SlideShare a Scribd company logo
1 of 35
II Pharm . D
REG NO :
381710525.
2018-2019.
1
2
3
A 51 year old man was admitted in our KMCH hospital on 23/7/19 as
secondary treatment due to accident in two wheeler on 16/7/19. He was
treated in primary set up on 16/7/19 ICD on both sides and ORIF were done
@palani .HRCT revealed the hydropneumothorax on the right side of the
lung &bronchopleural fistula then numerous bone fractures on the lower
limb. Bronchoscopy and thoracoscopic guided glue injection was planned
for to prevent the air leak in the lungs on 26/7/19.
4
 REG NO: 1547418.
 IP NO: F08833.
 AGE & SEX: 51 years old male.
 MARRITAL STATUS: Married.
 DATE OF ADMISSION: 23/7/19 @8:42am.
 DATE OF DISCHARGE: 31/7/19 @2:50pm.
 PRIMARY CONSULTANTS: Dr. Santha kumar (pulmonologist) &
Dr. DMI. Saravana (cardiologist).
 RTA : 2wheeler vs 2wheeler on 16/7/19 primarily treated in native place.
5
 Present diagnosis: Rt. Hydropneumothorax.
 Previous procedure surgery: ICD ORIF Done on 16/7/19.
 Provisional diagnosis: COPD & bronchopleural fistula.
 Multiple conditions :
Rt. Intertrochanteric fracture (ORIF).
Rt. Metatarsal fracture.
Flial chest.
 Procedure’s undergone: (previous)
Rt. ICD persistent air leak .
Lt. ICD removed.
6
7
ORIF: open reduction internal fixation.
Internal plates(internal splints)
and screws were placed.
8
Social history: smoker & alcoholic.
Past history : No comorbidities.
Family history: No comorbidities.
Drug allergy : No history of known drug allergy.
1 pack year= 1/2pack/day X 1 yr
= 10 cigarettes/1/2pack
=10X 365.24packs
= 3652.4cigarettes.
9
Suggested to perform:
ABG ,CBC, ESR, Urea ,Creatinine, Na+, K+, HRCT, RBS,
HIV- ELISA, PT/INR, ECHO.
ECHO report:
 No regional wall motion abnormality.
Normal LV systolic function.
Trivial mitral regurgitation.
Mild and Moderate pulmonary arterial hypertension(RVSP- 50mmHg).
Inferior vena cava 1.9cm dilated.
No pulmonary embolism/clot.
10
11
contents 23/7/19 24/7/19 25/7/19 26/7/19 27/7/19 28/7/19 29/7/19 30/7/19
Hb 7.8g/dL 7.4g/dL 7.6g/dL 7.6g/dL 7.8g/dL 8.4g/dL 8.6g/dL 8.4g/dL
Tc(cells/cumm) 13900cells/cumm.
Total RBC ↓2.62million/mm3
DC P
L
E
B
M
↑74%
↓21%
02%
00%
03%
PCV ↓22.6%
MCV 86.4fL
MCH 29.9pg/cell.
MCHC 34.6g/dL
ESR(mm/hr) ↑76mm/hr
Platelet 363000cells/µl
Urea -
creatinine 0.5mg/dL
12
content 23/7/19
Sodium 137mEq/L
Potassium 4.8mEq/L
HIV Negative
Blood group &Rh typing O+
Prothrombin Pt value -16.
Control -12 sec.
INR -1.43.
DATE TIME HR(beats/min) RR(breaths/min) BP (mmHg) %SpO2(with O2)
23/7/19 12:50am
6:00pm
10pm
92(beats/min)
96(beats/min)
98(beats/min)
24 (breaths/min)
22(breaths/min)
26(breaths/min)
100/90(mmHg)
130/80(mmHg)
130/90(mmHg)
100
99
97
24/7/19 6am
10pm
2pm
6pm
10pm
82(beats/min)
102(beats/min)
100(beats/min)
108(beats/min)
112(beats/min)
22(breaths/min)
24(breaths/min)
24(breaths/min)
22(breaths/min)
26(breaths/min)
110/60(mmHg)
100/60(mmHg)
100/80(mmHg)
120/70(mmHg)
120/80(mmHg)
97
96
97
98
98
25/7/19 2am
6am
10am
2pm
6pm
10pm
116(beats/min)
100(beats/min)
114(beats/min)
120(beats/min)
112(beats/min)
100(beats/min)
28(breaths/min)
26(breaths/min)
22(breaths/min)
22(breaths/min)
20(breaths/min)
20(breaths/min)
130/90(mmHg)
130/80(mmHg)
120/70(mmHg)
130/90(mmHg)
130/80(mmHg)
110/60(mmHg)
96
97
98
97
98
99
26/7/19 6am
5pm
6pm
7pm
8pm
9pm
10pm
92(beats/min)
86(beats/min)
88(beats/min)
82(beats/min)
84(beats/min)
86(beats/min)
82(beats/min)
24(breaths/min)
22(breaths/min)
22(breaths/min)
20(breaths/min)
20(breaths/min)
22(breaths/min)
20(breaths/min)
120/80(mmHg)
110/80(mmHg)
120/70(mmHg)
110/60(mmHg)
120/80(mmHg)
110/60(mmHg)
120/80(mmHg)
99
100
100
98
99
98
97 13
14
DATE TIME HR(beats/min) RR(breaths/min) BP(mmHg) %SpO2
27/7/19 6am
10am
2pm
6pm
10pm
100(beats/min)
102(beats/min)
100(beats/min)
104(beats/min)
100(beats/min)
26(breaths/min)
22(breaths/min)
20(breaths/min)
22(breaths/min)
24(breaths/min)
110/60(mmHg)
110/70(mmHg)
100/80(mmHg)
110/70(mmHg)
120/80(mmHg)
97%
92%
91%
91%
97%
28/7/19 6am
10am
2pm
6pm
10pm
98(beats/min)
112(beats/min)
106(beats/min)
100(beats/min)
94(beats/min)
22(breaths/min)
22(breaths/min)
24(breaths/min)
22(breaths/min)
22(breaths/min)
110/60(mmHg)
110/80(mmHg)
120/80(mmHg)
110/70(mmHg)
110/70(mmHg)
98%
96%
96%
97%
97%
29/7/19 6am
10am
2pm
6pm
10pm
116(beats/min)
112(beats/min)
112(beats/min)
110(beats/min)
108(beats/min)
22(breaths/min)
22(breaths/min)
22(breaths/min)
22(breaths/min)
22(breaths/min)
110/70(mmHg)
110/70(mmHg)
110/80(mmHg)
110/70(mmHg)
110/70(mmHg)
100%
96%
96%
97%
98%
30/7/19 6am
10am
2:30pm
6pm
10pm
102(beats/min)
114(beats/min)
116(beats/min)
102(beats/min)
84(beats/min)
22(breaths/min)
24(breaths/min)
26(breaths/min)
24(breaths/min)
20(breaths/min)
130/60(mmHg)
100/70(mmHg)
110/70(mmHg)
120/80(mmHg)
110/70(mmHg)
99%
98%
97%
98%
98%
15
DATE TIME HR(beats/min) RR(breaths/min) BP(mmHg) %SpO2
31/7/19 6am
10am
72(beats/min)
120(beats/min)
20(breaths/min)
22(breaths/min)
110/60(mmHg)
100/70(mmHg)
98%
97%
On 23/7/19 @ 8:42am patient admitted in kmch hospital
@11:52am patient history was noted as
 Tachypnoeic . HR: 94beats/min
 ICD Insitu Rt side. RR: 24breaths/min
 S1 S2 heard. SpO2: 100%
 Pulse rate 90. Temp: 100.5F
 BP 140/90mmHg. GRBS: 99mg/dl
 Hb-7.8g/dl.
Provisional diagnosis: Rt. Bronchopleural fistula.
Plan :
 Inj. Zosyn 4.5gm IV 8hrly infusion over 30mins.
Neb. Levolin 0.63 4hrly respules.
Neb. Formonide 0.5mg BD.
Incentive spirometry.
Tab. P650 BD & Inj. Heparin 5000units S/C OD.
16
17
18
On 23/7/19 @3:20pm
Multiple rib fractures
 Right 3rd-10th&left 2nd-6th.
 Right intertrochanteric fracture.
 Right bimalleolar fracture.
 Right 4th proximal phalanx
Surgery done outside on 16/7/19.
Post operative physiotherapy given.
ECG: satisfactory cardiac status.
@5:00pm Dr. santha kumar
patient reviewed : Hb = 7.8g/dL.
PLAN:
Syp. Dexorange 10ml BD.
To do B/L lower limb venous doppler.
inj. Clexane 0.4 S/C BD.
