H v mendenhall cv, 4 6-15

H. V. Mendenhall DVM, PhD Curriculum Vitae
As of April 6, 2015
H. VINCE MENDENHALL
Consultant, Preclinical Surgery
EDUCATION:
1981 Ph.D., (Experimental Surgery) Colorado State University
1968 DVM, Colorado State University
PROFESSIONAL EXPERIENCE:
2015-Present Consultant, Preclinical Surgery
 Consults with sponsors on preclinical study designs for necessary
animal studies on newly developed medical devices in all specialties,
performing extensive discovery and developmental work along with
pilot studies to establish a definitive GLP protocol.
 Emphasizes the importance of selection of the correct animal model and
other techniques in order to gain definitive results that are translatable
to the human condition.
 Will accompany the sponsor for necessary FDA panel meetings if so
desired.
 Writes definitive protocols, acts as "on-site Study Director" for the
sponsor, and will actually perform the necessary surgical procedures
and follow up examinations and necropsies and help direct
histopathological and other endpoints, including MRI, CT and microCT
examinations. Writes the final report for the study, suitable for
submission to the FDA.
 Involved in specialized toxicology studies from the standpoint of
targeted drug delivery and specialized pharmacokinetics, i.e., CSF, bile
duct implants for first pass pharmacokinetics, and lymphatic PK.

As of April 6, 2015
2008-2015 Director, Preclinical Translational Services, Wake Forest Innovation
Quarter, Winston-Salem, NC.
 Responsible for offering Industry partners a central contact point for
contract, “fee-for-service”, non-clinical surgical research.
 Responsible to the Wake Forest Innovation Quarter tenants with a
local resource for non-clinical surgical research.
 Responsible for providing Wake Forest University faculty with a
training and internal resource to further their skills in non-clinical
surgical research.
2012-2014 Affiliate Faculty Member of the Center for Biomolecular Imaging, Wake
Forest University, Winston-Salem, NC.
1993-2008 Principal Scientist, Preclinical Surgery, Charles River Laboratories,
Preclinical Services, Shrewsbury, MA.
 Responsible for the overall operation of the Surgical Facility,
including the operating rooms, anesthesia management, analgesia,
fluid therapy, perioperative care and monitoring, radiological
support, and all associated equipment.
 Responsible for the conduct of the surgical portion of any study.
 Responsible for the actual performance of any surgical procedure
that other members of the Department have not been adequately
trained to perform.
 Responsible for training and professional development of
veterinarians and Research Assistants in the performance of routine
surgical procedures, anesthesia and aseptic technique.
 May serve as Study Director on any study in which the surgical
component is a primary part of the Study Design.
 Serve as consultant to all Departments and Laboratories of Charles
River Laboratories, Preclinical Services, for studies that have a
surgical component.
1992-1993 Consultant, Biomedical Surgical Research, Stillwater, MN
 Provided independent contract surgical support for Contract
Laboratories in the performance of their studies that had a surgical
component.

As of April 6, 2015
1982-1991 Senior Surgical Research Specialist, 3M Center, St. Paul, MN
 Was responsible for the overall operation of the Surgical Facility,
including the operating rooms, anesthesia, radiological support, and
all associated equipment.
 Was responsible for the research phases involved in the
development of new surgical devices in the areas of neurology,
orthopedics, cardiovascular, ophthalmic and general abdominal
surgery, as well as in wound healing research.
 Was responsible for the actual performance of any surgical
procedure that other members of the Department have not been
adequately trained to perform.
 Was responsible for training of Surgical Technicians in the
performance of routine surgical procedures, anesthesia and aseptic
technique.
 Served as Study Director on any study that involved the
implantation of a new surgical device.
 Served as a keynote speaker and trainer in the use of marketed
surgical devices to international physicians in 28 countries.
1977-1993 Owner/Operator of Veterinary Surgical Specialists, (Referral Surgery)
 Was responsible for the performance of clinical veterinary cases
requiring complicated and difficult surgery. These procedures were
primarily of an orthopedic nature, although many cases involved
thoracic, abdominal and ophthalmic procedures.
1975-1982 Surgical Research Specialist, 3M Center, St. Paul, MN
 Developed and designed the Surgical Research Facility within 3M
to serve as an internal contract laboratory to all Medical Device
Divisions, including Orthopedics, Dental, Wound Care,
Ophthalmic and Cardiovascular (Sarns), including the operating
rooms, anesthesia, radiological support, and all associated
equipment.
 Was responsible for the research phases involved in the
development of new surgical devices in these Divisions.
 Was responsible for the actual performance of any surgical
procedure that other members of the Department have not been
adequately trained to perform.
 Was responsible for training of Surgical Technicians in the
performance of routine surgical procedures, anesthesia and aseptic
technique.

As of April 6, 2015
 Served as Study Director on any study which involved the
implantation of a new surgical device.
1975-1977 Emergency and Relief General Practitioner, and Referral Surgeon, St.
Paul, MN
 Responsible for the Emergency Care of animals for several private
veterinary clinics in Minneapolis and St. Paul, MN.
 Responsible for the conduct of difficult clinical surgical procedures
on a referral basis from over 100 private veterinary clinics in
Minneapolis and St. Paul, MN.
1974-1975 Staff Vascular Surgeon, Surgical Laboratory, Colorado State University
 Responsible for the actual surgical procedures involved in funded
NIH grants for which there was a vascular surgical component.
1973 Lecturer in Surgical Anatomy, Colorado State University
 Responsible for the preparation and delivery of lectures in the basics
of anatomy as it related to surgical procedures of all types to third
year veterinary students.
1972-1975 Staff Neurosurgeon, Veterinary Teaching Hospital, Colorado State
University
 Responsible for the actual surgical procedures involved in approved
NIH grants for which there was a neurosurgical surgical component.
This work was primarily related to spinal cord injury research.
 Responsible for the surgical correction of any traumatic injury to the
spinal cord of dogs and cats.
1972-1974 Second Assistant in human General, Neuro and Cardiovascular Surgery,
Poudre Valley Memorial Hospital, Fort Collins, Colorado
 Had the OR responsibilities of a second year physician resident in
general, neuro- and cardiovascular surgery.
1971-1975 Graduate Student in Experimental Surgery, Surgical Laboratory,
Colorado State University
 Completed the course work necessary for a PhD in Experimental
Surgery.

As of April 6, 2015
1968-1971 General Veterinary Practice, Assistant Senior Veterinarian and Staff
Surgeon, Rangitaiki Plains Dairy Company, Edgecumbe, New Zealand
 Responsible for the veterinary care of all types of animals, primarily
dairy cows, horses and small animals (dogs and cats).
PROFESSIONAL AFFILIATIONS:
 Society for Biomaterials
 Delta Chapter, Phi Zeta
 Academy of Surgical Research
 Elected member: European Society for Knee Surgery and Arthroscopy
 Who's Who in Frontiers of Science & Technology - 1985
 Who's Who in Veterinary Science & Medicine - 1991-1992
 Who’s Who in Science and Engineering - 1998-1999
 Who’s Who in America – 1999-2003
 Strathmore’s Who’s Who – 1999-2002
 The Lexington Who’s Who Registry – 2000-2002
 Who’s Who in the World – 2001-2003
AWARDS:
 1982 – Outstanding PhD Dissertation - Society of Biomaterials
 2002 Von Recum Award for outstanding contributions to the field of investigative surgical
research and the Academy of Surgical Research.
 President, Academy of Surgical Research, 2004-2005
BOOK CHAPTERS AND MONOGRAPHS:
1. Mendenhall, HV. Evaluation of polypropylene as an artificial anterior cruciate ligament in
dogs, Ph.D. Thesis, Ft. Collins, Colorado, (c) 1981.
2. Mendenhall, HV. Principal considerations for experimental surgical procedures, The
Handbook of Biomaterials Evaluation, MacMillan Publishing Company, 265-275, 1986.
3. Mendenhall, HV. General Surgical Considerations, Handbook of Biomaterials Evaluation,
MacMillan Publishing Company, 251-289, 1986.

