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Nutrition and Nutrient Review, and Planning
Guide – Plant-based or Vegan Diets
The 8th annual national Plant-based Prevention of Disease (PPOD)
Conference, June 25, 2021
North Carolina State University, Raleigh, NC
 Tim Radak, RDN, DrPH, MPH
Academic Coordinator - PhD Public
Health Program, Core Faculty
College of Health Professions
Walden University
timothy.radak@mail.waldenu.edu
Background
Current: PhD in Public Health Academic Coordinator/Faculty
College of Health Professions, Walden University
Previous:
Assistant Professor of Nutrition and Dietetic Internship Director
College of Health Sciences, Appalachian State University
Senior Research Program Manager
Cancer Prevention Institute of California, Fremont, CA
Director of Nutrition
Physician's Committee for Responsible Medicine, Washington DC
Loma Linda University – M.P.H.,Dr.PH, RDN -Leader in investigating relationship between
vegetarian diet and health and disease outcomes. Post-doc at U of C Davis/WHNRC.
Credentialed as a Registered Dietitian Nutritionist for 21 years.
John McDougall M.D. Program - Interned
Studying, doing research, and publishing in the fields of Nutrition and Chronic Disease for
over 20 years with a particular focus on plant foods for minimizing disease and
optimizing health. Published in 2013 the first ever entire chapter in academic text on
plant based diets for food and ecology text.
Nutrition and Nutrient Review, and Planning Guide
⁕Plant-based or Vegan Diets⁕
 1) Describe and understand the nutritional and nutrient
benefits of a well-planned vegan diet. Why is this diet
optimal for health and disease prevention AND the best
health-care solution?
 2) Describe and understand nutrition and nutrients of
potential concern in Omnivore diets in order to attain
optimal nutrition status and disease prevention in Plant-
based Vegan Diets
 3) Discuss available vegan health promotion
research and support materials.
 Disclosures--
Nothing to disclose
First – a moment of recognition
First, why a vegan or plant-based diet? A Healthcare
Solution – Plant-based Diets
Plant Based Diets - Vegetarian/Vegan Diets – Tend to result in:
 lower BMI (Crowe, 2013), less caloric intake (Farmer, 2011)
 less risk for obesity or overweight (Berkow, 2006, Fraser, 2009)
 less incidence or risk of type 2 diabetes (Tonstad, 2011, 2013; Jardine, 2021)
 Less risk for dementia, better mood scores, less depression (Giem, 1993;
Beezhold, 2010; Beezhold, 2014; Link, 2008; Shen, 2021)
 less CHD/IHD (Fraser, 1999, 2009), CVD and CVD/IHD mortality (Key, 1999, Fraser, 2009;
Glenn, 2019) . Vegans (males) showed better protection for all-cause mortality,
IHD, and CVD (Le, 2014).
 less all cause mortality (Orlich, 2013)
 less all cause mortality in chronic kidney disease (CKD) patients (Chauveau,
2019)
 less cerebrovascular disease or stroke (Kwok, 2014; Kappagoda, 2006; Chiu 2020)
 lower incidence of high blood pressure (Crowe, 2013)
 lower pro-inflammatory markers and immune biomarkers, C-reactive
protein (Craddock, 2019; Yu. 2014; Franco-de-Moraes, 2017; Shah, 2018; Fontana, 2007; Haghighatdoost, 2015;
Paalani, 2011; Eichelmann, 2016; Menzel, 2020)
First, why a vegan or plant-based diet? A Healthcare
Solution – Plant-based Diets
Cont’d - Plant Based Diets - Vegetarian/Vegan Diets – Tend to result in:
 some of the highest disease fighting biomarkers, increase in
phytochemicals/antioxidants (Craig, 2009; Miles, 2019)
 increased fiber intake (Rizzo, 2013), less diverticulitis (Crowe, 2011),
 more nutrient density (Farmer, 2011)
 lower pathogenic dietary factors: saturated fat, cholesterol, LDL-C (Dewell,
2008; Craig, 2010)
 less production of TMAO (trimethylamine N-oxide), and HO-1 (heme-oxygenase-
1), both atherosclerotic risk factors (Chiu, 2020; Xu, 2010; Cinegaglia, 2020)
 similar bone health to omnivores with adequate calcium (Mangel, 2014)
[Dr. Laura Pridemore - Pediatric Evidence of Dietary Effects on Growth Rates, Bone Health and Common Illnesses]
 less gallstones/disease (Pixley, 1985; Chang, 2019)
 less incidence of gout (Chiu, 2020)
 less pollutants in vegan diet (organochlorine
concentrations) (Arguin, 2010)
First, why a vegan or plant-based diet? A Healthcare
Solution – Plant-based Diets
Cont’d - Plant Based Diets - Vegetarian/Vegan Diets – Tend to result in:
 some of the highest gut equol production (a soy isoflavone metabolite)
(Barnard, 2021; Wu, 2016; Setchell, 2006)
 less long term hospitalization/medical costs/medication usage (Crowe, 2013;
Knutsen,1994; Lin, 2019; Dos Santos, 2021)
 increase in longevity (Le, 2014)
First, why a vegan or plant-based diet? A Healthcare
Solution– Plant-based Diets
Plant-Based Diets (Vegan or Vegetarian Diets) - Therapeutic
Significant volume of research suggests favorable or positive effects from
plant based diets on most chronic diseases or disease risk factors:
 CHD/CAD (Koertge, 2003, Esselstyn, 2014)
 Hypertension (Berkow, 2005; Lindahl, 1984)
 Diabetes (Trapp, 2010; McMacken, 2017; Kelly, 2020)
 Diabetic neuropathy (Crane,1994)
 Renal Disease/chronic kidney disease (CKD) (Cases,2019; Joshi, 2020)
 Obesity (Gardener, 2005, McDougall, 2014)
 Metabolic syndrome (Turner-McGrievy, 2014; Marrone, 2021)
 Some cancers (Fraser, 2009, Lanou, 2010)
 Menopausal Symptoms (Barnard, 2021)
First, why a vegan or plant-based diet? A Healthcare
Solution– Plant-based Diets
Plant-Based Diets (Vegan or Vegetarian Diets) - Therapeutic
Significant volume of research suggests favorable or positive effects from
plant based diets on most chronic diseases or disease risk factors:
 Depression and quality of life (Agarwal, 2014)
 Osteoarthritis (Clinton, 2015)
 Migraine (Bunner, 2014)
 Rheumatoid Arthritis (Alwarith, 2019; Hänninen, 1999; Kjeldsen-Kragh, 1999; McDougall, 2002)
 Reducing inflammatory markers (Menzel, 2020; Sutliffe, 2015; Shawh, 2018; Elkan, 2008;
Eichelmann, 2016; Jaceldo-Siegl, 2018)
 [Dr. Andrew Freeman - Plant-based Diets in 2021: The Data Keep Pouring In]
 [Dr. Brie Turner-McGrievy- Past, Present, and Future: Two Decades of Plant-
based Diet Research]
First, why a vegan or plant-based diet? A Healthcare
Solution– Plant-based Diets
Plant-Based Diets (Vegan or Vegetarian Diets) - Therapeutic
A bit more about reducing inflammatory markers because…
 Inflammation linked to diabetes, metabolic syndrome, cardiovascular
disease, cancer, rheumatoid arthritis, inflammatory bowel disease,
asthma, autoimmune and neurodegenerative disordersand chronic
obstructive lung disease (Furman, 2019).
 How Beneficial? One example.
 Fiber rich plant based diets in gut convert fiber to SCFA which are anti-
inflammatory.
 And, specialized colonic microbes also break down plant cell walls and
release “phytochemicals” such as the polyphenols, anthocyanins,
phenolics, and flavins, all of which also have anti-inflammatory,
antioxidant, and antineoplastic properties (O'Keefe, 2019).
Why a vegan or plant-based diet?
 Other non-nutritional reasons too
 Baroni, 2007 “vegetarian and vegan diets could play an important role in preserving environmental resources
and in reducing hunger and malnutrition in poorer nations”.
 [Sherene Chou, MS RDN: “Rethinking Sustainability through Food and
Social Justice” ]
First, why a vegan or plant-based diet? A Healthcare Crisis
Solution
 How much does an unhealthy lifestyle (including poor diet) cost us?
 Heart Disease: $317 billion
 Obesity: $147 billion
 Diabetes: $245 billion
 Hypertension: $46 billion
 Stroke: $34 billion
 Cancer care $157 billion
First, why a vegan or plant-based diet? A Healthcare Crisis
Solution
 How much does an unhealthy lifestyle (including poor diet) cost us?
 Three-quarters of health care spending
goes to treat preventable chronic illnesses
(Bodai, 2018; Schmidt, 2016; Chapel, 2017).
 85% of the nation’s $3.5 trillion annual
health care expenditures are for people
with chronic and mental health
conditions(Fleischhacker, 2021).
 80% of chronic conditions could be avoided
through the adoption of healthy lifestyle recommendations (Bodai, 2018).
 Recent Kaiser Family Foundation research survey of employers predicts
healthcare costs will become unsustainable within the next 5-10 years
highlighting a broken healthcare system (Waddill, 2021).
