive list)
3M, AAC Technologies, Abbott, Alertgy, AliveCor, Amazon, Amphenol, AMS, Analog
Devices , Apple, Artefact, Ava, BACtrack, Biogen, Biolinq, Biometrics, Bittium, Bioserenity,
Bloomlife, Bonbouton, Capsule, Cardionet, CarePredict, CareWear Corp, CEA Léti, Cefaly
Technology, Chrono Therapeutics, Chronolife, Comepa, Covestro, Dakota, Delsys, Dexcom,
D Free, Ectosens, Elvie, Empatica, Excelitas Technologies, Exosystems, Feel, Feetme, Fitbit,
Food  Drug Administration, GI Logic, Global Kinetics, Glucowise, Google, G-Tech Medical,
Halo Neuroscience, Healthcare Origins, Healthwatch, Heimann Sensor, Hexoskin, Hocoma,
Honeywell, IBM, IHealth, Imec, Infineon, Insound, iRythm, JRC, Jari Electrode Supply, Johnson
 Johnson, Knowles Acoustics, Kolo Medical, Lifesense, Lifewatch, L’Oréal  La Roche-Posay,
MC10, Maxim Integrated, Medatec, Medtronic, Merit Sensor, Melexis, Microsoft, Micralyne,
Monica Healthcare, Motiv, Murata, Muse, Mymdband, Neofect, Neucognic, NeuroMetrix,
Novioscan, Nonin, Novartis, Nuheara, Nuubo, NVK, NXP, Omron, Orpyx, Oska, OSRAM,
Oticon, Oura, Pet Pace, Pfizer, Phonak, Philips Healthcare, Philips Innovation Services,
Pkvitality, Preventice, Qardiocore, Renesas, Resmed, ReSound GN, Robert Bosch, Roche,
Rohm Semiconductor, Senseonics, Sensimed AG, Sentio Solutions, Shade, Silicon Labs,
SleepOn, SMI, Somnarus Inc , Sonova, Sonion, Starkey, STMicroelectronics, Sunfriend, TDK,
TE Connectivity, TempTraq, Tempdrop, The Electrode Store, Thync, UCB Pharma, Upright,
TTP Ventus, Valencell, Verily, Vicardio, Vishay, VitalConnect, Vivosens Medical, Voyce,
Wellbrain, Whistle, Withings, Wolfson, Xiaomi, ZoLL, and many more...
Find more
details about
this report here:
RELATED REPORTS
Benefit from our Bundle  Annual Subscription offers and access our analyses at the best available
price and with great advantages
• Connected Medical Devices Market and
Business Models 2017
• Ultrasound Sensing Technologies for Medical,
Industrial and Consumer Applications 2018
Find all our reports on www.i-micronews.com
As a Technology  Market
Analyst, Biotechnologies
 Molecular Innovations,
Medical Technologies in the Life Sciences 
Healthcare division at Yole Développement
(Yole), Asma Siari is involved in the
development of technology  market
reports as well as the production of custom
consulting projects. After a Master’s degree
in Biotechnologies, Diagnostic Therapeutics
 Management, Asma served as Research
Assistant at the Moores Cancer Center
(San Diego, CA). She is a coauthor in
three scientific publications published in
the Molecular Cancer Research Journal.
Asma Siari graduated with an Advanced
Master’s degree in International Strategy
 Marketing BtoB from EM Lyon Business
School (France).
AUTHORS
 TABLE OF CONTENTS (complete content on i-Micronews.com)
Executive summary 	 08
Context 	 28
 Definition of medical wearables
 A little bit of history
 What’s new?
 Product launches, collaborations, and
fundraising
Market forecasts 	 53
 Global market data and market forecasts
 Market data and forecasts 2018-2024 in
$M, by segment
 Market forecasts, by sensor type
 Market share
Market trends	 69
 Market drivers and challenges
 RD development time, and related
investments
 Market segmentation and segment
description
 Technology requirements/application
 Key players/segment
 Top medical devices: how do they position
themselves?
 Technology trends
 Technological description of sensors for
medical wearables
 Sensors
 Manufacturing process and materials
 Roadmaps
 Overview of emerging flexible, stretchable,
printed, and hybrid electronics for medical
applications
Technology trends 	 132
 Technological description of sensors for
medical wearables
 Sensors
 Manufacturing process and materials
 Roadmaps
 Overview of emerging flexible, stretchable,
printed, and hybrid electronics for medical
applications
Supply chain	 185
 Ecosystems
 Business models and players’ strategy
 Supply chain analysis
 Regulation and reimbursement aspects
 Market access
 Technical challenges regarding fabrication,
packaging, and assembly techniques
 Conclusion
 Perspectives
 What’s next
Conclusion 	 233
Jérôme Mouly serves
as a Senior Technology 
Market Analyst  Business
Developer specialized in microtechnologies
for inkjet  bioMEMS sensors at
Yole Développement (Yole). Jérôme is
supporting the development of strategic
projects, following leading customers of
the company, within the Life Sciences
 Healthcare division. Since 2000, he is
also engaged in more than 100 marketing
and technological analyses for industrial
groups, start-ups and institutes related
to semiconductor  medical technologies
industry, in the field of inkjet functional
printing, wearable sensors and connected
medical devices. Jérôme is also regularly
involved in international conferences, giving
presentations and delivering keynotes.
Jérôme Mouly holds a Master of Physics from
the University of Lyon (France).
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+ 1 310 600-8267 – laferriere@yole.fr
• Eastern US  Canada - Troy Blanchette:
+1 704 859 0453 – troy.blanchette@yole.fr
• Europe  RoW - Lizzie Levenez:
+ 49 15 123 544 182 – levenez@yole.fr
• Japan  Rest of Asia - Takashi Onozawa:
+81-80-4371-4887 – onozawa@yole.fr
• Greater China - Mavis Wang:
+886 979 336 809 – wang@yole.fr
• Specific inquiries: +33 472 830 180 – info@yole.fr
(1)
Our Terms and Conditions of Sale are available at
www.yole.fr/Terms_and_Conditions_of_Sale.aspx
The present document is valid 24 months after its publishing date:
March 14, 2019
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ABOUT YOLE DEVELOPPEMENT
BILL TO
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- The report will be ready for delivery from March 29, 2019
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delivered electronically at payment reception. For French customers,
add 20% for VAT
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Founded in 1998, Yole Développement has grown to become a group of companies providing marketing, technology and strategy consulting, media and
corporate finance services, reverse engineering and reverse costing services and well as IP and patent analysis. With a strong focus on emerging applications
using silicon and/or micro manufacturing, the Yole group of companies has expanded to include more than 80 collaborators worldwide covering MEMS and Image
Sensors, Compound Semiconductors, RF Electronics, Solid-State Lighting, Displays, Software, Optoelectronics, Microfluidics  Medical, Advanced Packaging,
Manufacturing, Nanomaterials, Power Electronics and Batteries  Energy Management.
The “More than Moore” market research, technology and strategy consulting company Yole Développement, along with its partners System Plus Consulting,
PISEO and KnowMade, support industrial companies, investors and RD organizations worldwide to help them understand markets and follow technology
trends to grow their business.
CONSULTING AND ANALYSIS
• Market data  research, marketing analysis
• Technology analysis
• Strategy consulting
• Reverse engineering  costing
• Patent analysis
• Design and characterization of innovative optical systems
• Financial services (due diligence, MA with our partner)
More information on www.yole.fr
MEDIA  EVENTS
• i-Micronews.com website  related @Micronews e-newsletter
• Communication  webcast services
• Events: TechDays, forums…
More information on www.i-Micronews.com
REPORTS
• Market  technology reports
• Patent investigation and patent infringement risk analysis
• Structure, process and cost analysis
• Cost simulation tool
More information on www.i-micronews.com/reports
CONTACTS
For more information about :
• Consulting  Financial Services: Jean-Christophe Eloy (eloy@yole.fr)
• Reports: David Jourdan (jourdan@yole.fr) Yole Group of Companies
• Press Relations  Corporate Communication: Sandrine Leroy (leroy@yole.fr)
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SALES CONTACTS
• Western US  Canada - Steve Laferriere:
+ 1 310 600-8267 – laferriere@yole.fr
• Eastern US  Canada - Troy Blanchette:
+1 704 859 0453 – troy.blanchette@yole.fr
• Europe  RoW - Lizzie Levenez:
+ 49 15 123 544 182 – levenez@yole.fr
• Japan  Rest of Asia - Takashi Onozawa:
+81-80-4371-4887 – onozawa@yole.fr
• Greater China - Mavis Wang:
+886 979 336 809 – wang@yole.fr
• Specific inquiries: +33 472 830 180 – info@yole.fr
(1)
Our Terms and Conditions of Sale are available at
www.yole.fr/Terms_and_Conditions_of_Sale.aspx
The present document is valid 24 months after its publishing date:
March 14, 2019
/
ABOUT YOLE DEVELOPPEMENT
BILL TO
Name (Mr/Ms/Dr/Pr):
Job Title:
Company:
Address:
City:
State:
Postcode/Zip:
Country*:
*VAT ID Number for EU members:
Tel:
Email:
Date:
PRODUCT ORDER - Ref YD19008
Please enter my order for above named report:
	 One user license*: Euro 5,990
	 Multi user license: Euro 6,490
- The report will be ready for delivery from March 29, 2019
- For price in dollars, please use the day’s exchange rate. All reports are
delivered electronically at payment reception. For French customers,
add 20% for VAT
I hereby accept Yole Développement’s Terms and Conditions of Sale(1)
Signature:
*One user license means only one person at the company can use the report.
Founded in 1998, Yole Développement has grown to become a group of companies providing marketing, technology and strategy consulting, media and
corporate finance services, reverse engineering and reverse costing services and well as IP and patent analysis. With a strong focus on emerging applications
using silicon and/or micro manufacturing, the Yole group of companies has expanded to include more than 80 collaborators worldwide covering MEMS and Image
Sensors, Compound Semiconductors, RF Electronics, Solid-State Lighting, Displays, Software, Optoelectronics, Microfluidics  Medical, Advanced Packaging,
Manufacturing, Nanomaterials, Power Electronics and Batteries  Energy Management.
The “More than Moore” market research, technology and strategy consulting company Yole Développement, along with its partners System Plus Consulting,
PISEO and KnowMade, support industrial companies, investors and RD organizations worldwide to help them understand markets and follow technology
trends to grow their business.
CONSULTING AND ANALYSIS
• Market data  research, marketing analysis
• Technology analysis
• Strategy consulting
• Reverse engineering  costing
• Patent analysis
• Design and characterization of innovative optical systems
• Financial services (due diligence, MA with our partner)
More information on www.yole.fr
MEDIA  EVENTS
• i-Micronews.com website  related @Micronews e-newsletter
• Communication  webcast services
• Events: TechDays, forums…
More information on www.i-Micronews.com
REPORTS
• Market  technology reports
• Patent investigation and patent infringement risk analysis
• Structure, process and cost analysis
• Cost simulation tool
More information on www.i-micronews.com/reports
CONTACTS
For more information about :
• Consulting  Financial Services: Jean-Christophe Eloy (eloy@yole.fr)
• Reports: David Jourdan (jourdan@yole.fr) Yole Group of Companies
• Press Relations  Corporate Communication: Sandrine Leroy (leroy@yole.fr)
© 2019
Yole Développement
FromTechnologies to Market
Source: Wikimedia Commons
2©2019 | www.yole.fr | About Yole Développement
YOLE DEVELOPPEMENT – FIELDS OF EXPERTISE
Life Sciences
 Healthcare
o Microfluidics
o BioMEMS  Medical Microsystems
o Inkjet and accurate dispensing
o Solid-State Medical Imaging  BioPhotonics
o BioTechnologies
Power
Wireless
o RF Devices Technologies
o Compound Semiconductors  Emerging Materials
o Power Electronics
o Batteries  Energy Management
Semiconductor
 Software
o Package,Assembly  Substrates
o Semiconductor Manufacturing
o Memory
o Software  Computing
Photonics,
Sensing  Display
o Solid-State Lighting
o Display
o MEMS, Sensors  Actuators
o Imaging
o Photonics  Optoelectronics
Semiconductor
 Software
Power Wireless
Photonics,
Sensing
 Display
Life
Sciences 
Healthcare
3©2019 | www.yole.fr | About Yole Développement
4 BUSINESS MODELS
o Consulting and Analysis
• Market data  research,
marketing analysis
• Technology analysis
• Strategy consulting
• Reverse engineering  costing
• Patent analysis
• Design and characterization
of innovative optical systems
• Financial services (due
diligence, MA with our
partner)
www.yole.fr
o Syndicated reports
• Market  technology reports
• Patent investigation and patent
infringement risk analysis
• Teardowns  reverse costing
analysis
• Cost simulation tool
www.i-Micronews.com/reports o Media
• i-Micronews.com website
• @Micronews e-newsletter
• Communication  webcast
services
• Events:TechDays, forums,…
www.i-Micronews.com
o Monitors
• Monthly and/or Quarterly
update
• Excel database covering supply,
demand, and technology
• Price, market, demand and
production forecasts
• Supplier market shares
www.i-Micronews.com/reports
4©2019 | www.yole.fr | About Yole Développement
6 COMPANIES TO SERVEYOUR BUSINESS
Due diligence
www.yole.fr
Manufacturing costs analysis
Teardown and reverse engineering
Cost simulation tools
www.systemplus.fr
Market, technology and strategy
consulting
www.yole.fr
IP analysis
Patent assessment
www.knowmade.fr
Innovation and business maker
www.bmorpho.com
Design and characterization of
innovative optical systems
www.piseo.fr
Yole Group of Companies
5©2019 | www.yole.fr | About Yole Développement
OUR GLOBAL ACTIVITY
30%of our business
40%of our business
30%of our business
Greater
China office
Yole Japan
HQ in Lyon
Nantes
Paris
Nice
Vénissieux
Europe office
Frankfurt
Hsinchu
Tokyo
Yole Inc.