As of April 6, 2015
4. Van Kampen, CL, Mendenhall, HV, McPherson, GK. “Synthetic augmentation of
biological anterior cruciate ligament substitutions" in The Anterior, Cruciate Deficient
Knee: New Concepts in Ligament Repair, The C.V. Mosby Co., 1987.
5. Mishra, N, Mendenhall, HV, Willson, J. Guidance Document for the Preparation of
Investigational Device Exemptions and Premarket Approval Applications for Intra-
articular Prosthetic Knee Ligament Devices. U.S. Department of Health and Human
Services, Food and Drug Administration, Center for Devices and Radiological Health,
Rockville, MD 20850, September 1, 1987
6. Mendenhall, HV. Surgical principles of biomaterial implantation, Encyclopedic
Handbook of Biomaterials and Bioengineering, Marcel Dekker, Inc. 1-26, 1995.
7. Mendenhall, HV, Horvath, C, Piechowiak, M, Johnson, L, Bayer, K. An External Thoracic
Duct Venous Shunt to Allow for Long Term Collection of Lymph and Blood in the
Conscious Pig. Advances in Swine in Biomedical Research, vol.2. 621-627, 1996.
8. Mendenhall, HV. Animal Models for Preclinical Testing of Medical Devices.
Biomaterials and Bioengineering Handbook. Ed. Wise DL. Marcel Dekker, Inc. 199-204,
2000.
9. Mendenhall, HV. Animal Selection, Handbook of Biomaterials Evaluation, 2nd Ed. Taylor
& Francis, 475-480, 1999.
10. Mendenhall, HV. Surgical Procedures, Handbook of Biomaterials Evaluation, 2nd Ed.
Taylor & Francis, 481-492, 1999
11. Mendenhall, HV, Cornell, S, Scalaro, M. Surgical Preparation and Infusion of the Large
Primate. In: Handbook of Pre-clinical Continuous Intravenous Infusion, Ed. Healing G.,
Smith D., p161-180. Taylor and Francis, 2000.
REFEREED PUBLICATIONS:
1. Mendenhall, HV, Litwak, P, Yturraspe, DJ, Ingram, JT, Lumb, WV. Aggressive
pharmacologic and surgical treatment of spinal cord injuries in dogs and cats, J Am Vet
Med Assoc, (1976) 168(11), 1026-1031.
2. Kennedy, JC, Roth, JH, Mendenhall, HV, Sanford, JB. Intraarticular replacement in the
anterior cruciate ligament-deficient knee, Am J Sports Med, (1980) 8(1), 1-8.
3. Siegel, LG, Mendenhall, HV, Liston, SL. Christmas bow pins: a potential inhaled foreign
body made safer by industrial modifications, So Med J, (1981) 74(1), 17-20.

As of April 6, 2015
4. Ibid. Today's OR Nurse, (1981) 3(3), 24.
5. Ibid. 1982 Yr Bk of Pediatrics, (1982) Yr Bk Med Pub, Chicago.
6. Mendenhall, HV, McPherson, GK, Gibbons, DF, Plenk, H. Jr., Rottmann, W, Sanford, JB,
Kennedy, JC. Histological and Mechanical Evaluation of the Ligament Augmentation
Device. Trans Am Soc Artif Intern Organs (1983) 29:314-7.
7. McPherson, GK, Mendenhall, HV, Gibbons, DF, Plenk, H, Rottman, W, Sanford, JB,
Kennedy, JC, Roth, JH. Experimental mechanical and histologic evaluation of Kennedy
ligament augmentation device, Clin Ortho Rel Res, (1985) 196, 186-195.
8. Fredell, PA, Solem, LD, Ahrenholz, DH, Bahmet, W, Grussing, DM, Mendenhall, HV,
Erickson, EH, Trancik, RJ. Determination of silver penetration into burn eschar by atomic
absorption, J Burn Care Rehab, (1985) 6(1), 55-57.
9. Mendenhall, HV, Roth, JH, Kennedy, JC, Winter, GD, Lumb, WV. Evaluation of the
polypropylene braid as a prosthetic anterior cruciate ligament replacement in the dog, Am
J Sports Med, (1987) 15(6), 543-546.
10. Jackson, D.W., Grood, E.S., Arnoczky, S.P., Butler, D. L., Simon, T.M., Mendenhall, H.V.
Cruciate reconstruction using freeze dried anterior cruciate ligament allograft and a
ligament augmentation device (LAD): an experimental study in a goat model, Am J of
Sports Med (1987) 15(6), 528-538.
11. Holden, J.P., Grood, E.S., Butler, D.L., Noyes, F.R., Mendenhall, H.V., Van Kampen,
C.L., Neidich, R.L. Biomechanics of fascia lata ligament replacements: early post-
operative changes in the goat, J of Orthopaedic Res 6, 639-647, 1988.
12. Roth, J.H., Mendenhall, H.V., McPherson, G.K. The effect of immobilization on goat
knees following reconstruction of the anterior cruciate ligament, Clinical Orthopaedics
229, 278-282, 1988.
13. Falconer, D.P., Lewis, T.W., Lamprecht, E.G., Mendenhall, H.V. Evaluation of the Unilink
Microvascular Anastomotic Device in the dog, J Reconstructive Microsurgery 6(3), 215-
222, 1990.
14. Tountas, C.P., Bergman, R.A., Lewis, T.W., Stone, H.E., Pyrek, J.D., Mendenhall, H.V. A
comparison of peripheral nerve repair using an absorbable tubulization device and
conventional suture in primates, J of Applied Biomaterials 4, 261-268, 1993.
15. Gibbons, D.F., Mendenhall, H.V., Van Kampen, C.L., Lamprecht, E.G. The effect of
motion on the tissue response to polymeric fiber implants, Clin Mat 15, 37-41, 1994.

As of April 6, 2015
16. Atkinson, TS, Atkinson, PJ, Mendenhall, HV, Haut, RC. Patellar Tendon and Infrapatellar
Fat Pad Healing after harvest of an ACL Graft. J Surg Res, 79(1): 25-30, 1998.
17. Badylak, S., Arnoczky, S., Plouhar, P. Haut, R., Mendenhall, V., Clarke, R., Horvath, C.
Naturally Occurring Extracellular Matrix as a Scaffold for Musculoskeletal Repair.
Clinical Orthopedics and Related Research, 367S, S333-S343, 1999.
18. Chen, SA, Sawchuk, RJ, Brundage, RC, Horvath, C, Mendenhall, HV, Gunther, RA,
Braeckman, RA. Plasma and Lymph Pharmacokinetics of Recombinant Human
Interleukin-2 and Polyethylene Glycol-Modified Interleukin-2 in Pigs. Journal of
Pharmacology and Experimental Therapeutics, 293:248-259, 2000.
19. Qing-Qing Q, Mendenhall, H.V., Garlick, D.S., Connor, J. Evaluation of Bone
Regeneration at Critical-Sized Calvarial Defect by DBM/AM Composite. J Bio Mat Res
Part B: Applied Biomaterials. 81B, Issue 2 (2006), 516-523.
20. Cornacoff JB, Howk K, Pikounis B, Mendenhall V, Martin P. Development of a method
for the evaluation of wound tensile strength in cynomolgus macaques. J Pharm Tox
Methods, 57 (2008), 74-79.
21. Mendenhall HV: Book Review: BSAVA Manual of Canine and Feline Anaesthesia and
Analgesia. Journal of Investigative Surgery, 21:47-48, 2008.
22. Mendenhall V, Baran SW, Johnson EJ, Perret-Gentil MI. Aseptic Technique in rodent
surgery: why should I pay attention? Animal Laboratory News. April 2010.
23. Hutchinson RW, Mendenhall V, Abutin RM, Muench T, Hart J. Evaluation of fibrin
sealants for central nervous system sealing in the mongrel dog durotomy model.
Neurosurgery. 2011 October; 69(4): 921-8.
24. Mendenhall V, Baran S, Johnson E, Perret-Gentil M. Aseptic Technique in Rodent
Surgery: Why Should I Pay Attention? ALN World Issue, September/October 2011.
25. Michael A, Buffen E, Rauck R, Anderson W, McGirt M, Mendenhall HV. An in vivo
Canine Study to Assess Granulomatous Responses in the MedStream Programmable
Infusion SystemTM
and the SynchroMed II Infusion System®. Pain Medicine, 13(2): 175-
84, 2012.
26. Buttermann GR, Mendenhall HV. Feasibility of the Runt Cow for in vivo Testing of a
Spinal Interbody Prosthesis with Preliminary Results. J Invest Surg, 25,112-122, 2012.