First, why a vegan or plant-based diet? A Healthcare Crisis
Solution
 How much does an unhealthy lifestyle (including poor diet) cost us?
 Diet is now the #1 risk factor in the US for mortality and morbidity
 US Burden of Disease Collaborators, The State of US Health, 1990-2016: Burden of Diseases, Injuries, and Risk Factors Among US States. JAMA. 2018 Apr
10;319(14):1444-1472.
What constitutes a well-planned vegan/plant-based diet
 Variety of minimally processed/whole food, nutrient dense fruits,
vegetables, beans and legumes, grains, nuts and seeds (minimal
processed food)
 Variety and diversity in each of the above categories will help ensure
adequate protein, calcium, iron, zinc, selenium, and other vitamins,
minerals, macronutrients.
 Reliable source of
Vitamin B-12 (preferably Cyanocobalamin – more stable,
better efficacy, and better for oral supplementation than
Methylcobalamin types, and caution if supplement
via multi-vitamin that includes B-12) (Rizzo, 2016)
 Source of Iodine – grains and some vegetables and fruits but is
dependent on soil composition. Best option is occasional
seaweeds “sea vegetables” (don’t overdo it) which
absorb iodine from seawater. Avoid iodized salt
due to health effects of sodium. (bonus: EPA, Zinc)
What constitutes a well-planned vegan/plant-based diet
 Variety of minimally processed/whole food, nutrient dense fruits,
vegetables, beans and legumes, grains, nuts and seeds (minimal
processed foods)
 Source of Vitamin D – main source dependent
on sunlight exposure, latitude, age, skin
type and degree of exposure i.e. clothes, work in office.
 Essential Fatty Acids – moderate Omega 6 intake (easy when limiting
refined vegetable oils and processed products containing them), not for
inflammation reasons but to reduce effect on Omega 3 incorporation
Omega 3 (α-Linolenic acid) – Sample meal without
walnuts, chia, flax or algae, or significant oil or fortified
foods
 Breakfast
Oatmeal – 1 ½ cups cooked .063g
½ cup red raspberries .0775g
1 slice wheat bread .045g
margarine – none
1 cup soymilk .19g
 Lunch
Salad –
Spinach 2 cups raw .082g
Broccoli 1 cup raw .057g
Cauliflower ½ cup cooked .104g
Tomato 1 cup chopped .005g
½ cup pumpkin seeds .033g
Avocado pureed ½ c .128g
Italian salad dressing 1 Tbsp .211g
Vegetarian baked beans 1 cup .13g
 Dinner
1 cup cooked Kale .438g
1 cup cooked kidney beans .375g
1 cup cooked brown rice .022g
1 1/2 cup cooked yam .018
1 oz pretzels .08g
1 cup blueberries .086g
 Snack
1 cup cherries .036
 Adequate Intakes
Males 1.6g/day
Females 1.1g/day
 Total for sample meal 2.19g
What constitutes a well-planned vegan/plant-based diet
 How important is variety?
 Ex. Intestinal immune cells have specific receptors and proteins for
individual phytochemicals found in various F and V that enhance and
sustain intestinal immune function within the gut and specific F and V act
to reduce risk of colon cancer in separate and specific areas of the colon
(Veldhoen , 2012; Annema, 2011; Murakami 2012).
See: https://nutritionfacts.org/video/the-broccoli-receptor-our-first-line-of-defense-
2/
 [Dr. Leah Frame- Nutrition and the Gut Microbiome]
A well-planned vegan/plant-based diet
What constitutes a poorly-planned vegan/plant-based
diet?
 Not following the previous slide recommendations closely enough…
 Example: B12 deficiency meta-analysis (Veg/Vegans) 0% - 86.5%
adults/elderly, 45% in infants, 0% - 33.3% in children/adolescents, and
from 17% -39% among pregnant women (Pawlak, 2014)
 “Junk food vegan” Dunk’in Donut to vegan donut, beef
burrito to cheese burrito, Breyers ice cream to vegan
Breyers, standard cookie to Oreo, etc.
Could addictive nature and convenience of
SAD foods lend to increased intake as a vegan?
 Over reliance on meat analogues – use as transitional/treat
 Processed and “fast” food (Sodium ↑ CVD) (Wang, 2020)
 Switching from butter to plant-based substitutes (coconut oil)
may actually be worse in terms of saturated fat
(ex 1 Tsp 12 g sat fat or 58% daily value)
What constitutes a poorly-planned vegan/plant-based
diet
 Research on vegan diets – Are we underestimating the power of plant-
based vegan diets from available research studies?
How much more improvement in findings and outcomes if participants
were truly following a whole foods, minimally processed diet???
Possible reasons for a poorly-planned vegan/plant-
based diet
 Not following meeting a patient where ‘they are’
 To understand this it is first helpful to give attention to
1. the diet previous to making the switch to a plant based diet
2. attention to the psychological stage or readiness to make a significant
change such as diet.
 “The present state of prevailing dietary practices, plant based or otherwise, in the
United States and increasing swathes of the world, may be summed up in one
word: calamitous. The modern, animal-food-centric, highly processed diet is
devastating to planetary and public health alike” (Katz, 2019 -Plant-Based Diets for Reversing
Disease and Saving the Planet: Past, Present, and Future)
ForwardFood, CBORD, Powering Up with Plant-Strong Programs. ForwardFood.org
Possible reasons for a poorly-planned vegan/plant-
based diet
 Not following meeting a patient where ‘they are’
 To understand this it is first helpful to give attention to
1. the diet previous to making the switch to a plant based diet
Possible reasons for a poorly-planned vegan/plant-
based diet
 Not following meeting a patient where ‘they are’
 To understand this it is first helpful to give attention to
1. the diet previous to making the switch to a plant based diet
 Processed foods (consumption of processed, convenience foods, with a
long shelf-life) – dominate the US diet
 A national US study found ultra-processed
foods (processed foods “engineered” to be
high in fat/oils, salt, sugar) made up over
half of daily calories and contributed a
staggering 89.7% of the energy intake from
added sugars (>10% total energy from added sugars)
(Martínez Steele, 2016)
Possible reasons for a poorly-planned vegan/plant-
based diet
 Not following meeting a patient where ‘they are’
 Sodium, fat, dairy/cheese (casomorphine - opioid peptides), refined
carbohydrate (Addictive)
– Foods with highest addictive-like qualities: pizza, French fries and
cheeseburgers, ice-cream, cookies, potato chips, chocolate (Schulte, 2015)
 Added oils (oil is a processed food)
 Poor sources/intake of Vitamin B12, D, Zinc, Selenium,
Iron, Iodine, Calcium, over reliance on Omega 6
 Non diverse dietary intake (that may rely on taking supplements to meet
nutrition needs)
 Minimal and low diversity: fruit and vegetable, whole grains, legumes
 Said another way: maintaining a western style diet
minus animal products
Possible reasons for a poorly-planned
vegan/plant-based diet
 Not following meeting a patient where
‘they are’
 Despite much nutrition info, most are
confused about nutrition, MD/RD’s
contradict each other; marketing:
main driver of education??
 The most important problem is our
poor lifestyle choices based on
misinformation (Bodai, 2018).
 Marketing a known unhealthy product in
dietitian magazine and with a slight towards
vegetarians…
 “Deli meats are pre cooked convenient
sources of protein…in fact the Iron and
Zinc are more bioavailable than vegetarian
sources!
 “processed simply means prepared”
Fruit and Vegetable intake in USA
 Year 2015 - Approximately 12% of US adults
consumed the recommended number of
servings for fruits (was 13.1% in 2013) (CDC, 2017).
 In 2015, more than 37% of adolescents and
40% of adults said they ate fruit less than once
a day (CDC, 2017).
 2015 - Approximately 9% of US adults consume the recommended
number of servings for vegetables (was 8.9% in 2013) (CDC, 2017).
 2015, 39% of adolescents and 22% of adults said they ate vegetables
less than once a day (CDC, 2017).
 91% did not meet vegetable
intake recommendations!
Vegetable intake in USA
 Quality and Quantity are both important…
 Half of the vegetable intake (51%) comes from potatoes or tomatoes,
most of which is in the form of fried potatoes or chips or pizza or pasta
sauce (Guthrie, 2014).
Fruit and Vegetable intake in USA – lacking diversity
USDA Economic Research Service –Ag and Food Statistics, April 2017
https://www.ers.usda.gov/webdocs/publications/83344/ap-075.pdf?v=42853
Possible reasons for a poorly-planned vegan/plant-
based diet
 Psychological readiness or willingness to change also affects quality of
vegan/plant-based diets/habits.
 No amount of pamphlets, facts,
and discussion are effective
unless we are meeting a patient
where they are psychologically.
Prochaska, J.O., DiClemente, C.C., & Norcross, J.C. (1992). In search of how people change: Applications to the addictive behaviors. American
Psychologist, 47, 1102-1114. PMID: 1329589.
[Round Table: What Blocks the Benefits of Plant-based Whole Foods? Not
Affordable? Poor Access? Seen as Bland/Boring? Chair: Renae Thomas, MD,
Lily Correa, MPH RDN DipACLM, Dawn Hilton-Williams, BA]
Possible reasons for a poorly-planned vegan/plant-
based diet
 Impact of COVID-19. During pandemic 40% of Americans struggled with
mental health in some form (Czeisler, 2020).