Phoenix
Yole Korea
Seoul
Palo Alto
6©2019 | www.yole.fr | About Yole Développement
ANALYSIS SERVICES - CONTENT COMPARISON
Technology
and Market
Report
Leadership
Meeting
QA
Service
Depth of the analysis
Breadthoftheanalysis
Meet the
Analyst
Custom
Analysis
High
High
Low
7©2019 | www.yole.fr | About Yole Développement
SERVING THE ENTIRE SUPPLY CHAIN
Our analysts
provide
market
analysis,
technology
evaluation,
and business
plans along
the entire
supply chain
Integrators, end-
users and software
developers
Device manufacturers
Suppliers: material, equipment,
OSAT, foundries…
Financial investors, RD centers
8©2019 | www.yole.fr | About Yole Développement
SERVING MULTIPLE INDUSTRIAL FIELDS
We work
across
multiples
industries to
understand
the impact of
More-than-
Moore
technologies
from device
to system
From A to Z…
Transportation
makers
Mobile phone
and
consumer
electronics
Automotive
Medical
systems
Industrial
and defense
Energy
management
9©2019 | www.yole.fr | About Yole Développement
o Over the course of more than 20 years, Yole Développement has grown to become a group of companies. Together with System Plus Consulting and KnowMade, we now
provide marketing, technology and strategy consulting, media and corporate finance services, reverse costing, structure, process and cost analysis services and well as
intellectual property (IP) and patent analysis. Together, our group of companies is collaborating ever closer and therefore will offer, in 2019, a collection of over 125 reports
and 10 new monitors. Combining respective expertise and methodologies from the three companies, they cover:
o If you are looking for:
• An analysis of your product market and technology
• A review of how your competitors are evolving
• An understanding of your manufacturing and production costs
• An understanding of your industry’s technology roadmap and related IPs
• A clear view supply chain evolution
Our reports and monitors are for you!
o Our team of over 70 analysts, including PhD and MBA qualified industry veterans from Yole Développement, System Plus Consulting and KnowMade, collect information,
identify trends, challenges, emerging markets, and competitive environments. They turn that information into results and give you a complete picture of your industry’s
landscape. In the past 20 years, we have worked on more than 2,000 projects, interacting with technology professionals and high-level opinion makers from the main
players of their industries and realized more than 5,000 interviews per year.
WHAT TO EXPECT IN 2019?
In 2019 we will extend our offering with a new ‘monitor’ product which provides more updates on your industry during the year. The Yole Group of Companies is also building
on and expanding its investigations of the memory industry. Moreover, in parallel, the Yole Group reaffirms its commitment to a new collection of reports mixing software and
hardware and is increasing its involvement in displays, radio-frequency (RF) technology, advanced substrates, batteries and compound semiconductors. Discover our 2019
program right now, and ensure you get a true vision of the industry. Stay tuned!
REPORTS COLLECTION
www.i-Micronews.com
• MEMS  Sensors
• RF devices  technologies
• Medical technologies
• Semiconductor Manufacturing
• Advanced packaging
• Memory
• Batteries and energy management
• Power electronics
• Compound semiconductors
• Solid state lighting
• Displays
• Software
• Imaging
• Photonics
10©2019 | www.yole.fr | About Yole Développement
OUR 2019 REPORTS COLLECTION (1/4)
18 fields of excellence combined with six markets to provide a complete picture of your industry landscape
Market –Technology – Strategy – byYole Développement
Yole Développement (Yole) offers market reports including quantitative market forecasts,
technology trends, company strategy evaluation and indepth application analyses. Yole will
publish more than 55 reports in 2019, with our partner PISEO contributing to some of
the lighting reports.
Reverse Costing® – Structure, Process and Cost Analysis – by
System Plus Consulting
The Reverse Costing® report developed by System Plus Consulting provides full
teardowns, including detailed photos, precise measurements, material analyses,
manufacturing process flows, supply chain evaluations, manufacturing cost analyses and
selling price estimations. The reports listed below are comparisons of several analyzed
components from System Plus Consulting. More reports are however available, and over
60 reports will be released in 2019.The complete list is available at www.systemplus.fr.
Patent Reports – by KnowMade
More than describing the status of the IP situation, these analyses provide a missing link
between patented technologies and market, technological and business trends. They offer
an understanding of the competitive landscape and technology developments from a
patent perspective. They include key insights into key IP players, key patents and future
technology trends. For 2019 KnowMade will release over 15 reports.
The markets targeted are :
• Mobile  Consumer
• Automotive Transportation
• Medical
• Industrial
• Telecom  Infrastructure
• Defense  Aerospace
• Linked reports are dealing with the same topic to provide
• a more detailed analysis.
11©2019 | www.yole.fr | About Yole Développement
OUR 2019 REPORTS COLLECTION (1/5)
18 fields of excellence combined with six markets to provide a complete picture of your industry landscape
MEMS  SENSORS
o MARKET ANDTECHNOLOGY REPORT
• Status of the MEMS Industry 2019 - Update
• Status of the Audio Industry 2019 - New
• Uncooled Infrared Imagers and Detectors 2019 – Update
• Consumer Biometrics:Technologies and MarketTrends 2018
• MEMS Pressure Sensor Market and Technologies 2018
• Gas  Particle Sensors 2018
o STRUCTURE, PROCESS  COST REPORT
• MEMS  Sensors Comparison 2019
• MEMS Pressure Sensor Comparison 2018
• Particle Sensors Comparison 2019
• Miniaturized Gas Sensors Comparison 2018
o PATENT REPORT
• MEMS Foundry Business Portfolio 2019 - New
• Miniaturized Gas Sensors 2019 - New
PHOTONIC AND OPTOELECTRONICS
o MARKET ANDTECHNOLOGY REPORT
• Photonic Integrated Circuit 2019 - New
• LiDARs for Automotive and Industrial Applications 2019 - Update
• Silicon Photonics 2018
o PATENT REPORT
• Silicon Photonics for Data Centers: Optical Transceiver 2019 - New
• LiDAR for Automotive 2018
RF DEVICES ANDTECHNOLOGIES
o MARKET ANDTECHNOLOGY REPORT
• RF GaN Market:Applications, Players,Technology,
and Substrates 2019 - Update
• 5G’s Impact on RF Front-End Module and Connectivity
for Cell Phones 2019 – Update
• 5G Impact on Wireless Infrastructure 2019
• Radar andV2X Market  Technology for Automotive 2019 - Update
• Advanced RF Antenna Market  Technology 2019 - New
• RF Standards and Technologies for Connected Objects 2018
o STRUCTURE, PROCESS  COST REPORT
• RF Front-End Module Comparison 2019 - Update
• Automotive Radar RF Chipset Comparison 2018
o PATENT REPORT
• Antenna for 5G Wireless Communications 2019 - New
• RF Front End Modules for Cellphones 2018
• RF Filter for 5G Wireless Communications: Materials and Technologies 2019
• RF GaN : Materials, Devices and Modules 2018
Update : 2018 version still available
12©2019 | www.yole.fr | About Yole Développement
OUR 2019 REPORTS COLLECTION (2/5)
18 fields of excellence combined with six markets to provide a complete picture of your industry landscape
IMAGING
o MARKET ANDTECHNOLOGY REPORT
• Status of the CIS Industry 2019:Technology
and Foundry Business - Update
• Imaging for Automotive 2019 - Update
• NeuromorphicTechnologies for Sensing 2019 - Update
• Status of the CCM and WLO Industry 2019 - Update
• MachineVision for Industry and Automation 2018
• Sensors for RoboticVehicles 2018
o STRUCTURE, PROCESS  COST REPORT
• Compact Camera Modules Comparison 2019
• CMOS Image Sensors Comparison 2019
o PATENT REPORT
• Facial  Gesture Recognition Technlogies in Mobile Devices 2019 - New
• Apple iPhone X Proximity Sensor  Flood Illuminator 2018
MEDICAL IMAGING AND BIOPHOTONICS
o MARKET ANDTECHNOLOGY REPORT
• X-Ray Detectors for Medical, Industrial
• and Security Applications 2019- New
• Microscopy Life Science Cameras: Market and Technology Analysis 2019
• Ultrasound technologies for Medical, Industrial
and Consumer Applications 2018
o PATENT REPORT
• Optical Coherence Tomography Medical Imaging 2018
MICROFLUIDICS
o MARKET ANDTECHNOLOGY REPORT
• Status of the Microfluidics Industry 2019 - Update
• Next Generation Sequencing  DNA Synthesis - Technology,
Consumables Manufacturing and MarketTrends 2019 - New
• Organ-on-a-Chip Market  Technology Landscape 2019 - Update
• Point-of-Need Testing Application of MicrofluidicTechnologies 2018
• Liquid Biopsy: from Isolation to Downstream Applications 2018
• Chinese Microfluidics Industry 2018
o PATENT REPORT
• Microfluidic ManufacturingTechnologies 2019 – New
INKJET AND ACCURATE DISPENSING
o MARKET ANDTECHNOLOGY REPORT
• Inkjet Printheads - Dispensing Technologies
 Market Landscape 2019 - Update
• Emerging Printing Technologies
for Microsystem Manufacturing 2019 - New
• Piezoelectric Materials from Bulk to Thin Film 2019 - New
• Inkjet Functional and Additive Manufacturing for Electronics 2018
o STRUCTURE, PROCESS  COST REPORT
• Piezoelectric Materials from Bulk to Thin Film Comparison 2019
Update : 2018 version still available
13©2019 | www.yole.fr | About Yole Développement
OUR 2019 REPORTS COLLECTION (3/5)
18 fields of excellence combined with six markets to provide a complete picture of your industry landscape
BIOTECHNOLOGIES
o MARKET ANDTECHNOLOGY REPORT
• CRISPR-Cas9 Technology: From Lab to Industries 2018
o PATENT REPORT
• Personalized Medicine 2019 – New
BIOMEMS  MEDICAL MICROSYSTEMS
o MARKET ANDTECHNOLOGY REPORT
• Medical Wearables: Market  Technology Analysis 2019 - New
• Neurotechnologies and Brain Computer Interface 2018
• BioMEMS  Non-Invasive Sensors: Microsystems for Life Sciences
 Healthcare 2018
o PATENT REPORT
• 3D Cell Printing 2019 - New
• CirculatingTumor Cells Isolation 2019 - New
• Nanopore Sequencing 2019 - New
SOFTWARE AND COMPUTING
o MARKET ANDTECHNOLOGY REPORT
• Artificial Intelligence Computing For Automotive 2019 - New
• Hardware and Software for Artificial Intelligence (AI)
in Consumer Applications 2019 - Update
• From Image Processing to Deep Learning 2019 - Update
• xPU (Processing Units) for Cryptocurrency, Blockchain, HPC
and Gaming 2019 – New
MEMORY
o MARKET ANDTECHNOLOGY REPORT
• Status of the Memory Business 2019 - New
• MRAM Technology and Business 2019 - New
• Emerging NonVolatile Memory 2018
o STRUCTURE, PROCESS  COST REPORT
• Memory Comparison 2019
o PATENT REPORT
• Magnetoresistive Random-Access Memory (MRAM) 2019 - New
• 3D Non-Volatile Memory 2018
ADVANCED PACKAGING
o MARKET ANDTECHNOLOGY REPORT
• Fan Out PackagingTechnologies and MarketTrends 2019 - Update
• 3D TSV Integration and Monolithic Business Update 2019 - Update
• Advanced RF SiP for Cellphones 2019 - Update
• Status of Advanced Packaging 2019 - Update
• Status of Advanced Substrates 2019 - Update
• Panel Level PackagingTrends 2019 - Update
• System in Package (SiP) Technology and Market Trends 2019 - New
• Trends in Automotive Packaging 2018
• Thin-Film Integrated Passive Devices 2018