As of April 6, 2015
27. Schroedter WB, Burke SK, Blair A, Mendenhall HV. Comparison of In Vivo
Arteriovenous Fistula Volume Flow Measurements Using a Transonic Transit-Time
Ultrasound Flow Device and Doppler Ultrasound. J Vasc Ultrasound 38(4) 187-197, 2014.
28. Ding H, Hayashida K, Suto T, Sukhtankar DD, Kimura M, Mendenhall V, Ko MC.
Supraspinal actions of N/OFQ, morphine and substance P in regulating pain and itch in
nonhuman primates. Br J Pharmacol. 2015 Mar 5. doi: 10.1111/bph.13124.
CONFERENCE PROCEEDINGS:
1. Mendenhall HV, Grussing DM, Henderson JD Jr, McPherson GK, Sanford JB, Kennedy
JC, Roth JH. Prosthetic augmentation of autogenous tissue for repair of anterior cruciate
ligament disability, 26th Ann Mtg of the Orthopaedic Res Soc, Atlanta, Georgia, February
5-7, 1980.
2. Mendenhall HV, Grussing DM, Fredell PA, Henderson JD Jr, Case MT, Galbraith W,
Klein GV. A fractionated composite bromelin preparation (R-382) for removal of full
thickness burn eschar in swine, 13th Ann Mtg of the Amer Burn Assoc, Washington, D.C.,
April 2-4, 1981.
3. Mendenhall HV, Grussing DM, Henderson JD Jr, McPherson GK, Sanford JB, Kennedy
JC, Roth JH. 7th Ann Mtg of the Soc for Biomaterials, Troy, New York, May 27-31, 1981.
4. Mendenhall HV. Cruciate ligament surgery, 7th Ann Mtg of the Minn Assoc of Vet Tech,
Minneapolis, Minnesota, January 30-31, 1982.
5. Mendenhall HV. Engineering principles behind polypropylene as a ligament augmentation
device and animal experimentation, Kennedy Lig Augmentation Device Symp, Univ of
Western Ontario, London, Ontario, April 24, 1982.
6. Mendenhall HV. Evaluation of polypropylene as an artificial anterior cruciate ligament in
the dog, Student's Award Papers, 8th Ann Mtg of the Soc for Biomaterials, Orlando,
Florida, April 24-27, 1982.
7. Mendenhall HV, McPherson GK, Plenk HR, Rottmann W, Sanford JB, Grussing DM,
Kennedy JC, Galpin R. Evaluation of the ligament augmentation device after long term
implantation in goats, 8th Ann Mtg of Soc for Biomaterials, Orlando, Florida, April 24-27,
1982.
8. Mendenhall HV, Winter GD, Henderson JD Jr, Fredell PA, Grussing DM, Erickson EH.
Skin grafting in swine following burn eschar debridement with R-832, Int Soc for Burn
Injuries, San Francisco, California, August 29-September 4, 1982.

As of April 6, 2015
9. Fredell P, Solem LD, Ahrenholz DH, Bahmet W, Grussing DM, Mendenhall HV, Erickson
EH, Trancik R. Determination of silver penetration into burn eschar by atomic absorption,
15th Ann Mtg of the Amer Burn Assoc, New Orleans, Louisiana, March 16-19, 1983.
10. Mendenhall HV, McPherson GK, Gibbons DF, Plenk H Jr, Rottmann NW, Sanford JB,
Kennedy JC. Histologic and mechanical evaluation of the ligament augmentation device,
29th Ann Mtg Amer Soc for Artificial Internal Organs, Toronto, Canada, April 28-30, 1983.
11. Mendenhall HV, McPherson GK, Gibbons DF, Plenk H Jr, Rottmann W, Sanford JB,
Grussing DM, Kennedy JC. Evaluation of the ligament augmentation device after two year
implantation in goats, 9th Ann Mtg of Soc for Biomaterials, Birmingham, Alabama, April
27-May 1, 1983.
12. McPherson GK, Mendenhall HV, Sanford JB, Gibbons DF, Kennedy JC. The use of
polypropylene braid as a perioperative facilitator in the repair of chronic anterior cruciate
ligament injuries: the Kennedy LAD, Symp on Artificial Ligaments, New York, New York,
November 30-December 1, 1983.
13. Shapiro JS, Peltier L, Volz R, Mendenhall HV. Power stapling fixation: comparison with
pins, wires and screws, 51st Ann Mtg of the Amer Acad of Orthopaedic Surgeons, Atlanta,
Georgia, February 9-14, 1984.
14. Roth JH, Kennedy JC, McPherson GK, Mendenhall HV, Sanford JB, Gibbons DF. Long
term evaluation of the 'ligament augmentation device' in the reconstruction of the anterior
cruciate ligament in goats, Canadian Orthopaedic Res Soc, Winnipeg, Saskatchewan,
Canada, June 9-11, 1984.
15. Mendenhall HV. Animal studies, Symp on Prosthetic Augmentation of Autogenous Grafts,
St. Paul, Minnesota, November 10, 1984.
16. Mendenhall HV. Development of an animal research protocol, Ann Res Conf, St. Paul-
Ramsey Med Educ and Res Fndtn, St. Paul, Minnesota, November 10, 1984.
17. Mendenhall HV, McPherson GK, Grussing DM, Roth JH. The effect of full thickness
sectioning of the central one third of the patellar tendon and joint immobilization on the
knee joint of goats following reconstruction of the anterior cruciate ligament, 31st Ann Mtg,
Orthopaedic Res Soc, Las Vegas, Nevada, January 20-25, 1985.
18. Roth JH, McPherson GK, Mendenhall H.V. Polypropylene braid augmentation of anterior
cruciate ligament reconstruction - an in-vivo goat study, 52nd Ann Mtg of Amer Acad
Orthopaedic Surgeons, Las Vegas, Nevada, January 25-30, 1985.

As of April 6, 2015
19. Mendenhall HV, McPherson GK, Winter GD, Sanford JB, Kennedy JC, Roth JH.
Evaluation of polypropylene as an artificial anterior cruciate ligament in the dog, Interm
Mtg, Amer Orthopaedic Soc for Sports Med, Las Vegas, Nevada, January 23-24, 1985.
20. Mendenhall HV, Grussing DM, McPherson GK, Lumb WV. A surgical model to study in-
vivo biodegradation of filamentous polymeric biomaterials, 11th Ann Mtg of the Soc for
Biomaterials, San Diego, California, April 25-28, 1985.
21. Mendenhall HV. The domestic white goose as an animal model for intraocular surgery,
2nd Ann Scientific Session, Academy of Surgical Research, Clemson, South Carolina,
October 31-November 1, 1986.
22. Mendenhall HV. The goat as an animal model for anterior cruciate ligament reconstruction,
2nd Ann Scientific Session, Academy of Surgical Research, Clemson, South Carolina,
October 31-November 1, 1986.
23. Holden JP, Grood ES, Butler DL, Noyes FR, Mendenhall HV, VanKampen CL. Fascia lata
autograft reconstruction of the anterior cruciate ligament: Early changes in joint laxity and
graft strength, 33rd Ann Mtg, Orthopaedic Res Soc, San Francisco, California, January 19-
22, 1987.
24. Tountas CP, Bergman RA, Barrows TH, Mendenhall HV, Gibbons DF, Lewis TW, Pyrek
JD, Stone H. Peripheral nerve repair: tubulization vs. suture (a twelve-month primate
study), 42nd Ann Mtg of the Amer Soc for Surg of the Hand, San Antonio, Texas,
September 9-12, 1987.
25. Mendenhall HV. Synthetic augmentation: concept and controversies, 1st European LAD
Study Club, Cannes, France, September 11-12, 1987.
26. Mendenhall HV, Knoll RL, Cameron JD. A histological evaluation of hydrogel intraocular
lens implants in rabbits, 5th Cong of the European Intraocular Implantlens Counc,
Jerusalem, Israel, September 13-18, 1987.
27. Mendenhall HV. Long term evaluation of the ligament augmentation device: wear
characteristics, Int Sports Med Conf, Edmonton, Alberta, September 25-27, 1987.
28. Mendenhall HV. Development of LAD and animal studies, Knee Ligament Reconstruction
with Augmentation, St. Charles Medical Center and Oregon Health Sciences Univ, Sun
River, Oregon, February 20, 1988.
29. Mendenhall HV. Biomechanical and histological review of LAD, Knee Ligament
Reconstruction with Augmentation, St. Charles Med Ctr and Oregon Health Sciences Univ,
Sun River, Oregon, February 20, 1988.