 Will the US be similar to Poland when data arrives?
 Dietary Choices and Habits during COVID-19 Lockdown: Experience
from Poland - Aleksandra Sidor , Piotr Rzymski
 Over 43.0% and nearly 52% reported eating and snacking more,
respectively, and these tendencies were more frequent in overweight and
obese individuals. Almost 30% and over 18% experienced weight gain
(mean ± SD 3.0 ± 1.6 kg) and loss (-2.9 ± 1.5 kg), respectively. Overweight,
obese, and older subjects (aged 36-45 and >45) tended to gain weight more
frequently, whereas those with underweight tended to lose it further.
Increased BMI was associated with less frequent consumption of
vegetables, fruit, and legumes during quarantine, and higher intake of meat,
dairy, and fast-foods. An increase in alcohol consumption was seen in
14.6%, with a higher tendency to drink more found among alcohol addicts
 Recent Investigations of Public Health Nutrition and COVID-19 in Developed
Countries – Caroline Um – June 2021 American Society for Nutrition -
decrease in healthy foods, vegetables whole grains in US
Possible reasons for a poorly-planned vegan/plant-
based diet
 Impact of COVID-19. Some positive news
Those following a plant-based diet had 73 percent lower odds of experiencing a
'moderate-to-severe' course of COVID-19 compared to meat-eaters
 Actor Bronson Pinchot
During quarantine – removed all junk food
from refrigerator and pantry and replaced
with healthy vegan food, minimal exercise: 60#.
Struggled with weight fluctuating since age 6
and for first time is stable from following
vegan diet.
Figure
Other considerations when recommending plant-based
diets
Radnitz C, Beezhold B, DiMatteo J. Investigation of lifestyle choices of individuals following a vegan diet for health
and ethical reasons. Appetite. 2015 Jul;90:31-6. doi: 10.1016/j.appet.2015.02.026. Epub 2015 Feb 25.
•Meeting a patient where they “are”
•Recent international online survey, Fruit and Vegetable Intake For from
US. 245 vegans (45 for health reasons (HEA), 201 for ethical reasons
(ETH))
•Very good intakes overall. Fruit intake significantly greater in those who
choose to follow vegan diet for health reasons
Dietary Guidelines and Diagrams
 Adapt existing and possibly familiar guidelines/diagrams - A Plant Based Diet
more closely resembles what the current dietary recommendations are for
intakes of fruits, vegetables, whole grains, beans/legumes, intake of
saturated fats, than any other diet (Farmer, 2011).
 Add: healthy seasonings i.e. herbs/spices/nutritional yeast, Braggs or coconut
aminos, balsamic vinegar
 Dr. McDougall sauces/dressings: https://www.drmcdougall.com/health/education/recipes/mcdougall-recipes/?cat-
id=9&cat-name=Dressings+%26+Sauces
 Starting with the Dietary Guidelines for Americans 2015–2020: Healthy
Vegetarian Eating Pattern “This Pattern can be vegan if all dairy choices are
comprised of fortified soy beverages (soymilk) or other plant-based dairy
substitutes.” p.86
Plant based Resources
 Modified Food Guide Pyramid for Lactovegetarians and Vegans - Colleen A. Venti and
Carol S. Johnston http://jn.nutrition.org/content/132/5/1050.full.pdf+html
 Vegetarian Food Guide Pyramid – Loma Linda University http://www.vegetariannutrition.org/6icvn/food-
pyramid.pdf
 Vegetarian Food Guide Pyramid – Oldways Preservation Trust https://oldwayspt.org/traditional-
diets/vegetarian-vegan-diet
 Academy of Nutrition and Dietetics – Position Paper on Vegetarian Diets
https://www.eatrightpro.org/-/media/eatrightpro-files/practice/position-and-practice-papers/position-papers/vegetarian-diet.pdf
 USDA Food and Nutrition Center – Vegetarian Nutrition https://www.nal.usda.gov/fnic/vegetarian-
nutrition
 PCRM - Nutrition Guide for Clinicians https://nutritionguide.pcrm.org/nutritionguide
 Tuso, PJ, et al. Nutritional Update for Physicians: Plant-Based Diets. Perm J. 2013 Spring;
17(2): 61–66
 Hever J. Plant-Based Diets: A Physician’s Guide. Perm J. 2016 Summer; 20(3): 15-082.
 Bodai, et al. Lifestyle Medicine: A Brief Review of Its Dramatic Impact on Health and
Survival. Perm J. 2018;22:17-025
 Counseling Vegan Clients – Matt Ruscigno, MPH, RD - Today's Dietitian
https://www.todaysdietitian.com/newarchives/1017p20.shtml
 The Plantrician Project -PlantPure Rx – 10 day food-supported
immersion program that introduces patients to the health benefits of a
whole food, plant-based diet. https://www.plantpurenation.com/pages/plantpure-rx
Plant based Resources
 Excellent free Print Resources for patients from American College of Lifestyle Medicine
https://www.lifestylemedicine.org/ACLM/Tools_and_Resources/Print_Resources.aspx
In the right direction
 Major organizations have endorsed/supported plant-based diets
– American Institute For Cancer Research
– Academy Of Nutrition And Dietetics
– American Heart Association
– American College of Cardiology/AHA - clinical practice
guidelines - Primary prevention of CVD
– American Diabetes Association
– Kaiser Permanente
– Aramark - serves nearly 2 billion meals/yr - launched a major plant-forward initiative
 The American Medical Association’s House of
Delegates has adopted a resolution calling on
hospitals to provide plant-based meals and
remove processed meats from menus. And the
AMA has also written a letter last year to the
USDA to indicate in the dietary guidelines that
meat and dairy are optional.
 In Lebanon, a hospital a few months ago
become the first to use a 100% entirely vegan menu
In the right direction
 Nielsen reports (prior to COVID-19) that more than 39 percent of consumers in
the US are trying to incorporate more plant-based foods into their diet.
 Interest continues to ↑ (environment,
health, ethics, animal welfare). Sales of
plant-based foods ↑ 27% in 2020
[Lily Correa - Guiding Patients’ Long-term Success, One Plate at a Time]
[Jasmol Sardana - “Creating Lasting Behavior Change: How to Speak with Our Patients
about Diet and Lifestyle”]
In the right direction
• This article provides insights to
aspects of diet and chronic
illness and discusses how the
plant-based movement could
redefine current understanding
of chronic disease. The ethical
justifications for recommending
of a plant-based diet are
analyzed.
• The article concludes that not
advocating for plant-based
nutrition is unethical and
harms the planet and patients
alike.
Storz MA. Will the plant-based movement redefine
physicians' understanding of chronic disease? New Bioeth.
2020 Jun;26(2):141-157.
Nutrition and Nutrient Review, and Planning
Guide – Plant-based or Vegan Diets
The 8th annual national Plant-based Prevention of Disease (PPOD)
Conference, June 25, 2021
North Carolina State University, Raleigh, NC
 Tim Radak, RDN, DrPH, MPH
Academic Coordinator - PhD Public
Health Program, Core Faculty
College of Health Professions
Walden University
timothy.radak@mail.waldenu.edu
References – N = 101
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Multiethnic Adult Population in the Corporate Setting Reduces Depression and Anxiety and Improves
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 Alwarith J, Kahleova H, Rembert E, Yonas W, Dort S, Calcagno M, Burgess N, Crosby L, Barnard ND.
Nutrition Interventions in Rheumatoid Arthritis: The Potential Use of Plant-Based Diets. A Review. Front
Nutr. 2019 Sep 10;6:141.
 Annema N, Heyworth JS, McNaughton SA, Iacopetta B, Fritschi L. Fruit and vegetable consumption and
the risk of proximal colon, distal colon, and rectal cancers in a case-control study in Western Australia. J
Am Diet Assoc. 2011 Oct;111(10):1479-90.
 Arguin H, Sánchez M, Bray GA, Lovejoy JC, Peters JC, Jandacek RJ, Chaput JP, Tremblay A. Impact of
adopting a vegan diet or an olestra supplementation on plasma organochlorine concentrations: results
from two pilot studies. Br J Nutr. 2010 May;103(10):1433-41.
 Barnard ND, Kahleova H, Holtz DN, Del Aguila F, Neola M, Crosby LM, Holubkov R. The Women's
Study for the Alleviation of Vasomotor Symptoms (WAVS): a randomized, controlled trial of a plant-
based diet and whole soybeans for postmenopausal women. Menopause. 2021 Jul 12.
 Baroni L, Cenci L, Tettamanti M, Berati M. Evaluating the environmental impact of various dietary
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 Beezhold BL, Johnston CS, Daigle DR. Vegetarian diets are associated with healthy mood states: a
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9-26.
 Beezhold B, Radnitz C, Rinne A, DiMatteo J. Vegans report less stress and anxiety than omnivores.
Nutr Neurosci. 2014 Nov 21.
 Berkow SE, Barnard ND. Blood pressure regulation and vegetarian diets. Nutr Rev. 2005 Jan;63(1):1-8.
 Berkow SE, Barnard N. Vegetarian diets and weight status. Nutr Rev. 2006 Apr;64(4):175-88.