o STRUCTURE, PROCESS  COST REPORT
• Advanced RF SiP for Cellphones Comparison 2019
Update : 2018 version still available
14©2019 | www.yole.fr | About Yole Développement
OUR 2019 REPORTS COLLECTION (4/5)
18 fields of excellence combined with six markets to provide a complete picture of your industry landscape
SEMICONDUCTOR MANUFACTURING
o MARKET ANDTECHNOLOGY REPORT
• Nano Imprint Lithography 2019 - New
• Equipment and Materials for Fan Out Packaging 2019 - Update
• Equipment for More than Moore:Thin Film Deposition
 Etching 2019 - New
• Wafer Starts for More Than Moore Applications 2018
• Polymeric Materials atWafer-Level
for Advanced Packaging 2018
• Bonding and Lithography Equipment Market
for More than Moore Devices 2018
o STRUCTURE, PROCESS  COST REPORT
• Wafer Bonding Comparison 2018
o PATENT REPORT
• Hybrid Bonding for 3D Stack 2019 – New
SOLID STATE LIGHTING
o MARKET ANDTECHNOLOGY REPORT
• Status of the Solid State Light Source Industry 2019 - New
• Edge Emitting Lasers (EELS) 2019 - New
• Light Shaping Technologies 2019 - New
• Automotive Advanced Front Lighting Systems 2019 - New
• VCSELs - Technology, Industry and MarketTrends 2019 - Update
• IR LEDs and Laser Diodes – Technology,Applications,
and Industry Trends 2018
• Automotive Lighting 2018:Technology, Industry and MarketTrends
• UV LEDs - Technology, Manufacturing and ApplicationTrends 2018
• LiFi:Technology, Industry and MarketTrends 2018
o STRUCTURE, PROCESS  COST REPORT
• VCSEL Comparison 2019
o PATENT REPORT
• VCSELs 2018
DISPLAY
o MARKET ANDTECHNOLOGY REPORT
• Next Generation 3D Display 2019 - New
• Next Generation Human Machine Interaction (HMI)in Displays 2019 - New
• Micro-and Mini-LED Displays 2019 - Update
• QD and Wide Color gamut (WCG)
Display Technologies 2019 - Update
• Displays  OpticalVision Systems forVR,AR  MR 2018
o PATENT REPORT
• MicroLED Displays : Intellectual Property Landscape 2018
Update : 2018 version still available
15©2019 | www.yole.fr | About Yole Développement
OUR 2019 REPORTS COLLECTION (5/5)
18 fields of excellence combined with six markets to provide a complete picture of your industry landscape
POWER ELECTRONICS
o MARKET ANDTECHNOLOGY REPORT
• Power SiC: Materials, Devices and Applications 2019 - Update
• Power Electronics for EV/HEV and e-mobility:
Market, Innovations and Trends 2019 - Update
• Status of the Power Electronics Industry 2019 - Update
• Discrete Power Packaging : Material Market
and Technology Trends 2019 - New
• Status of the Power ICs Industry 2019 - Update
• Status of the Passive Components for the Power Electronics
Industry 2019 - Update
• Status of the Inverter Industry 2019 - Update
• Status of the Power Module Packaging Industry 2019 - Update
• Wireless Charging Market Expectations
and Technology Trends 2018
• Power GaN 2018: Epitaxy, Devices,Applications
and Technology Trends
o STRUCTURE, PROCESS  COST REPORT
• Automotive Power Module Packaging Comparison 2018
• GaN-on-Silicon Transistor Comparison 2019
• SiC Transistor Comparison 2019
o PATENT REPORT
• Power SiC : Materials, Devices and Modules 2019 - New
• Power GaN : Materials, Devices and Modules 2019 – Update
BATTERY  ENERGY MANAGEMENT
o MARKET ANDTECHNOLOGY REPORT
• Status of the Rechargeable Li-ion Battery Industry 2019 - New
• Li-ion Battery Packs for Automotive and Stationary Storage
Applications 2019 - Update
o PATENT REPORT
• Battery Energy Density Increase: Materials
and EmergingTechnologies 2019 - New
• Solid-State Batteries 2019 - New
• Status of the Battery Patents 2018
COMPOUND SEMI.
o MARKET ANDTECHNOLOGY REPORT
• Emerging Compound Semiconductor
Market  Technology Trends 2019 - New
• Status of the Compound Semiconductor Industry 2019 - New
• InP Materials, Devices and Applications 2019 - New
• GaAsWafer and Epiwafer Market: RF, Photonics,
LED and PV Applications 2018
o PATENT REPORT
• GaN-on-Silicon Substrate: Materials, Devices
and Applications 2019 - Update
Update : 2018 version still available
16©2019 | www.yole.fr | About Yole Développement
OUR 2019 MONITORS COLLECTION (1/2)
Get the most updated overview of your market to monitor your strategy
Yole Développement, System Plus Consulting and KnowMade, all part of the Yole Group of Companies, are launching a collection of 10 monitors in 2019. The monitors aim to
provide updated market, technology and patent data as well dedicated quarterly analyses of the evolution in your industry over the previous 12 months. Furthermore, you can
benefit from direct access to the analyst for an on-demand QA and discussion session regarding trend analyses, forecasts and breaking news.
Topics covered will be compact camera modules (CCMs), advanced packaging, compound semiconductors, microfluidics, batteries, RF and memory.
MARKET MONITOR byYole Développement
A FULL PACKAGE:
The monitors will provide the evolution of the market in units, wafer area and revenues.
They will also offer insights into what is driving the business and a close look at what is
happening will also be covered in it.
The following deliverables will be included in the monitors:
• An Excel database with all historical and forecast data
• A PDF slide deck with graphs and comments/analyses covering the expected
evolutions
o ADVANCED PACKAGING – NEW
This monitor will provide the evolution of the advanced packaging platforms. It will
cover Fan-Out Wafer Level Packaging (WLP), Fan-Out Panel Level Packaging (PLP),
Wafer-Level Chip Scale Packaging (WLCSP), Flip Chip packaging platforms, and 2.5D
and 3D Through Silicon Via (TSV) integration. Frequency: Quarterly, starting from Q3
2019
o COMPOUND SEMI. – NEW
This monitor will describe how the compound semiconductor industry is evolving. It
will offer a close look at GaAs, InP, SiC, GaN and other compounds of interest
providing wafer volumes, revenues, application breakdowns and momentum.
Frequency: Quarterly, starting from Q3 2019
o CAMERA MODULE – NEW
This monitor will provide the evolution of the imaging industry, with a close look at
image sensor, camera module, lens and VCM. Volumes, revenues and momentum of
companies like Sony, Samsung, Omnivision and OnSemi will thus be analysed.
Frequency: Quarterly, starting from Q3 2019
o MEMORY – UPDATE
For the memory industry you can have access to a quaterly monitor, as well as an
additional service, a monthly pricing. Both services can be bought seprately:
• DRAM Service: Including a quarterly monitor and monthly pricing.
• NAND Service: Including a quarterly monitor and monthly pricing.
REVERSETECHNOLOGY MONITOR by System Plus Consulting
o SMARTPHONES – NEW
To stay updated on the latest components, packaging and silicon chip choices of the smartphone makers, System Plus Consulting has created its first Smartphone Reverse
Technology monitor. This year, get access to the packaging and silicon content database of at least 20 different flagship smartphones – more than five per quarter. Starting at the
beginning of 2019, the monitor will include an Excel database report for each phone and a quarterly comparison.
17©2019 | www.yole.fr | About Yole Développement
OUR 2019 MONITORS COLLECTION (2/2)
Get the most updated overview of your market to monitor your strategy
PATENT MONITOR by KnowMade
A FULL PACKAGE:
Starting at the beginning of the year, the KnowMade monitors include the following
deliverables:
• An Excel file including the monthly IP database of:
• New patent applications
• Newly granted patents
• Expired or abandoned patents
• Transfer of IP rights through re-assignment and licensing
• Patent litigation and opposition
• Quarterly report including a PDF slide deck with the key facts  figures of the
quarter: IP trends over the three last months, with a close look to key IP players and
key patented technologies.
o GaN for Power  RF Electronics
Wafers and epiwafers, GaN-on-SiC, silicon, sapphire or diamond, semiconductor
devices such as transistors, and diodes, devices and applications including converters,
rectifiers, switches, amplifiers, filters, and Monolothic Microwave Integrated Circuits
(MMICs), packaging, modules and systems.
o GaN for Optoelectronics  Photonics
Wafers and epiwafers, GaN-on-sapphire, SiC or silicon; semiconductor devices such
as LEDs and lasers; and applications including lighting, display, visible communication,
photonics, packaging, modules and systems.
o Li-ion Batteries
Anodes made of lithium metal, silicon, and lithium titanate (LTO); cathodes made of
Lithium Iron Phosphate (LFP), Nickel-Manganese-Cobalt (NMC), Lithium Nickel
Cobalt Aluminium Oxide (NCA), Lithium Nickel Metal Dioxide (LiNiMO2), Lithium
Metal Phosphate (LiMPO4), and Lithium Metal Tetroxide (LiMO4); electrolytes
including liquid, polymer/gel, and solid inorganics; ceramic and other separators;
battery cells including thin film/microbattery, flexible, cylindrical and prismatic; and
battery packs and systems.
o Post Li-ion Batteries
Battery technologies including redox-flow batteries, sodium-ion, lithiumsulfur, lithium-
air, and magnesium-ion, and their supply chains, including electrodes, electrolytes,
battery cells and battery packs/systems.
o Solid-State Batteries
Supply chain including electrodes, battery cells, battery packs/systems and
electrolytes, including polymer, inorganic and inorganic/polymer, inorganic materials,
including argyrodites, LIthium Super Ionic CONductor, (LISICONs), Thio-LISICONs,
sulfide glasses, oxide glasses, perovskites, anti-perovskites and garnets.
o RF Acoustic Wave Filters
Including Surface Acoustic Wave (SAW), Temperature Compensated (TC)- SAW, Bulk
Acoustic Wave- Free-standing Bulk Acoustic Resonator (BAWFBAR), BAW-Solidly-
Mounted Resonator (BAW-SMR), and Packaging.
o RF Power Amplifiers
Including Low Noise Amplifiers, Doherty Amplifiers, Packaging, and Millimeter-Wave
technology.
o RF Front-End Modules
o Microfluidics
From components to chips and systems, including all applications.
18©2019 | www.yole.fr | About Yole Développement
MICRONEWS MEDIA
o About Micronews Media
To meet the growing demand for market,
technological and business information,
Micronews Media integrates several tools able
to reach each individual contact within its
network.We will ensure you benefit from this.
ONLINE ONSITE INPERSON
@Micronews e-newsletter
i-Micronews.com
i-Micronewsjp.com
FreeFullPDF.com
Events Webcasts
Unique, cost-effective ways
to reach global audiences.
Online display advertising
campaigns are great strategies
for improving your
product/brand visibility.They
are also an efficient way to
adapt with the demands of the
times and to evolve an effective
marketing plan and strategy.
Brand visibility, networking
opportunities
Today's technology makes it
easy for us to communicate
regularly, quickly, and
inexpensively – but when
understanding each other is
critical, there is no substitute
for meeting in-person. Events
are the best way to exchange
ideas with your customers,
partners, prospects while
increasing your brand/product
visibility.
Targeted audience
involvement equals clear,
concise perception of your
company’s message.
Webcasts are a smart,
innovative way of
communicating to a wider
targeted audience.Webcasts
create very useful, dynamic
reference material for
attendees and also for
absentees, thanks to the
recording technology.