(heparin was stopped)
inj. Tramadol 50mg IV BD.
inj. Emeset 4mg IV BD.
inj. Paracetamol 1gm IV TID
Daily to check Hb.
HRCT Scan of lungs:
 moderate right hydropneumothorax.
Left moderate pleural effusion.
Patchy and confluent ground glassing is noted in the bilateral lung fields.
Fractures as detailed.
Doppler study of left lower limb veins:
No evidence of deep venous thrombosis.
19
20
 The patient was diagnosed with hydropneumothorax by the HRCT scan
evidence report.
 The patients ESR was found to be moderately high 76mm/Hr.
 The patients Total RBC count was extremely low to 2.62million/µL
(hemolysis).
 It can be due to accident blood loss and blood vessel injury and bone
marrow damage can also leads to this deadly conditions.
 https://www.medicalnewstoday.com
21
Hydropneumothorax is treated by
ICD and bronchoscopy with glue injection .
22
On 23/7/19 @12: 50pm
 Temp: 98.6F
 Pulse: 92/min
 RR : 24/min
 SpO2: 100%
 BP: 140/90mmHg.
 Pain persists
Total intake = 750ml
Total output= 2300ml
 On 24/7/19 @ 8:55am patient reviewed Plan on 23/7/19:
 Traumatic B/L pneumothorax . Inj. Para 1gram IV
 Right bronchopleural fluid ,flial chest. Inj. Augmentin 1.2 gram IV
 Right hydropneumothorax. Inj. Pan 40mg IV
BP dropped to 110/60. Inj. Emeset 4gram IV
HR dropped to 82beats/min.
RR dropped to 22breaths/min. Total intake = 850ml
%SpO2 is 97% & Temp 98.8F. Total output = 1900ml
Complaint of difficulty in breathing.
Cough with expectoration.
On 25th @ 8:45am
 Temp: 99bts/min
 HR: 100bts/min
 RR: 26breaths/min
BP: 130/80mmHg.
%SpO2: 97% with 5 litres of oxygen.
Complaints of : cough with expectoration & difficulty in breathing.
PLAN: D3
 Inj. Zosyn
Inj. Clexane
Neb. Levolin
Neb. Formonide
Syp. Dexorange.
Inj. Tramadol.
Plan for bronchoscopy tomorrow@ 9: 30
incentive spirometry
@4:45pm
inj. Ketorolac 3mg IV in 100ml NS (BD).
23
 Under general anaesthesia
bronchoscopy and thoracoscopic for BPF was done.
0.5ml of glue in each segment is injected.
NPO till 4pm. & monitoring vitals every 15mins till 4pm.
To send drain fluid for Antibiotic susceptibility test for bacterial presence of culture detection.
D4 inj. Zosyn
Neb. Levolin continue till 4pm.
Total intake = 900ml
Drain=100ml
Urine=2500ml
Total output = 2600ml.
On 27/7/19 @9:50 am
Patient is feeling better Air leak has been decreased.
Mobilise out of bed ,incentive spirometry ,Stop ketorolac ,restart inj.clexane & high protein diet.
24
25
On 29/7/19 @ 8:45am
complaint of pain at the site of ICD
Not passed stools since 6 days.
Rt. ICD =30ml. No air leak.
On 30/7/19 @ 12:30pm
ICD removed with strict aseptic condition.
PLAN:
Tab. Chymoral forte (TID)
Tab. Myoril 8mg (BD)
On 31/7/19 @8:10am
Minimal pain @ICD site & patient mobilized.
stat dulcoflex 2dose @12pm rectal route.
26
 To reduce the pain .
 To reduce the risk and comorbidities.
 To improve the breathing trouble .
 To increase the red blood cell count.
 To prevent from infection.
 To make the patient mobilise cost effectively.
27
28
29
DRUG DOSE ROUTE &
FREQUENCY
TIME START DATE END DATE
Inj. Zosyn 4.5gm IV & TID 2am
10am
6pm 23/7
31/7@6am
Neb. Formonide 0.5mg Inhalation & BD 6am
6pm 23/7
31/7@6am
Tab. P.650 650mg Oral & BD 9am
9pm
23/7@2pm 23/7dose &Route
Changed
Inj. Para 1gm IV & TID 6am
2pm
10pm 23/7
31/7@6am
Inj. Heparin 5000units IV & OD 10am 23/7 23/7
Inj. Clexane 0.4mg S/C & BD 11am
11pm 23/7
24/7
Changed as OD
Inj. Clexane 0.4mg S/C & OD 11am 24/7 31/7@11am
DRUG CHART:
30
DRUG DOSE ROUTE &
FREQUENCY
TIME START DATE END DATE
Neb. Levolin 0.63mg Inhalation & Q4H 2am
6am
10am
2pm
6pm
10pm
23/7
31/7@10am
Prosure protein powder 2tsp Oral & OD 6am 23/7@7pm 27/7 frequency changed
to BD
Syp. Dexorange 10ml Oral & BD 9am
9pm 23/7
31/7@9am
Inj. Emeset 4mg IV & BD 6am
6pm 23/7
31/7@6am
Inj. Tramadol 50mg IV & BD 6am
6pm 23/7
31/7@6am
Inj. Ketoral 30mg IV & BD 8am
8pm 25/7
27/7@8am
Tab. Chymoral forted’s - Oral & TID 9am
2pm
10pm 30/7
31/7@9am
31
C:UsersSRI SHARIKA KUMARDownloadsInhaled corticosteroids plus long-
acting beta2-agonists as a combined therapy in asthma. - PubMed - NCBI.mhtml
PHARMACIST RECOMMENDATION:
https://www.ncbi.nlm.nih.gov/m/pubmed/27877033/
 There is no serious drug- drug , drug-food, drug-disease interaction.
 MILD AND FAIR RELIABILITY:
 Ondansetron will decrease the absorption of tramadol.
 Ondansetron will decrease the absorption of acetaminophen.
 Enaxoparin and Toradol administration cause enhanced effect of anticoagulant
property of enaxoparin.
PHARMACIST RECOMMENDATION:
Tramadol is an centrally acting analgesic also triggers the chemoreceptor trigger zone
so that patient have a chance to vomit , so to avoid that aceclofenac and paracetamol
combination or diclofenac combination can be used.
Antiemetics can be omitted from the treatment chart.
http://apm.amegroups.com/article/view/1038/1264
32
 What to avoid ? Don’t s
 smoking should be strictly
avoided.
Not to lift more than 3.5kgs
until the fractured bones get
heal.
No heavy physical activity.
 Does:
Take all the prescribed medications without fail.
Take good rest.
Use the spacer and inhaler
as instructed .
Gargle after use of spacers.
 DRUG DETAILS:
Tab. Pan 40mg- should be taken before food.
2hours gap should be given while taking Tab. Pan
& Tab. Cefakind CV 625mg.
Gap of 2mins should be given between the puffs of
spacer.
33
stable discharge on 31/7/19@2:50pm (spirometry to continue)
34
Medications Dosage Morning Afternoon Evening Night A/B Food Duration
Tab. Ultracet 37.5mg/325mg 1 0 0 1 AF 1 week
MDI Formonide
via spacer
200 2puffs 0 0 2puffs 1 week
Prosure protein
powder
2scoops in Water Once a day 1 week
Tab. Cefakind
CV
625mg 1 1 0 1 AF 1 week
Tab. Pan 40mg 1 0 0 0 BF 1 week
MDI Levolin 0.5mcg 2puffs 2puffs 0 2puffs 1 week
Syp. Dexorange 10ml 0 0 10ml 1 week
35
 Before the second puff
Give 2mins gap.
 Atlast gargling is necessary to
avoid fungal mouth infections.