 Bodai B et al. Lifestyle Medicine: A Brief Review of Its Dramatic Impact on Health and Survival. Perm J
2018;22:17-025.
References
 Cases A, Cigarrán-Guldrís S, Mas S, Gonzalez-Parra E. Vegetable-Based Diets for Chronic Kidney
Disease? It Is Time to Reconsider. Nutrients. 2019 Jun 4;11(6):1263.
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June 2021 radak vegan nutrition primer 7 1-21

  • 1. Nutrition and Nutrient Review, and Planning Guide – Plant-based or Vegan Diets The 8th annual national Plant-based Prevention of Disease (PPOD) Conference, June 25, 2021 North Carolina State University, Raleigh, NC  Tim Radak, RDN, DrPH, MPH Academic Coordinator - PhD Public Health Program, Core Faculty College of Health Professions Walden University timothy.radak@mail.waldenu.edu
  • 2. Background Current: PhD in Public Health Academic Coordinator/Faculty College of Health Professions, Walden University Previous: Assistant Professor of Nutrition and Dietetic Internship Director College of Health Sciences, Appalachian State University Senior Research Program Manager Cancer Prevention Institute of California, Fremont, CA Director of Nutrition Physician's Committee for Responsible Medicine, Washington DC Loma Linda University – M.P.H.,Dr.PH, RDN -Leader in investigating relationship between vegetarian diet and health and disease outcomes. Post-doc at U of C Davis/WHNRC. Credentialed as a Registered Dietitian Nutritionist for 21 years. John McDougall M.D. Program - Interned Studying, doing research, and publishing in the fields of Nutrition and Chronic Disease for over 20 years with a particular focus on plant foods for minimizing disease and optimizing health. Published in 2013 the first ever entire chapter in academic text on plant based diets for food and ecology text.
  • 3. Nutrition and Nutrient Review, and Planning Guide ⁕Plant-based or Vegan Diets⁕  1) Describe and understand the nutritional and nutrient benefits of a well-planned vegan diet. Why is this diet optimal for health and disease prevention AND the best health-care solution?  2) Describe and understand nutrition and nutrients of potential concern in Omnivore diets in order to attain optimal nutrition status and disease prevention in Plant- based Vegan Diets  3) Discuss available vegan health promotion research and support materials.  Disclosures-- Nothing to disclose
  • 4. First – a moment of recognition
  • 5. First, why a vegan or plant-based diet? A Healthcare Solution – Plant-based Diets Plant Based Diets - Vegetarian/Vegan Diets – Tend to result in:  lower BMI (Crowe, 2013), less caloric intake (Farmer, 2011)  less risk for obesity or overweight (Berkow, 2006, Fraser, 2009)  less incidence or risk of type 2 diabetes (Tonstad, 2011, 2013; Jardine, 2021)  Less risk for dementia, better mood scores, less depression (Giem, 1993; Beezhold, 2010; Beezhold, 2014; Link, 2008; Shen, 2021)  less CHD/IHD (Fraser, 1999, 2009), CVD and CVD/IHD mortality (Key, 1999, Fraser, 2009; Glenn, 2019) . Vegans (males) showed better protection for all-cause mortality, IHD, and CVD (Le, 2014).  less all cause mortality (Orlich, 2013)  less all cause mortality in chronic kidney disease (CKD) patients (Chauveau, 2019)  less cerebrovascular disease or stroke (Kwok, 2014; Kappagoda, 2006; Chiu 2020)  lower incidence of high blood pressure (Crowe, 2013)  lower pro-inflammatory markers and immune biomarkers, C-reactive protein (Craddock, 2019; Yu. 2014; Franco-de-Moraes, 2017; Shah, 2018; Fontana, 2007; Haghighatdoost, 2015; Paalani, 2011; Eichelmann, 2016; Menzel, 2020)
  • 6. First, why a vegan or plant-based diet? A Healthcare Solution – Plant-based Diets Cont’d - Plant Based Diets - Vegetarian/Vegan Diets – Tend to result in:  some of the highest disease fighting biomarkers, increase in phytochemicals/antioxidants (Craig, 2009; Miles, 2019)  increased fiber intake (Rizzo, 2013), less diverticulitis (Crowe, 2011),  more nutrient density (Farmer, 2011)  lower pathogenic dietary factors: saturated fat, cholesterol, LDL-C (Dewell, 2008; Craig, 2010)  less production of TMAO (trimethylamine N-oxide), and HO-1 (heme-oxygenase- 1), both atherosclerotic risk factors (Chiu, 2020; Xu, 2010; Cinegaglia, 2020)  similar bone health to omnivores with adequate calcium (Mangel, 2014) [Dr. Laura Pridemore - Pediatric Evidence of Dietary Effects on Growth Rates, Bone Health and Common Illnesses]  less gallstones/disease (Pixley, 1985; Chang, 2019)  less incidence of gout (Chiu, 2020)  less pollutants in vegan diet (organochlorine concentrations) (Arguin, 2010)
  • 7. First, why a vegan or plant-based diet? A Healthcare Solution – Plant-based Diets Cont’d - Plant Based Diets - Vegetarian/Vegan Diets – Tend to result in:  some of the highest gut equol production (a soy isoflavone metabolite) (Barnard, 2021; Wu, 2016; Setchell, 2006)  less long term hospitalization/medical costs/medication usage (Crowe, 2013; Knutsen,1994; Lin, 2019; Dos Santos, 2021)  increase in longevity (Le, 2014)
  • 8. First, why a vegan or plant-based diet? A Healthcare Solution– Plant-based Diets Plant-Based Diets (Vegan or Vegetarian Diets) - Therapeutic Significant volume of research suggests favorable or positive effects from plant based diets on most chronic diseases or disease risk factors:  CHD/CAD (Koertge, 2003, Esselstyn, 2014)  Hypertension (Berkow, 2005; Lindahl, 1984)  Diabetes (Trapp, 2010; McMacken, 2017; Kelly, 2020)  Diabetic neuropathy (Crane,1994)  Renal Disease/chronic kidney disease (CKD) (Cases,2019; Joshi, 2020)  Obesity (Gardener, 2005, McDougall, 2014)  Metabolic syndrome (Turner-McGrievy, 2014; Marrone, 2021)  Some cancers (Fraser, 2009, Lanou, 2010)  Menopausal Symptoms (Barnard, 2021)
  • 9. First, why a vegan or plant-based diet? A Healthcare Solution– Plant-based Diets Plant-Based Diets (Vegan or Vegetarian Diets) - Therapeutic Significant volume of research suggests favorable or positive effects from plant based diets on most chronic diseases or disease risk factors:  Depression and quality of life (Agarwal, 2014)  Osteoarthritis (Clinton, 2015)  Migraine (Bunner, 2014)  Rheumatoid Arthritis (Alwarith, 2019; Hänninen, 1999; Kjeldsen-Kragh, 1999; McDougall, 2002)  Reducing inflammatory markers (Menzel, 2020; Sutliffe, 2015; Shawh, 2018; Elkan, 2008; Eichelmann, 2016; Jaceldo-Siegl, 2018)  [Dr. Andrew Freeman - Plant-based Diets in 2021: The Data Keep Pouring In]  [Dr. Brie Turner-McGrievy- Past, Present, and Future: Two Decades of Plant- based Diet Research]
  • 10. First, why a vegan or plant-based diet? A Healthcare Solution– Plant-based Diets Plant-Based Diets (Vegan or Vegetarian Diets) - Therapeutic A bit more about reducing inflammatory markers because…  Inflammation linked to diabetes, metabolic syndrome, cardiovascular disease, cancer, rheumatoid arthritis, inflammatory bowel disease, asthma, autoimmune and neurodegenerative disordersand chronic obstructive lung disease (Furman, 2019).  How Beneficial? One example.  Fiber rich plant based diets in gut convert fiber to SCFA which are anti- inflammatory.  And, specialized colonic microbes also break down plant cell walls and release “phytochemicals” such as the polyphenols, anthocyanins, phenolics, and flavins, all of which also have anti-inflammatory, antioxidant, and antineoplastic properties (O'Keefe, 2019).
  • 11. Why a vegan or plant-based diet?  Other non-nutritional reasons too  Baroni, 2007 “vegetarian and vegan diets could play an important role in preserving environmental resources and in reducing hunger and malnutrition in poorer nations”.  [Sherene Chou, MS RDN: “Rethinking Sustainability through Food and Social Justice” ]
  • 12. First, why a vegan or plant-based diet? A Healthcare Crisis Solution  How much does an unhealthy lifestyle (including poor diet) cost us?  Heart Disease: $317 billion  Obesity: $147 billion  Diabetes: $245 billion  Hypertension: $46 billion  Stroke: $34 billion  Cancer care $157 billion
  • 13. First, why a vegan or plant-based diet? A Healthcare Crisis Solution  How much does an unhealthy lifestyle (including poor diet) cost us?  Three-quarters of health care spending goes to treat preventable chronic illnesses (Bodai, 2018; Schmidt, 2016; Chapel, 2017).  85% of the nation’s $3.5 trillion annual health care expenditures are for people with chronic and mental health conditions(Fleischhacker, 2021).  80% of chronic conditions could be avoided through the adoption of healthy lifestyle recommendations (Bodai, 2018).  Recent Kaiser Family Foundation research survey of employers predicts healthcare costs will become unsustainable within the next 5-10 years highlighting a broken healthcare system (Waddill, 2021).