Benefit from the i-Micronews.com
traffic generated by the 11,200+
monthly unique visitors, the
10,500+ weekly readers of
@Micronews e-newsletter
Several key events planned for
2018 on different topics to
attract 120 attendees on average
Gain new leads for your business
from an average of 340
registrants per webcast
Contact: CamilleVeyrier (veyrier@yole.fr), Marketing  Communication Director
19©2019 | www.yole.fr | About Yole Développement
CONTACT INFORMATION
o CONSULTING AND SPECIFICANALYSIS, REPORT
BUSINESS
• North America:
• Steve LaFerriere, Senior Sales Director forWestern US 
Canada
Email: laferriere@yole.fr – + 1 310 600-8267
• Troy Blanchette, Senior Sales Director for Eastern US 
Canada
Email: troy.blanchette@yole.fr – +1 704 859-0453
• Japan  Rest of Asia:
• Takashi Onozawa, General Manager,Asia Business
Development (India  ROA)
Email: onozawa@yole.fr - +81 34405-9204
• Miho Othake, Account Manager (Japan)
Email: ohtake@yole.fr - +81 3 4405 9204
• Itsuyo Oshiba, Account Manager (Korea  Singapore)
Email: oshiba@yole.fr - +81-80-3577-3042
• Greater China: Mavis Wang, Director of Greater China Business
Development
Email: wang@yole.fr - +886 979 336 809
• Europe: Lizzie Levenez, EMEA Business Development Manager
Email: levenez@yole.fr - +49 15 123 544 182
• RoW: Jean-Christophe Eloy, CEO  President,Yole Développement
Email eloy@yole.fr - +33 4 72 83 01 80
o FINANCIAL SERVICES (in partnership withWoodside
Capital Partners)
• Jean-Christophe Eloy, CEO  President
Email: eloy@yole.fr - +33 4 72 83 01 80
• Ivan Donaldson,VP of Financial Market Development
Email: ivan.donaldson@yole.fr - +1 208 850 3914
o CUSTOM PROJECT SERVICES
• Jérome Azémar,Technical Project Development Director
Email: azemar@yole.fr - +33 6 27 68 69 33
o GENERAL
• CamilleVeyrier, Director, Marketing  Communication
Email: veyrier@yole.fr - +33 472 83 01 01
• Sandrine Leroy, Director, Public Relations
Email: leroy@yole.fr - +33 4 72 83 01 89 / +33 6 33 11 61 55
• Email: info@yole.fr - +33 4 72 83 01 80
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Medical Wearables 2019 Report by Yole Developpement

  • 1. From Technologies to Markets @2019 Medical Wearables: Market and Technology Trends 2019 Sample
  • 2. 2 TABLE OF CONTENTS • Executive summary 08 • Context 28 • Definition of medical wearables • A little beat of History • What’s new? • Product launch, collaboration and fundraising • Market forecasts 53 • Global market data and Market forecasts • Market data and forecasts 2017-2024 in $M by segment • Market forecasts by sensor types • Market shares • Market trends 69 • Market drivers, challenges • R&D Development time and investments related • Market segmentation and segment description • Technology requirement/ application • Key players/ segment • Top Medical Devices: how they position themselves? • Technology trends 132 • Technology description of sensors for medical wearables • Sensors • Manufacturing process and material • Roadmaps • Overview on emerging flexible, Stretchable, printed, and hybrid electronics for medical applications. • Supply chain 185 • Ecosystems • Business models and player’s strategy • Supply chain analysis • Regulation, reimbursement aspects • Market access • Technical challenges of fabrication, packaging, and assembly technics • Conclusion 233 • Perspectives • What’s next Medical Wearables: Market & Technology Analysis 2019 | Sample | www.yole.fr | ©2019
  • 3. 3 Biography & contact ABOUT THE AUTHORS Asma Siari As a Technology & Market Analyst, Biotechnologies & Molecular Innovations, Medical Technologies in the Life Sciences & Healthcare division at Yole Développement (Yole), Asma Siari is involved in the development of technology & market reports as well as the production of custom consulting projects. After a Master’s degree in Biotechnologies, Diagnostic Therapeutics & Management, Asma served as Research Assistant at the Moores Cancer Center (San Diego, CA). She is a coauthor in three scientific publications published in the Molecular Cancer Research Journal. Asma Siari is graduated with an Advanced Master’s degree in International Strategy & Marketing BtoB from EM Lyon Business School (France). Email: siari@yole.fr Jérôme Mouly Jerôme Mouly serves as a Senior Technology & Market Analyst & Business Developer specialized in microtechnologies for inkjet & bioMEMS sensors. Since 2000, he has participated in more than 100 marketing and technological analyses for industrial groups, start-ups and institutes. Previously, Jerome was involved in a support action for value creation of smart miniaturized systems research projects at Yole Finance Innovation, part of Yole Développement. Jérôme holds a Master of Physics from the University of Lyon (France). Email: mouly@yole.fr Medical Wearables: Market & Technology Analysis 2019 | Sample | www.yole.fr | ©2019
  • 4. 4 3M,AACTechnologies,Abbott,Alertgy,AliveCor,Amazon,Amphenol,AMS,Analog Devices,Apple,Artefact,Ava, BACtrack, Biogen, Biolinq, Biometrics, Bittium, Bioserenity, Bloomlife, Bonbouton, Capsule, Cardionet, CarePredict, CareWear Corp, CEA Léti, Cefaly Technology, Chrono Therapeutics, Chronolife, Comepa, Covestro, Dakota, Delsys, Dexcom, D Free, Ectosens, Elvie, Empatica, Excelitas Technologies, Exosystems, Feel, Feetme, Fitbit, Food & Drug Administration, GI Logic, Global Kinetics, Glucowise, Google, G-Tech Medical, Halo Neuroscience, Healthcare Origins, Healthwatch, Heimann Sensor, Hexoskin, Hocoma, Honeywell, IBM, IHealth, Imec, Infineon, Insound, iRythm, JRC, Jari Electrode Supply, Johnson & Johnson, Knowles Acoustics, Kolo Medical, Lifesense, Lifewatch, L’Oréal & La Roche-Posay, MC10, Maxim Integrated, Medatec, Medtronic, Merit Sensor, Melexis, Microsoft, Micralyne, Monica Healthcare, Motiv, Murata, Muse, Mymdband, Neofect, Neucognic, NeuroMetrix, Novioscan, Nonin, Novartis, Nuheara, Nuubo, NVK, NXP, Omron, Orpyx, Oska, OSRAM, Oticon, Oura, Pet Pace, Pfizer, Phonak, Philips Healthcare, Philips Innovation Services, Pkvitality, Preventice, Qardiocore, Renesas, Resmed, ReSound GN, Robert Bosch, Roche, Rohm Semiconductor, Senseonics, Sensimed AG, Sentio Solutions, Shade, Silicon Labs, SleepOn, SMI, Somnarus Inc , Sonova, Sonion, Starkey, STMicroelectronics, Sunfriend,TDK,TE Connectivity,TempTraq,Tempdrop,The Electrode Store,Thync, UCB Pharma, Upright,TTPVentus,Valencell,Verily,Vicardio,Vishay,VitalConnect,Vivosens Medical,Voyce,Wellbrain,Whistle,Withings,Wolfson, Xiaomi, ZoLL, …and many more. LIST OF COMPANIES MENTIONED IN THIS REPORT 230+ slides of market and technology analysis Information gathered through direct discussions with players all along the supply chain Medical Wearables: Market & Technology Analysis 2019 | Sample | www.yole.fr | ©2019
  • 5. 5 THE OBJECTIVES OF THE REPORT • Examine medical wearable device market trends, competitive forces and dynamics, and market drivers • Offer an applications overview of medical wearables for diagnostic, therapeutic, and prevention, along with disruptive technologies (products) • Explain which sensors are used in which healthcare applications, and why • Provide an overview of the main players at each level of the supply chain, with market share • Furnish business models and market projections for 2018 – 2024 • Identify promising technologies and booming applications • Deliver an overview of emerging flexible, stretchable, printed, and hybrid electronics for medical applications Medical Wearables: Market & Technology Analysis 2019 | Sample | www.yole.fr | ©2019
  • 6. 6 SCOPE OF THE REPORT (1/3) Medical wearables for patient activity monitoring and smart treatment delivery Medical wearables for people lacking autonomy and requiring assistance and alerts Medical wearables for animals activity monitoring No prosthesis and implants (pacemakers, neuronal implants, retinal implant…) No wellness, fitness devices and geolocation devices (sport smartwatch, wellness wirst worn…) Not included in the report’s scope Medical Wearables: Market & Technology Analysis 2019 | Sample | www.yole.fr | ©2019
  • 7. 7 TIMELINE OF WEARABLES:A LITTLE BIT OF HISTORY Thomas Jefferson: introduced the first pedometer to the US Thomish Meter 2009 2012 1788 1938 2019 Aurex Corp developed the 1st wearables hearing aid Next step: Medical devices more conformable Hearing aid Fitness tracking Philips lifeline Ingestible sensors and wearables devices Activity trackers, wireless enables wearable technology Proteus Digital Health developed an ingestible sensor approved by the FDA in 2012 to improve patients habits … Apple launched the first approved ECG integrated in smartwatch Single function Multi-functions Consumer fitness and sport products enter the market starting with Bluetooth headset 2000 Appel’s ECG Medical-functions Medical Wearables: Market & Technology Analysis 2019 | Sample | www.yole.fr | ©2019
  • 8. 8 WHAT IS A WEARABLE MEDICAL DEVICE Definitions • According to the US Food and Drug Administration (FDA): a medical device is intended by its manufacturer to be used for humans in order to : • Diagnosis, prevention, monitoring, treatment or alleviation of disease. • Diagnosis, monitoring, treatment, alleviation of or compensation for an injury or handicap. • Investigation, replacement or modification of the anatomy or of a physiological process. Can a wearable be a medical device? • A wearable medical device is a device that is autonomous, noninvasive or minimally invasive, and that performs a specific medical function such as health monitoring or prevention over a prolonged period of time which could be long (>6hours) or short time (<1hour) of wearability. • It includes a sensor technology which is able to collect data in a non invasive, reliable way and deliver information about the surroundings in real-time. • The term ‘‘wearable’’ implies that the support environment is either the human body or a piece of clothing. Handheld and portable devices are therefore not strictly speaking wearable, but this distinction is not always clear as it also depends on the conditions of their use. • A medical wearable device, or an accessory to such a device, need to comply with the regulatory framework if it is to be sold or distributed. Wearable medical technologies have emerged as a growing trend, with challenges for regulators Medical Wearables: Market & Technology Analysis 2019 | Sample | www.yole.fr | ©2019
  • 9. 9 MEDICAL WEARABLES BUT FOR WHAT? Information and data value Reduce healthcare cost • Wearables can replace some hospital devices for homecare devices • Daily monitoring of chronic disease • Increased efficiency for doctors to get access to patient data with less administration • Turn hospitals towards urgent cases only Improve patient adherence • Check data and history of medication • Alert/remind patient or family of any risk for non-adherence • Provide safer working conditions and predict employee injuries and fatal accidents because of fatigue or other factors • Develop a business model to improve adherence (through insurance incentives…) Improve healthcare efficiency • Great impact on both doctors and patients, as they can be in constant connectivity. • Improved learning from daily monitoring of patient reaction to treatment • Improve personalized medicine in chronic disease and oncology • Develop machine learning / artificial intelligence Move to preventive medicine • Make wearables devices discreet and easy to use for daily monitoring • Develop incentives to help monitoring vital signs • Connect more data from environment to prevent from events Improve medical research • Use data generated to better understand medicine effects • Use data generated to better prevent events through population categories • Engage pharmaceutical companies in digital clinical trials Medical Wearables: Market & Technology Analysis 2019 | Sample | www.yole.fr | ©2019
  • 10. 10 AN INCREASING NUMBER OF PRODUCTS WILL REACH THE MARKET* * Non exhaustive list of products Medical Wearables: Market & Technology Analysis 2019 | Sample | www.yole.fr | ©2019
  • 11. 11 SENSING TECHNOLOGY:WHAT CAN WE SENSE USING MEDICAL WEARABLES? A wide variety of wearable devices facilitate personalized healthcare Monitoring and tracking of behavioral health brain, nerve activity and stress EEG Diagnosis and monitoring of chronic conditions such as glucose level in blood Continuous monitoring of vital signs such as cardiac arrhythmias and heart rate enables whole health profiling, versus today’s standard of sporadic sampling CGM Heart rate/ECG/optical sensors Capture of local muscle activation for rehabilitation, motion study and tone assessment EMG Superior mechanical coupling to the body , reduces motion artifacts that cause noise Activity tracker Superior thermal and fluidic transport Temperature & galvanic skin response UV sensing on the body to prevent sun damage UV Correction and improvement of hearing function Hearing aids microphones Termophile sensors Accelerometer Gyroscope Pressure sensorsBiochips Micropumps Electrodes Glucose sensors Electrodes Medical Wearables: Market & Technology Analysis 2019 | Sample | www.yole.fr | ©2019
  • 12. 12 AT SYSTEM LEVEL A convergence Consumer electronics companies Medical device companies Consumer healthcare • Good access to consumers (distribution channels) • Well known by consumers • Lack of experience with medical grade systems • Not used to long-term development (including clinical trials) • Experience with medical grade systems • Reliable devices • Lower access to volume market • Low reputation in consumer marketMedical Wearables: Market & Technology Analysis 2019 | Sample | www.yole.fr | ©2019
  • 13. 13 M&A, COLLABORATIONS, FUNDRAISING AND RELEASED PRODUCTS SINCE 2016 Analysis of the strategic moves in the industry • Definition of medical wearables and history • The transition from fitness and sport to medical wearables and identification of new products • Who are the main players and the new entrants developing new medical devices for the market? • What strategic moves are driving the medical wearables market growth? Medical Wearables: Market & Technology Analysis 2019 | Sample | www.yole.fr | ©2019
  • 14. 14 MARKET DATA AND FORECASTS • Market data and forecasts 2018-2024 for per medical wearable systems • Market data and forecasts 2018-2024 for per sensor types • Market share and dynamics per segment for 2018 Medical Wearables: Market & Technology Analysis 2019 | Sample | www.yole.fr | ©2019
  • 15. 15 MARKET TRENDS AND KEY APPLICATIONS • Market segmentation depending on key technological and economical/behavioral criteria • Each segment has its whole chapter with detailed description, market data, key products examples, key players, requirements and market insights. • Development timeline and price analysis of medical wearable devices Medical Wearables: Market & Technology Analysis 2019 | Sample | www.yole.fr | ©2019
  • 16. 16 ANALYSIS OF TECHNOLOGY TRENDS • Description of the technological challenges and technical requirements, focus on sensors technology • Key players developing technologies for medical wearables and technology roadmap, a dedicated chapter describing and analyzing who is developing what • What are the sweet spots for today and tomorrow Medical Wearables: Market & Technology Analysis 2019 | Sample | www.yole.fr | ©2019 • Description of the technological challenges and technical requirements, focus on sensors technology • Key players developing technologies for medical wearables and technology roadmap, a dedicated chapter describing and analyzing who is developing what • What are the sweet spots for today and tomorrow