As of April 6, 2015
30. Oestern HJ, Kasperczyk W, Bosch U, Sturm J, Mendenhall HV. Experimental mechanical,
histological and radiographic evaluation of use of the 'Kennedy ligament augmentation
device' (LAD) in posterior cruciate ligament reconstruction in sheep. 3rd Cong of the
European Soc of Knee Surgery and Arthroscopy, Amsterdam, the Netherlands, May 16-
20, 1988.
31. Mendenhall HV, Knoll RL, Cameron JD. A histological evaluation of hydrogel (poly-n-
vinyl-2-pyrrolidone copolymer) intraocular lens implants in rabbits, The 3rd World
Biomaterial Congress, Kyoto, Japan, April 21-25, 1988.
32. Knoll RL, Gibbons DF, Mendenhall HV. Investigation of cell attraction and adherence to
hydrogel (poly-n-vinyl-2-pyrrolidone copolymer) intraocular lens implants, The 3rd World
Biomaterial Cong, Kyoto, Japan, April 21-25, 1988.
33. Mendenhall HV. Investigation of poly-n-vinyl-2-pyrrolidone copolymer IOL explants for
attraction and/or penetration of cells and debris into the hydrogel optic, Biomaterials in
Ophthalmology: Present and Future, Kobe Univ, Kobe, Japan, April 26, 1988.
34. Mendenhall H.V. The concepts of augmentation compared to scaffolding, stents and true
prostheses in ACL reconstruction, Symp: ACL Reconstruction using the Kennedy LAD as
an Augmentation Device, Ortopedkirurgiska klinikens, Danderyd, Sweden, May 9, 1988.
35. Mendenhall HV, Knoll RL, Frederick D.M. Clinical evaluation of intraocular tissue
reactions induced by extracapsular lens extraction and implantation of dehydrated poly-n-
vinyl-2-pyrrolidone posterior chamber intraocular lenses in cynomolgus monkeys, 6th
Cong of the European Intraocular Implantlens Counc, Copenhagen, August 14-18, 1988.
36. Knoll RL, Gibbons DF, Mendenhall HV. Cell attraction and adherence to hydrogel (poly-
n-vinyl-2-pyrrolidone copolymer) intraocular lenses: an experimental study in rabbits, 6th
Cong of the European Intraocular Implantlens Council, Copenhagen, August 18-21, 1988.
37. Mendenhall HV, Knoll RL, Gibbons DF, Snowden FW, Lindstrom RL. Development of
poly-n-vinyl-2-pyrrolidone copolymer hydrogel (P-NVP) as an intraocular lens, Film
Festival, 6th Cong of the European Intraocular Implantlens Council, Copenhagen, August
18-21, 1988.
38. Mendenhall HV. Viscoelastic materials in intraocular surgery, 1st Int Symp on Quality of
Cataract Surgery, Stockholm, Sweden, August 19-20, 1988.
39. Mendenhall HV. Bone-patellar tendon-bone anterior cruciate ligament substitution in
goats, 4th Ann Scientific Session of the Academy of Surgical Research, Boston,
Massachusetts, September 15-17, 1988.

As of April 6, 2015
40. Mendenhall HV, Frederick DM, Knoll RL. Extra-capsular lens extraction and implantation
of posterior chamber intraocular lenses in cynomolgus monkeys: Preoperative preparation,
operative technique and postoperative care, 4th Ann Scientific Session of the Academy of
Surgical Research, Boston, Massachusetts, September 15-17, 1988.
41. Knoll RL, Mendenhall HV, Gibbons DF, Cameron JD. A histological evaluation of
hydrogel (poly-n-vinyl-2-pyrrolidone copolymer) intraocular lens implants in cynomolgus
monkeys, The 15th Ann Mtg of the Soc for Biomaterials, Lake Buena Vista, Florida, April
28-May 2, 1989.
42. Mendenhall HV. Biology of ligament augmentation - a 10 year overview, A Day in Sports
Med, Toronto, Canada, April 29, 1989.
43. Knoll RL, Mendenhall HV, Gibbons DF, Cameron JD. Evaluation of hydrogel (poly-n-
vinyl-2-pyrrolidone (P-NVP)) as an IOL in cynomolgus monkeys, Biomaterials in
Ophthalmology, 1st Interdisciplinary Symp, Bologna, Italy, September 1-4, 1989.
44. Mendenhall H.V. Development of poly-n-vinyl pyrrolidone (P-NVP)) as a small incision
IOL, 1st World Cong on Phacoemulsification and Small Incision IOL, Monte Carlo,
45. Mendenhall HV. The concept of synthetic augmentation of biologic tissue: 15 years of
basic research, PWV Arthroscopy Soc Mtg, Johannesburg, South Africa, October 12, 1989.
46. Mendenhall HV. Evaluation of a microvascular anastomotic device in the dog, British
Microsurgical Soc Mtg, Glasgow, January 25-26, 1990.
47. Mendenhall HV. Biology of ligament augmentation, 10th Ann Whistler Sports Med Conf,
Whistler, British Columbia, Canada, February 2-4, 1990.
48. Goertzen MJ, Mendenhall HV, Schultz KPL, Arnoczky, S.P. ACL reconstruction using
anterior cruciate ligament allografts in dogs. Results with and without ligament
augmentation device (LAD), 38th Ann Mtg of the Orthopaedic Res Soc, New Orleans,
Louisiana, February 5-8, 1990.
49. Mendenhall HV. The biology of synthetic augmentation of anterior cruciate ligament
(ACL) substitutions, 1st Workshop of the European Orthopaedic Res Soc, Aarhus,
Denmark, July 7, 1990.
50. Mendenhall HV. Animal studies with the ligament augmentation device, 4th LAD Study
Club, Edinburgh, October, 1991.

As of April 6, 2015
substitutions, Invited Lecture: 2nd Cong of Knee and Orthopaedic Sports Med Sect of the
West Pac Orthopaedic Assoc, Seoul, Korea, July 3-6, 1991.
52. Mendenhall HV. Animal studies related to surgical technique and rehabilitation in
synthetic augmentation of autogenous tissue for anterior cruciate ligament substitution,
Invited Lecture: 2nd Cong of Knee and Orthopaedic Sports Med Sect of the West Pac
Orthopaedic Assoc, Seoul, Korea, July 3-6, 1991.
53. Mendenhall HV. La biomecanique pour une augmentation synthetique reussie du croise
anterieur, Assoc D-Orthopedie du Quebec. Reunion Scientifique, Beaupre, Mont Sainte-
Anne, Quebec, Canada, February 22-23, 1992.
substitutes - animal studies and clinical considerations, Invited Lecture: Symp:
Bandchirurgie des Kniegelenkes und Bandaugmentation. Eine aktuelle
Standortbestimmung, Marburg, Germany, March 20, 1992.
55. Mendenhall HV. Biomechanics of knee ligament reconstruction, A Day in Sports Med,
Toronto, Canada, April 11, 1992.
56. Mendenhall HV. Basic research on the biology of synthetic augmentation, Symp on the
Cruciate Deficient Knee-Knee Ligament Reconstruction, Winnipeg, Canada, May 1, 1992.
57. Mendenhall HV. Biomechanics of knee ligament reconstruction, Update on Knee Ligament
Reconstruction, London, Ontario, Canada, June 13, 1992.
58. Mendenhall HV. Biomechanics of knee ligament reconstruction, A Day In Sports Medicine
- Toward Year 2000, Ottawa, Ontario, Canada, October 3, 1992.
59. Mendenhall HV. Biomechanics of knee ligament reconstruction, Current Concepts in Knee
Ligament Surgery, Vancouver, Canada, October 17, 1992.
60. Mendenhall HV. An External Thoracic Duct-Venous Shunt to Allow for Long Term
Collection of Lymph and Blood in the Conscious Pig, Society of Toxicology, Baltimore,
Maryland, March 8, 1995.
61. Cornell S, Mendenhall HV. 44 Days of Continuous Infusion into the Intrathecal Space of
Beagle Dogs using an Indwelling Catheter, Society of Toxicology, Baltimore, Maryland,
March 8, 1995.
62. Mendenhall HV. Surgical Techniques in Device Testing, 1995 Technical Workshop,
Society for Biomaterials, San Francisco, California, March 18, 1995.

