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SEPTIC ARTHRITIS
Dr. Sumeet Jadhav
JR2/Dr. S. K. S. Unit
Department of Orthopaedics
INTRODUCTION
• Pathological joint space invasion
by microbes followed by
inflammation
OR
• Inflammation of synovial
membrane due to infection
which results in purulent
effusion in joint capsule
ETIOLOGY
HEMATOGENOUS
(MOST COMMON)
SECONDARY TO
NEARBY
OSTEOMYELITIS
PENETRATING
WOUND
IATROGENIC
E.g. INTRARTICULAR
STEROID INJECTION OR
FEMORAL BLOOD
COLLECTION
Ogranism can gain
entry into joint by any
of the following route
SPREAD OF INFECTION TO JOINT CAPSULE
INFLAMMATORY REACTION WITH SEROPURULENT EXUDATE
INCREASE IN SYNOVIAL FLUID
ARTICULAR CARTILAGE IS ERODED AND
DESTROYED
CAUSATIVE MICROORGANISM
STAPH. AUREUS (MC)
NEONATES AND YOUNGER INFANTS GROUP B STREPTOCOCCI AND GRAM NEGATIVE
ENTERIC BACILLI
SEXUALLY ACTIVE ADOLESCENTS AND ADULTS N. GONORRHOEA
IV DRUG ABUSER, IMMUNOCOMPRAMISED GRAM NEGATIVE BACILLI LIKE E. COLI AND
PSEUDOMONAS
SICKLE CELL ANEMIA SALMONELLA
PROSTHETIC JOINT RECEIPIENTS CoNS E. g. STAPH EPIDERMIS
POLYARTICULAR STAPHYLOCOCCUS > STREPTOCOCCI GROUP G
OTHER M. TUBERCULOSIS
CAUSATIVE MICROORGANISM
• VIRAL: HEPATITIS A,B,C
HERPES VIRUS
MUMPS
• FUNGAL: CISTOPLASMA
COCCIDIODES
BLASTOMYCOSIS
CLINICAL FEATURES
INFANT
FEATURES OF SEPTICEMIA ARE MORE AS
COMPARED TO JOINT PAIN
JOINT IS WARMTH, RESISTANT TO
MOVEMENT, TENDERNESS
CHILDREN
MONOARTICULAR
REDNESS AND SUPERFICIAL JOINT
SWELLING VISIBLE
LOCAL WARMTH AND TENDERNESS
RESTRICTION OF MOVEMENTS
CLINICAL FEATURES
ADULTS
• JOINT IS PAINFUL, SWOLLEN AND INFLAMED
• DECREASED ABILITY TO MOVE THE JOINT
• SYSTEMIC SYMPTOMS LIKE FEVER WITH CHILLS,
MALAISE, POOR APPETITE, IRRITABILITY
• SUPERFICIAL JOINTS ARE AFFECTED MORE
DIAGNOSTIC TRIAD
PAINFUL
JOINT
LIMITATION
ELEVATED ESR
HIGH GRADE
FEVER WITH
RIGOR
KOCHER’S CRITERIA
VARIABLE INCLUDES
1. NON WEIGHT BEARING ON AFFECTED SIDE
2. ERYTHROCYTE SEDIMENTATION RATE > 40
3. FEVER > 38.5 C
4. WHITE BLOOD CELL COUNT > 12000
SCORE LIKELIHOOD OF SEPTIC ARTHRITIS
1 3 %
2 40 %
3 93 %
4 99%
TOM SMITH ARTHRITIS
• SEPTIC ARTHRITIS OF HIP IN INFANCY
• HEAD OF FEMUR IS RAPIDLY DESTROYED BY PYOGENIC PROCESS.
• CAUSE:
- METAPHYSIS IS INTRASYNOVIAL
- PRESENCE OF TRANSEPIPHYSEAL VESSEL IN CHILDREN TILL THE AGE OF 18 MONTHS
• PATHOPHYSIOOGY
- INCREASED INTRAARTIULAR PRESSURE
- DIRECT DESTRUCTIVE ACTION OF PUS ON ARTICULAR CARTILAGE
- ISCHEMIA TO GROWTH PLATE DUE TO THROMBOSIS ON THE BOTH SIDE OF THE PLATE
• TREATMENT
- AS SOON AS PUS IS ASPIRATED, DRAINAGE OF JOINT TO PREVENT DAMAGE TO HIP
- RECONSTRUCTIVE HIP PROCEDURE PLANNED LATER
TUBERCULAR ARTHRITIS
• LESS COMMON
• IT CAN RESULT FROM
1. Actual infection from M. Tuberculosis which
presents as monoarticular infection
2. From an allergic phenomenon which present as
polyarthritis.
INVESTIGATIONS
1. X RAY
NON SPECIFIC
INITIAL STAGE- X RAY ARE NORMAL, GROUND GLASS APPEARANCE
WITH LOSS OF SOFT TISSUE PLANES SEEN
INVESTIGATIONS
• LATER STAGE – JOINT SPACE NARROWING
2. USG
• More reliable
• It can diagnose joint effusion in early stages.