  • 14. First, why a vegan or plant-based diet? A Healthcare Crisis Solution  How much does an unhealthy lifestyle (including poor diet) cost us?  Diet is now the #1 risk factor in the US for mortality and morbidity  US Burden of Disease Collaborators, The State of US Health, 1990-2016: Burden of Diseases, Injuries, and Risk Factors Among US States. JAMA. 2018 Apr 10;319(14):1444-1472.
  • 15. What constitutes a well-planned vegan/plant-based diet  Variety of minimally processed/whole food, nutrient dense fruits, vegetables, beans and legumes, grains, nuts and seeds (minimal processed food)  Variety and diversity in each of the above categories will help ensure adequate protein, calcium, iron, zinc, selenium, and other vitamins, minerals, macronutrients.  Reliable source of Vitamin B-12 (preferably Cyanocobalamin – more stable, better efficacy, and better for oral supplementation than Methylcobalamin types, and caution if supplement via multi-vitamin that includes B-12) (Rizzo, 2016)  Source of Iodine – grains and some vegetables and fruits but is dependent on soil composition. Best option is occasional seaweeds “sea vegetables” (don’t overdo it) which absorb iodine from seawater. Avoid iodized salt due to health effects of sodium. (bonus: EPA, Zinc)
  • 16. What constitutes a well-planned vegan/plant-based diet  Variety of minimally processed/whole food, nutrient dense fruits, vegetables, beans and legumes, grains, nuts and seeds (minimal processed foods)  Source of Vitamin D – main source dependent on sunlight exposure, latitude, age, skin type and degree of exposure i.e. clothes, work in office.  Essential Fatty Acids – moderate Omega 6 intake (easy when limiting refined vegetable oils and processed products containing them), not for inflammation reasons but to reduce effect on Omega 3 incorporation
  • 17. Omega 3 (α-Linolenic acid) – Sample meal without walnuts, chia, flax or algae, or significant oil or fortified foods  Breakfast Oatmeal – 1 ½ cups cooked .063g ½ cup red raspberries .0775g 1 slice wheat bread .045g margarine – none 1 cup soymilk .19g  Lunch Salad – Spinach 2 cups raw .082g Broccoli 1 cup raw .057g Cauliflower ½ cup cooked .104g Tomato 1 cup chopped .005g ½ cup pumpkin seeds .033g Avocado pureed ½ c .128g Italian salad dressing 1 Tbsp .211g Vegetarian baked beans 1 cup .13g  Dinner 1 cup cooked Kale .438g 1 cup cooked kidney beans .375g 1 cup cooked brown rice .022g 1 1/2 cup cooked yam .018 1 oz pretzels .08g 1 cup blueberries .086g  Snack 1 cup cherries .036  Adequate Intakes Males 1.6g/day Females 1.1g/day  Total for sample meal 2.19g
  • 18. What constitutes a well-planned vegan/plant-based diet  How important is variety?  Ex. Intestinal immune cells have specific receptors and proteins for individual phytochemicals found in various F and V that enhance and sustain intestinal immune function within the gut and specific F and V act to reduce risk of colon cancer in separate and specific areas of the colon (Veldhoen , 2012; Annema, 2011; Murakami 2012). See: https://nutritionfacts.org/video/the-broccoli-receptor-our-first-line-of-defense- 2/  [Dr. Leah Frame- Nutrition and the Gut Microbiome]
  • 20. What constitutes a poorly-planned vegan/plant-based diet?  Not following the previous slide recommendations closely enough…  Example: B12 deficiency meta-analysis (Veg/Vegans) 0% - 86.5% adults/elderly, 45% in infants, 0% - 33.3% in children/adolescents, and from 17% -39% among pregnant women (Pawlak, 2014)  “Junk food vegan” Dunk’in Donut to vegan donut, beef burrito to cheese burrito, Breyers ice cream to vegan Breyers, standard cookie to Oreo, etc. Could addictive nature and convenience of SAD foods lend to increased intake as a vegan?  Over reliance on meat analogues – use as transitional/treat  Processed and “fast” food (Sodium ↑ CVD) (Wang, 2020)  Switching from butter to plant-based substitutes (coconut oil) may actually be worse in terms of saturated fat (ex 1 Tsp 12 g sat fat or 58% daily value)
  • 21. What constitutes a poorly-planned vegan/plant-based diet  Research on vegan diets – Are we underestimating the power of plant- based vegan diets from available research studies? How much more improvement in findings and outcomes if participants were truly following a whole foods, minimally processed diet???
  • 22. Possible reasons for a poorly-planned vegan/plant- based diet  Not following meeting a patient where ‘they are’  To understand this it is first helpful to give attention to 1. the diet previous to making the switch to a plant based diet 2. attention to the psychological stage or readiness to make a significant change such as diet.  “The present state of prevailing dietary practices, plant based or otherwise, in the United States and increasing swathes of the world, may be summed up in one word: calamitous. The modern, animal-food-centric, highly processed diet is devastating to planetary and public health alike” (Katz, 2019 -Plant-Based Diets for Reversing Disease and Saving the Planet: Past, Present, and Future) ForwardFood, CBORD, Powering Up with Plant-Strong Programs. ForwardFood.org
  • 23. Possible reasons for a poorly-planned vegan/plant- based diet  Not following meeting a patient where ‘they are’  To understand this it is first helpful to give attention to 1. the diet previous to making the switch to a plant based diet
  • 24. Possible reasons for a poorly-planned vegan/plant- based diet  Not following meeting a patient where ‘they are’  To understand this it is first helpful to give attention to 1. the diet previous to making the switch to a plant based diet  Processed foods (consumption of processed, convenience foods, with a long shelf-life) – dominate the US diet  A national US study found ultra-processed foods (processed foods “engineered” to be high in fat/oils, salt, sugar) made up over half of daily calories and contributed a staggering 89.7% of the energy intake from added sugars (>10% total energy from added sugars) (Martínez Steele, 2016)
  • 25. Possible reasons for a poorly-planned vegan/plant- based diet  Not following meeting a patient where ‘they are’  Sodium, fat, dairy/cheese (casomorphine - opioid peptides), refined carbohydrate (Addictive) – Foods with highest addictive-like qualities: pizza, French fries and cheeseburgers, ice-cream, cookies, potato chips, chocolate (Schulte, 2015)  Added oils (oil is a processed food)  Poor sources/intake of Vitamin B12, D, Zinc, Selenium, Iron, Iodine, Calcium, over reliance on Omega 6  Non diverse dietary intake (that may rely on taking supplements to meet nutrition needs)  Minimal and low diversity: fruit and vegetable, whole grains, legumes  Said another way: maintaining a western style diet minus animal products
  • 26. Possible reasons for a poorly-planned vegan/plant-based diet  Not following meeting a patient where ‘they are’  Despite much nutrition info, most are confused about nutrition, MD/RD’s contradict each other; marketing: main driver of education??  The most important problem is our poor lifestyle choices based on misinformation (Bodai, 2018).  Marketing a known unhealthy product in dietitian magazine and with a slight towards vegetarians…  “Deli meats are pre cooked convenient sources of protein…in fact the Iron and Zinc are more bioavailable than vegetarian sources!  “processed simply means prepared”
  • 27.
  • 28. Fruit and Vegetable intake in USA  Year 2015 - Approximately 12% of US adults consumed the recommended number of servings for fruits (was 13.1% in 2013) (CDC, 2017).  In 2015, more than 37% of adolescents and 40% of adults said they ate fruit less than once a day (CDC, 2017).  2015 - Approximately 9% of US adults consume the recommended number of servings for vegetables (was 8.9% in 2013) (CDC, 2017).  2015, 39% of adolescents and 22% of adults said they ate vegetables less than once a day (CDC, 2017).  91% did not meet vegetable intake recommendations!
  • 29. Vegetable intake in USA  Quality and Quantity are both important…  Half of the vegetable intake (51%) comes from potatoes or tomatoes, most of which is in the form of fried potatoes or chips or pizza or pasta sauce (Guthrie, 2014).
