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AGE RELATED CHANGES ON
RESPIRATORY SYSTEM
DR RANJAN
RESIDENT
GERIATRICS
MMC
Normal Respiratory System
Changes Related to Aging
Anatomical changes of the spine and chest wall
structures
 Calcification of articulating surfaces of ribs &
ossification of cartilage makes the chest wall stiffer
 Vertebrae also affected by loss intervertebral space
they compression of vertebral bodies makes
reduced vertebral height.
 These changes modify shape of thorax and results
in KYPHOSIS & Barrel shaped chest.
CONTD…
SENILE EMPHYSEMA
Alveolar dilatation without any destructive changes to the
alveolar walls
Environmental lung insults accumulate over a life time
affect the alveoli and change their structure
Alveoli lose their recoil and enlarge with age
Normal Respiratory System
Changes Related to Aging
Muscular weakness and atrophy
The muscular weakness that accompanies the
aging process also effects the muscles of the
respiratory system
Diaphragm and other muscles near airway
structures are weakened, decreasing their ability
to keep lung structures fully open and able
perfuse oxygen appropriately
Contd….
Expiration is largely a passive process , while inspiration
is depends on diaphragm
Changes in chest wall lead to increase load on
accessory muscle of respiration
Compared to young adults, healthy older persons have
approximately 25% lower diaphragmatic strength.
Maximal inspiratory pressure in old age is 30% lower
than younger population, so lower MIP associated with
decreased hand grip strength, lower body mass index
and low functional vital capacity
Normal Respiratory System
Changes Related to Aging
Decreased Immune System
Eventually with aging most people experience a
decrease in their body’s immune response
This decrease or weakening of the immune
system puts the elderly at increased risk of
contracting respiratory infections and diseases
LUNG VOLUMES &
CAPACITIES
TOTAL LUNG CAPACITY
RESIDUAL VOLUME
• Residual volume increases with aging
• RV/TLC ratio will be high - called
hyperinflation, seen in COPD & ASTHMA
also.
• Vital capacity decreases with age
SPIROMETRY
• It measures dynamic lung function
• FEV1 (volume of air in litre exhaled 1st sec)
• FVC (maximum amount of air you can forcibly
exhaled from your lungs after full inhalation
• FEV1/FVC <0.65 Indicate airway obstruction in older
Population
RESPIRATORY MECHANICS
V/Q VENTILATION PERFUSION RATIO
• Decreased FEV1/FVC, Increased FRC, Increased RV
will further decrease ventilation, so V/Q RATIO much
low in older population
• With increasing age pulmonary vascular resistance
increased and decreased density of pulmonary
capillaries V/Q decreases
DLCO
DIFFUSION LUNG CAPACITY FOR CARBONMONOXIDE
• Performed using a single breath DLCO technique
• DLCO vary with age, sex, height
• Higher in obese
• Lower in anemia
• DLCO declined 5% for every decade after 40 years
Effects of Respiratory Changes
On The Elderly
 Decreased Oxygen
 All the pulmonary disorders in the aging will
have shortness of breath (SOB) as a primary
symptom.
 SOB causes, limiting a persons ability to
perform simple tasks of daily living without
feeling out of breath and exhausted
 Supplemental oxygen is often prescribed in
efforts to increase blood oxygen levels
Effects of Respiratory Changes
On The Elderly
 Poor Sleep Quality
 Respiratory changes with aging can cause frequent
coughing and SOB, disturb quality & duration of
sleep
Ways To Adapt with
Age-Related Respiratory
Changes
 Avoid smoking and other known respiratory irritants
 Participate in physical exercise to increase lung
function with a physicians guidance20
 Stay active and engaged in your daily life. Being
sedentary increases the risk of respiratory mucus
production, muscle weakness, and lung infections
 Stay Informed – Take time to educate yourself on your
condition and ways to improve or help prevent
furthering your symptoms.
Common Respiratory Illnesses of
The Elderly
 Pneumonia: Inflammatory infection of the lungs that
can be both viral and bacterial
 Bronchitis: Swelling and inflammation of the main air
passages to the lungs. This swelling narrows the
airways, making it harder to breathe and causing other
symptoms
 Atelectasis: Partial collapse of portions of the lung
causing shortness of breath and impairing oxygen
perfusion
Secondary/Abnormal Respiratory
System Changes Related to Aging
 Pulmonary Disorders
 Asthma: Inflammation and narrowing of the
airways causing wheezing, coughing,
shortness of breath, and at times respiratory
distress5
 COPD (Chronic Obstructive Pulmonary
Disorder): Progressive disease that
worsens with time. Similar symptoms with
asthma as well as increased respiratory
mucus production causing increased cough
and airway irritation6
Secondary/Abnormal
RespiratorySystem
Changes Related to Aging
 Pulmonary Hypertension: Changes in arterial
pressure in the pulmonary arteries, making it
difficult for the heart to get blood to the lungs to
receive oxygen, causing shortness of breath7
 Sleep Apnea: Pauses in the breathing cycle during
sleep usually caused
by changes to the respiratory structures of the
throat and larynx8
TAKE HOME MESSAGE
• Elastic recoiling of lung decreases
• Chest wall becomes stiffer with aging
• TLC unchanged
• RV increased
• Vital capacity decreases
• V/Q decreases with aging
• DLCO declined with age
THANK YOU

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Aging changes in respiratory system.pptx

  • 1. AGE RELATED CHANGES ON RESPIRATORY SYSTEM DR RANJAN RESIDENT GERIATRICS MMC
  • 2. Normal Respiratory System Changes Related to Aging Anatomical changes of the spine and chest wall structures  Calcification of articulating surfaces of ribs & ossification of cartilage makes the chest wall stiffer  Vertebrae also affected by loss intervertebral space they compression of vertebral bodies makes reduced vertebral height.  These changes modify shape of thorax and results in KYPHOSIS & Barrel shaped chest.