More Related Content

What's hot

Respiratory examination
Respiratory examinationRespiratory examination
Respiratory examinationcardilogy
 
Interstitial Lung Disease
Interstitial Lung DiseaseInterstitial Lung Disease
Interstitial Lung DiseaseKamal Bharathi
 
Pulmonary edema
Pulmonary edemaPulmonary edema
Pulmonary edemaAmna Akram
 
Pulmonary fibrosis
Pulmonary fibrosis   Pulmonary fibrosis
Pulmonary fibrosis Ardra Kurian
 
Pneumothorax case presentation
Pneumothorax case presentationPneumothorax case presentation
Pneumothorax case presentationDr. Ashish kumar
 
Approach to Chest X-Ray and Interpretation
Approach to Chest X-Ray and InterpretationApproach to Chest X-Ray and Interpretation
Approach to Chest X-Ray and InterpretationVikram Patil
 
Complications of pulmonary tb
Complications of pulmonary tbComplications of pulmonary tb
Complications of pulmonary tbAnkur Gupta
 
Pulmonary Function Test
Pulmonary Function TestPulmonary Function Test
Pulmonary Function TestRahul Ap
 
Case Presentation On Respiratory Medicine
Case Presentation On Respiratory MedicineCase Presentation On Respiratory Medicine
Case Presentation On Respiratory Medicinedrtanoybose
 
History taking and general examination of respiratory system
History taking and general examination of respiratory systemHistory taking and general examination of respiratory system
History taking and general examination of respiratory systemHimanshu Rana
 
Local chest examination
Local chest examinationLocal chest examination
Local chest examinationimangalal
 
Approach to a patient with Haemoptysis
Approach to a patient with HaemoptysisApproach to a patient with Haemoptysis
Approach to a patient with HaemoptysisKhairul Jessy
 

What's hot (20)

Respiratory examination
Respiratory examinationRespiratory examination
Respiratory examination
 
Approach to Lung sounds
Approach to Lung soundsApproach to Lung sounds
Approach to Lung sounds
 
Hemothorax
HemothoraxHemothorax
Hemothorax
 
Chest Wall Deformity
Chest Wall DeformityChest Wall Deformity
Chest Wall Deformity
 
Interstitial Lung Disease
Interstitial Lung DiseaseInterstitial Lung Disease
Interstitial Lung Disease
 
Pulmonary edema
Pulmonary edemaPulmonary edema
Pulmonary edema
 
Clubbing
ClubbingClubbing
Clubbing
 
Pulmonary fibrosis
Pulmonary fibrosis   Pulmonary fibrosis
Pulmonary fibrosis
 
Pneumothorax case presentation
Pneumothorax case presentationPneumothorax case presentation
Pneumothorax case presentation
 
Flail chest
Flail chestFlail chest
Flail chest
 
Clubbing
ClubbingClubbing
Clubbing
 
Approach to Chest X-Ray and Interpretation
Approach to Chest X-Ray and InterpretationApproach to Chest X-Ray and Interpretation
Approach to Chest X-Ray and Interpretation
 
Case presentation (COPD)
Case presentation (COPD)Case presentation (COPD)
Case presentation (COPD)
 
Hemoptysis
HemoptysisHemoptysis
Hemoptysis
 
Complications of pulmonary tb
Complications of pulmonary tbComplications of pulmonary tb
Complications of pulmonary tb
 
Pulmonary Function Test
Pulmonary Function TestPulmonary Function Test
Pulmonary Function Test
 
Case Presentation On Respiratory Medicine
Case Presentation On Respiratory MedicineCase Presentation On Respiratory Medicine
Case Presentation On Respiratory Medicine
 
History taking and general examination of respiratory system
History taking and general examination of respiratory systemHistory taking and general examination of respiratory system
History taking and general examination of respiratory system
 
Local chest examination
Local chest examinationLocal chest examination
Local chest examination
 
Approach to a patient with Haemoptysis
Approach to a patient with HaemoptysisApproach to a patient with Haemoptysis
Approach to a patient with Haemoptysis
 

Similar to II Pharm. D Bronchopleural Fistula Case

Slide materi webinar 28 juni 2020
Slide materi webinar 28 juni 2020Slide materi webinar 28 juni 2020
Slide materi webinar 28 juni 2020EkaPratiwi69
 
Case presentation on multinodular goiter
Case presentation on multinodular goiterCase presentation on multinodular goiter
Case presentation on multinodular goiterSrisharikakumar
 
Myocardial infraction by satyavardhan pharm.d
Myocardial infraction by satyavardhan pharm.dMyocardial infraction by satyavardhan pharm.d
Myocardial infraction by satyavardhan pharm.dSatya satyanittu4
 
MODIFIED FILE.pptx
MODIFIED FILE.pptxMODIFIED FILE.pptx
MODIFIED FILE.pptxbikashd1
 
ED John Budd a 72yearold arrived in the emergency depa.pdf
ED  John Budd a 72yearold arrived in the emergency depa.pdfED  John Budd a 72yearold arrived in the emergency depa.pdf
ED John Budd a 72yearold arrived in the emergency depa.pdfabhishekcctv
 
LAST SEPT MORTALITY MEET 1.pptx
LAST SEPT MORTALITY MEET 1.pptxLAST SEPT MORTALITY MEET 1.pptx
LAST SEPT MORTALITY MEET 1.pptxbikashd1
 
MORTALITY AND MORBIDITY.pptx
MORTALITY AND MORBIDITY.pptxMORTALITY AND MORBIDITY.pptx
MORTALITY AND MORBIDITY.pptxAnisSalman
 
ED John Budd a 72yearold arrived in the emergency depa.pdf
ED  John Budd a 72yearold arrived in the emergency depa.pdfED  John Budd a 72yearold arrived in the emergency depa.pdf
ED John Budd a 72yearold arrived in the emergency depa.pdfinfo878313
 
CLINICAL CASE DISCUSSION ON community acquired pneumonia
CLINICAL CASE DISCUSSION ON  community acquired pneumonia CLINICAL CASE DISCUSSION ON  community acquired pneumonia
CLINICAL CASE DISCUSSION ON community acquired pneumonia Dr Nikita Ingale
 
Morbidity and Mortality Conference
Morbidity and Mortality ConferenceMorbidity and Mortality Conference
Morbidity and Mortality ConferenceDr.Junaid Nazar
 
a case study on burn injury / case presentation on burn injury
a case study on burn injury / case presentation on burn injury a case study on burn injury / case presentation on burn injury
a case study on burn injury / case presentation on burn injury martinshaji
 
Weekly death round
Weekly death roundWeekly death round
Weekly death roundBeka Aberra
 