  • 30. Fruit and Vegetable intake in USA – lacking diversity USDA Economic Research Service –Ag and Food Statistics, April 2017 https://www.ers.usda.gov/webdocs/publications/83344/ap-075.pdf?v=42853
  • 31. Possible reasons for a poorly-planned vegan/plant- based diet  Psychological readiness or willingness to change also affects quality of vegan/plant-based diets/habits.  No amount of pamphlets, facts, and discussion are effective unless we are meeting a patient where they are psychologically. Prochaska, J.O., DiClemente, C.C., & Norcross, J.C. (1992). In search of how people change: Applications to the addictive behaviors. American Psychologist, 47, 1102-1114. PMID: 1329589. [Round Table: What Blocks the Benefits of Plant-based Whole Foods? Not Affordable? Poor Access? Seen as Bland/Boring? Chair: Renae Thomas, MD, Lily Correa, MPH RDN DipACLM, Dawn Hilton-Williams, BA]
  • 32. Possible reasons for a poorly-planned vegan/plant- based diet  Impact of COVID-19. During pandemic 40% of Americans struggled with mental health in some form (Czeisler, 2020).  Will the US be similar to Poland when data arrives?  Dietary Choices and Habits during COVID-19 Lockdown: Experience from Poland - Aleksandra Sidor , Piotr Rzymski  Over 43.0% and nearly 52% reported eating and snacking more, respectively, and these tendencies were more frequent in overweight and obese individuals. Almost 30% and over 18% experienced weight gain (mean ± SD 3.0 ± 1.6 kg) and loss (-2.9 ± 1.5 kg), respectively. Overweight, obese, and older subjects (aged 36-45 and >45) tended to gain weight more frequently, whereas those with underweight tended to lose it further. Increased BMI was associated with less frequent consumption of vegetables, fruit, and legumes during quarantine, and higher intake of meat, dairy, and fast-foods. An increase in alcohol consumption was seen in 14.6%, with a higher tendency to drink more found among alcohol addicts  Recent Investigations of Public Health Nutrition and COVID-19 in Developed Countries – Caroline Um – June 2021 American Society for Nutrition - decrease in healthy foods, vegetables whole grains in US
  • 33. Possible reasons for a poorly-planned vegan/plant- based diet  Impact of COVID-19. Some positive news Those following a plant-based diet had 73 percent lower odds of experiencing a 'moderate-to-severe' course of COVID-19 compared to meat-eaters  Actor Bronson Pinchot During quarantine – removed all junk food from refrigerator and pantry and replaced with healthy vegan food, minimal exercise: 60#. Struggled with weight fluctuating since age 6 and for first time is stable from following vegan diet.
  • 34. Figure Other considerations when recommending plant-based diets Radnitz C, Beezhold B, DiMatteo J. Investigation of lifestyle choices of individuals following a vegan diet for health and ethical reasons. Appetite. 2015 Jul;90:31-6. doi: 10.1016/j.appet.2015.02.026. Epub 2015 Feb 25. •Meeting a patient where they “are” •Recent international online survey, Fruit and Vegetable Intake For from US. 245 vegans (45 for health reasons (HEA), 201 for ethical reasons (ETH)) •Very good intakes overall. Fruit intake significantly greater in those who choose to follow vegan diet for health reasons
  • 35. Dietary Guidelines and Diagrams  Adapt existing and possibly familiar guidelines/diagrams - A Plant Based Diet more closely resembles what the current dietary recommendations are for intakes of fruits, vegetables, whole grains, beans/legumes, intake of saturated fats, than any other diet (Farmer, 2011).  Add: healthy seasonings i.e. herbs/spices/nutritional yeast, Braggs or coconut aminos, balsamic vinegar  Dr. McDougall sauces/dressings: https://www.drmcdougall.com/health/education/recipes/mcdougall-recipes/?cat- id=9&cat-name=Dressings+%26+Sauces  Starting with the Dietary Guidelines for Americans 2015–2020: Healthy Vegetarian Eating Pattern “This Pattern can be vegan if all dairy choices are comprised of fortified soy beverages (soymilk) or other plant-based dairy substitutes.” p.86
  • 36. Plant based Resources  Modified Food Guide Pyramid for Lactovegetarians and Vegans - Colleen A. Venti and Carol S. Johnston http://jn.nutrition.org/content/132/5/1050.full.pdf+html  Vegetarian Food Guide Pyramid – Loma Linda University http://www.vegetariannutrition.org/6icvn/food- pyramid.pdf  Vegetarian Food Guide Pyramid – Oldways Preservation Trust https://oldwayspt.org/traditional- diets/vegetarian-vegan-diet  Academy of Nutrition and Dietetics – Position Paper on Vegetarian Diets https://www.eatrightpro.org/-/media/eatrightpro-files/practice/position-and-practice-papers/position-papers/vegetarian-diet.pdf  USDA Food and Nutrition Center – Vegetarian Nutrition https://www.nal.usda.gov/fnic/vegetarian- nutrition  PCRM - Nutrition Guide for Clinicians https://nutritionguide.pcrm.org/nutritionguide  Tuso, PJ, et al. Nutritional Update for Physicians: Plant-Based Diets. Perm J. 2013 Spring; 17(2): 61–66  Hever J. Plant-Based Diets: A Physician’s Guide. Perm J. 2016 Summer; 20(3): 15-082.  Bodai, et al. Lifestyle Medicine: A Brief Review of Its Dramatic Impact on Health and Survival. Perm J. 2018;22:17-025  Counseling Vegan Clients – Matt Ruscigno, MPH, RD - Today's Dietitian https://www.todaysdietitian.com/newarchives/1017p20.shtml  The Plantrician Project -PlantPure Rx – 10 day food-supported immersion program that introduces patients to the health benefits of a whole food, plant-based diet. https://www.plantpurenation.com/pages/plantpure-rx
  • 37. Plant based Resources  Excellent free Print Resources for patients from American College of Lifestyle Medicine https://www.lifestylemedicine.org/ACLM/Tools_and_Resources/Print_Resources.aspx
  • 38. In the right direction  Major organizations have endorsed/supported plant-based diets – American Institute For Cancer Research – Academy Of Nutrition And Dietetics – American Heart Association – American College of Cardiology/AHA - clinical practice guidelines - Primary prevention of CVD – American Diabetes Association – Kaiser Permanente – Aramark - serves nearly 2 billion meals/yr - launched a major plant-forward initiative  The American Medical Association’s House of Delegates has adopted a resolution calling on hospitals to provide plant-based meals and remove processed meats from menus. And the AMA has also written a letter last year to the USDA to indicate in the dietary guidelines that meat and dairy are optional.  In Lebanon, a hospital a few months ago become the first to use a 100% entirely vegan menu
  • 39. In the right direction  Nielsen reports (prior to COVID-19) that more than 39 percent of consumers in the US are trying to incorporate more plant-based foods into their diet.  Interest continues to ↑ (environment, health, ethics, animal welfare). Sales of plant-based foods ↑ 27% in 2020 [Lily Correa - Guiding Patients’ Long-term Success, One Plate at a Time] [Jasmol Sardana - “Creating Lasting Behavior Change: How to Speak with Our Patients about Diet and Lifestyle”]
  • 40. In the right direction • This article provides insights to aspects of diet and chronic illness and discusses how the plant-based movement could redefine current understanding of chronic disease. The ethical justifications for recommending of a plant-based diet are analyzed. • The article concludes that not advocating for plant-based nutrition is unethical and harms the planet and patients alike. Storz MA. Will the plant-based movement redefine physicians' understanding of chronic disease? New Bioeth. 2020 Jun;26(2):141-157.