  • 17. 17 SUPPLY CHAIN ANALYSIS • Detailed supply chain and collaboration examples • Who’s producing in-house, who is outsourcing, for which volumes? • How can companies all along the supply chain make value with medical wearables? • Regulation and market access Medical Wearables: Market & Technology Analysis 2019 | Sample | www.yole.fr | ©2019
  • 18. 18 RELATED REPORTS BioMEMS & Non-Invasive Sensors: Microsystems for Life Sciences & Healthcare 2018 Connected Medical Devices Market and Business Models 2017 Ultrasound SensingTechnologies for Medical, Industrial and Consumer Applications 2018 Medical Wearables: Market & Technology Analysis 2019 | Sample | www.yole.fr | ©2019
  • 19. In today’s wearable technology market, the vast majority of growth has been in consumer sports, fitness, and wellness. However, wearable devices are rapidly expanding for health and medical uses, and are expected to reach a market value of $32B by 2024. Smartphone ubiquity, sensor miniaturization, and ease of integration have increased the number of wearable products on the market, to the point where such products are now achieving performance levels suitable for medical use-cases. But how will medical wearables make patients healthier - and why now? Medical wearables’ purpose is to monitor a patient’s vital signs in order to prevent health issues, as well as contribute to treatment and rehabilitation. Wearable makers face the same challenges long associated with the medical industry - for example, the need for several layers of validation, i.e. a CE mark and FDA approval. However, with the increasing prevalence of chronic diseases like cardiovascular issues and diabetes (approx. 425M diabetics worldwide), medical wearables’ huge upside far outweighs the red tape involved. An increasing number of wearable devices are approaching medical-grade level: for instance, the Ava wristband, Apple watch, Cefaly patch, and Ectosens patch, along with smartwatches from Omron and Verily. But even though these products hold considerable promise as consumer medical wearables, they still must be comfortable and easy to use, with functions serving very different purposes from activity tracking to glucose monitoring, through atrial fibrilation detection. And what about the Apple Watch Series 4 that was supposedly FDA-approved not so long ago: was this a real event? This segues into another important discussion: what to do with the data, who will exploit the data (and how), and for what purpose? This report details these new product launches and describes what is in the pipeline. Yole Développement's (Yole) analysts also explore the medical wearable technologies used across different market segments, highlight the reasons why such technologies are used, and discuss how they could evolve. MEDICAL WEARABLES Market & Technology report - March 2019 New technologies and faster market launches are driving the medical wearables market. REPORT’S KEY FEATURES • Yole Développement's vision and definition of medical wearables • Analysis of market dynamics for human and veterinary monitoring, therapeutics, and prevention • Medical wearables’ technical and economic requirements? • Key challenges at system and sensor level • Market segmentation including main players, product examples, and market share for each segment • Market data and forecasts for the period 2018 - 2024 for systems and sensors • Regulatory, market access, and target customers in the USA, Europe, and China • Technology trends and supply chain, along with business models adopted by this field’s key players OBJECTIVES OF THE REPORT • Examine medical wearable device market trends, competitive forces and dynamics, and market drivers • Offer an applications overview of medical wearables for diagnostic, therapeutic, and prevention, along with disruptive technologies (products) • Explain which sensors are used in which healthcare applications, and why • Provide an overview of the main players at each level of the supply chain, with market share • Furnish business models and market projections for 2018 - 2024 • Identify promising technologies and booming applications • Deliver an overview of emerging flexible, stretchable, printed, and hybrid electronics for medical applications (Yole Développement, March 2019) MEDICAL WEARABLES AND SENSORS ECOSTYSTEM IS MATURING TO SUSTAIN 31% MARKET GROWTH! The overall market for medical wearable devices will grow at a rate of 31% year-over-year, reaching more than $32B in 2024. In the meantime, the global sensor market for medical wearables, including continuous glucose monitoring (CGM), is expected to reach $2.8B in 2024, with a compound annual growth rate (CAGR) of 21.6% from 2018 - 2024. Led by the Apple Watch Series 4, there is increasingly strong interest to add ECG capability in a smartwatch so that doctors and hospitals can get accurate information on a patient’s cardiac status. At sensor level, increasing complexity of medical wearables turns electronic companies to medical grade sensor experts, like AMS, Maxim Integrated or Valencell developing dedicated platforms. It enables an optimized integration (in terms of footprint and power consumption) while reducing development time with the guarantee of measurement accuracy. Timeline of wearables: a little bit of history HOW MEDICAL WEARABLES WILL MAKE PATIENTS HEALTHIER Thomas Jefferson: introduced the first pedometer to the US Thomish Meter 2009 2012 1788 1938 2019 Aurex Corp developed the 1st wearables hearing aid Next step: Medical devices more conformable Hearing aid Fitness tracking Philips lifeline Ingestible sensors and wearables devices Activity trackers, wireless enables wearable technology Proteus Digital Health developed an ingestible sensor approved by the FDA in 2012 to improve patients habits … Apple launched the first approved ECG integrated in smartwatch Single function Multi-functions Consumer fitness and sport products enter the market starting with Bluetooth headset 2000 Appel’s ECG Medical-functions
  • 20. MEDICAL WEARABLES: MARKET AND TECHNOLOGY TRENDS 2019 Medical wearables today - convergence of two worlds (Yole Développement, March 2019) REMAINING CHALLENGES, BUT A MYRIAD OF ADVANCED TECHNOLOGIES ARE UNDER DEVELOPMENT TO SOLVE THE ISSUES Medical wearables are the convergence of two worlds: the world of medical-grade devices and the world of consumer wearables. Medical wearables also feature two major player types: medical device manufacturers willing to reach consumer healthcare with the promise of higher volumes, and consumer device companies willing to reach the high-value healthcare market. Medical wearables development is quickening and competition is intensifying, prompting players to ensure a high level of quality as well as medical-grade accuracy for the generated data. Sensor and electronics manufacturers are facilitating a faster time-to-market via optimized modules that are ready for integration. For example, a photoplethysmogram (PPG) device for heart-rate measurement combines, among other elements, LEDs and a photodiode. The LEDs emit light through the skin to the blood vessels, and the photodiode receives the unabsorbed portion of light. Sensor designers are developing sensor modules that integrate LEDs and photodiode with the right packaging and electronic architecture, ensuring accuracy of measurement with miniaturized, low-power devices. These turnkey solutions contribute to a faster time-to-market for medical wearable makers and help sensor makers move up the value chain with high-value solutions. Ahighlevelofintegrationandlow-powerconsumption are not the only challenges described in this report, which aims to answer the question, “What could be the key enabling technologies for medical wearables?” Readers will also discover how medical wearable players investigate innovative materials and solutions that meet the patient’s requirements for comfort and painless monitoring. Supple, conformable materials using printed electronic technologies should increasingly benefit high-quality measurement and help avoid errors due to patient movement. This report describes the technology trends and roadmaps that promote a better understanding of how the medical wearables industry and its players are answering patient and user requirements while contributing to lower overall healthcare costs. Since 2014, Yole Développement's analysts have identified more than $550M raised by medical device and diagnostic companies, and the pace at which new medical wearable products are being commercialized is accelerating. Moreover, investments in different acquisitions between large diagnostic companies and consumer companies (i.e. Apple acquiring Glimpse, Medtronic acquiring Nutrino,…) amount to an impressive $900M since 2016, further confirming the medical wearable market’s positive dynamic. Pharmaceutical companies are also turning to wearables in order to improve RD through strategic collaborations. For example, Pfizer, UCB Pharma, Apple, J J, and IBM are just some of the companies testing mobile technology for patients with Parkinson’s. As well, smartwatches and wristband generates information for the consumer, with a clear objective to be later prescribed and work with health insurance and doctors. In this context, Yole’s report provides market data and forecasts along with a focus on the emerging business models. Volume Time 1M 10M • From discrete to dedicated platform • Turnkey solution • Time to market optimization for short cycle times Long cycle time Application oriented 'prescribed medical devices' Short cycle time Application oriented 'consumer healthcare' Photo credits: Osram Medical wearables and sensors: 2018 – 2024 market forecast (in B$) (Yole Développement, March 2019) 0 0.5 1 1.5 2 2.5 3 3.5 4 4.5 5 0 5 10 15 20 25 30 35 2018 2019 2020 2021 2022 2023 2024 Veterinary Maternal neonatal care Medical prevention Rehabilitations systems therapeutics Metabolic cardiovascular monitoring Respiratory movement disorder Glucose monitoring drug delivery Sensors for wearables Medical wearables: CAGR2018-2024 : 31% Sensors: CAGR2018-2024 : 21,6%Medicalwearables Sensors Medical wearables segments:
  • 21. MARKET TECHNOLOGY REPORT COMPANIES CITED IN THE REPORT (non exhaustive list) 3M, AAC Technologies, Abbott, Alertgy, AliveCor, Amazon, Amphenol, AMS, Analog Devices , Apple, Artefact, Ava, BACtrack, Biogen, Biolinq, Biometrics, Bittium, Bioserenity, Bloomlife, Bonbouton, Capsule, Cardionet, CarePredict, CareWear Corp, CEA Léti, Cefaly Technology, Chrono Therapeutics, Chronolife, Comepa, Covestro, Dakota, Delsys, Dexcom, D Free, Ectosens, Elvie, Empatica, Excelitas Technologies, Exosystems, Feel, Feetme, Fitbit, Food Drug Administration, GI Logic, Global Kinetics, Glucowise, Google, G-Tech Medical, Halo Neuroscience, Healthcare Origins, Healthwatch, Heimann Sensor, Hexoskin, Hocoma, Honeywell, IBM, IHealth, Imec, Infineon, Insound, iRythm, JRC, Jari Electrode Supply, Johnson Johnson, Knowles Acoustics, Kolo Medical, Lifesense, Lifewatch, L’Oréal La Roche-Posay, MC10, Maxim Integrated, Medatec, Medtronic, Merit Sensor, Melexis, Microsoft, Micralyne, Monica Healthcare, Motiv, Murata, Muse, Mymdband, Neofect, Neucognic, NeuroMetrix, Novioscan, Nonin, Novartis, Nuheara, Nuubo, NVK, NXP, Omron, Orpyx, Oska, OSRAM, Oticon, Oura, Pet Pace, Pfizer, Phonak, Philips Healthcare, Philips Innovation Services, Pkvitality, Preventice, Qardiocore, Renesas, Resmed, ReSound GN, Robert Bosch, Roche, Rohm Semiconductor, Senseonics, Sensimed AG, Sentio Solutions, Shade, Silicon Labs, SleepOn, SMI, Somnarus Inc , Sonova, Sonion, Starkey, STMicroelectronics, Sunfriend, TDK, TE Connectivity, TempTraq, Tempdrop, The Electrode Store, Thync, UCB Pharma, Upright, TTP Ventus, Valencell, Verily, Vicardio, Vishay, VitalConnect, Vivosens Medical, Voyce, Wellbrain, Whistle, Withings, Wolfson, Xiaomi, ZoLL, and many more... Find more details about this report here: RELATED REPORTS Benefit from our Bundle Annual Subscription offers and access our analyses at the best available price and with great advantages • Connected Medical Devices Market and Business Models 2017 • Ultrasound Sensing Technologies for Medical, Industrial and Consumer Applications 2018 Find all our reports on www.i-micronews.com As a Technology Market Analyst, Biotechnologies Molecular Innovations, Medical Technologies in the Life Sciences Healthcare division at Yole Développement (Yole), Asma Siari is involved in the development of technology market reports as well as the production of custom consulting projects. After a Master’s degree in Biotechnologies, Diagnostic Therapeutics Management, Asma served as Research Assistant at the Moores Cancer Center (San Diego, CA). She is a coauthor in three scientific publications published in the Molecular Cancer Research Journal. Asma Siari graduated with an Advanced Master’s degree in International Strategy Marketing BtoB from EM Lyon Business School (France). AUTHORS TABLE OF CONTENTS (complete content on i-Micronews.com) Executive summary 08 Context 28 Definition of medical wearables A little bit of history What’s new? Product launches, collaborations, and fundraising Market forecasts 53 Global market data and market forecasts Market data and forecasts 2018-2024 in $M, by segment Market forecasts, by sensor type Market share Market trends 69 Market drivers and challenges RD development time, and related investments Market segmentation and segment description Technology requirements/application Key players/segment Top medical devices: how do they position themselves? Technology trends Technological description of sensors for medical wearables Sensors Manufacturing process and materials Roadmaps Overview of emerging flexible, stretchable, printed, and hybrid electronics for medical applications Technology trends 132 Technological description of sensors for medical wearables Sensors Manufacturing process and materials Roadmaps Overview of emerging flexible, stretchable, printed, and hybrid electronics for medical applications Supply chain 185 Ecosystems Business models and players’ strategy Supply chain analysis Regulation and reimbursement aspects Market access Technical challenges regarding fabrication, packaging, and assembly techniques Conclusion Perspectives What’s next Conclusion 233 Jérôme Mouly serves as a Senior Technology Market Analyst Business Developer specialized in microtechnologies for inkjet bioMEMS sensors at Yole Développement (Yole). Jérôme is supporting the development of strategic projects, following leading customers of the company, within the Life Sciences Healthcare division. Since 2000, he is also engaged in more than 100 marketing and technological analyses for industrial groups, start-ups and institutes related to semiconductor medical technologies industry, in the field of inkjet functional printing, wearable sensors and connected medical devices. Jérôme is also regularly involved in international conferences, giving presentations and delivering keynotes. Jérôme Mouly holds a Master of Physics from the University of Lyon (France).