Hemodynamic Stress Response of Carbon-Di-Oxide Pneumoperitoneum during Laparo...
Hemodynamic Stress Response of Carbon-Di-Oxide Pneumoperitoneum during Laparo...Hemodynamic Stress Response of Carbon-Di-Oxide Pneumoperitoneum during Laparo...
Hemodynamic Stress Response of Carbon-Di-Oxide Pneumoperitoneum during Laparo...iosrjce
 
Case presentation OP.pptx
Case presentation OP.pptxCase presentation OP.pptx
Case presentation OP.pptxImanuIliyas
 
DVT and PE: A case study
DVT and PE: A case studyDVT and PE: A case study
DVT and PE: A case studyJamie Ranse
 
Mr. Ranganathan
Mr. RanganathanMr. Ranganathan
Mr. RanganathanSujay Iyer
 

Similar to II Pharm. D Bronchopleural Fistula Case (20)

Omar babker
Omar babkerOmar babker
Omar babker
 
Slide materi webinar 28 juni 2020
Slide materi webinar 28 juni 2020Slide materi webinar 28 juni 2020
Slide materi webinar 28 juni 2020
 
Case presentation on multinodular goiter
Case presentation on multinodular goiterCase presentation on multinodular goiter
Case presentation on multinodular goiter
 
Myocardial infraction by satyavardhan pharm.d
Myocardial infraction by satyavardhan pharm.dMyocardial infraction by satyavardhan pharm.d
Myocardial infraction by satyavardhan pharm.d
 
MODIFIED FILE.pptx
MODIFIED FILE.pptxMODIFIED FILE.pptx
MODIFIED FILE.pptx
 
ED John Budd a 72yearold arrived in the emergency depa.pdf
ED  John Budd a 72yearold arrived in the emergency depa.pdfED  John Budd a 72yearold arrived in the emergency depa.pdf
ED John Budd a 72yearold arrived in the emergency depa.pdf
 
ANCA vasculitis and Renal Diseases
ANCA vasculitis and Renal DiseasesANCA vasculitis and Renal Diseases
ANCA vasculitis and Renal Diseases
 
Brain
BrainBrain
Brain
 
LAST SEPT MORTALITY MEET 1.pptx
LAST SEPT MORTALITY MEET 1.pptxLAST SEPT MORTALITY MEET 1.pptx
LAST SEPT MORTALITY MEET 1.pptx
 
MORTALITY AND MORBIDITY.pptx
MORTALITY AND MORBIDITY.pptxMORTALITY AND MORBIDITY.pptx
MORTALITY AND MORBIDITY.pptx
 
ED John Budd a 72yearold arrived in the emergency depa.pdf
ED  John Budd a 72yearold arrived in the emergency depa.pdfED  John Budd a 72yearold arrived in the emergency depa.pdf
ED John Budd a 72yearold arrived in the emergency depa.pdf
 
CLINICAL CASE DISCUSSION ON community acquired pneumonia
CLINICAL CASE DISCUSSION ON  community acquired pneumonia CLINICAL CASE DISCUSSION ON  community acquired pneumonia
CLINICAL CASE DISCUSSION ON community acquired pneumonia
 
Morbidity and Mortality Conference
Morbidity and Mortality ConferenceMorbidity and Mortality Conference
Morbidity and Mortality Conference
 
a case study on burn injury / case presentation on burn injury
a case study on burn injury / case presentation on burn injury a case study on burn injury / case presentation on burn injury
a case study on burn injury / case presentation on burn injury
 
Weekly death round
Weekly death roundWeekly death round
Weekly death round
 
Hemodynamic Stress Response of Carbon-Di-Oxide Pneumoperitoneum during Laparo...
Hemodynamic Stress Response of Carbon-Di-Oxide Pneumoperitoneum during Laparo...Hemodynamic Stress Response of Carbon-Di-Oxide Pneumoperitoneum during Laparo...
Hemodynamic Stress Response of Carbon-Di-Oxide Pneumoperitoneum during Laparo...
 
Case presentation OP.pptx
Case presentation OP.pptxCase presentation OP.pptx
Case presentation OP.pptx
 
DVT and PE: A case study
DVT and PE: A case studyDVT and PE: A case study
DVT and PE: A case study
 
Caso clinico 37 2015 nejm
Caso clinico 37 2015 nejmCaso clinico 37 2015 nejm
Caso clinico 37 2015 nejm
 
Mr. Ranganathan
Mr. RanganathanMr. Ranganathan
Mr. Ranganathan
 

More from Srisharikakumar

Toxic epidermal necrolysis - drug induced (case presentation)
Toxic epidermal necrolysis - drug induced  (case presentation)Toxic epidermal necrolysis - drug induced  (case presentation)
Toxic epidermal necrolysis - drug induced (case presentation)Srisharikakumar
 
Hepatitis A -microbiological presentation
Hepatitis A -microbiological presentationHepatitis A -microbiological presentation
Hepatitis A -microbiological presentationSrisharikakumar
 
Suppositories & pessaries pharmaceutics-1
Suppositories & pessaries pharmaceutics-1Suppositories & pessaries pharmaceutics-1
Suppositories & pessaries pharmaceutics-1Srisharikakumar
 
Syphilis -community pharmacy
Syphilis -community pharmacySyphilis -community pharmacy
Syphilis -community pharmacySrisharikakumar
 
Correlation of pharmacology with case presentation(anticoagulants))
Correlation of pharmacology with case presentation(anticoagulants))Correlation of pharmacology with case presentation(anticoagulants))
Correlation of pharmacology with case presentation(anticoagulants))Srisharikakumar
 
Case study on CABG surgery
Case study on CABG surgeryCase study on CABG surgery
Case study on CABG surgerySrisharikakumar
 

More from Srisharikakumar (7)

Toxic epidermal necrolysis - drug induced (case presentation)
Toxic epidermal necrolysis - drug induced  (case presentation)Toxic epidermal necrolysis - drug induced  (case presentation)
Toxic epidermal necrolysis - drug induced (case presentation)
 
Hepatitis A -microbiological presentation
Hepatitis A -microbiological presentationHepatitis A -microbiological presentation
Hepatitis A -microbiological presentation
 
Suppositories & pessaries pharmaceutics-1
Suppositories & pessaries pharmaceutics-1Suppositories & pessaries pharmaceutics-1
Suppositories & pessaries pharmaceutics-1
 
Syphilis -community pharmacy
Syphilis -community pharmacySyphilis -community pharmacy
Syphilis -community pharmacy
 
Correlation of pharmacology with case presentation(anticoagulants))
Correlation of pharmacology with case presentation(anticoagulants))Correlation of pharmacology with case presentation(anticoagulants))
Correlation of pharmacology with case presentation(anticoagulants))
 
Case study on CABG surgery
Case study on CABG surgeryCase study on CABG surgery
Case study on CABG surgery
 
Sri sha case 1
Sri sha case 1Sri sha case 1
Sri sha case 1
 

Recently uploaded

Aspirin presentation slides by Dr. Rewas Ali
Aspirin presentation slides by Dr. Rewas AliAspirin presentation slides by Dr. Rewas Ali
Aspirin presentation slides by Dr. Rewas AliRewAs ALI
 
(Rocky) Jaipur Call Girl - 9521753030 Escorts Service 50% Off with Cash ON De...
(Rocky) Jaipur Call Girl - 9521753030 Escorts Service 50% Off with Cash ON De...(Rocky) Jaipur Call Girl - 9521753030 Escorts Service 50% Off with Cash ON De...
(Rocky) Jaipur Call Girl - 9521753030 Escorts Service 50% Off with Cash ON De...indiancallgirl4rent
 
