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AN ASSESSMENT OVERVIEW OF MICROBE
ASSISTED BIOREMEDIATION OF
PHARMACEUTICAL WASTE FROM POLLUTANT
ENVIRONMENT
Hafiz Tahir Mahmood​
Tahir
2220771
CONTENT
 Title
 Overview
 ​Introduction
 Objectives
 ​Knowledge gap
 Results
 Conclusion
TITLE
 A critical review on microbes-based treatment
strategies for mitigation of toxic pollutants
 Microbial bioremediation strategies with
wastewater treatment potentialities – A review
 A review on characterization and bioremediation of
pharmaceutical industries’ wastewater
3
OVERVIEW
 During the past few decades, pharmaceutical industries have registered a
quantum jump contributing to high economic growth, but simultaneously it has
also given rise to severe environmental pollution.
 Bioremediation using microbes is a better option to mitigate pollutants.
 Heavy metal bioremediation from water and soil relies heavily on
microorganisms.
 Risk assessment of heavy metals in the environment has been uncovered.
 Microbes referred to as the most promising technique for removing toxins from
the environment.
GRAPHICAL ABSTRACT
5
INTRODUCTION 6
 Environmental pollution is one of the major challenges of today’s civilization
 Industrial wastewater presents a potential hazard to the natural water system
 This wastewater contains many inorganic and organic matters, which are toxic to
the various life forms of the ecosystem
 The increasing pollution load of pollutants from industrial water streams has also
caused great harm to the rivers, posing major health risks on either direct bathing
or drinking in the river water
 During the past few decades pharmaceutical industries have registered a quantum
jump. Pharmaceutical industry production includes raw material, antibiotics,
variety of medicines and cosmetic products, which in turn generates the effluent
containing constituents harmful to human and aquatic life
INTRODUCTION
 Pharmaceutical industry wastewater is small.
 It contains a high level of pollutants because of the presence of non-
biodegradable organic matter
 such as antibiotics, other prescription drugs, non-prescription drugs,
animal and plant steroids, reproductive hormones, analgesics, lipid
regulators, anti-depressants, cytostatic agents, personal care products,
detergent metabolites, flame retardants, product of oil use and
combustion
 Other extensively used chemicals, i.e., spent solvents, reaction residues,
used filter media, etc., heavy metals (such as lead, mercury, cadmium,
nickel, chromium) and other pollutants
7
8
OBJECTIVES 9
THE OBJECTIVE OF A
STUDY ON MICROBE-
ASSISTED
BIOREMEDIATION OF
PHARMACEUTICAL WASTE
FROM POLLUTANT
ENVIRONMENTS WOULD
BE TO EVALUATE THE
EFFECTIVENESS OF THIS
APPROACH IN REDUCING
THE LEVELS OF
PHARMACEUTICAL WASTE
IN CONTAMINATED
ENVIRONMENTS.
THE STUDY WOULD AIM
TO INVESTIGATE THE
ABILITY OF MICROBIAL
COMMUNITIES TO BREAK
DOWN AND TRANSFORM
PHARMACEUTICAL
COMPOUNDS INTO LESS
HARMFUL SUBSTANCES
THROUGH NATURAL
BIOLOGICAL PROCESSES.
THE STUDY MAY ALSO
SEEK TO IDENTIFY THE
OPTIMAL CONDITIONS
FOR MICROBIAL
GROWTH AND
ACTIVITY, SUCH AS pH,
TEMPERATURE, AND
NUTRIENT
AVAILABILITY, THAT
CAN ENHANCE THE
EFFECTIVENESS OF
BIOREMEDIATION.
THE OBJECTIVE OF THIS
TYPE OF STUDY WOULD
BE TO PROVIDE
VALUABLE INSIGHTS
INTO THE POTENTIAL OF
MICROBE-ASSISTED
BIOREMEDIATION AS A
SUSTAINABLE AND
EFFECTIVE SOLUTION
FOR THE REMEDIATION
OF PHARMACEUTICAL
WASTE FROM POLLUTED
ENVIRONMENTS.
KNOWLEDGE GAP 10
Lack of information on the diversity
of microbial communities involved in
the degradation of pharmaceuticals:
While studies have shown that
microbial communities are effective
in breaking down pharmaceuticals,
little is known about the diversity of
microbial communities involved in
the process
Limited information on the fate and
transport of transformed
pharmaceuticals: While microbial
degradation can transform
pharmaceuticals into less harmful
substances, the fate and transport of
these transformed compounds in the
environment are not well understood.
RESULTS
11
Removal degree by P.
ostreatus of selected
pharmaceuticals from a
medium in the function of
time.
CONCLUSION
 In conclusion, microbe-assisted bioremediation is a promising approach for the
treatment of pharmaceutical waste from polluted environments. This process
involves the use of microorganisms to degrade, transform, and remove
pollutants from the environment. Microbes such as bacteria, fungi, and algae
have been shown to effectively degrade various types of pharmaceutical
pollutants, including antibiotics, hormones, and non-steroidal anti-inflammatory
drugs (NSAIDs).
 Therefore, further research is needed to optimize the conditions for microbial
growth and activity, identify the most effective microorganisms and microbial
consortia, and develop strategies for scaling up the process to industrial-scale
applications. Overall, microbe-assisted bioremediation has the potential to
provide a sustainable and effective solution for the treatment of pharmaceutical
waste from polluted environments.
