3. TITLE
A critical review on microbes-based treatment
strategies for mitigation of toxic pollutants
Microbial bioremediation strategies with
wastewater treatment potentialities – A review
A review on characterization and bioremediation of
pharmaceutical industries’ wastewater
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4. OVERVIEW
During the past few decades, pharmaceutical industries have registered a
quantum jump contributing to high economic growth, but simultaneously it has
also given rise to severe environmental pollution.
Bioremediation using microbes is a better option to mitigate pollutants.
Heavy metal bioremediation from water and soil relies heavily on
microorganisms.
Risk assessment of heavy metals in the environment has been uncovered.
Microbes referred to as the most promising technique for removing toxins from
the environment.
6. INTRODUCTION 6
Environmental pollution is one of the major challenges of today’s civilization
Industrial wastewater presents a potential hazard to the natural water system
This wastewater contains many inorganic and organic matters, which are toxic to
the various life forms of the ecosystem
The increasing pollution load of pollutants from industrial water streams has also
caused great harm to the rivers, posing major health risks on either direct bathing
or drinking in the river water
During the past few decades pharmaceutical industries have registered a quantum
jump. Pharmaceutical industry production includes raw material, antibiotics,
variety of medicines and cosmetic products, which in turn generates the effluent
containing constituents harmful to human and aquatic life
7. INTRODUCTION
Pharmaceutical industry wastewater is small.
It contains a high level of pollutants because of the presence of non-
biodegradable organic matter
such as antibiotics, other prescription drugs, non-prescription drugs,
animal and plant steroids, reproductive hormones, analgesics, lipid
regulators, anti-depressants, cytostatic agents, personal care products,
detergent metabolites, flame retardants, product of oil use and
combustion
Other extensively used chemicals, i.e., spent solvents, reaction residues,
used filter media, etc., heavy metals (such as lead, mercury, cadmium,
nickel, chromium) and other pollutants
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9. OBJECTIVES 9
THE OBJECTIVE OF A
STUDY ON MICROBE-
ASSISTED
BIOREMEDIATION OF
PHARMACEUTICAL WASTE
FROM POLLUTANT
ENVIRONMENTS WOULD
BE TO EVALUATE THE
EFFECTIVENESS OF THIS
APPROACH IN REDUCING
THE LEVELS OF
PHARMACEUTICAL WASTE
IN CONTAMINATED
ENVIRONMENTS.
THE STUDY WOULD AIM
TO INVESTIGATE THE
ABILITY OF MICROBIAL
COMMUNITIES TO BREAK
DOWN AND TRANSFORM
PHARMACEUTICAL
COMPOUNDS INTO LESS
HARMFUL SUBSTANCES
THROUGH NATURAL
BIOLOGICAL PROCESSES.
THE STUDY MAY ALSO
SEEK TO IDENTIFY THE
OPTIMAL CONDITIONS
FOR MICROBIAL
GROWTH AND
ACTIVITY, SUCH AS pH,
TEMPERATURE, AND
NUTRIENT
AVAILABILITY, THAT
CAN ENHANCE THE
EFFECTIVENESS OF
BIOREMEDIATION.
THE OBJECTIVE OF THIS
TYPE OF STUDY WOULD
BE TO PROVIDE
VALUABLE INSIGHTS
INTO THE POTENTIAL OF
MICROBE-ASSISTED
BIOREMEDIATION AS A
SUSTAINABLE AND
EFFECTIVE SOLUTION
FOR THE REMEDIATION
OF PHARMACEUTICAL
WASTE FROM POLLUTED
ENVIRONMENTS.
10. KNOWLEDGE GAP 10
Lack of information on the diversity
of microbial communities involved in
the degradation of pharmaceuticals:
While studies have shown that
microbial communities are effective
in breaking down pharmaceuticals,
little is known about the diversity of
microbial communities involved in
the process
Limited information on the fate and
transport of transformed
pharmaceuticals: While microbial
degradation can transform
pharmaceuticals into less harmful
substances, the fate and transport of
these transformed compounds in the
environment are not well understood.
12. CONCLUSION
In conclusion, microbe-assisted bioremediation is a promising approach for the
treatment of pharmaceutical waste from polluted environments. This process
involves the use of microorganisms to degrade, transform, and remove
pollutants from the environment. Microbes such as bacteria, fungi, and algae
have been shown to effectively degrade various types of pharmaceutical
pollutants, including antibiotics, hormones, and non-steroidal anti-inflammatory
drugs (NSAIDs).
Therefore, further research is needed to optimize the conditions for microbial
growth and activity, identify the most effective microorganisms and microbial
consortia, and develop strategies for scaling up the process to industrial-scale
applications. Overall, microbe-assisted bioremediation has the potential to
provide a sustainable and effective solution for the treatment of pharmaceutical
waste from polluted environments.
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