CALL ON ➥9907093804 🔝 Call Girls Baramati ( Pune) Girls Service
CALL ON ➥9907093804 🔝 Call Girls Baramati ( Pune)  Girls ServiceCALL ON ➥9907093804 🔝 Call Girls Baramati ( Pune)  Girls Service
CALL ON ➥9907093804 🔝 Call Girls Baramati ( Pune) Girls ServiceMiss joya
 
High Profile Call Girls Coimbatore Saanvi☎️ 8250192130 Independent Escort Se...
High Profile Call Girls Coimbatore Saanvi☎️  8250192130 Independent Escort Se...High Profile Call Girls Coimbatore Saanvi☎️  8250192130 Independent Escort Se...
High Profile Call Girls Coimbatore Saanvi☎️ 8250192130 Independent Escort Se...narwatsonia7
 
Book Paid Powai Call Girls Mumbai 𖠋 9930245274 𖠋Low Budget Full Independent H...
Book Paid Powai Call Girls Mumbai 𖠋 9930245274 𖠋Low Budget Full Independent H...Book Paid Powai Call Girls Mumbai 𖠋 9930245274 𖠋Low Budget Full Independent H...
Book Paid Powai Call Girls Mumbai 𖠋 9930245274 𖠋Low Budget Full Independent H...Call Girls in Nagpur High Profile
 
Vip Call Girls Anna Salai Chennai 👉 8250192130 ❣️💯 Top Class Girls Available
Vip Call Girls Anna Salai Chennai 👉 8250192130 ❣️💯 Top Class Girls AvailableVip Call Girls Anna Salai Chennai 👉 8250192130 ❣️💯 Top Class Girls Available
Vip Call Girls Anna Salai Chennai 👉 8250192130 ❣️💯 Top Class Girls AvailableNehru place Escorts
 
VIP Call Girls Indore Kirti 💚😋 9256729539 🚀 Indore Escorts
VIP Call Girls Indore Kirti 💚😋  9256729539 🚀 Indore EscortsVIP Call Girls Indore Kirti 💚😋  9256729539 🚀 Indore Escorts
VIP Call Girls Indore Kirti 💚😋 9256729539 🚀 Indore Escortsaditipandeya
 
Artifacts in Nuclear Medicine with Identifying and resolving artifacts.
Artifacts in Nuclear Medicine with Identifying and resolving artifacts.Artifacts in Nuclear Medicine with Identifying and resolving artifacts.
Artifacts in Nuclear Medicine with Identifying and resolving artifacts.MiadAlsulami
 
Call Girls Service Surat Samaira ❤️🍑 8250192130 👄 Independent Escort Service ...
Call Girls Service Surat Samaira ❤️🍑 8250192130 👄 Independent Escort Service ...Call Girls Service Surat Samaira ❤️🍑 8250192130 👄 Independent Escort Service ...
Call Girls Service Surat Samaira ❤️🍑 8250192130 👄 Independent Escort Service ...CALL GIRLS
 
Russian Call Girls in Pune Tanvi 9907093804 Short 1500 Night 6000 Best call g...
Russian Call Girls in Pune Tanvi 9907093804 Short 1500 Night 6000 Best call g...Russian Call Girls in Pune Tanvi 9907093804 Short 1500 Night 6000 Best call g...
Russian Call Girls in Pune Tanvi 9907093804 Short 1500 Night 6000 Best call g...Miss joya
 
Low Rate Call Girls Pune Esha 9907093804 Short 1500 Night 6000 Best call girl...
Low Rate Call Girls Pune Esha 9907093804 Short 1500 Night 6000 Best call girl...Low Rate Call Girls Pune Esha 9907093804 Short 1500 Night 6000 Best call girl...
Low Rate Call Girls Pune Esha 9907093804 Short 1500 Night 6000 Best call girl...Miss joya
 
VIP Mumbai Call Girls Hiranandani Gardens Just Call 9920874524 with A/C Room ...
VIP Mumbai Call Girls Hiranandani Gardens Just Call 9920874524 with A/C Room ...VIP Mumbai Call Girls Hiranandani Gardens Just Call 9920874524 with A/C Room ...
VIP Mumbai Call Girls Hiranandani Gardens Just Call 9920874524 with A/C Room ...Garima Khatri
 
Call Girl Coimbatore Prisha☎️ 8250192130 Independent Escort Service Coimbatore
Call Girl Coimbatore Prisha☎️  8250192130 Independent Escort Service CoimbatoreCall Girl Coimbatore Prisha☎️  8250192130 Independent Escort Service Coimbatore
Call Girl Coimbatore Prisha☎️ 8250192130 Independent Escort Service Coimbatorenarwatsonia7
 
Call Girls Colaba Mumbai ❤️ 9920874524 👈 Cash on Delivery
Call Girls Colaba Mumbai ❤️ 9920874524 👈 Cash on DeliveryCall Girls Colaba Mumbai ❤️ 9920874524 👈 Cash on Delivery
Call Girls Colaba Mumbai ❤️ 9920874524 👈 Cash on Deliverynehamumbai
 
Bangalore Call Girl Whatsapp Number 100% Complete Your Sexual Needs
Bangalore Call Girl Whatsapp Number 100% Complete Your Sexual NeedsBangalore Call Girl Whatsapp Number 100% Complete Your Sexual Needs
Bangalore Call Girl Whatsapp Number 100% Complete Your Sexual NeedsGfnyt
 
Call Girls Horamavu WhatsApp Number 7001035870 Meeting With Bangalore Escorts
Call Girls Horamavu WhatsApp Number 7001035870 Meeting With Bangalore EscortsCall Girls Horamavu WhatsApp Number 7001035870 Meeting With Bangalore Escorts
Call Girls Horamavu WhatsApp Number 7001035870 Meeting With Bangalore Escortsvidya singh
 
Call Girls Service In Shyam Nagar Whatsapp 8445551418 Independent Escort Service
Call Girls Service In Shyam Nagar Whatsapp 8445551418 Independent Escort ServiceCall Girls Service In Shyam Nagar Whatsapp 8445551418 Independent Escort Service
Call Girls Service In Shyam Nagar Whatsapp 8445551418 Independent Escort Serviceparulsinha
 
College Call Girls Pune Mira 9907093804 Short 1500 Night 6000 Best call girls...
College Call Girls Pune Mira 9907093804 Short 1500 Night 6000 Best call girls...College Call Girls Pune Mira 9907093804 Short 1500 Night 6000 Best call girls...
College Call Girls Pune Mira 9907093804 Short 1500 Night 6000 Best call girls...Miss joya
 
Low Rate Call Girls Patna Anika 8250192130 Independent Escort Service Patna
Low Rate Call Girls Patna Anika 8250192130 Independent Escort Service PatnaLow Rate Call Girls Patna Anika 8250192130 Independent Escort Service Patna
Low Rate Call Girls Patna Anika 8250192130 Independent Escort Service Patnamakika9823
 

Recently uploaded (20)

Aspirin presentation slides by Dr. Rewas Ali
Aspirin presentation slides by Dr. Rewas AliAspirin presentation slides by Dr. Rewas Ali
Aspirin presentation slides by Dr. Rewas Ali
 
(Rocky) Jaipur Call Girl - 9521753030 Escorts Service 50% Off with Cash ON De...
(Rocky) Jaipur Call Girl - 9521753030 Escorts Service 50% Off with Cash ON De...(Rocky) Jaipur Call Girl - 9521753030 Escorts Service 50% Off with Cash ON De...
(Rocky) Jaipur Call Girl - 9521753030 Escorts Service 50% Off with Cash ON De...
 