  • 41. Nutrition and Nutrient Review, and Planning Guide – Plant-based or Vegan Diets The 8th annual national Plant-based Prevention of Disease (PPOD) Conference, June 25, 2021 North Carolina State University, Raleigh, NC  Tim Radak, RDN, DrPH, MPH Academic Coordinator - PhD Public Health Program, Core Faculty College of Health Professions Walden University timothy.radak@mail.waldenu.edu
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  • 48. References  Menzel J, Jabakhanji A, Biemann R, Mai K, Abraham K, Weikert C. Systematic review and meta- analysis of the associations of vegan and vegetarian diets with inflammatory biomarkers. Sci Rep. 2020;10(1):21736. Published 2020 Dec 10. doi:10.1038/s41598-020-78426-8  Miles FL, et al. Plasma, Urine, and Adipose Tissue Biomarkers of Dietary Intake Differ Between Vegetarian and Non-Vegetarian Diet Groups in the Adventist Health Study-2. J Nutr. 2019 Apr 1;149(4):667-675.  Murakami A, Ohnishi K. Target molecules of food phytochemicals: food science bound for the next dimension. Food Funct. 2012 May;3(5):462-76.  O'Keefe SJD. Plant-based foods and the microbiome in the preservation of health and prevention of disease. Am J Clin Nutr. 2019;110(2):265-266. doi:10.1093/ajcn/nqz127  Orlich MJ, et al. Vegetarian dietary patterns and mortality in Adventist Health Study 2. JAMA Intern Med. 2013 Jul 8;173(13):1230-8.  Paalani, M, Lee JW, Haddad E, Tonstad S. Determinants of inflammatory markers in a Bi-ethnic population. Ethn. Dis. 2011, 21, 142–149.  Pawlak R, Lester SE, Babatunde T. The prevalence of cobalamin deficiency among vegetarians assessed by serum vitamin B12: a review of literature. Eur J Clin Nutr. 2014 May;68(5):541-8.  Pixley F, Wilson D, McPherson K, Mann J. Effect of vegetarianism on development of gall stones in women. BMJ. 1985;291:11–12.  Prochaska, J.O., DiClemente, C.C., & Norcross, J.C. (1992). In search of how people change: Applications to the addictive behaviors. American Psychologist, 47, 1102-1114. PMID: 1329589.  Rizzo G, Laganà AS, Rapisarda AM, et al. Vitamin B12 among Vegetarians: Status, Assessment and Supplementation. Nutrients. 2016;8(12):767. Published 2016 Nov 29. doi:10.3390/nu8120767  Rizzo NS, et al. Nutrient profiles of vegetarian and nonvegetarian dietary patterns. J Acad Nutr Diet. 2013 Dec;113(12):1610-9.  Schmidt H. Chronic Disease Prevention and Health Promotion. 2016 Apr 13. In: H. Barrett D, W. Ortmann L, Dawson A, et al., editors. Public Health Ethics: Cases Spanning the Globe [Internet]. Cham (CH): Springer; 2016. Chapter 5. Available from: https://www.ncbi.nlm.nih.gov/books/NBK435779/ doi:
  • 49. References  Schulte EM, Avena NM, Gearhardt AN. Which foods may be addictive? The roles of processing, fat content, and glycemic load. PLoS One. 2015 Feb 18;10(2):e0117959.  Setchell KD, Cole SJ. Method of defining equol-producer status and its frequency among vegetarians. J Nutr. 2006 Aug;136(8):2188-93  Shah B, Newman JD, Woolf K, Ganguzza L, Guo Y, Allen N, Zhong J, Fisher EA, Slater J. Anti- Inflammatory Effects of a Vegan Diet Versus the American Heart Association-Recommended Diet in Coronary Artery Disease Trial. J Am Heart Assoc. 2018 Dec 4;7(23):e011367.  Shen YC, Chang CE, Lin MN, Lin CL. Vegetarian Diet Is Associated with Lower Risk of Depression in Taiwan. Nutrients. 2021 Mar 24;13(4):1059.  Sidor A, Rzymski P. Dietary Choices and Habits during COVID-19 Lockdown: Experience from Poland. Nutrients. 2020 Jun 3;12(6):1657.  Sutliffe JT, Wilson LD, de Heer HD, Foster RL, Carnot MJ. C-reactive protein response to a vegan lifestyle intervention. Complement Ther Med. 2015 Feb;23(1):32-7.  Tonstad S, et al. Type of Vegetarian Diet, Body Weight, and Prevalence of Type 2 Diabetes. Diabetes Care. 2009 May; 32(5): 791–796.  Tonstad S, Stewart K, Oda K, Batech M, Herring RP, Fraser GE. Vegetarian diets and incidence of diabetes in the Adventist Health Study-2. Nutr Metab Cardiovasc Dis. 2013 Apr;23(4):292-9.  Trapp CB, Barnard ND. Usefulness of vegetarian and vegan diets for treating type 2 diabetes. Curr Diab Rep. Apr 2010;10(2):152-8.  Turner-McGrievy G, Harris M. Key elements of plant-based diets associated with reduced risk of metabolic syndrome. Curr Diab Rep. 2014 Sep;14(9):524.  US Burden of Disease Collaborators, et al. . The State of US Health, 1990-2016: Burden of Diseases, Injuries, and Risk Factors Among US States. JAMA. 2018 Apr 10;319(14):1444-1472.  Veldhoen M. Direct interactions between intestinal immune cells and the diet. Cell Cycle. 2012 Feb 1;11(3):426-7.  Waddill, K. (2021, April 29). Employers: Healthcare Spending Is on an Unsustainable Trajectory.
  • 50. References  Wang YJ, Yeh TL, Shih MC, Tu YK, Chien KL. Dietary Sodium Intake and Risk of Cardiovascular Disease: A Systematic Review and Dose-Response Meta-Analysis. Nutrients. 2020 Sep 25;12(10):2934.  Xu J, Yang S, Cai S, Dong J, Li X, Chen Z. Identification of biochemical changes in lactovegetarian urine using 1H NMR spectroscopy and pattern recognition. Anal Bioanal Chem. 2010 Feb;396(4):1451- 63.  Yu X, Huang T, Weng X, Shou T, Wang Q, Zhou X, Hu Q, Li D. Plasma n-3 and n-6 fatty acids and inflammatory markers in Chinese vegetarians. Lipids Health Dis. 2014 Sep 29;13:151. doi: 10.1186/1476-511X-13-151. . .

Editor's Notes

  1. What a true pleasure it is to introduce and launch the 8th annual PPOD conference. While this in virtual format, we should still be able to maximize learning and find many opportunities to engage and participate. . You’ll find presenters to be approachable (even in virtual format) Welcome everyone and if you haven't attended a PPOD conference, you will find the next few days full of experts sharing education, research, community and bringing awareness to the benefits of evidence-based well planned plant based diets
  2. Started an interest in plant based diets roughly 30 years ago and wanted to determine if there was science to back up the assertions of health benefits. 15 yrs ago –residency for McDougal
  3. Slides will be available to participants
  4. With just 5% of the global population, The U.S. accounts for 15% of all deaths 602K from COVID-19 of the total 3.8 million, tremendous toll
  5. Plant Based Diets – Eating plant-based provides and an additive effect – address a multitude of health indicators or disease risks at the same time  C-reactive protein increases when there's inflammation in the body.
  6. Plant Based Diets – in addition to grater intake of Fruits, Vegetables, Whole Grains, Beans (Clary, 2014), plant based diets tend to….
  7. Equol - anticancer properties - soybeans and green tea is reported to increase equol production [87]. 87. Miyanaga N., Akaza H., Takashima N., Nagata Y., Sonoda T., Mori M., Naito S., Hirao Y., Tsukamoto T., Fujioka T. Higher consumption of green tea may enhance equol production. Asian Pac. J. Cancer Prev. 2003;4:297–301 
  8. We’ll hear more about breast cancer and plant-based diets by Dr. Amber Oman and Dr Renae Thomas… Istockphoto.com/vaaseenaa CHD – build up of plaque/hardening of arteries CHD/CAD used interchangeably
  9. We’ll hear more about the latest data on plant-based diets by Dr. Freeman and Dr. Turner-McGrievy tomorrow… I consider a well planned vegan diet to be “an Anti-inflammatory Diet”  Wium-Andersen, 2013: C-reactive protein (CRP), a marker of inflammation, - higher the blood levels of CRP, the more likely someone was to use antidepressants or be hospitalized for depression.
  10. We’ll hear more about the latest data on plant-based diets by Dr. Freeman and Dr. Turner-McGrievy tomorrow… I consider a well planned vegan diet to be “an Anti-inflammatory Diet”  Wium-Andersen, 2013: C-reactive protein (CRP), a marker of inflammation, - higher the blood levels of CRP, the more likely someone was to use antidepressants or be hospitalized for depression.
  11. Environmental, global health, sustainable food production, climate change…… chart from Baroni L, Cenci L, Tettamanti M, Berati M. Evaluating the environmental impact of various dietary patterns combined with different food production systems. Eur J Clin Nutr. 2007;61(2):279–186 The Ethics of What We Eat: Why Our Food Choices Matter 2007 Diet for a Hot Planet: The Climate Crisis at the End of Your Fork and What You Can Do about It 2011
  12. https://www.cdc.gov/chronicdisease/resources/publications/aag/heart-disease-stroke.htmCDC Heart Disease and Stroke Prevention at a glance 2016 https://www.cdc.gov/chronicdisease/overview/index.htm https://www.ncbi.nlm.nih.gov/books/NBK435779/ https://www.cdc.gov/bloodpressure/faqs.htm https://www.cdc.gov/stroke/facts.htm https://sites.tufts.edu/nutritionadvisory/files/2021/01/WP_Executive-Summary_Final.pdf
  13. https://healthpayerintelligence.com/news/employers-healthcare-spending-is-on-an-unsustainable-trajectory https://www.cdc.gov/chronicdisease/resources/publications/aag/heart-disease-stroke.htmCDC Heart Disease and Stroke Prevention at a glance 2016 https://www.cdc.gov/chronicdisease/overview/index.htm https://www.ncbi.nlm.nih.gov/books/NBK435779/ https://www.cdc.gov/bloodpressure/faqs.htm https://www.cdc.gov/stroke/facts.htm https://sites.tufts.edu/nutritionadvisory/files/2021/01/WP_Executive-Summary_Final.pdf
  14. https://healthpayerintelligence.com/news/employers-healthcare-spending-is-on-an-unsustainable-trajectory https://www.cdc.gov/chronicdisease/resources/publications/aag/heart-disease-stroke.htmCDC Heart Disease and Stroke Prevention at a glance 2016 https://www.cdc.gov/chronicdisease/overview/index.htm https://www.ncbi.nlm.nih.gov/books/NBK435779/ https://www.cdc.gov/bloodpressure/faqs.htm https://www.cdc.gov/stroke/facts.htm https://sites.tufts.edu/nutritionadvisory/files/2021/01/WP_Executive-Summary_Final.pdf
  15. Iodine – particularly important for Preg women as most are unaware of iodine need and many prenatals don’t contain it https://www.thyroid.org/patient-thyroid-information/ct-for-patients/may-2019/vol-12-issue-5-p-3-4/ Minimal Processed Foods, and plant food minimally processed. Also has Vit C and iron (more bioavailable) 2.4 μg/day. Cases of B12 inadequacy – should not occur and may be representative of how well vegans follow dietary guidance. 2 types: Cyanocobalamin (better for oral supplemntation) better than Methylcobalamin(less stable and effecatuious) Multivitamins – some minerals/vit may reduce absorption/transport of B12 Ocean water deposited on land from rainwater. Potatoes, prunes, kale, whole grains, strawberries World Health Organization, RDAfor iodine for the average person is 150 micrograms (mcg).  endemic goiter, learning disabilities, and hypothyroidism – does long term followers of vegan diets have these? NO! Eat fortified foods two or three times a day to get at least three micrograms (mcg or µg) of B12 a day OR  Take one B12 supplement daily providing at least 10 micrograms OR  Take a weekly B12 supplement providing at least 2000 micrograms. Plant based diet – discourage animal products and optimally no animal products
  16. 600-800 IU/day **Vitamin D is available as colecalciferol (vitamin D3) ergocalciferol (vitamin D2) - Taking too many vitamin D supplements over a long period of time can cause too much calcium to build up in the body (hypercalcaemia). This can weaken the bones and damage the kidneys and the heart. https://www.nhs.uk/conditions/vitamins-and-minerals/vitamin-d/ **Omega 6 levels will naturally be ok (fall into place) with limiting processed foods arachidonic acid not linoleic acid is inflammatory - also LA reduces cholesterol and is inversely related to CHD risk (Farvid, 2014)
  17. Nature has provided a variety of different sources of omega 3 both on land and in the ocean Cabbage, leafy greens, arugula/romaine/Mustard greens, squashes, beets, corn, garbanzos, beans – Navy beans ½ cup, 37-54% ALA Kidney beans ½ cup, 20-30% ALA
  18. Veldhoen, M. (2012). Direct interactions between intestinal immune cells and the diet. Cell Cycle, 11(3), 426–427. Green vegetables are actually required to maintain intestine immune cells!