As of April 6, 2015
63. Horvath CJ, Garlick D, Darrigrand A, Mendenhall HV, An Improved Anesthesia
Technique in Rabbits, Laboratory Animal Medicine Section of the American Veterinary
Medical Association, Pittsburgh, Pennsylvania, July 12, 1995.
64. Kobayashi H, Kawamoto Y, Hara S, Tomizawa N, Gibbons DF, VanKampen CL,
Mendenhall HV. Study on Bioresorbable Poly-L-Lactide (PLLA) Ligament Augmentation
Device (LAD). Proc. 4th Japan International Society for the Advancement of Material and
Process Engineering Symposium, Tokyo, Japan, September 25-28, 1995
65. Mendenhall HV, Cornell S. 44 Days of Continuous Infusion into the Intrathecal Space of
Beagle Dogs Using an Indwelling Catheter, 11th
Annual Scientific Session of the Academy
of Surgical Research, Albuquerque, New Mexico, October 5-7, 1995. Published in the
Journal of Investigative Surgery, 1995, 8(4): p 317.
66. Mendenhall HV, Piechowiak M, Bayer KB. An External Thoracic Duct-Venous Shunt to
allow for Long Term Collection of Lymph and Blood in the Conscious Pig, 11th Annual
Scientific Session of the Academy of Surgical Research, Albuquerque, New Mexico,
October 5-7, 1995.
67. Mendenhall HV. A Clinically Applicable Animal model for Evaluation of Bone Graft
Substitutes and Implantable Delivery Systems for Bone Repair, 11th
Annual Scientific
Session of the Academy of Surgical Research, Albuquerque, New Mexico, October 5-7,
1995. Published in the Journal of Investigative Surgery, 1995, 8(4): p 318.
68. Mendenhall HV, Horvath C, Piechowiak M, Johnson L, Bayer K. An External Thoracic
Duct-Venous Shunt to allow for long term collection of lymph and blood in the
conscious pig, Swine in Biomedical Research, International Symposium, College Park,
Maryland, October 22-25, 1995.
69. Mendenhall HV, Chronic Catheterization of the Lateral Ventricle in Cynomolgus
Monkeys, 3rd US-Japan Symposium on Drug Delivery Systems, Maui, Hawaii, December
17-22, 1995
70. Piechowiak M, Mendenhall HV, Chronic Percutaneous Catheterization of the Jugular Vein
in Mice, 3rd US-Japan Symposium on Drug Delivery Systems, Maui, Hawaii, December
17-22, 1995.
71. Piechowiak M, Mendenhall HV, Chronic Percutaneous Catheterization of the Jugular Vein
in Mice, 35th Annual Meeting of the Society of Toxicology, Anaheim, California, March
10-14, 1996.
72. Mendenhall HV, Chronic Catheterization of the Lateral Ventricle in Cynomolgus
Monkeys, 35th Annual Meeting of the Society of Toxicology, Anaheim, California, March
10-14, 1996.

As of April 6, 2015
73. Mendenhall HV, Surgical Technique to allow for Chronic Catheterization of the Lateral
Ventricle in Cynomolgus Monkeys, Exhibit Hall Demonstration, 35th Annual Meeting of
the Society of Toxicology, Anaheim, California, March 10-14, 1996.
74. Mendenhall HV, Moderator: Laboratory Animal Long-Term Access Roundtable,
Philadelphia, Pennsylvania, May 10, 1996.
75. Mendenhall HV, Piechowiak M. Chronic Catheterization of the Lateral Ventricle in
Cynomolgus Monkeys, 12th Annual and 1st International Scientific Session of the
Academy of Surgical Research, Muenster, Germany, October 3-5, 1996. Published in the
Journal of Investigative Surgery, 1996, 9(3): p 260.
76. Piechowiak M, Wadanoli M, Mendenhall HV. Technique for Implantation of a Catheter
to Allow for Infusion of Test Articles into the Intrathecal Space of the Rat. 12th Annual
and 1st International Scientific Session of the Academy of Surgical Research, Muenster,
Germany, October 3-5, 1996. Published in the Journal of Investigative Surgery, 1996, 9(3):
p 208.
77. Chen SA, Sawchuck RJ, Brundate RC, Horvath C, Mendenhall HV, Braeckman RA.
Plasma and Lymph Pharmacokinetics of Recombinant Interleukin-2 (IL-2) and
Polyethylene Glycol Modified IL-2 (PEG IL-2) in Female Pigs. National Meeting of the
American Association of Pharmaceutical Research, Seattle, Washington, October 12,
1996.
78. Mendenhall HV. Modern Methods of Anterior Cruciate Ligament (ACL) Repair. 53rd
Annual Conference of the Japanese Society of Veterinary Anesthesia & Surgery. Invited
Lecture. Morioka, Japan, November 2-3, 1996. Published in the Japanese Journal of
Veterinary Anesthesia & Surgery, 1996, 27 (Suppl 2): 2-10.
79. Mendenhall HV. A Clinically Applicable Animal Model for Evaluation of Bone Graft
Substitutes and Implantable Delivery Systems for Bone Repair. 53rd Annual Conference
of the Japanese Society of Veterinary Anesthesia & Surgery. Invited Lecture. Morioka,
Japan, November 2-3, 1996. Published in the Japanese Journal of Veterinary Anesthesia
& Surgery, 1996, 27 (Suppl 2): 11-18.
80. Mendenhall HV. Experimental Extracapsular Cataract (Lens) Removal and Posterior
Intraocular Artificial Lens (IOL) Implantation in Cynomolgus Monkeys with Reference to
Clinical IOL Implantation in Dogs. 53rd Annual Conference of the Japanese Society of
Veterinary Anesthesia & Surgery. Invited Lecture. Morioka, Japan, November 2-3, 1996.
Published in the Japanese Journal of Veterinary Anesthesia & Surgery, 1996, 27 (Suppl
2): 19-28.

As of April 6, 2015
81. Horvath C, Mendenhall HV, Piechowiak M, Wadanoli M. A Method to Allow for Direct
Administration of Test Articles to the Liver of Domestic Swine. 36th Annual Meeting,
Society of Toxicology. Cincinnati, Ohio, March 9-13, 1997.
82. Mendenhall HV, Piechowiak M, Wadanoli M, Horvath C. Surgical Catheterization of the
Urinary Bladder to Allow for Multiple Direct Infusions of Test Articles or Urine Collection
Over an Extended Period in Conscious Swine. 36th Annual Meeting, Society of Toxicology.
Cincinnati, Ohio, March 9-13, 1997.
83. Piechowiak M, Wadanoli M, Mendenhall HV, Horvath C: Surgical Catheterization of the
Urinary Bladder to Allow for Multiple Direct Infusions of Test Articles or Urine Collection
over an Extended Period in Conscious Rats. 36th Annual Meeting, Society of Toxicology.
Cincinnati, Ohio, March 9-13, 1997.
84. Wadanoli M, Piechowiak M, Mendenhall HV: Surgical Technique for Implantation of a
Urinary Catheter for Intracystic Delivery of Test Article and Sample Collection in the
Beagle. 36th Annual Meeting, Society of Toxicology. Cincinnati, Ohio, March 9-13, 1997.
85. Mendenhall HV Surgical Techniques in Device Testing, 1997 Technical Workshop,
Society for Biomaterials, New Orleans, Louisiana, April 30, 1997.
86 Mendenhall HV, Piechowiak M, Gamba-Vitalo C, Lilja H. Chronic Catheterization of the
Lateral Ventricle in Cynomolgus Monkeys. 1st International Conference of Asian Society
of Toxicology, Yokohama, Japan, June 29-July 2, 1997. Published in the Journal of
Toxicological Sciences, Vol 23, Supplement II, 1998, p 353.
87. Wadanoli M, Piechowiak M, Mendenhall HV, Lilja H. Instrumentation to Allow for
Long Term Intracystic Delivery of Test Articles and Urine Collection in the Conscious
Beagle Dog. 1st International Conference of Asian Society of Toxicology, Yokohama,
Japan, June 29-July 2, 1997.
88. Wadanoli M, Piechowiak M, Mendenhall HV, Lilja H. Instrumentation to Allow for
Long Term Intracystic Delivery of Test Articles and Urine Collection in the Conscious
Beagle Dog. Thirteenth Annual Scientific Session of the Academy of Surgical Research,
San Antonio, Texas, September 4-6, 1997.
89. Mendenhall HV, Piechowiak M, Wadanoli M, Horvath C: A Dual Implantable Urinary
Catheter System for Chronic Infusion and Urine Collection in Conscious Swine. Thirteenth
Annual Scientific Session of the Academy of Surgical Research, San Antonio, September
4-6, 1997.