CALL ON ➥9907093804 🔝 Call Girls Baramati ( Pune) Girls Service
CALL ON ➥9907093804 🔝 Call Girls Baramati ( Pune)  Girls ServiceCALL ON ➥9907093804 🔝 Call Girls Baramati ( Pune)  Girls Service
CALL ON ➥9907093804 🔝 Call Girls Baramati ( Pune) Girls Service
 
High Profile Call Girls Coimbatore Saanvi☎️ 8250192130 Independent Escort Se...
High Profile Call Girls Coimbatore Saanvi☎️  8250192130 Independent Escort Se...High Profile Call Girls Coimbatore Saanvi☎️  8250192130 Independent Escort Se...
High Profile Call Girls Coimbatore Saanvi☎️ 8250192130 Independent Escort Se...
 
Book Paid Powai Call Girls Mumbai 𖠋 9930245274 𖠋Low Budget Full Independent H...
Book Paid Powai Call Girls Mumbai 𖠋 9930245274 𖠋Low Budget Full Independent H...Book Paid Powai Call Girls Mumbai 𖠋 9930245274 𖠋Low Budget Full Independent H...
Book Paid Powai Call Girls Mumbai 𖠋 9930245274 𖠋Low Budget Full Independent H...
 
Vip Call Girls Anna Salai Chennai 👉 8250192130 ❣️💯 Top Class Girls Available
Vip Call Girls Anna Salai Chennai 👉 8250192130 ❣️💯 Top Class Girls AvailableVip Call Girls Anna Salai Chennai 👉 8250192130 ❣️💯 Top Class Girls Available
Vip Call Girls Anna Salai Chennai 👉 8250192130 ❣️💯 Top Class Girls Available
 
Russian Call Girls in Delhi Tanvi ➡️ 9711199012 💋📞 Independent Escort Service...
Russian Call Girls in Delhi Tanvi ➡️ 9711199012 💋📞 Independent Escort Service...Russian Call Girls in Delhi Tanvi ➡️ 9711199012 💋📞 Independent Escort Service...
Russian Call Girls in Delhi Tanvi ➡️ 9711199012 💋📞 Independent Escort Service...
 
VIP Call Girls Indore Kirti 💚😋 9256729539 🚀 Indore Escorts
VIP Call Girls Indore Kirti 💚😋  9256729539 🚀 Indore EscortsVIP Call Girls Indore Kirti 💚😋  9256729539 🚀 Indore Escorts
VIP Call Girls Indore Kirti 💚😋 9256729539 🚀 Indore Escorts
 
Artifacts in Nuclear Medicine with Identifying and resolving artifacts.
Artifacts in Nuclear Medicine with Identifying and resolving artifacts.Artifacts in Nuclear Medicine with Identifying and resolving artifacts.
Artifacts in Nuclear Medicine with Identifying and resolving artifacts.
 
Call Girls Service Surat Samaira ❤️🍑 8250192130 👄 Independent Escort Service ...
Call Girls Service Surat Samaira ❤️🍑 8250192130 👄 Independent Escort Service ...Call Girls Service Surat Samaira ❤️🍑 8250192130 👄 Independent Escort Service ...
Call Girls Service Surat Samaira ❤️🍑 8250192130 👄 Independent Escort Service ...
 
Russian Call Girls in Pune Tanvi 9907093804 Short 1500 Night 6000 Best call g...
Russian Call Girls in Pune Tanvi 9907093804 Short 1500 Night 6000 Best call g...Russian Call Girls in Pune Tanvi 9907093804 Short 1500 Night 6000 Best call g...
Russian Call Girls in Pune Tanvi 9907093804 Short 1500 Night 6000 Best call g...
 
Low Rate Call Girls Pune Esha 9907093804 Short 1500 Night 6000 Best call girl...
Low Rate Call Girls Pune Esha 9907093804 Short 1500 Night 6000 Best call girl...Low Rate Call Girls Pune Esha 9907093804 Short 1500 Night 6000 Best call girl...
Low Rate Call Girls Pune Esha 9907093804 Short 1500 Night 6000 Best call girl...
 
VIP Mumbai Call Girls Hiranandani Gardens Just Call 9920874524 with A/C Room ...
VIP Mumbai Call Girls Hiranandani Gardens Just Call 9920874524 with A/C Room ...VIP Mumbai Call Girls Hiranandani Gardens Just Call 9920874524 with A/C Room ...
VIP Mumbai Call Girls Hiranandani Gardens Just Call 9920874524 with A/C Room ...
 
Call Girl Coimbatore Prisha☎️ 8250192130 Independent Escort Service Coimbatore
Call Girl Coimbatore Prisha☎️  8250192130 Independent Escort Service CoimbatoreCall Girl Coimbatore Prisha☎️  8250192130 Independent Escort Service Coimbatore
Call Girl Coimbatore Prisha☎️ 8250192130 Independent Escort Service Coimbatore
 
Call Girls Colaba Mumbai ❤️ 9920874524 👈 Cash on Delivery
Call Girls Colaba Mumbai ❤️ 9920874524 👈 Cash on DeliveryCall Girls Colaba Mumbai ❤️ 9920874524 👈 Cash on Delivery
Call Girls Colaba Mumbai ❤️ 9920874524 👈 Cash on Delivery
 
Bangalore Call Girl Whatsapp Number 100% Complete Your Sexual Needs
Bangalore Call Girl Whatsapp Number 100% Complete Your Sexual NeedsBangalore Call Girl Whatsapp Number 100% Complete Your Sexual Needs
Bangalore Call Girl Whatsapp Number 100% Complete Your Sexual Needs
 
Call Girls Horamavu WhatsApp Number 7001035870 Meeting With Bangalore Escorts
Call Girls Horamavu WhatsApp Number 7001035870 Meeting With Bangalore EscortsCall Girls Horamavu WhatsApp Number 7001035870 Meeting With Bangalore Escorts
Call Girls Horamavu WhatsApp Number 7001035870 Meeting With Bangalore Escorts
 
Call Girls Service In Shyam Nagar Whatsapp 8445551418 Independent Escort Service
Call Girls Service In Shyam Nagar Whatsapp 8445551418 Independent Escort ServiceCall Girls Service In Shyam Nagar Whatsapp 8445551418 Independent Escort Service
Call Girls Service In Shyam Nagar Whatsapp 8445551418 Independent Escort Service
 
College Call Girls Pune Mira 9907093804 Short 1500 Night 6000 Best call girls...
College Call Girls Pune Mira 9907093804 Short 1500 Night 6000 Best call girls...College Call Girls Pune Mira 9907093804 Short 1500 Night 6000 Best call girls...
College Call Girls Pune Mira 9907093804 Short 1500 Night 6000 Best call girls...
 
Low Rate Call Girls Patna Anika 8250192130 Independent Escort Service Patna
Low Rate Call Girls Patna Anika 8250192130 Independent Escort Service PatnaLow Rate Call Girls Patna Anika 8250192130 Independent Escort Service Patna
Low Rate Call Girls Patna Anika 8250192130 Independent Escort Service Patna
 