• Detects effusion and pus in joint with synovial thickening.
• It can identify plane of collection so that we can differentiate it from
cellulitis and bursitis.
• ECHO FREE – TRANSIENT SYNOVITIS
• POSITIVE ECHOGENICITY – SEPTIC ARTHRITIS
3. SYNOVIAL FLUID ANALYSIS
• NORMAL: HIGH VISCOUS, COLOURLESS, TRANSPARENT
• SEPTIC ARTHITIS:
GROSS : HIGH VISCOSITY AND COLOUR YELLOW OR STROW YELLOW,
OPAQUE
LAB EXAMINATION: WBC COUNT INCREASES,
CULTURE MAY BE POSITIVE
SUGAR LEVEL REDUCED
TREATMENT
• SPLINTAGE
The joint must be held in most comfortable position either on splint or
plaster
• GENERAL CARE
Analgesics and iv fluids
ANTIBIOTICS
Once the samples are obtained, antibiotics should be started without
without waiting for result
Later they should be changed as per the final report
NEISSERIA (GRAM NEGATIVE DIPLOCOCCI) CEFTRIAXONE
MSSA CEFTRIAXONE
MRSA VANCOMYCIN OR CLINDAMYCINE OR LINEZOLID
STREPTOCOCCUS CEFTRIAXONE
E. COLI, PROTEUS, SERRATIA PIPTAZ
CEFTAZIDIME
PROSTHESIS RELATED (CoNS) THIRD GENERATION CEPHALOSPORIN + VANCOMYCIN
TREATMENT
• SURGICAL MANAGEMENT
IMMEDIATE DEBRIDEMENT FOLLOWED BY IRRIGATION WITH NORMAL
SALINE
CAN BE DONE ARTHROSCOPICALLY
COMPLICATION
• DEFORMITY AND STIFFNESS
JOINT GETS STIFF DUE TO INTRARTICULAR OR PERIARTICULAR
ADHESION
• OSTEOARTHRITIS
GENERALLY PRESENT LATE
COMPLICATIONS
• PATHOLOGIAL DISLOCATION
INFLAMMATORY EXUDATES IN JOINTS INDUCES STRESS IN SUPPORTIVE
LIGAMENTS.
MUSCLE SPASM ASSOCIATED WITH DISEASE LEADS TO PATHOLOGICAL
DISLOCATION
COMPLICATION
• POSTERIOR DISLOCATION OF HIP
COMPLICATIONS
• TRIPPLE DEFORMITY OF KNEE
THANK YOU

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Septic arthritis

  • 1. SEPTIC ARTHRITIS Dr. Sumeet Jadhav JR2/Dr. S. K. S. Unit Department of Orthopaedics
  • 2. INTRODUCTION • Pathological joint space invasion by microbes followed by inflammation OR • Inflammation of synovial membrane due to infection which results in purulent effusion in joint capsule
  • 3. ETIOLOGY HEMATOGENOUS (MOST COMMON) SECONDARY TO NEARBY OSTEOMYELITIS PENETRATING WOUND IATROGENIC E.g. INTRARTICULAR STEROID INJECTION OR FEMORAL BLOOD COLLECTION Ogranism can gain entry into joint by any of the following route
  • 4. SPREAD OF INFECTION TO JOINT CAPSULE INFLAMMATORY REACTION WITH SEROPURULENT EXUDATE INCREASE IN SYNOVIAL FLUID ARTICULAR CARTILAGE IS ERODED AND DESTROYED
  • 5.