  19. Ideally could look like this! New and Kind and Enlightened Diet – Food Magazine Carbohydrates: 45–65% Fat: 25–35% Protein: 20–30% of total daily calories Mcdougall 6-14% Protein
  20. There is a vegan equivalent for almost every unhealthy food! Not trying to be the vegan police here and it is about moderation. 70% of supermarket aisles are filled with unhealthy foods plant-based butters are high in coconut oil, which contains 50 percent more saturated fat than regular butter. Saturated fat has been linked to a higher risk of heart disease, high blood pressure, and ultimately more incidents of heart attacks and strokes. Palm oil too!
  21. As an aside
  22. Katz – preventive physician Half of grocery store promotions are for unhealthy foods https://inews.co.uk/news/health/supermarkets-discounts-unhealthy-food-obesity-which-16617
  23. People believe Meat = Protein Dairy = Ca Fish = EPA/DHA Omega 3s
  24. Average dietary content of added sugars and proportion of individuals consuming more than 10% of total energy from added sugars. UPF’s “ industrial formulations”, besides salt, sugar, oils and fats, include substances not used in culinary preparations ultra-processed foods contain large amounts of fat and refined carbs, a potent combination that is rarely seen in naturally occurring foods that humans evolved to eat
  25. processed foods with added sugars and fat, could be as addictive as drugs [6,7], acting via the same neurocognitive and hedonic processes [8,9]. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7699750/ Foods, nutrition, what we need to eat, all confusing to consumer – much do to marketing, special interests promoting their product/food group LOOK at fish oil supplements as an example
  26. Marketing a known unhealthy product in dietitian magazine and with a slight towards vegetarians! “Deli meats are pre cooked convenient sources of protein…in fact the Iron and Zinc are more bioavailable than vegetarian sources!
  27. Looking at Food At Home Purchases Only- USDA Economic Research Service and USDA Center for Nutrition and Policy Promotion Liberal Food Plan Data http://www.washingtonpost.com/blogs/wonkblog/wp/2014/06/18/the-rise-of-processed-and-fast-foods-and-the-ever-expanding-american-waistline/ http://www.ers.usda.gov/media/945051/eib102.pdf *Ferdman, RA. June 18, 2014. How the American Diet Has Failed. Washington Post. Retrieved from: http://www.washingtonpost.com/blogs/wonkblog/wp/2014/06/18/the-rise-of-processed-and-fast-foods-and-the-ever-expanding-american-waistline/ *Volpe, Richard, and Abigail Okrent. Assessing the Healthfulness of Consumers’ Grocery Purchases, EIB-102, U.S. Department of Agriculture,Economic Research Service, November 2012. http://www.ers.usda.gov/media/945051/eib102.pdf
  28. US Dietary recommendations suggest: -may be time for more recent research given the rapid popularity of plant based diets…… https://www.cdc.gov/nutrition/downloads/state-indicator-report-fruits-vegetables-2013.pdf https://www.cdc.gov/mmwr/preview/mmwrhtml/mm6426a1.htm
  29. US Dietary recommendations suggest: 2.5 cups veg and 2 cups per day fruit five vegetable subgroups—dark green, red and orange, legumes (beans and peas), starchy, and other.[10] These include all fresh, frozen, canned, and dried options in cooked or raw forms, including vegetable juices
  30. From perspective of pounds consume. Note orange and apple are from juices EXCEPTION: Latinos eat more fruits and vegetables than other groups, about six or seven servings a day, but still don’t even make the recommended minimum of nine daily servings
  31. Some elements of the SAD are addictive (Prochaska developed model for addictive behaviors) Round table to discuss behavioral aspects
  32. https://nutrition.org/new-research-shows-trend-toward-unhealthy-eating-during-pandemic/ https://pubmed.ncbi.nlm.nih.gov/32503173/ https://www.cdc.gov/mmwr/volumes/69/wr/mm6932a1.htm During pandemic – more online grocery – less junk food purchased – grocerr stores arrange unhealthy products to be most visible https://www.jneb.org/article/S1499-4046(21)00081-6/fulltext
  33. those who reported following low-carbohydrate, high-protein diets, such as keto or paleo, which are typically high in animal-based protein, were almost four times more likely to experience a moderate-to-severe form of COVID-19. https://www.nickiswift.com/368851/how-bronson-pinchot-lost-60-pounds/ dropped 60 pounds in only six months ABCs Perfect Strangers Those following a plant-based diet had 73 percent lower odds of experiencing a 'moderate-to-severe' course of COVID-19 compared to meat-eaters
  34. Only looked at F and V – unsure if transfers to rest of diet US Dietary Guidelines Fruit, 1.5 to 2 cup equivalents Veg 2.5 to 3 cup equivalents
  35. A Healthy Vegetarian Eating Pattern replaces the previous Lactoovo Vegetarian Adaptation of the USDA Food Patterns from the 2010 Dietary Guidelines Ex.PCRM Power Plate Ex. Plant based Health Professionals UK https://plantbasedhealthprofessionals.com/wp-content/uploads/HE-KEY-BENEFITS-OF-PLANT-BASED-NUTRITION.pdf
  36. PCRM Power Plate
  37. PCRM Power Plate
  38. https://nielseniq.com/global/en/insights/analysis/2018/plant-based-food-options-are-sprouting-growth-for-retailers/ https://www.ahajournals.org/doi/10.1161/CIR.0000000000000678 https://www.heart.org/en/healthy-living/healthy-eating/eat-smart/nutrition-basics/how-does-plant-forward-eating-benefit-your-health https://newsroom.heart.org/news/eating-more-plant-based-foods-may-be-linked-to-better-heart-health#:~:text=%E2%80%9CThe%20American%20Heart%20Association%20recommends,clogging%20saturated%20and%20trans%20fats. https://policysearch.ama-assn.org/policyfinder/detail/Healthy%20Food%20Options%20in%20Hospitals%20H-150.949?uri=%2FAMADoc%2FHOD.xml-0-627.xml https://pcrm.widen.net/s/m2mwbvtbpg/2020-8-13-american-medical-association-dietary-guidelines-letter https://www.aramark.com/about-us/blog/going-plant-forward-in-our-kitchens https://www.aramark.com/about-us/news/aramark-general/beyond-meat-products-help-aramark-drive-innovation https://www.pcrm.org/news/health-nutrition/american-diabetes-association-promotes-plant-based-diets https://www.instagram.com/p/CL34isaMYcp/
  39. https://nielseniq.com/global/en/insights/analysis/2018/plant-based-food-options-are-sprouting-growth-for-retailers/ plantbasedfoods.org/retail-sales-data  https://www.ahajournals.org/doi/10.1161/CIR.0000000000000678 https://www.heart.org/en/healthy-living/healthy-eating/eat-smart/nutrition-basics/how-does-plant-forward-eating-benefit-your-health https://newsroom.heart.org/news/eating-more-plant-based-foods-may-be-linked-to-better-heart-health#:~:text=%E2%80%9CThe%20American%20Heart%20Association%20recommends,clogging%20saturated%20and%20trans%20fats. https://policysearch.ama-assn.org/policyfinder/detail/Healthy%20Food%20Options%20in%20Hospitals%20H-150.949?uri=%2FAMADoc%2FHOD.xml-0-627.xml https://pcrm.widen.net/s/m2mwbvtbpg/2020-8-13-american-medical-association-dietary-guidelines-letter https://www.aramark.com/about-us/blog/going-plant-forward-in-our-kitchens https://www.aramark.com/about-us/news/aramark-general/beyond-meat-products-help-aramark-drive-innovation https://www.pcrm.org/news/health-nutrition/american-diabetes-association-promotes-plant-based-diets
  40. Perhaps a very revealing and telling sign of where the plant-based movement is headed and what stage of the process we are at is this article. We may be at a point where it is an ethically bound duty as a healthcare worker to promote plant-based diets. Are you ready?