II Pharm. D Bronchopleural Fistula Case

  • 1. II Pharm . D REG NO : 381710525. 2018-2019. 1
  • 2. 2
  • 3. 3
  • 4. A 51 year old man was admitted in our KMCH hospital on 23/7/19 as secondary treatment due to accident in two wheeler on 16/7/19. He was treated in primary set up on 16/7/19 ICD on both sides and ORIF were done @palani .HRCT revealed the hydropneumothorax on the right side of the lung &bronchopleural fistula then numerous bone fractures on the lower limb. Bronchoscopy and thoracoscopic guided glue injection was planned for to prevent the air leak in the lungs on 26/7/19. 4
  • 5.  REG NO: 1547418.  IP NO: F08833.  AGE & SEX: 51 years old male.  MARRITAL STATUS: Married.  DATE OF ADMISSION: 23/7/19 @8:42am.  DATE OF DISCHARGE: 31/7/19 @2:50pm.  PRIMARY CONSULTANTS: Dr. Santha kumar (pulmonologist) & Dr. DMI. Saravana (cardiologist).  RTA : 2wheeler vs 2wheeler on 16/7/19 primarily treated in native place. 5
  • 6.  Present diagnosis: Rt. Hydropneumothorax.  Previous procedure surgery: ICD ORIF Done on 16/7/19.  Provisional diagnosis: COPD & bronchopleural fistula.  Multiple conditions : Rt. Intertrochanteric fracture (ORIF). Rt. Metatarsal fracture. Flial chest.  Procedure’s undergone: (previous) Rt. ICD persistent air leak . Lt. ICD removed. 6
  • 7. 7 ORIF: open reduction internal fixation. Internal plates(internal splints) and screws were placed.
  • 8. 8 Social history: smoker & alcoholic. Past history : No comorbidities. Family history: No comorbidities. Drug allergy : No history of known drug allergy. 1 pack year= 1/2pack/day X 1 yr = 10 cigarettes/1/2pack =10X 365.24packs = 3652.4cigarettes.
  • 9. 9
  • 10. Suggested to perform: ABG ,CBC, ESR, Urea ,Creatinine, Na+, K+, HRCT, RBS, HIV- ELISA, PT/INR, ECHO. ECHO report:  No regional wall motion abnormality. Normal LV systolic function. Trivial mitral regurgitation. Mild and Moderate pulmonary arterial hypertension(RVSP- 50mmHg). Inferior vena cava 1.9cm dilated. No pulmonary embolism/clot. 10
  • 11. 11 contents 23/7/19 24/7/19 25/7/19 26/7/19 27/7/19 28/7/19 29/7/19 30/7/19 Hb 7.8g/dL 7.4g/dL 7.6g/dL 7.6g/dL 7.8g/dL 8.4g/dL 8.6g/dL 8.4g/dL Tc(cells/cumm) 13900cells/cumm. Total RBC ↓2.62million/mm3 DC P L E B M ↑74% ↓21% 02% 00% 03% PCV ↓22.6% MCV 86.4fL MCH 29.9pg/cell. MCHC 34.6g/dL ESR(mm/hr) ↑76mm/hr Platelet 363000cells/µl Urea - creatinine 0.5mg/dL
  • 12. 12 content 23/7/19 Sodium 137mEq/L Potassium 4.8mEq/L HIV Negative Blood group &Rh typing O+ Prothrombin Pt value -16. Control -12 sec. INR -1.43.
  • 13. DATE TIME HR(beats/min) RR(breaths/min) BP (mmHg) %SpO2(with O2) 23/7/19 12:50am 6:00pm 10pm 92(beats/min) 96(beats/min) 98(beats/min) 24 (breaths/min) 22(breaths/min) 26(breaths/min) 100/90(mmHg) 130/80(mmHg) 130/90(mmHg) 100 99 97 24/7/19 6am 10pm 2pm 6pm 10pm 82(beats/min) 102(beats/min) 100(beats/min) 108(beats/min) 112(beats/min) 22(breaths/min) 24(breaths/min) 24(breaths/min) 22(breaths/min) 26(breaths/min) 110/60(mmHg) 100/60(mmHg) 100/80(mmHg) 120/70(mmHg) 120/80(mmHg) 97 96 97 98 98 25/7/19 2am 6am 10am 2pm 6pm 10pm 116(beats/min) 100(beats/min) 114(beats/min) 120(beats/min) 112(beats/min) 100(beats/min) 28(breaths/min) 26(breaths/min) 22(breaths/min) 22(breaths/min) 20(breaths/min) 20(breaths/min) 130/90(mmHg) 130/80(mmHg) 120/70(mmHg) 130/90(mmHg) 130/80(mmHg) 110/60(mmHg) 96 97 98 97 98 99 26/7/19 6am 5pm 6pm 7pm 8pm 9pm 10pm 92(beats/min) 86(beats/min) 88(beats/min) 82(beats/min) 84(beats/min) 86(beats/min) 82(beats/min) 24(breaths/min) 22(breaths/min) 22(breaths/min) 20(breaths/min) 20(breaths/min) 22(breaths/min) 20(breaths/min) 120/80(mmHg) 110/80(mmHg) 120/70(mmHg) 110/60(mmHg) 120/80(mmHg) 110/60(mmHg) 120/80(mmHg) 99 100 100 98 99 98 97 13
  • 14. 14 DATE TIME HR(beats/min) RR(breaths/min) BP(mmHg) %SpO2 27/7/19 6am 10am 2pm 6pm 10pm 100(beats/min) 102(beats/min) 100(beats/min) 104(beats/min) 100(beats/min) 26(breaths/min) 22(breaths/min) 20(breaths/min) 22(breaths/min) 24(breaths/min) 110/60(mmHg) 110/70(mmHg) 100/80(mmHg) 110/70(mmHg) 120/80(mmHg) 97% 92% 91% 91% 97% 28/7/19 6am 10am 2pm 6pm 10pm 98(beats/min) 112(beats/min) 106(beats/min) 100(beats/min) 94(beats/min) 22(breaths/min) 22(breaths/min) 24(breaths/min) 22(breaths/min) 22(breaths/min) 110/60(mmHg) 110/80(mmHg) 120/80(mmHg) 110/70(mmHg) 110/70(mmHg) 98% 96% 96% 97% 97% 29/7/19 6am 10am 2pm 6pm 10pm 116(beats/min) 112(beats/min) 112(beats/min) 110(beats/min) 108(beats/min) 22(breaths/min) 22(breaths/min) 22(breaths/min) 22(breaths/min) 22(breaths/min) 110/70(mmHg) 110/70(mmHg) 110/80(mmHg) 110/70(mmHg) 110/70(mmHg) 100% 96% 96% 97% 98% 30/7/19 6am 10am 2:30pm 6pm 10pm 102(beats/min) 114(beats/min) 116(beats/min) 102(beats/min) 84(beats/min) 22(breaths/min) 24(breaths/min) 26(breaths/min) 24(breaths/min) 20(breaths/min) 130/60(mmHg) 100/70(mmHg) 110/70(mmHg) 120/80(mmHg) 110/70(mmHg) 99% 98% 97% 98% 98%
  • 15. 15 DATE TIME HR(beats/min) RR(breaths/min) BP(mmHg) %SpO2 31/7/19 6am 10am 72(beats/min) 120(beats/min) 20(breaths/min) 22(breaths/min) 110/60(mmHg) 100/70(mmHg) 98% 97%
  • 16. On 23/7/19 @ 8:42am patient admitted in kmch hospital @11:52am patient history was noted as  Tachypnoeic . HR: 94beats/min  ICD Insitu Rt side. RR: 24breaths/min  S1 S2 heard. SpO2: 100%  Pulse rate 90. Temp: 100.5F  BP 140/90mmHg. GRBS: 99mg/dl  Hb-7.8g/dl. Provisional diagnosis: Rt. Bronchopleural fistula. Plan :  Inj. Zosyn 4.5gm IV 8hrly infusion over 30mins. Neb. Levolin 0.63 4hrly respules. Neb. Formonide 0.5mg BD. Incentive spirometry. Tab. P650 BD & Inj. Heparin 5000units S/C OD. 16
  • 17. 17
  • 18. 18 On 23/7/19 @3:20pm Multiple rib fractures  Right 3rd-10th&left 2nd-6th.  Right intertrochanteric fracture.  Right bimalleolar fracture.  Right 4th proximal phalanx Surgery done outside on 16/7/19. Post operative physiotherapy given. ECG: satisfactory cardiac status. @5:00pm Dr. santha kumar patient reviewed : Hb = 7.8g/dL. PLAN: Syp. Dexorange 10ml BD. To do B/L lower limb venous doppler. inj. Clexane 0.4 S/C BD. (heparin was stopped) inj. Tramadol 50mg IV BD. inj. Emeset 4mg IV BD. inj. Paracetamol 1gm IV TID Daily to check Hb.