  • 6. CAUSATIVE MICROORGANISM STAPH. AUREUS (MC) NEONATES AND YOUNGER INFANTS GROUP B STREPTOCOCCI AND GRAM NEGATIVE ENTERIC BACILLI SEXUALLY ACTIVE ADOLESCENTS AND ADULTS N. GONORRHOEA IV DRUG ABUSER, IMMUNOCOMPRAMISED GRAM NEGATIVE BACILLI LIKE E. COLI AND PSEUDOMONAS SICKLE CELL ANEMIA SALMONELLA PROSTHETIC JOINT RECEIPIENTS CoNS E. g. STAPH EPIDERMIS POLYARTICULAR STAPHYLOCOCCUS > STREPTOCOCCI GROUP G OTHER M. TUBERCULOSIS
  • 7. CAUSATIVE MICROORGANISM • VIRAL: HEPATITIS A,B,C HERPES VIRUS MUMPS • FUNGAL: CISTOPLASMA COCCIDIODES BLASTOMYCOSIS
  • 8. CLINICAL FEATURES INFANT FEATURES OF SEPTICEMIA ARE MORE AS COMPARED TO JOINT PAIN JOINT IS WARMTH, RESISTANT TO MOVEMENT, TENDERNESS CHILDREN MONOARTICULAR REDNESS AND SUPERFICIAL JOINT SWELLING VISIBLE LOCAL WARMTH AND TENDERNESS RESTRICTION OF MOVEMENTS
  • 9. CLINICAL FEATURES ADULTS • JOINT IS PAINFUL, SWOLLEN AND INFLAMED • DECREASED ABILITY TO MOVE THE JOINT • SYSTEMIC SYMPTOMS LIKE FEVER WITH CHILLS, MALAISE, POOR APPETITE, IRRITABILITY • SUPERFICIAL JOINTS ARE AFFECTED MORE
  • 11. KOCHER’S CRITERIA VARIABLE INCLUDES 1. NON WEIGHT BEARING ON AFFECTED SIDE 2. ERYTHROCYTE SEDIMENTATION RATE > 40 3. FEVER > 38.5 C 4. WHITE BLOOD CELL COUNT > 12000 SCORE LIKELIHOOD OF SEPTIC ARTHRITIS 1 3 % 2 40 % 3 93 % 4 99%
  • 12. TOM SMITH ARTHRITIS • SEPTIC ARTHRITIS OF HIP IN INFANCY • HEAD OF FEMUR IS RAPIDLY DESTROYED BY PYOGENIC PROCESS. • CAUSE: - METAPHYSIS IS INTRASYNOVIAL - PRESENCE OF TRANSEPIPHYSEAL VESSEL IN CHILDREN TILL THE AGE OF 18 MONTHS • PATHOPHYSIOOGY - INCREASED INTRAARTIULAR PRESSURE - DIRECT DESTRUCTIVE ACTION OF PUS ON ARTICULAR CARTILAGE - ISCHEMIA TO GROWTH PLATE DUE TO THROMBOSIS ON THE BOTH SIDE OF THE PLATE • TREATMENT - AS SOON AS PUS IS ASPIRATED, DRAINAGE OF JOINT TO PREVENT DAMAGE TO HIP - RECONSTRUCTIVE HIP PROCEDURE PLANNED LATER
  • 13. TUBERCULAR ARTHRITIS • LESS COMMON • IT CAN RESULT FROM 1. Actual infection from M. Tuberculosis which presents as monoarticular infection 2. From an allergic phenomenon which present as polyarthritis.
  • 14. INVESTIGATIONS 1. X RAY NON SPECIFIC INITIAL STAGE- X RAY ARE NORMAL, GROUND GLASS APPEARANCE WITH LOSS OF SOFT TISSUE PLANES SEEN
  • 15. INVESTIGATIONS • LATER STAGE – JOINT SPACE NARROWING
  • 16. 2. USG • More reliable • It can diagnose joint effusion in early stages. • Detects effusion and pus in joint with synovial thickening. • It can identify plane of collection so that we can differentiate it from cellulitis and bursitis. • ECHO FREE – TRANSIENT SYNOVITIS • POSITIVE ECHOGENICITY – SEPTIC ARTHRITIS
  • 17. 3. SYNOVIAL FLUID ANALYSIS • NORMAL: HIGH VISCOUS, COLOURLESS, TRANSPARENT • SEPTIC ARTHITIS: GROSS : HIGH VISCOSITY AND COLOUR YELLOW OR STROW YELLOW, OPAQUE LAB EXAMINATION: WBC COUNT INCREASES, CULTURE MAY BE POSITIVE SUGAR LEVEL REDUCED
  • 18. TREATMENT • SPLINTAGE The joint must be held in most comfortable position either on splint or plaster • GENERAL CARE Analgesics and iv fluids
  • 19. ANTIBIOTICS Once the samples are obtained, antibiotics should be started without without waiting for result Later they should be changed as per the final report NEISSERIA (GRAM NEGATIVE DIPLOCOCCI) CEFTRIAXONE MSSA CEFTRIAXONE MRSA VANCOMYCIN OR CLINDAMYCINE OR LINEZOLID STREPTOCOCCUS CEFTRIAXONE E. COLI, PROTEUS, SERRATIA PIPTAZ CEFTAZIDIME PROSTHESIS RELATED (CoNS) THIRD GENERATION CEPHALOSPORIN + VANCOMYCIN
  • 20. TREATMENT • SURGICAL MANAGEMENT IMMEDIATE DEBRIDEMENT FOLLOWED BY IRRIGATION WITH NORMAL SALINE CAN BE DONE ARTHROSCOPICALLY
  • 21. COMPLICATION • DEFORMITY AND STIFFNESS JOINT GETS STIFF DUE TO INTRARTICULAR OR PERIARTICULAR ADHESION • OSTEOARTHRITIS GENERALLY PRESENT LATE
  • 22. COMPLICATIONS • PATHOLOGIAL DISLOCATION INFLAMMATORY EXUDATES IN JOINTS INDUCES STRESS IN SUPPORTIVE LIGAMENTS. MUSCLE SPASM ASSOCIATED WITH DISEASE LEADS TO PATHOLOGICAL DISLOCATION