As of April 6, 2015
90. Piechowiak M, Wadanoli M, Mendenhall HV, Horvath C: Surgical Instrumentation of Rats
to Allow for Chronic Direct Infusion into the Urinary Bladder over an Extended Period in
the Conscious Animal. Thirteenth Annual Scientific Session of the Academy of Surgical
Research, San Antonio, Texas, September 4-6, 1997.
91. Horvath C, Mendenhall HV, Piechowiak M, Wadanoli M. Long-Term Catheterization of
the Gastroduodenal Artery to Allow for Direct Administration of Test Articles to the Liver
in Conscious Yorkshire Swine. Thirteenth Annual Scientific Session of the Academy of
Surgical Research, San Antonio, Texas, September 4-6, 1997.
92. Mendenhall HV, Piechowiak M, Wadanoli M. Evaluation of BICCS® Bile Access System
in Beagle Dogs and Cynomolgus Monkeys. Access Technologies 1997 Laboratory Animal
Long-Term Access Roundtable, San Antonio, September 4, 1997.
93. Mendenhall HV, Piechowiak M, Wadanoli M, Raikowski D. A Long Term Study on the
Use of Vascular Access Ports in Multiple Species. Access Technologies 1997 Laboratory
Animal Long-Term Access Roundtable, San Antonio, September 4, 1997.
94. Mendenhall HV, Markham P. Bile Access System for Pharmacokinetics and Disposition
Studies in Nonhuman Primates and Dogs. Eighth North American International Society for
the Study of Xenobiotics, Hilton Head, South Carolina, October 26-30, 1997.
95. Sites JP, York TA, Hermann RP, Mendenhall HV. Systemic Perfusion Hyperthermia
techniques: control studies in canines. Veterinary Cancer Society/Society for Radiologic
Medicine, Chicago, IL, December, 1997.
96. Mendenhall HV. Selective Catheterization of the Internal Carotid Artery in Pigs.
Interventional Radiology Roundtable, in conjunction with the 14th Annual Meeting of the
Academy of Surgical Research, Nashville, Tennessee, October 1-3, 1998.
97. Mendenhall HV. Moderator, 3rd Annual Long-Term Access Roundtable in conjunction
with the 14th Annual Meeting of the Academy of Surgical Research, Nashville, Tennessee,
October 1-3, 1998.
98. Mendenhall HV. Bile Access in Monkeys. 3rd Annual Long-Term Access Roundtable in
conjunction with the 14th Annual Meeting of the Academy of Surgical Research.
Nashville, Tennessee, October 1-3, 1998.
99. Mendenhall, HV. Vascular Access Ports in General. 3rd Annual Long-Term Access
Roundtable in conjunction with the 14th Annual Meeting of the Academy of Surgical
Research, Nashville, Tennessee, October 1-3, 1998.

As of April 6, 2015
100. Mendenhall, HV, Markham P, Piechowiak M. Multiple Catheterization of the Internal Iliac
Vein and the Urinary Bladder to Allow for Assessment of Renal Function over Extended
Periods of Time in Conscious Cynomolgus Monkeys. 14th Annual Meeting of the Academy
of Surgical Research, Nashville, Tennessee, October 1-3, 1998.
101. Mendenhall HV. Surgical Techniques in Cardiovascular Device Testing. 7th International
Symposium, Cardiac Surgery in the 1990's. St. Thomas, USVI, November 4-8, 1998.
102. Mendenhall HV. Moderator, First European Laboratory Animal Long-Term Access
Roundtable, Amsterdam, the Netherlands, June 7, 1999.
103. Mendenhall HV. Update on the Use of Chronic Vascular Access Ports (VAPs) in
Laboratory Animal Species. First European Laboratory Animal Long-Term Access
Roundtable, Amsterdam, The Netherlands, June 7, 1999.
104. Mendenhall HV, Lane J, Sites JP. Techniques to Maximize Survival of Calves Undergoing
Cardiopulmonary Bypass. XII World Congress of International Society for Artificial
Organs and XXVI Congress of European Society for Artificial Organs. Edinburgh, UK,
August 3-6, 1999.
105. Mendenhall HV, Lane J, Sites JP. Techniques to Maximize Survival of Calves Undergoing
Cardiopulmonary Bypass. 15th
Annual Meeting, Academy of Surgical Research, Scottsdale,
Arizona, September 2-4, 1999.
106. Mendenhall HV. Use of a Jejunal Intussuscepted “Nipple Valve” for Long-Term Intestinal
Access in the Yucatan Micro-Pig. 15th
Annual Meeting, Academy of Surgical Research,
Scottsdale, Arizona, September 2-4, 1999.
107. Mendenhall HV. Radiographic Evaluation of Controlled Release Coatings Delivered
Directly to the Jejunum of Yucatan Micro-Pigs via a Jejunal Intussuscepted “Nipple
Valve”. 15th
Annual Meeting, Academy of Surgical Research, Scottsdale, Arizona,
108. Duncan P.E., Mendenhall H.V., Hazard Analysis & Risk Assessment as a Tool for
PreClinical Study Planning. Medical Valley Workshop, Minneapolis, MN, February 9,
2000.
109. Mendenhall H.V., Techniques to Maximize Survival of Calves Undergoing
Cardiopulmonary Bypass. Seminar in Advances in Cardiovascular Testing, Society of
Toxicology, Philadelphia, Pennsylvania, March 19, 2000.

As of April 6, 2015
110. Duncan P.E., Mendenhall H.V., Hazard Analysis & Risk Assessment as a Tool for
PreClinical Study Planning. Corporate Forum, Sixth World Biomaterial Congress,
Kamuela, Hawaii, May 16, 2000.
111. Duncan P.E., Mendenhall H.V., Optimizing Study Design Through Risk Control: Animal
Study Planning for Clinical Trial Success. Corporate Forum, Sixth World Biomaterials
Congress, Kamuela, Hawaii, May 16, 2000.
112. Mendenhall, HV. Vascular Access Ports Overview: 1995-2000. Fifth Annual Laboratory
Animal Long-Term Access Roundtable, Cincinnati, Ohio, October 19, 2000.
113. Mendenhall HV. Hazard Analysis & Risk Assessment as a Tool for Pre-Clinical Study
Planning. Corporate Forum, 16th
Annual Meeting, Academy of Surgical Research,
Cincinnati, Ohio, October 20, 2000.
114. Mendenhall HV. Hazard Analysis & Risk Assessment In Pre-Clinical Studies: The
Importance Of Asepsis, Surgical Technique And Choosing The Appropriate Animal
Model. 2001 Laboratory Animal Welfare Training Exchange (L.A.W.T.E.) Conference. St.
Louis, Missouri, August 2, 2001.
115. Mendenhall HV. The Biomechanics, Biochemistry and Pathophysiology of Synthetic
Augmentation of Soft Tissue, 17th
Annual Meeting, Academy of Surgical Research, San
Diego, California, October 4, 2001.
116. Howk K, Mendenhall HV. A Model for Lateral Ventricular Drug Administration and
Cerebrospinal Fluid Collection Via Cranial Ports in Conscious Beagle Dogs. 17th
Annual
Meeting, Academy of Surgical Research, San Diego, California, October 5, 2001.
117. Mendenhall, HV. Panel Member: “Bringing a Biomaterial-Based Product from the Bench
to the Clinic: Controversial Issues Along the Pipeline. Evaluation of Material Performance
(Animal Models)”. 28th
Annual Meeting Society for Biomaterials, Tampa, Florida, April
26, 2002.
118. Mendenhall, HV. The Anesthesia, Pharmacological, and Adjunctive Surgical Management
of Thoracoabdominal Bypass Grafting in Pigs. 18th
Annual Academy of Surgical Research,
Greenville, South Carolina, October 4th
, 2002.
119. Bayer, K, Mendenhall, HV, Howk, K, LaRochelle, A. Continuous Infusion to the Lateral
Ventricle of the Beagle Dog. 18th
Annual Academy of Surgical Research, Greenville, South
Carolina, October 4th
, 2002.
120. Bayer, K, Pepin, M, Mendenhall, HV, LaRochelle, A. Catheterization of the Cerebral
Subarachnoid Space for Continuous Intrathecal Infusion in Sprague-Dawley Rats. 18th
Annual Academy of Surgical Research, Greenville, South Carolina, October 4th
, 2002.

