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Biology theory 2
1. University of Duhok
College of Health Sciences
Dep. of Medical Laboratories
Biology/1st Stage
Lecture 2
Dr: Shameeran S. Ismael
BVM & S, M.Sc Medical Microbiology(Parasitology),
PhD Molecular Parasitology
2. Size of cell
• Cells vary in size. Most cells are very small
(microscopic), some may be very large
(macroscopic).
• The unit used to measure size of a cell is
micrometer:
1 µm = 1/1000 millimeter
3. Smallest cell is Mycoplasma
it is size: 0.1 µm
Largest cell is Ostrich egg it
is size: 18 cm
5. Shape of cell
• Cells vary in shape.
• Variation depends mainly upon the function of
cells.
• Some cells like Euglena and Amoeba can
change their shape, but most cells have a fixed
shape.
6. • Human RBCs are circular
biconcave for easy passage
through human capillaries.
• Nerve cells are branched to
conduct impulses from one
point to another.
• Human WBCs can change
their shape to engulf the
microorganisms that enter
the body.
10. 10
Eukaryotes
• Cells that have a nucleus and
membrane-bound organelles
• Includes protists, fungi, plants, and
animals
• More complex type of cells
13. 13
1.Cell or Plasma Membrane
Outside
of cell
Inside
of cell
(cytoplasm)
Cell
membrane
Proteins
Protein
channel Lipid bilayer
Carbohydrate
chains
• Composed of double layer of phospholipids and proteins
• Surrounds outside of all cells
• Controls what enters or leaves the cell
• Living layer
14. Functions:
• Maintains shape & size of the cell
• Separates cell from outside
• Protects internal contents of the cell
• Recognizes signals from other cells
• allows communication between cells
• Regulates entry and exit of substances in and
out of the cell (O2, CO2, food, H2O, nutrients
And waste)
17. 17
Phospholipids
• Heads contain glycerol & phosphate
and are hydrophilic (attract water)
• Tails are made of fatty acids and are
hydrophobic (repel water)
• Make up a bilayer where tails point
inward toward each other
• Can move laterally to allow small
molecules (O2, CO2, & H2O to enter)
18. 18
The Cell Membrane is Fluid
Molecules in cell membranes are constantly
moving and changing
19. 19
Cell Membrane Proteins
• Proteins help move large molecules or aid in
cell recognition
• Peripheral proteins are attached on the
surface (inner or outer)
• Integral proteins are embedded completely
through the membrane
20. Cell wall
• Non-living layer
• Found outside of the cell membrane
• Supports and protects cell
• Found in plants, fungi, & bacteria
• Rigid and sometimes flexible
• Made up of cellulose, hemicellulose and
pectin
• May be thin or thick, multilayered structure
22. 2. Nucleus
• Dense spherical body located near the centre
of the cell. Is a Control center of the cell
• Present in all cells except red blood cells and
sieve tube cells
• Most of the cells are uninucleated (having only
one nucleus)
• Few types of cells have more than one nucleus
(skeletal muscle cells)
23. Surrounded by a double membrane called the
nuclear membrane or nuclear envelope.
Nuclear envelope has thousands of pores
which allow material to move into and out of
the nucleus.
24. • Contains DNA which contains the coded
instructions for making proteins which are the
molecules that do “everything”.
• There are thread-like material in the nucleus is
called chromatin which is DNA wrapped around
protein.
• Usually looks like this but as a cell prepares to
divide, chromatin condenses to form
chromosomes.
27. 27
• Jelly-like substance
enclosed by cell
membrane
• Provides a medium for
chemical reactions to
take place
3.Cytoplasm of a Cell
cytoplasm
28. Cytoplasm: is everything inside the cell
membrane, except the nucleus. Contains
organelles to carry out specific jobs
Organelles: means little organ
Cytosol: or the intracellular fluid is the liquid
found inside cells
30. 1.Endoplasmic Reticulum (ER):
• The internal membrane system of the cell
• It is a large network of membrane that builds
cell material.
• It looks like long tubules or bags.
• It encloses fluid filled lumen
• Helps move substances within cells
31. There are two types:
1.Rough endoplasmic reticulum:
• It has ribosomes attached to its surface
• That functions in protein synthesis
2.Smooth endoplasmic reticulum::
• It doesn't have ribosomes attached to its
surface.
• That function in lipid synthesis
34. Function of Endoplasmic Reticulum
• It is associated with synthesis, storage and
transport of metabolic products
• It gives internal support to the colloidal matrix
• It helps in the formation of new cell
membrane
• Rough endoplasmic reticulum: It is concerned
with the protein synthesis
• Smooth endoplasmic reticulum: It is concerned
with enzymes and lipid formation
35. Ribosomes
• Ribosomes are dense spherical granular
particle which move freely in the matrix. site
of protein synthesis
• They are present in the cytoplasm as well as
inside the nucleus
• Ribosomes is made up of numerous proteins
and RNA
• Found either free or bound to endoplasmic
reticulum
36. Function of Ribosomes
• They play an important role in protein
synthesis.
• It helps in storage modification and packaging
of products in the vesicles.
• It involves in the synthesis of lysosomes.