Pharmaceutical Engineering Size reduction

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10.  Advantages :-
 Content Uniformity
 Uniform Flow
 Effective Drying
 Increase Surface Area/Viscosity
 Uniform Mixing and Drying
 Improve Rate Of Adsorption
 Improve Dissolution Rate
 Disadvantages :-
 Change In Colour
 Loss Of Aromatic Principle
 Drug Degradation
 Problem Of Preservation

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18. Rittinger’s law
Kick’s law
Bond’s law
Used to predict the energy
requirements for size reduction

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20.  WORKING :-

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