12
THANK YOU
Hafiz Tahir Mehmood Tahir

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An assessment overview of microbe assisted bioremediation of.pptx

  • 1. AN ASSESSMENT OVERVIEW OF MICROBE ASSISTED BIOREMEDIATION OF PHARMACEUTICAL WASTE FROM POLLUTANT ENVIRONMENT Hafiz Tahir Mahmood​ Tahir 2220771
  • 2. CONTENT  Title  Overview  ​Introduction  Objectives  ​Knowledge gap  Results  Conclusion
  • 3. TITLE  A critical review on microbes-based treatment strategies for mitigation of toxic pollutants  Microbial bioremediation strategies with wastewater treatment potentialities – A review  A review on characterization and bioremediation of pharmaceutical industries’ wastewater 3
  • 4. OVERVIEW  During the past few decades, pharmaceutical industries have registered a quantum jump contributing to high economic growth, but simultaneously it has also given rise to severe environmental pollution.  Bioremediation using microbes is a better option to mitigate pollutants.  Heavy metal bioremediation from water and soil relies heavily on microorganisms.  Risk assessment of heavy metals in the environment has been uncovered.  Microbes referred to as the most promising technique for removing toxins from the environment.
  • 6. INTRODUCTION 6  Environmental pollution is one of the major challenges of today’s civilization  Industrial wastewater presents a potential hazard to the natural water system  This wastewater contains many inorganic and organic matters, which are toxic to the various life forms of the ecosystem  The increasing pollution load of pollutants from industrial water streams has also caused great harm to the rivers, posing major health risks on either direct bathing or drinking in the river water  During the past few decades pharmaceutical industries have registered a quantum jump. Pharmaceutical industry production includes raw material, antibiotics, variety of medicines and cosmetic products, which in turn generates the effluent containing constituents harmful to human and aquatic life
  • 7. INTRODUCTION  Pharmaceutical industry wastewater is small.  It contains a high level of pollutants because of the presence of non- biodegradable organic matter  such as antibiotics, other prescription drugs, non-prescription drugs, animal and plant steroids, reproductive hormones, analgesics, lipid regulators, anti-depressants, cytostatic agents, personal care products, detergent metabolites, flame retardants, product of oil use and combustion  Other extensively used chemicals, i.e., spent solvents, reaction residues, used filter media, etc., heavy metals (such as lead, mercury, cadmium, nickel, chromium) and other pollutants 7
  • 8. 8
  • 9. OBJECTIVES 9 THE OBJECTIVE OF A STUDY ON MICROBE- ASSISTED BIOREMEDIATION OF PHARMACEUTICAL WASTE FROM POLLUTANT ENVIRONMENTS WOULD BE TO EVALUATE THE EFFECTIVENESS OF THIS APPROACH IN REDUCING THE LEVELS OF PHARMACEUTICAL WASTE IN CONTAMINATED ENVIRONMENTS. THE STUDY WOULD AIM TO INVESTIGATE THE ABILITY OF MICROBIAL COMMUNITIES TO BREAK DOWN AND TRANSFORM PHARMACEUTICAL COMPOUNDS INTO LESS HARMFUL SUBSTANCES THROUGH NATURAL BIOLOGICAL PROCESSES. THE STUDY MAY ALSO SEEK TO IDENTIFY THE OPTIMAL CONDITIONS FOR MICROBIAL GROWTH AND ACTIVITY, SUCH AS pH, TEMPERATURE, AND NUTRIENT AVAILABILITY, THAT CAN ENHANCE THE EFFECTIVENESS OF BIOREMEDIATION. THE OBJECTIVE OF THIS TYPE OF STUDY WOULD BE TO PROVIDE VALUABLE INSIGHTS INTO THE POTENTIAL OF MICROBE-ASSISTED BIOREMEDIATION AS A SUSTAINABLE AND EFFECTIVE SOLUTION FOR THE REMEDIATION OF PHARMACEUTICAL WASTE FROM POLLUTED ENVIRONMENTS.
  • 10. KNOWLEDGE GAP 10 Lack of information on the diversity of microbial communities involved in the degradation of pharmaceuticals: While studies have shown that microbial communities are effective in breaking down pharmaceuticals, little is known about the diversity of microbial communities involved in the process Limited information on the fate and transport of transformed pharmaceuticals: While microbial degradation can transform pharmaceuticals into less harmful substances, the fate and transport of these transformed compounds in the environment are not well understood.
  • 11. RESULTS 11 Removal degree by P. ostreatus of selected pharmaceuticals from a medium in the function of time.
  • 12. CONCLUSION  In conclusion, microbe-assisted bioremediation is a promising approach for the treatment of pharmaceutical waste from polluted environments. This process involves the use of microorganisms to degrade, transform, and remove pollutants from the environment. Microbes such as bacteria, fungi, and algae have been shown to effectively degrade various types of pharmaceutical pollutants, including antibiotics, hormones, and non-steroidal anti-inflammatory drugs (NSAIDs).  Therefore, further research is needed to optimize the conditions for microbial growth and activity, identify the most effective microorganisms and microbial consortia, and develop strategies for scaling up the process to industrial-scale applications. Overall, microbe-assisted bioremediation has the potential to provide a sustainable and effective solution for the treatment of pharmaceutical waste from polluted environments. 12
  • 13. THANK YOU Hafiz Tahir Mehmood Tahir