ANIMALS USED IN EXPERIMENTAL PHARMACOLOGY CAT

1. Noida Institute of Engineering and Technology
(Pharmacy Institute) Greater Noida
ANIMALS USED IN EXPERIMENTAL
PHARMACOLOGY
CAT
BY HARSH PRATAP SINGH
M. PHARM ( PHARMACOLOGY)
IN THE GUIDENCE OF DR.SAUMYA DAS
(ASSOCIATE PROFESSOR)

2. CONTENT
• INTRODUCTION
• CHARACTERISTICS
• ANATOMY OF MALE DOMESTIC CAT
• LIFESPAN
• EXPERIMENTAL USE
• DIET AND HEALTH
• HOUSING
• FACTS

3. CAT
• The scientific name Felis catus was
proposed by Carl Linnaeus in 1758 that
belongs to the Felidae (feline) family.
• They are the smallest member of the
feline family.
• The behavioral psychologist Edward
Thorndike cat-based learning
expereiment in the late 1800s.

4. CHARACTERISTICS
• The domestic cat has a smaller skull and shorter bones.
• It about 46 cm (18 in) in head-to-body length and 23–25 cm (9–10 in) in height, with
30 cm (12 in) long tails.
• Males are larger than females.
• Adult domestic cats weigh between 4 and 5 kg (9 and 11 lb).
• The cat has a highly developed nictitating membrane.
• In cats, morphine produces excitation of the CNS.

5. ANATOMY OF A MALE DOMESTIC CAT

6. LIFESPAN
• In the 1980s, its about seven years,
rising to 9.4 years in 1995 and then 15
years in 2021.
• Some cats have been reported as
surviving into their 30s, with the oldest
known cat, Creme Puff, dying at a
verified age of 38.
• The average birth weight of a domestic
cat is 3 ounces.

7. EXPERIMENTAL USE
• The study of drugs affecting blood
pressure.
• Anesthetized and spinal preparations are
used for the assay of catecholamines.
• Contractions of the nictitating membrane
are recorded for the investigation of
ganglionic blocking action of the drugs.
• Cats are excellent animal model for
diseases such as leukemia, Alzheimer's
disease, heart disease, infection, and
immunodeficiency.

8. DIET AND HEALTH
• Cats are carnivores.
• Mostly animal flesh is their diet,
and they have a stomach capable
of digesting raw meat.
• Their is the occasional hunting
activities of the cat to support their
diet, is typically dependent on
their human owners.

9. HOUSING
• Caging Design and Operating Procedures
• Animal Care Staff
Animal care staff working with cats and be willing to interact with them to assure socialization
and tractability.
• Feline Social Behavior
As natural predators, cats possess keen senses and heightened fight-or-flight responses, making
them particularly susceptible to environmental stress
• Housing to Exclude Pathogens
• Environmental Enrichment

11. REFERENCES
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Models for Tissue Engineering: Reflections on Legal Aspects, Moral Theory, Three Rs Strategies, and Harm-
Benefit Analysis. Tissue Eng Part C Methods. 2017; 23(12):850-62.
• Banerjee D, Tripathi M. Laws and regulations regarding animal experimentation in India. I pleaders. By Rachit
Garg. 2020 September 12.
• Hansen LA, Kosberg KA. Ethics, Efficacy, and Decision-making in Animal Research. InAnimal
Experimentation: Working towards a Paradigm Change. Brill, 2019 Apr 17:275-88.
• Bates AW. Vivisection, Virtue, and the Law in the Nineteenth Century. InAnti-Vivisection and the Profession of
Medicine in Britain. Palgrave Macmillan, London, 2017:13-41.
• Singh VP, Pratap K, Sinha J, Desiraju K, Bahal D, Kukreti R. Critical evaluation of challenges and future use of
animals in experimentation for biomedical research. Int J Immunopathol Pharmacol. 2016 Dec;29(4):551-61.