As of April 6, 2015
121. Mendenhall, HV, DesPlaines, D., Bayer, K., LaRochelle, A. Jugular and Femoral Vein
Vascular Access Ports (VAPs) in Pigs. 18th
Greenville, South Carolina, October 4th
, 2002.
122. Mendenhall, HV, LaRochelle, A. The Use Of Implantable Pumps To Conduct Toxicity
Studies Involving Continuous Intracranial Infusion To Beagle Dogs. 19th
Annual Academy
of Surgical Research, St. Louis, Missouri, October 3rd
, 2003.
123. Mendenhall, HV, Cunningham, MR, Kellar, RS. Sternotomy as a Surgical Approach for
Studies Requiring a Second Thoracotomy in Dogs. 19th
Annual Academy of Surgical
Research, St. Louis, Missouri, October 3rd
, 2003.
124. Wright, TL, Smits, G, Mendenhall, HV. Effects of Medetomidine/Ketamine and
Thiobutabarbital on Selected Blood Gas Parameters in Anesthetized Rats. 19th
Annual
Academy of Surgical Research, St. Louis, Missouri, October 3rd
, 2003.
125. DesPlaines, D, Mendenhall, HV, Wilson, S, Cunningham MR. Implantation of the
Respiratory Telemetry Device in Beagle Dogs. 19th
St. Louis, Missouri, October 3rd
, 2003.
126. Suganuma, A, Mendenhall, HV, Sites, JP, Kaneko, K, Nedelman, M, Kerns, WD. Safety
Evaluation of E5564, a Toll-like Receptor 4 (TLR4) Antagonist, on Cardiopulmonary
Bypass (CPB) Surgery in Dogs by Intravenous Infusion. 43rd
Annual Meeting of the Society
of Toxicology, Baltimore, Maryland, March 23, 2004.
127. Bugelski, PJ, Martin, EC, Mendenhall, HV, Soderman. AR, Tam, SH, Picha, KM,
Khandekar, VS, Treacy, G. A humanized anti-tissue factor monoclonal antibody (CNTA
859) does not increase the risk of surgical bleeding in a cynomolgus monkey model. 43rd
Annual Meeting of the Society of Toxicology, Baltimore, Maryland, March 23, 2004.
128. Mendenhall, HV. Acid-Base Balance and Anesthetic Management in Cardiovascular
Surgery. Douglas M. Cromeens Memorial Keynote Address. 20th
Annual Academy of
Surgical Research Meeting, Minneapolis, Minnesota, October 7-9, 2004.
129. Mendenhall, HV, Wilson, S, Coatney, B, Flegal, M. Implantation of the DSI Left
Ventricular and Direct Arterial Pressure Telemetry Transmitter. 20th
Annual Academy of
Surgical Research Meeting, Minneapolis, Minnesota, October 7-9, 2004.
130. Mendenhall, HV. The Small Cow as an Animal Model for Lumbar Intervertebral Disc
Replacement. Podium Presentation. International Meeting on Advanced Spine Techniques,
Banff, Alberta, Canada, July 7-9, 2005.

As of April 6, 2015
131. Mendenhall, HV. Bilateral versus Unilateral Aorto-Iliac Vein Vascular Grafting in Swine.
21st
Annual Academy of Surgical Research Meeting, Philadelphia, Pennsylvania,
132. Mendenhall, HV. The Small Cow as an Animal Model for Lumbar Intervertebral Disc
Replacement. Poster Presentation. 20th
Annual Meeting, North American Spine Society,
Philadelphia, Pennsylvania, September 27-October 1, 2005.
133. Mendenhall, HV. A Combination of Intestinal Cannulation with a Jejunal Conduit for Long
Term Intestinal Cannulation in Mini-Swine. Johnson and Johnson Symposium on
Correlating Preclinical Models to Clinical Outcomes, Somerville, New Jersey, December
6-7, 2005.
134. Mendenhall, HV. Animal Models for Device Development for use in the Gastro-Intestinal
Tract. Johnson and Johnson Symposium on Correlating Preclinical Models to Clinical
Outcomes, Somerville, New Jersey, December 6-7, 2005.
135. Warnock, DF, Huibregtse, BA, Mendenhall, HV, Murphy, MP, Poff, BC. Model
Development for Evaluation of a Dialysis Access Graft. 22nd
Research Meeting, Scottsdale, Arizona, September 21-23, 2006.
136. Mendenhall, HV. Cardiovascular Anesthesia Management—Keeping the animal
homeostatic for long and difficult procedures. SNEAALAS 2006 Year End Meeting.
Foxwoods Casino, Ledyard, CT, October 27, 2006.
137. Qiu, QQ, Mendenhall, HV, Garlick, D., Connor, J. DBM/AM Composite for Bone Repair.
53rd
Annual Meeting of the Orthopedic Research Society, San Diego, California, February
11-14, 2007.
138. Mendenhall, HV. Preliminary Animal Testing for a Test Article’s Potential Efficacy in
Treating Adult Macular Degeneration. IBC’s 4th
International Conference on Ocular Anti-
angiogenesis. Cambridge, Massachusetts, April 16-17, 2007.
139. Qiu, QQ, Mendenhall, HV, Garlick, DS, Connor, J. Evaluation of Bone Regeneration
within a Critical-Sized Defect in Athymic Rats Utilizing a DBM/AM Composite. Society
for Biomaterials 2007 Annual Meeting, Chicago, Illinois, April 18-21, 2007.
140. Mendenhall, HV. Surgical animal models of cardiovascular disease. AACC Animal
Division Spring Meeting on Animal Models of Human Disease, Bridgewater, New Jersey,
April 20, 2007.
141. Mendenhall, HV. Anesthetic Management in Cardiovascular Surgery. 2007 AALAS
Tribranch Symposium, Atlantic City, New Jersey, June 10-12, 2007.

As of April 6, 2015
142. Mendenhall, HV. Basic Surgical Knowledge: Principles & Practices. 21st
Annual Charles
River Short Course on Laboratory Animal Science, Newton, Massachusetts, June 18-21,
2007.
143. Mendenhall, HV. The Rabbit as an Animal Model to Allow for Preliminary Testing for
Possible Treatments of Adult Macular Degeneration. 23rd
Research Meeting, Clearwater Beach, Florida, September 27-29, 2007
144. Mendenhall, HV. The Principles and Practices of Experimental Surgery. 23rd
Annual
Academy of Surgical Research Meeting, Clearwater Beach, Florida, September 27-29,
2007
145. Qiu, QQ, Mendenhall, HV, Garlick, DS, Connor, J. Bone Regeneration Induced by a
DBM/AM Composite within Critical-Size Calvarial Defects in Athymic Rats. 23rd
Annual
Academy of Surgical Research Meeting, Clearwater Beach, Florida, September 27-29,
2007
146. Mendenhall, HV. Surgical Technique for Infusion of Potential Chemotherapeutic Agents
to the Liver via the Hepatic Artery. 58th
AALAS National Meeting, Charlotte, North
Carolina, October 13-18, 2007.
147. Mendenhall, HV. Basic Surgical Knowledge: Principles & Practices. 22ndt
Annual Charles
River Short Course on Laboratory Animal Science, Newton, Massachusetts, June 16-19,
2008.
148. Mendenhall, HV. Animal Models for Duraplasty Studies: Dog versus Swine. 2008 Annual
Meeting of the Congress of Neurological Surgeons, Orlando, Florida, September 20-25,
2008.
149. Mendenhall, HV, Abutin, R, Stricker-Krongrad, A. An Improved and Reliable Technique
for Determining the Efficacy of Dural Sealants. 2008 Annual Meeting of the Congress of
Neurological Surgeons, Orlando, Florida, September 20-25, 2008.
150. Mendenhall, HV. The Principles of Surgical Research. Plenary Lecture: 24th
Annual
Meeting of the Academy of Surgical Research, Indianapolis, Indiana, November 6-8, 2008.
151. Mendenhall, HV. Aseptic Surgical Technique. 24th
Annual Meeting of the Academy of
Surgical Research, Indianapolis, Indiana, November 6-8, 2008.
152. Mendenhall, HV, Abutin, R, Stricker-Krongrad, A. An Improved and Reliable Technique
for Determining the Efficacy of Dural Sealants. 24th
Annual Meeting of the Academy of
Surgical Research, Indianapolis, Indiana, November 6-8, 2008.