  • 3. CONTD… SENILE EMPHYSEMA Alveolar dilatation without any destructive changes to the alveolar walls Environmental lung insults accumulate over a life time affect the alveoli and change their structure Alveoli lose their recoil and enlarge with age
  • 4. Normal Respiratory System Changes Related to Aging Muscular weakness and atrophy The muscular weakness that accompanies the aging process also effects the muscles of the respiratory system Diaphragm and other muscles near airway structures are weakened, decreasing their ability to keep lung structures fully open and able perfuse oxygen appropriately
  • 5. Contd…. Expiration is largely a passive process , while inspiration is depends on diaphragm Changes in chest wall lead to increase load on accessory muscle of respiration Compared to young adults, healthy older persons have approximately 25% lower diaphragmatic strength. Maximal inspiratory pressure in old age is 30% lower than younger population, so lower MIP associated with decreased hand grip strength, lower body mass index and low functional vital capacity
  • 6. Normal Respiratory System Changes Related to Aging Decreased Immune System Eventually with aging most people experience a decrease in their body’s immune response This decrease or weakening of the immune system puts the elderly at increased risk of contracting respiratory infections and diseases
  • 9. RESIDUAL VOLUME • Residual volume increases with aging • RV/TLC ratio will be high - called hyperinflation, seen in COPD & ASTHMA also. • Vital capacity decreases with age
  • 10. SPIROMETRY • It measures dynamic lung function • FEV1 (volume of air in litre exhaled 1st sec) • FVC (maximum amount of air you can forcibly exhaled from your lungs after full inhalation • FEV1/FVC <0.65 Indicate airway obstruction in older Population
  • 11. RESPIRATORY MECHANICS V/Q VENTILATION PERFUSION RATIO • Decreased FEV1/FVC, Increased FRC, Increased RV will further decrease ventilation, so V/Q RATIO much low in older population • With increasing age pulmonary vascular resistance increased and decreased density of pulmonary capillaries V/Q decreases
  • 12. DLCO DIFFUSION LUNG CAPACITY FOR CARBONMONOXIDE • Performed using a single breath DLCO technique • DLCO vary with age, sex, height • Higher in obese • Lower in anemia • DLCO declined 5% for every decade after 40 years
  • 13. Effects of Respiratory Changes On The Elderly  Decreased Oxygen  All the pulmonary disorders in the aging will have shortness of breath (SOB) as a primary symptom.  SOB causes, limiting a persons ability to perform simple tasks of daily living without feeling out of breath and exhausted  Supplemental oxygen is often prescribed in efforts to increase blood oxygen levels
  • 14. Effects of Respiratory Changes On The Elderly  Poor Sleep Quality  Respiratory changes with aging can cause frequent coughing and SOB, disturb quality & duration of sleep
  • 15. Ways To Adapt with Age-Related Respiratory Changes  Avoid smoking and other known respiratory irritants  Participate in physical exercise to increase lung function with a physicians guidance20  Stay active and engaged in your daily life. Being sedentary increases the risk of respiratory mucus production, muscle weakness, and lung infections  Stay Informed – Take time to educate yourself on your condition and ways to improve or help prevent furthering your symptoms.
  • 16. Common Respiratory Illnesses of The Elderly  Pneumonia: Inflammatory infection of the lungs that can be both viral and bacterial  Bronchitis: Swelling and inflammation of the main air passages to the lungs. This swelling narrows the airways, making it harder to breathe and causing other symptoms  Atelectasis: Partial collapse of portions of the lung causing shortness of breath and impairing oxygen perfusion
  • 17. Secondary/Abnormal Respiratory System Changes Related to Aging  Pulmonary Disorders  Asthma: Inflammation and narrowing of the airways causing wheezing, coughing, shortness of breath, and at times respiratory distress5  COPD (Chronic Obstructive Pulmonary Disorder): Progressive disease that worsens with time. Similar symptoms with asthma as well as increased respiratory mucus production causing increased cough and airway irritation6
  • 18. Secondary/Abnormal RespiratorySystem Changes Related to Aging  Pulmonary Hypertension: Changes in arterial pressure in the pulmonary arteries, making it difficult for the heart to get blood to the lungs to receive oxygen, causing shortness of breath7  Sleep Apnea: Pauses in the breathing cycle during sleep usually caused by changes to the respiratory structures of the throat and larynx8
  • 19. TAKE HOME MESSAGE • Elastic recoiling of lung decreases • Chest wall becomes stiffer with aging • TLC unchanged • RV increased • Vital capacity decreases • V/Q decreases with aging • DLCO declined with age