  • 22. ORDER FORM Medical Wearables: Market and Technology Trends 2019 SHIPPING CONTACT First Name: Email: Last Name: Phone: PAYMENT BY CREDIT CARD Visa Mastercard Amex Name of the Card Holder: Credit Card Number: Card Verification Value (3 digits except AMEX: 4 digits): Expiration date: BY BANK TRANSFER BANK INFO: HSBC, 1 place de la Bourse, F-69002 Lyon, France, Bank code: 30056, Branch code: 00170 Account No: 0170 200 1565  87, SWIFT or BIC code: CCFRFRPP, IBAN: FR76 3005 6001 7001 7020 0156 587 RETURN ORDER BY • MAIL: YOLE DÉVELOPPEMENT, Le Quartz, 75 Cours Emile Zola, 69100 Villeurbanne/Lyon - France SALES CONTACTS • Western US Canada - Steve Laferriere: + 1 310 600-8267 – laferriere@yole.fr • Eastern US Canada - Troy Blanchette: +1 704 859 0453 – troy.blanchette@yole.fr • Europe RoW - Lizzie Levenez: + 49 15 123 544 182 – levenez@yole.fr • Japan Rest of Asia - Takashi Onozawa: +81-80-4371-4887 – onozawa@yole.fr • Greater China - Mavis Wang: +886 979 336 809 – wang@yole.fr • Specific inquiries: +33 472 830 180 – info@yole.fr (1) Our Terms and Conditions of Sale are available at www.yole.fr/Terms_and_Conditions_of_Sale.aspx The present document is valid 24 months after its publishing date: March 14, 2019 / ABOUT YOLE DEVELOPPEMENT BILL TO Name (Mr/Ms/Dr/Pr): Job Title: Company: Address: City: State: Postcode/Zip: Country*: *VAT ID Number for EU members: Tel: Email: Date: PRODUCT ORDER - Ref YD19008 Please enter my order for above named report: One user license*: Euro 5,990 Multi user license: Euro 6,490 - The report will be ready for delivery from March 29, 2019 - For price in dollars, please use the day’s exchange rate. All reports are delivered electronically at payment reception. For French customers, add 20% for VAT I hereby accept Yole Développement’s Terms and Conditions of Sale(1) Signature: *One user license means only one person at the company can use the report. Founded in 1998, Yole Développement has grown to become a group of companies providing marketing, technology and strategy consulting, media and corporate finance services, reverse engineering and reverse costing services and well as IP and patent analysis. With a strong focus on emerging applications using silicon and/or micro manufacturing, the Yole group of companies has expanded to include more than 80 collaborators worldwide covering MEMS and Image Sensors, Compound Semiconductors, RF Electronics, Solid-State Lighting, Displays, Software, Optoelectronics, Microfluidics Medical, Advanced Packaging, Manufacturing, Nanomaterials, Power Electronics and Batteries Energy Management. The “More than Moore” market research, technology and strategy consulting company Yole Développement, along with its partners System Plus Consulting, PISEO and KnowMade, support industrial companies, investors and RD organizations worldwide to help them understand markets and follow technology trends to grow their business. CONSULTING AND ANALYSIS • Market data research, marketing analysis • Technology analysis • Strategy consulting • Reverse engineering costing • Patent analysis • Design and characterization of innovative optical systems • Financial services (due diligence, MA with our partner) More information on www.yole.fr MEDIA EVENTS • i-Micronews.com website related @Micronews e-newsletter • Communication webcast services • Events: TechDays, forums… More information on www.i-Micronews.com REPORTS • Market technology reports • Patent investigation and patent infringement risk analysis • Structure, process and cost analysis • Cost simulation tool More information on www.i-micronews.com/reports CONTACTS For more information about : • Consulting Financial Services: Jean-Christophe Eloy (eloy@yole.fr) • Reports: David Jourdan (jourdan@yole.fr) Yole Group of Companies • Press Relations Corporate Communication: Sandrine Leroy (leroy@yole.fr)
  • 23. ORDER FORM Medical Wearables: Market and Technology Trends 2019 SHIPPING CONTACT First Name: Email: Last Name: Phone: PAYMENT BY CREDIT CARD Visa Mastercard Amex Name of the Card Holder: Credit Card Number: Card Verification Value (3 digits except AMEX: 4 digits): Expiration date: BY BANK TRANSFER BANK INFO: HSBC, 1 place de la Bourse, F-69002 Lyon, France, Bank code: 30056, Branch code: 00170 Account No: 0170 200 1565  87, SWIFT or BIC code: CCFRFRPP, IBAN: FR76 3005 6001 7001 7020 0156 587 RETURN ORDER BY • MAIL: YOLE DÉVELOPPEMENT, Le Quartz, 75 Cours Emile Zola, 69100 Villeurbanne/Lyon - France SALES CONTACTS • Western US Canada - Steve Laferriere: + 1 310 600-8267 – laferriere@yole.fr • Eastern US Canada - Troy Blanchette: +1 704 859 0453 – troy.blanchette@yole.fr • Europe RoW - Lizzie Levenez: + 49 15 123 544 182 – levenez@yole.fr • Japan Rest of Asia - Takashi Onozawa: +81-80-4371-4887 – onozawa@yole.fr • Greater China - Mavis Wang: +886 979 336 809 – wang@yole.fr • Specific inquiries: +33 472 830 180 – info@yole.fr (1) Our Terms and Conditions of Sale are available at www.yole.fr/Terms_and_Conditions_of_Sale.aspx The present document is valid 24 months after its publishing date: March 14, 2019 / ABOUT YOLE DEVELOPPEMENT BILL TO Name (Mr/Ms/Dr/Pr): Job Title: Company: Address: City: State: Postcode/Zip: Country*: *VAT ID Number for EU members: Tel: Email: Date: PRODUCT ORDER - Ref YD19008 Please enter my order for above named report: One user license*: Euro 5,990 Multi user license: Euro 6,490 - The report will be ready for delivery from March 29, 2019 - For price in dollars, please use the day’s exchange rate. All reports are delivered electronically at payment reception. For French customers, add 20% for VAT I hereby accept Yole Développement’s Terms and Conditions of Sale(1) Signature: *One user license means only one person at the company can use the report. Founded in 1998, Yole Développement has grown to become a group of companies providing marketing, technology and strategy consulting, media and corporate finance services, reverse engineering and reverse costing services and well as IP and patent analysis. With a strong focus on emerging applications using silicon and/or micro manufacturing, the Yole group of companies has expanded to include more than 80 collaborators worldwide covering MEMS and Image Sensors, Compound Semiconductors, RF Electronics, Solid-State Lighting, Displays, Software, Optoelectronics, Microfluidics Medical, Advanced Packaging, Manufacturing, Nanomaterials, Power Electronics and Batteries Energy Management. The “More than Moore” market research, technology and strategy consulting company Yole Développement, along with its partners System Plus Consulting, PISEO and KnowMade, support industrial companies, investors and RD organizations worldwide to help them understand markets and follow technology trends to grow their business. CONSULTING AND ANALYSIS • Market data research, marketing analysis • Technology analysis • Strategy consulting • Reverse engineering costing • Patent analysis • Design and characterization of innovative optical systems • Financial services (due diligence, MA with our partner) More information on www.yole.fr MEDIA EVENTS • i-Micronews.com website related @Micronews e-newsletter • Communication webcast services • Events: TechDays, forums… More information on www.i-Micronews.com REPORTS • Market technology reports • Patent investigation and patent infringement risk analysis • Structure, process and cost analysis • Cost simulation tool More information on www.i-micronews.com/reports CONTACTS For more information about : • Consulting Financial Services: Jean-Christophe Eloy (eloy@yole.fr) • Reports: David Jourdan (jourdan@yole.fr) Yole Group of Companies • Press Relations Corporate Communication: Sandrine Leroy (leroy@yole.fr)
  • 24. © 2019 Yole Développement FromTechnologies to Market Source: Wikimedia Commons
  • 25. 2©2019 | www.yole.fr | About Yole Développement YOLE DEVELOPPEMENT – FIELDS OF EXPERTISE Life Sciences Healthcare o Microfluidics o BioMEMS Medical Microsystems o Inkjet and accurate dispensing o Solid-State Medical Imaging BioPhotonics o BioTechnologies Power Wireless o RF Devices Technologies o Compound Semiconductors Emerging Materials o Power Electronics o Batteries Energy Management Semiconductor Software o Package,Assembly Substrates o Semiconductor Manufacturing o Memory o Software Computing Photonics, Sensing Display o Solid-State Lighting o Display o MEMS, Sensors Actuators o Imaging o Photonics Optoelectronics Semiconductor Software Power Wireless Photonics, Sensing Display Life Sciences Healthcare
  • 26. 3©2019 | www.yole.fr | About Yole Développement 4 BUSINESS MODELS o Consulting and Analysis • Market data research, marketing analysis • Technology analysis • Strategy consulting • Reverse engineering costing • Patent analysis • Design and characterization of innovative optical systems • Financial services (due diligence, MA with our partner) www.yole.fr o Syndicated reports • Market technology reports • Patent investigation and patent infringement risk analysis • Teardowns reverse costing analysis • Cost simulation tool www.i-Micronews.com/reports o Media • i-Micronews.com website • @Micronews e-newsletter • Communication webcast services • Events:TechDays, forums,… www.i-Micronews.com o Monitors • Monthly and/or Quarterly update • Excel database covering supply, demand, and technology • Price, market, demand and production forecasts • Supplier market shares www.i-Micronews.com/reports
  • 27. 4©2019 | www.yole.fr | About Yole Développement 6 COMPANIES TO SERVEYOUR BUSINESS Due diligence www.yole.fr Manufacturing costs analysis Teardown and reverse engineering Cost simulation tools www.systemplus.fr Market, technology and strategy consulting www.yole.fr IP analysis Patent assessment www.knowmade.fr Innovation and business maker www.bmorpho.com Design and characterization of innovative optical systems www.piseo.fr Yole Group of Companies
  • 28. 5©2019 | www.yole.fr | About Yole Développement OUR GLOBAL ACTIVITY 30%of our business 40%of our business 30%of our business Greater China office Yole Japan HQ in Lyon Nantes Paris Nice Vénissieux Europe office Frankfurt Hsinchu Tokyo Yole Inc. Phoenix Yole Korea Seoul Palo Alto
  • 29. 6©2019 | www.yole.fr | About Yole Développement ANALYSIS SERVICES - CONTENT COMPARISON Technology and Market Report Leadership Meeting QA Service Depth of the analysis Breadthoftheanalysis Meet the Analyst Custom Analysis High High Low
  • 30. 7©2019 | www.yole.fr | About Yole Développement SERVING THE ENTIRE SUPPLY CHAIN Our analysts provide market analysis, technology evaluation, and business plans along the entire supply chain Integrators, end- users and software developers Device manufacturers Suppliers: material, equipment, OSAT, foundries… Financial investors, RD centers
  • 31. 8©2019 | www.yole.fr | About Yole Développement SERVING MULTIPLE INDUSTRIAL FIELDS We work across multiples industries to understand the impact of More-than- Moore technologies from device to system From A to Z… Transportation makers Mobile phone and consumer electronics Automotive Medical systems Industrial and defense Energy management