  • 19. HRCT Scan of lungs:  moderate right hydropneumothorax. Left moderate pleural effusion. Patchy and confluent ground glassing is noted in the bilateral lung fields. Fractures as detailed. Doppler study of left lower limb veins: No evidence of deep venous thrombosis. 19
  • 20. 20  The patient was diagnosed with hydropneumothorax by the HRCT scan evidence report.  The patients ESR was found to be moderately high 76mm/Hr.  The patients Total RBC count was extremely low to 2.62million/µL (hemolysis).  It can be due to accident blood loss and blood vessel injury and bone marrow damage can also leads to this deadly conditions.  https://www.medicalnewstoday.com
  • 21. 21 Hydropneumothorax is treated by ICD and bronchoscopy with glue injection .
  • 22. 22 On 23/7/19 @12: 50pm  Temp: 98.6F  Pulse: 92/min  RR : 24/min  SpO2: 100%  BP: 140/90mmHg.  Pain persists Total intake = 750ml Total output= 2300ml  On 24/7/19 @ 8:55am patient reviewed Plan on 23/7/19:  Traumatic B/L pneumothorax . Inj. Para 1gram IV  Right bronchopleural fluid ,flial chest. Inj. Augmentin 1.2 gram IV  Right hydropneumothorax. Inj. Pan 40mg IV BP dropped to 110/60. Inj. Emeset 4gram IV HR dropped to 82beats/min. RR dropped to 22breaths/min. Total intake = 850ml %SpO2 is 97% & Temp 98.8F. Total output = 1900ml Complaint of difficulty in breathing. Cough with expectoration.
  • 23. On 25th @ 8:45am  Temp: 99bts/min  HR: 100bts/min  RR: 26breaths/min BP: 130/80mmHg. %SpO2: 97% with 5 litres of oxygen. Complaints of : cough with expectoration & difficulty in breathing. PLAN: D3  Inj. Zosyn Inj. Clexane Neb. Levolin Neb. Formonide Syp. Dexorange. Inj. Tramadol. Plan for bronchoscopy tomorrow@ 9: 30 incentive spirometry @4:45pm inj. Ketorolac 3mg IV in 100ml NS (BD). 23
  • 24.  Under general anaesthesia bronchoscopy and thoracoscopic for BPF was done. 0.5ml of glue in each segment is injected. NPO till 4pm. & monitoring vitals every 15mins till 4pm. To send drain fluid for Antibiotic susceptibility test for bacterial presence of culture detection. D4 inj. Zosyn Neb. Levolin continue till 4pm. Total intake = 900ml Drain=100ml Urine=2500ml Total output = 2600ml. On 27/7/19 @9:50 am Patient is feeling better Air leak has been decreased. Mobilise out of bed ,incentive spirometry ,Stop ketorolac ,restart inj.clexane & high protein diet. 24
  • 25. 25 On 29/7/19 @ 8:45am complaint of pain at the site of ICD Not passed stools since 6 days. Rt. ICD =30ml. No air leak. On 30/7/19 @ 12:30pm ICD removed with strict aseptic condition. PLAN: Tab. Chymoral forte (TID) Tab. Myoril 8mg (BD) On 31/7/19 @8:10am Minimal pain @ICD site & patient mobilized. stat dulcoflex 2dose @12pm rectal route.
  • 26. 26
  • 27.  To reduce the pain .  To reduce the risk and comorbidities.  To improve the breathing trouble .  To increase the red blood cell count.  To prevent from infection.  To make the patient mobilise cost effectively. 27
  • 28. 28
  • 29. 29 DRUG DOSE ROUTE & FREQUENCY TIME START DATE END DATE Inj. Zosyn 4.5gm IV & TID 2am 10am 6pm 23/7 31/7@6am Neb. Formonide 0.5mg Inhalation & BD 6am 6pm 23/7 31/7@6am Tab. P.650 650mg Oral & BD 9am 9pm 23/7@2pm 23/7dose &Route Changed Inj. Para 1gm IV & TID 6am 2pm 10pm 23/7 31/7@6am Inj. Heparin 5000units IV & OD 10am 23/7 23/7 Inj. Clexane 0.4mg S/C & BD 11am 11pm 23/7 24/7 Changed as OD Inj. Clexane 0.4mg S/C & OD 11am 24/7 31/7@11am DRUG CHART:
  • 30. 30 DRUG DOSE ROUTE & FREQUENCY TIME START DATE END DATE Neb. Levolin 0.63mg Inhalation & Q4H 2am 6am 10am 2pm 6pm 10pm 23/7 31/7@10am Prosure protein powder 2tsp Oral & OD 6am 23/7@7pm 27/7 frequency changed to BD Syp. Dexorange 10ml Oral & BD 9am 9pm 23/7 31/7@9am Inj. Emeset 4mg IV & BD 6am 6pm 23/7 31/7@6am Inj. Tramadol 50mg IV & BD 6am 6pm 23/7 31/7@6am Inj. Ketoral 30mg IV & BD 8am 8pm 25/7 27/7@8am Tab. Chymoral forted’s - Oral & TID 9am 2pm 10pm 30/7 31/7@9am
  • 31. 31 C:UsersSRI SHARIKA KUMARDownloadsInhaled corticosteroids plus long- acting beta2-agonists as a combined therapy in asthma. - PubMed - NCBI.mhtml PHARMACIST RECOMMENDATION: https://www.ncbi.nlm.nih.gov/m/pubmed/27877033/
  • 32.  There is no serious drug- drug , drug-food, drug-disease interaction.  MILD AND FAIR RELIABILITY:  Ondansetron will decrease the absorption of tramadol.  Ondansetron will decrease the absorption of acetaminophen.  Enaxoparin and Toradol administration cause enhanced effect of anticoagulant property of enaxoparin. PHARMACIST RECOMMENDATION: Tramadol is an centrally acting analgesic also triggers the chemoreceptor trigger zone so that patient have a chance to vomit , so to avoid that aceclofenac and paracetamol combination or diclofenac combination can be used. Antiemetics can be omitted from the treatment chart. http://apm.amegroups.com/article/view/1038/1264 32
  • 33.  What to avoid ? Don’t s  smoking should be strictly avoided. Not to lift more than 3.5kgs until the fractured bones get heal. No heavy physical activity.  Does: Take all the prescribed medications without fail. Take good rest. Use the spacer and inhaler as instructed . Gargle after use of spacers.  DRUG DETAILS: Tab. Pan 40mg- should be taken before food. 2hours gap should be given while taking Tab. Pan & Tab. Cefakind CV 625mg. Gap of 2mins should be given between the puffs of spacer. 33
  • 34. stable discharge on 31/7/19@2:50pm (spirometry to continue) 34 Medications Dosage Morning Afternoon Evening Night A/B Food Duration Tab. Ultracet 37.5mg/325mg 1 0 0 1 AF 1 week MDI Formonide via spacer 200 2puffs 0 0 2puffs 1 week Prosure protein powder 2scoops in Water Once a day 1 week Tab. Cefakind CV 625mg 1 1 0 1 AF 1 week Tab. Pan 40mg 1 0 0 0 BF 1 week MDI Levolin 0.5mcg 2puffs 2puffs 0 2puffs 1 week Syp. Dexorange 10ml 0 0 10ml 1 week
  • 35. 35  Before the second puff Give 2mins gap.  Atlast gargling is necessary to avoid fungal mouth infections.