As of April 6, 2015
153. Mendenhall, HV. Animal Models for Duraplasty Studies: Dog versus Swine. 24th
Annual
Meeting of the Academy of Surgical Research, Indianapolis, Indiana, November 6-8, 2008.
154. Burke, SK, Franano, FN, LaRochelle, A, Mendenhall, HV. Local Application of
Recombinant Human Type I Pancreatic Elastase (PRT-201) to an Arteriovenous Fistula
(AVF) Increases AVF Blood Flow in a Rabbit Model. American Society of Nephrology,
41st Annual Meeting & Scientific Exposition, Philadelphia, Pennsylvania, November 4-9,
2008.
155. Burke, SK, Mendenhall, HV, LaRochelle, AW, Franano, FN. Recombinant Human
Pancreatic Elastase (PRT-201) Dilates the Arteriovenous Graft (AVG) Outflow Vein and
Increases Graft Blood Flow in a Porcine Femoral AVG Model. 6th International Congress
on Vascular Access, Rome, Italy, April 20-22, 2009.
156. Mendenhall, HV. An Overview of Critical Size Bone Defect Animal Models. 25th
Annual
Meeting of the Academy of Surgical Research, New Orleans, Louisiana, September 24-26,
2009.
157. Baran, SW, Hallman TM, Kehler J, Mendenhall V, Perret-Gentil MI, Schantz JD, Johnson EJ.
Basic Principles of Rodent Surgery. Veterinary Bioscience Institute. January 2009.
http://vetbiotech.com/course.php?courseID=44
158. Burke SK, Blair A, Mendenhall HV, Stanley J, Groothuis A. Topical Elastase Increases
AVG Outflow Vein Diameter and Lumen Area in a Swine Model. Angioaccess for
Hemodialysis, Vascular Access Society, Tours, France, June 14-16, 2010.
159. Mendenhall HV. “Working” versus “Non-working” Heterotopic Heart Transplantation.
26th
Annual Meeting of the Academy of Surgical Research, Clearwater Beach, Florida,
September 30-October 2, 2010.
160. Mendenhall HV, Bernal J, Moddrelle D. Cardiovascular Surgery in the non-human
primate. Techniques and Challenges. 61st
AALAS National Meeting, Atlanta, Georgia,
October 10-14, 2010.
161. Mendenhall HV. Hazard and Risk Analysis: Pre-Clinical Study Planning (Animal Studies).
27th
Annual Meeting of the Academy of Surgical Research, Austin, Texas, October 27-29,
2011.
162. Mendenhall HV. Anesthetic Management in Cardiovascular Surgery. 2012 Virtual
Laboratory Animal Science BioConference, February 15-16, 2012.
163. Mendenhall, HV. Practicing the Art of Surgical Research in the Development of New
Medical Devices and Pharmaceuticals. The Surgical Knowledge Exchange Seminar,
Collegeville, Pennsylvania, March 15, 2012.

As of April 6, 2015
164. Mendenhall HV. Lateral Ventricular Ports for Drug Administration or Cerebrospinal Fluid
(CSF) Collection in Canines and Non-Human Primates. The 2012 Turnkey Conference,
10th
Annual Conference, Baltimore, Maryland, April 12-13, 2012.
165. Schroedter WB, Burke SK, Mendenhall VM, Blair A. Comparison of in-vivo arteriovenous
fistula volume flow measurements using a Transonic transit time ultrasound flow device
and Doppler ultrasound. Society for Vascular Ultrasound, 2012 SVU Annual Conference,
National Harbor, Maryland, June 7-9, 2012. D.E. Strandness, MD, Scientific Award for
Excellence in Research.
166. Pielemeier RT, Sweet J, Mendenhall HV, Geddings B, Adrian S, Almazan C, Ramsey H.
Critical Size Tibial Defect in Sheep: Notes on Improving Plating Techniques and Post-
Operative Management. 28th Annual Meeting of the Academy of Surgical Research,
Charlotte, North Carolina, October 3-6, 2012.
167. Mendenhall HV. Keynote Speaker: Practicing the Art of Surgical Research in the
Development of New Medical Devices and Pharmaceuticals. 28th Annual Meeting of the
Academy of Surgical Research, Charlotte, North Carolina, October 3-6, 2012.
168. Tawoda L, Pielemeier R, Mendenhall HV, Adrian S, LaBar M, Newell I, Rindfield T,
Wilson S, Johnson M. Achilles Tendon Repair: Development of a Surgical Technique for
Application of Biomaterials in a Rabbit Model. Society for Biomaterials, Fall Symposium,
New Orleans, LA, October 4-6, 2012.
169. Mendenhall HV. An Overview of Critical Size Bone Defect Animal Models. 2013 Virtual
Laboratory Animal Science BioConference, February 13-14, 2013.
170. Mendenhall HV. Utilization of the Swine Model within Translational Medicine for the
Development of New Cardiovascular and Wound Healing Therapies. The 2013 Turnkey
Conference, 11th Annual Conference, Baltimore, Maryland, April 16-17, 2013.
171. Mendenhall HV. Neurosurgical Animal Models. The 2013 Turnkey Conference, 11th
Annual Conference, Baltimore, Maryland, April 16-17, 2013.
172. Cunningham C, Baran SW, Douglas AT, Flynn DM, McCloud JE, Mendenhall HV.
Chostochondral Thoracotomy as a Means to Access the Left Ventricular Apex for
Intracardiac Injection in the Rat. 29th Annual Meeting of the Academy of Surgical
Research, Clearwater Beach, Florida, September 25-28, 2013.

As of April 6, 2015
173. Mendenhall HV, Giegengack M, Wagner BJ, McCloud JE, Flynn DM, Cunningham C,
Douglas AT. Technical Procedures Necessary to Achieve Successful Endothelial
Keratoplasty in the Cat. 29th Annual Meeting of the Academy of Surgical Research,
Clearwater Beach, Florida, September 25-28, 2013.
174. Goody R, Whittaker S, Henry S, Brookes R, Struharik M, Nisbett E, Morton X, Wilson C,
Mendenhall V, Lawrence M. Development of a chronic hypertension-induced model of
left ventricular hypertrophy and diastolic dysfunction in the St. Kitts green monkey.
NIH/NHLBI Symposium on Cardiovascular Regenerative Medicine, Natcher Conference
Center, Bethesda, MD, September 25-26, 2013.
175. Mendenhall HV. Surgical Animal Models of Cardiovascular Disease. Ask the Experts –
Achieving Successful Preclinical Cardiovascular Studies. Wake Forest Innovations
Seminar, October 29, 2013.
176. Mendenhall HV. Trials and Tribulations of the Refinement of Femoral Critical Sized
Defects in the Rat. 30th
Annual Meeting of the Academy of Surgical Research, Minneapolis,
MN, September 18-20, 2014.
177. Mendenhall HV. Chronic Lymph Collection in the Canine. 30th Annual Meeting of the
Academy of Surgical Research, Minneapolis, MN, September 18-20, 2014.
178. Mendenhall HV. Surgical Technique to Allow for Single, Intermittent or Continuous
Infusion of Potential Chemotherapeutic Agents Directly to the Liver of Selected
Laboratory Animals via the Proper Hepatic Artery. 30th Annual Meeting of the Academy
of Surgical Research, Minneapolis, MN, September 18-20, 2014.
179. Mendenhall HV. Surgical Animal Models of Cardiovascular Disease. 30th Annual Meeting
of the Academy of Surgical Research, Minneapolis, MN, September 18-20, 2014.RCINE
FEMORAL A VG MODEL

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