  • 32. 9©2019 | www.yole.fr | About Yole Développement o Over the course of more than 20 years, Yole Développement has grown to become a group of companies. Together with System Plus Consulting and KnowMade, we now provide marketing, technology and strategy consulting, media and corporate finance services, reverse costing, structure, process and cost analysis services and well as intellectual property (IP) and patent analysis. Together, our group of companies is collaborating ever closer and therefore will offer, in 2019, a collection of over 125 reports and 10 new monitors. Combining respective expertise and methodologies from the three companies, they cover: o If you are looking for: • An analysis of your product market and technology • A review of how your competitors are evolving • An understanding of your manufacturing and production costs • An understanding of your industry’s technology roadmap and related IPs • A clear view supply chain evolution Our reports and monitors are for you! o Our team of over 70 analysts, including PhD and MBA qualified industry veterans from Yole Développement, System Plus Consulting and KnowMade, collect information, identify trends, challenges, emerging markets, and competitive environments. They turn that information into results and give you a complete picture of your industry’s landscape. In the past 20 years, we have worked on more than 2,000 projects, interacting with technology professionals and high-level opinion makers from the main players of their industries and realized more than 5,000 interviews per year. WHAT TO EXPECT IN 2019? In 2019 we will extend our offering with a new ‘monitor’ product which provides more updates on your industry during the year. The Yole Group of Companies is also building on and expanding its investigations of the memory industry. Moreover, in parallel, the Yole Group reaffirms its commitment to a new collection of reports mixing software and hardware and is increasing its involvement in displays, radio-frequency (RF) technology, advanced substrates, batteries and compound semiconductors. Discover our 2019 program right now, and ensure you get a true vision of the industry. Stay tuned! REPORTS COLLECTION www.i-Micronews.com • MEMS Sensors • RF devices technologies • Medical technologies • Semiconductor Manufacturing • Advanced packaging • Memory • Batteries and energy management • Power electronics • Compound semiconductors • Solid state lighting • Displays • Software • Imaging • Photonics
  • 33. 10©2019 | www.yole.fr | About Yole Développement OUR 2019 REPORTS COLLECTION (1/4) 18 fields of excellence combined with six markets to provide a complete picture of your industry landscape Market –Technology – Strategy – byYole Développement Yole Développement (Yole) offers market reports including quantitative market forecasts, technology trends, company strategy evaluation and indepth application analyses. Yole will publish more than 55 reports in 2019, with our partner PISEO contributing to some of the lighting reports. Reverse Costing® – Structure, Process and Cost Analysis – by System Plus Consulting The Reverse Costing® report developed by System Plus Consulting provides full teardowns, including detailed photos, precise measurements, material analyses, manufacturing process flows, supply chain evaluations, manufacturing cost analyses and selling price estimations. The reports listed below are comparisons of several analyzed components from System Plus Consulting. More reports are however available, and over 60 reports will be released in 2019.The complete list is available at www.systemplus.fr. Patent Reports – by KnowMade More than describing the status of the IP situation, these analyses provide a missing link between patented technologies and market, technological and business trends. They offer an understanding of the competitive landscape and technology developments from a patent perspective. They include key insights into key IP players, key patents and future technology trends. For 2019 KnowMade will release over 15 reports. The markets targeted are : • Mobile Consumer • Automotive Transportation • Medical • Industrial • Telecom Infrastructure • Defense Aerospace • Linked reports are dealing with the same topic to provide • a more detailed analysis.
  • 34. 11©2019 | www.yole.fr | About Yole Développement OUR 2019 REPORTS COLLECTION (1/5) 18 fields of excellence combined with six markets to provide a complete picture of your industry landscape MEMS SENSORS o MARKET ANDTECHNOLOGY REPORT • Status of the MEMS Industry 2019 - Update • Status of the Audio Industry 2019 - New • Uncooled Infrared Imagers and Detectors 2019 – Update • Consumer Biometrics:Technologies and MarketTrends 2018 • MEMS Pressure Sensor Market and Technologies 2018 • Gas Particle Sensors 2018 o STRUCTURE, PROCESS COST REPORT • MEMS Sensors Comparison 2019 • MEMS Pressure Sensor Comparison 2018 • Particle Sensors Comparison 2019 • Miniaturized Gas Sensors Comparison 2018 o PATENT REPORT • MEMS Foundry Business Portfolio 2019 - New • Miniaturized Gas Sensors 2019 - New PHOTONIC AND OPTOELECTRONICS o MARKET ANDTECHNOLOGY REPORT • Photonic Integrated Circuit 2019 - New • LiDARs for Automotive and Industrial Applications 2019 - Update • Silicon Photonics 2018 o PATENT REPORT • Silicon Photonics for Data Centers: Optical Transceiver 2019 - New • LiDAR for Automotive 2018 RF DEVICES ANDTECHNOLOGIES o MARKET ANDTECHNOLOGY REPORT • RF GaN Market:Applications, Players,Technology, and Substrates 2019 - Update • 5G’s Impact on RF Front-End Module and Connectivity for Cell Phones 2019 – Update • 5G Impact on Wireless Infrastructure 2019 • Radar andV2X Market Technology for Automotive 2019 - Update • Advanced RF Antenna Market Technology 2019 - New • RF Standards and Technologies for Connected Objects 2018 o STRUCTURE, PROCESS COST REPORT • RF Front-End Module Comparison 2019 - Update • Automotive Radar RF Chipset Comparison 2018 o PATENT REPORT • Antenna for 5G Wireless Communications 2019 - New • RF Front End Modules for Cellphones 2018 • RF Filter for 5G Wireless Communications: Materials and Technologies 2019 • RF GaN : Materials, Devices and Modules 2018 Update : 2018 version still available
  • 35. 12©2019 | www.yole.fr | About Yole Développement OUR 2019 REPORTS COLLECTION (2/5) 18 fields of excellence combined with six markets to provide a complete picture of your industry landscape IMAGING o MARKET ANDTECHNOLOGY REPORT • Status of the CIS Industry 2019:Technology and Foundry Business - Update • Imaging for Automotive 2019 - Update • NeuromorphicTechnologies for Sensing 2019 - Update • Status of the CCM and WLO Industry 2019 - Update • MachineVision for Industry and Automation 2018 • Sensors for RoboticVehicles 2018 o STRUCTURE, PROCESS COST REPORT • Compact Camera Modules Comparison 2019 • CMOS Image Sensors Comparison 2019 o PATENT REPORT • Facial Gesture Recognition Technlogies in Mobile Devices 2019 - New • Apple iPhone X Proximity Sensor Flood Illuminator 2018 MEDICAL IMAGING AND BIOPHOTONICS o MARKET ANDTECHNOLOGY REPORT • X-Ray Detectors for Medical, Industrial • and Security Applications 2019- New • Microscopy Life Science Cameras: Market and Technology Analysis 2019 • Ultrasound technologies for Medical, Industrial and Consumer Applications 2018 o PATENT REPORT • Optical Coherence Tomography Medical Imaging 2018 MICROFLUIDICS o MARKET ANDTECHNOLOGY REPORT • Status of the Microfluidics Industry 2019 - Update • Next Generation Sequencing DNA Synthesis - Technology, Consumables Manufacturing and MarketTrends 2019 - New • Organ-on-a-Chip Market Technology Landscape 2019 - Update • Point-of-Need Testing Application of MicrofluidicTechnologies 2018 • Liquid Biopsy: from Isolation to Downstream Applications 2018 • Chinese Microfluidics Industry 2018 o PATENT REPORT • Microfluidic ManufacturingTechnologies 2019 – New INKJET AND ACCURATE DISPENSING o MARKET ANDTECHNOLOGY REPORT • Inkjet Printheads - Dispensing Technologies Market Landscape 2019 - Update • Emerging Printing Technologies for Microsystem Manufacturing 2019 - New • Piezoelectric Materials from Bulk to Thin Film 2019 - New • Inkjet Functional and Additive Manufacturing for Electronics 2018 o STRUCTURE, PROCESS COST REPORT • Piezoelectric Materials from Bulk to Thin Film Comparison 2019 Update : 2018 version still available
  • 36. 13©2019 | www.yole.fr | About Yole Développement OUR 2019 REPORTS COLLECTION (3/5) 18 fields of excellence combined with six markets to provide a complete picture of your industry landscape BIOTECHNOLOGIES o MARKET ANDTECHNOLOGY REPORT • CRISPR-Cas9 Technology: From Lab to Industries 2018 o PATENT REPORT • Personalized Medicine 2019 – New BIOMEMS MEDICAL MICROSYSTEMS o MARKET ANDTECHNOLOGY REPORT • Medical Wearables: Market Technology Analysis 2019 - New • Neurotechnologies and Brain Computer Interface 2018 • BioMEMS Non-Invasive Sensors: Microsystems for Life Sciences Healthcare 2018 o PATENT REPORT • 3D Cell Printing 2019 - New • CirculatingTumor Cells Isolation 2019 - New • Nanopore Sequencing 2019 - New SOFTWARE AND COMPUTING o MARKET ANDTECHNOLOGY REPORT • Artificial Intelligence Computing For Automotive 2019 - New • Hardware and Software for Artificial Intelligence (AI) in Consumer Applications 2019 - Update • From Image Processing to Deep Learning 2019 - Update • xPU (Processing Units) for Cryptocurrency, Blockchain, HPC and Gaming 2019 – New MEMORY o MARKET ANDTECHNOLOGY REPORT • Status of the Memory Business 2019 - New • MRAM Technology and Business 2019 - New • Emerging NonVolatile Memory 2018 o STRUCTURE, PROCESS COST REPORT • Memory Comparison 2019 o PATENT REPORT • Magnetoresistive Random-Access Memory (MRAM) 2019 - New • 3D Non-Volatile Memory 2018 ADVANCED PACKAGING o MARKET ANDTECHNOLOGY REPORT • Fan Out PackagingTechnologies and MarketTrends 2019 - Update • 3D TSV Integration and Monolithic Business Update 2019 - Update • Advanced RF SiP for Cellphones 2019 - Update • Status of Advanced Packaging 2019 - Update • Status of Advanced Substrates 2019 - Update • Panel Level PackagingTrends 2019 - Update • System in Package (SiP) Technology and Market Trends 2019 - New • Trends in Automotive Packaging 2018 • Thin-Film Integrated Passive Devices 2018 o STRUCTURE, PROCESS COST REPORT • Advanced RF SiP for Cellphones Comparison 2019 Update : 2018 version still available
  • 37. 14©2019 | www.yole.fr | About Yole Développement OUR 2019 REPORTS COLLECTION (4/5) 18 fields of excellence combined with six markets to provide a complete picture of your industry landscape SEMICONDUCTOR MANUFACTURING o MARKET ANDTECHNOLOGY REPORT • Nano Imprint Lithography 2019 - New • Equipment and Materials for Fan Out Packaging 2019 - Update • Equipment for More than Moore:Thin Film Deposition Etching 2019 - New • Wafer Starts for More Than Moore Applications 2018 • Polymeric Materials atWafer-Level for Advanced Packaging 2018 • Bonding and Lithography Equipment Market for More than Moore Devices 2018 o STRUCTURE, PROCESS COST REPORT • Wafer Bonding Comparison 2018 o PATENT REPORT • Hybrid Bonding for 3D Stack 2019 – New SOLID STATE LIGHTING o MARKET ANDTECHNOLOGY REPORT • Status of the Solid State Light Source Industry 2019 - New • Edge Emitting Lasers (EELS) 2019 - New • Light Shaping Technologies 2019 - New • Automotive Advanced Front Lighting Systems 2019 - New • VCSELs - Technology, Industry and MarketTrends 2019 - Update • IR LEDs and Laser Diodes – Technology,Applications, and Industry Trends 2018 • Automotive Lighting 2018:Technology, Industry and MarketTrends • UV LEDs - Technology, Manufacturing and ApplicationTrends 2018 • LiFi:Technology, Industry and MarketTrends 2018 o STRUCTURE, PROCESS COST REPORT • VCSEL Comparison 2019 o PATENT REPORT • VCSELs 2018 DISPLAY o MARKET ANDTECHNOLOGY REPORT • Next Generation 3D Display 2019 - New • Next Generation Human Machine Interaction (HMI)in Displays 2019 - New • Micro-and Mini-LED Displays 2019 - Update • QD and Wide Color gamut (WCG) Display Technologies 2019 - Update • Displays OpticalVision Systems forVR,AR MR 2018 o PATENT REPORT • MicroLED Displays : Intellectual Property Landscape 2018 Update : 2018 version still available
  • 38. 15©2019 | www.yole.fr | About Yole Développement OUR 2019 REPORTS COLLECTION (5/5) 18 fields of excellence combined with six markets to provide a complete picture of your industry landscape POWER ELECTRONICS o MARKET ANDTECHNOLOGY REPORT • Power SiC: Materials, Devices and Applications 2019 - Update • Power Electronics for EV/HEV and e-mobility: Market, Innovations and Trends 2019 - Update • Status of the Power Electronics Industry 2019 - Update • Discrete Power Packaging : Material Market and Technology Trends 2019 - New • Status of the Power ICs Industry 2019 - Update • Status of the Passive Components for the Power Electronics Industry 2019 - Update • Status of the Inverter Industry 2019 - Update • Status of the Power Module Packaging Industry 2019 - Update • Wireless Charging Market Expectations and Technology Trends 2018 • Power GaN 2018: Epitaxy, Devices,Applications and Technology Trends o STRUCTURE, PROCESS COST REPORT • Automotive Power Module Packaging Comparison 2018 • GaN-on-Silicon Transistor Comparison 2019 • SiC Transistor Comparison 2019 o PATENT REPORT • Power SiC : Materials, Devices and Modules 2019 - New • Power GaN : Materials, Devices and Modules 2019 – Update BATTERY ENERGY MANAGEMENT o MARKET ANDTECHNOLOGY REPORT • Status of the Rechargeable Li-ion Battery Industry 2019 - New • Li-ion Battery Packs for Automotive and Stationary Storage Applications 2019 - Update o PATENT REPORT • Battery Energy Density Increase: Materials and EmergingTechnologies 2019 - New • Solid-State Batteries 2019 - New • Status of the Battery Patents 2018 COMPOUND SEMI. o MARKET ANDTECHNOLOGY REPORT • Emerging Compound Semiconductor Market Technology Trends 2019 - New • Status of the Compound Semiconductor Industry 2019 - New • InP Materials, Devices and Applications 2019 - New • GaAsWafer and Epiwafer Market: RF, Photonics, LED and PV Applications 2018 o PATENT REPORT • GaN-on-Silicon Substrate: Materials, Devices and Applications 2019 - Update Update : 2018 version still available
  • 39. 16©2019 | www.yole.fr | About Yole Développement OUR 2019 MONITORS COLLECTION (1/2) Get the most updated overview of your market to monitor your strategy Yole Développement, System Plus Consulting and KnowMade, all part of the Yole Group of Companies, are launching a collection of 10 monitors in 2019. The monitors aim to provide updated market, technology and patent data as well dedicated quarterly analyses of the evolution in your industry over the previous 12 months. Furthermore, you can benefit from direct access to the analyst for an on-demand QA and discussion session regarding trend analyses, forecasts and breaking news. Topics covered will be compact camera modules (CCMs), advanced packaging, compound semiconductors, microfluidics, batteries, RF and memory. MARKET MONITOR byYole Développement A FULL PACKAGE: The monitors will provide the evolution of the market in units, wafer area and revenues. They will also offer insights into what is driving the business and a close look at what is happening will also be covered in it. The following deliverables will be included in the monitors: • An Excel database with all historical and forecast data • A PDF slide deck with graphs and comments/analyses covering the expected evolutions o ADVANCED PACKAGING – NEW This monitor will provide the evolution of the advanced packaging platforms. It will cover Fan-Out Wafer Level Packaging (WLP), Fan-Out Panel Level Packaging (PLP), Wafer-Level Chip Scale Packaging (WLCSP), Flip Chip packaging platforms, and 2.5D and 3D Through Silicon Via (TSV) integration. Frequency: Quarterly, starting from Q3 2019 o COMPOUND SEMI. – NEW This monitor will describe how the compound semiconductor industry is evolving. It will offer a close look at GaAs, InP, SiC, GaN and other compounds of interest providing wafer volumes, revenues, application breakdowns and momentum. Frequency: Quarterly, starting from Q3 2019 o CAMERA MODULE – NEW This monitor will provide the evolution of the imaging industry, with a close look at image sensor, camera module, lens and VCM. Volumes, revenues and momentum of companies like Sony, Samsung, Omnivision and OnSemi will thus be analysed. Frequency: Quarterly, starting from Q3 2019 o MEMORY – UPDATE For the memory industry you can have access to a quaterly monitor, as well as an additional service, a monthly pricing. Both services can be bought seprately: • DRAM Service: Including a quarterly monitor and monthly pricing. • NAND Service: Including a quarterly monitor and monthly pricing. REVERSETECHNOLOGY MONITOR by System Plus Consulting o SMARTPHONES – NEW To stay updated on the latest components, packaging and silicon chip choices of the smartphone makers, System Plus Consulting has created its first Smartphone Reverse Technology monitor. This year, get access to the packaging and silicon content database of at least 20 different flagship smartphones – more than five per quarter. Starting at the beginning of 2019, the monitor will include an Excel database report for each phone and a quarterly comparison.
  • 40. 17©2019 | www.yole.fr | About Yole Développement OUR 2019 MONITORS COLLECTION (2/2) Get the most updated overview of your market to monitor your strategy PATENT MONITOR by KnowMade A FULL PACKAGE: Starting at the beginning of the year, the KnowMade monitors include the following deliverables: • An Excel file including the monthly IP database of: • New patent applications • Newly granted patents • Expired or abandoned patents • Transfer of IP rights through re-assignment and licensing • Patent litigation and opposition • Quarterly report including a PDF slide deck with the key facts figures of the quarter: IP trends over the three last months, with a close look to key IP players and key patented technologies. o GaN for Power RF Electronics Wafers and epiwafers, GaN-on-SiC, silicon, sapphire or diamond, semiconductor devices such as transistors, and diodes, devices and applications including converters, rectifiers, switches, amplifiers, filters, and Monolothic Microwave Integrated Circuits (MMICs), packaging, modules and systems. o GaN for Optoelectronics Photonics Wafers and epiwafers, GaN-on-sapphire, SiC or silicon; semiconductor devices such as LEDs and lasers; and applications including lighting, display, visible communication, photonics, packaging, modules and systems. o Li-ion Batteries Anodes made of lithium metal, silicon, and lithium titanate (LTO); cathodes made of Lithium Iron Phosphate (LFP), Nickel-Manganese-Cobalt (NMC), Lithium Nickel Cobalt Aluminium Oxide (NCA), Lithium Nickel Metal Dioxide (LiNiMO2), Lithium Metal Phosphate (LiMPO4), and Lithium Metal Tetroxide (LiMO4); electrolytes including liquid, polymer/gel, and solid inorganics; ceramic and other separators; battery cells including thin film/microbattery, flexible, cylindrical and prismatic; and battery packs and systems. o Post Li-ion Batteries Battery technologies including redox-flow batteries, sodium-ion, lithiumsulfur, lithium- air, and magnesium-ion, and their supply chains, including electrodes, electrolytes, battery cells and battery packs/systems. o Solid-State Batteries Supply chain including electrodes, battery cells, battery packs/systems and electrolytes, including polymer, inorganic and inorganic/polymer, inorganic materials, including argyrodites, LIthium Super Ionic CONductor, (LISICONs), Thio-LISICONs, sulfide glasses, oxide glasses, perovskites, anti-perovskites and garnets. o RF Acoustic Wave Filters Including Surface Acoustic Wave (SAW), Temperature Compensated (TC)- SAW, Bulk Acoustic Wave- Free-standing Bulk Acoustic Resonator (BAWFBAR), BAW-Solidly- Mounted Resonator (BAW-SMR), and Packaging. o RF Power Amplifiers Including Low Noise Amplifiers, Doherty Amplifiers, Packaging, and Millimeter-Wave technology. o RF Front-End Modules o Microfluidics From components to chips and systems, including all applications.
  • 41. 18©2019 | www.yole.fr | About Yole Développement MICRONEWS MEDIA o About Micronews Media To meet the growing demand for market, technological and business information, Micronews Media integrates several tools able to reach each individual contact within its network.We will ensure you benefit from this. ONLINE ONSITE INPERSON @Micronews e-newsletter i-Micronews.com i-Micronewsjp.com FreeFullPDF.com Events Webcasts Unique, cost-effective ways to reach global audiences. Online display advertising campaigns are great strategies for improving your product/brand visibility.They are also an efficient way to adapt with the demands of the times and to evolve an effective marketing plan and strategy. Brand visibility, networking opportunities Today's technology makes it easy for us to communicate regularly, quickly, and inexpensively – but when understanding each other is critical, there is no substitute for meeting in-person. Events are the best way to exchange ideas with your customers, partners, prospects while increasing your brand/product visibility. Targeted audience involvement equals clear, concise perception of your company’s message. Webcasts are a smart, innovative way of communicating to a wider targeted audience.Webcasts create very useful, dynamic reference material for attendees and also for absentees, thanks to the recording technology. Benefit from the i-Micronews.com traffic generated by the 11,200+ monthly unique visitors, the 10,500+ weekly readers of @Micronews e-newsletter Several key events planned for 2018 on different topics to attract 120 attendees on average Gain new leads for your business from an average of 340 registrants per webcast Contact: CamilleVeyrier (veyrier@yole.fr), Marketing Communication Director
  • 42. 19©2019 | www.yole.fr | About Yole Développement CONTACT INFORMATION o CONSULTING AND SPECIFICANALYSIS, REPORT BUSINESS • North America: • Steve LaFerriere, Senior Sales Director forWestern US Canada Email: laferriere@yole.fr – + 1 310 600-8267 • Troy Blanchette, Senior Sales Director for Eastern US Canada Email: troy.blanchette@yole.fr – +1 704 859-0453 • Japan Rest of Asia: • Takashi Onozawa, General Manager,Asia Business Development (India ROA) Email: onozawa@yole.fr - +81 34405-9204 • Miho Othake, Account Manager (Japan) Email: ohtake@yole.fr - +81 3 4405 9204 • Itsuyo Oshiba, Account Manager (Korea Singapore) Email: oshiba@yole.fr - +81-80-3577-3042 • Greater China: Mavis Wang, Director of Greater China Business Development Email: wang@yole.fr - +886 979 336 809 • Europe: Lizzie Levenez, EMEA Business Development Manager Email: levenez@yole.fr - +49 15 123 544 182 • RoW: Jean-Christophe Eloy, CEO President,Yole Développement Email eloy@yole.fr - +33 4 72 83 01 80 o FINANCIAL SERVICES (in partnership withWoodside Capital Partners) • Jean-Christophe Eloy, CEO President Email: eloy@yole.fr - +33 4 72 83 01 80 • Ivan Donaldson,VP of Financial Market Development Email: ivan.donaldson@yole.fr - +1 208 850 3914 o CUSTOM PROJECT SERVICES • Jérome Azémar,Technical Project Development Director Email: azemar@yole.fr - +33 6 27 68 69 33 o GENERAL • CamilleVeyrier, Director, Marketing Communication Email: veyrier@yole.fr - +33 472 83 01 01 • Sandrine Leroy, Director, Public Relations Email: leroy@yole.fr - +33 4 72 83 01 89 / +33 6 33 11 61 55 • Email: info@yole.fr - +33 4 72 83 01 80 Follow us on