2. BLOOD
PLASMA : FLUID PORTION
FORMED ELEMENTS : RED BLOOD CELLS
(ERYTHROCYTES)
WHITE BLOOD CELLS
PLATELETS
3.
4. RBC MORPHOLOGY
SHAPE :
o Biconcave and disc shaped –Thin center and thick periphery
o Center portion is pale –occupies 1/3rd of cell’s diameter
5.
6. ADVANTAGES OF BICONCAVE SHAPE
Can easily squeeze through the capillaries while passing
without getting damaged.
Provides large surface area for absorption and removal of
different substances.
Helps in equal and rapid diffusion of O2 and other
substances into the interior of the cell.
10. No nucleus
No organelles
Cell membrane contains a contractile protein, SPECTRIN,
maintain shape and flexibility of RBC membrane
120 day life span
Filled with Hemoglobin , transports O2
STRUCTURE
11. ANISOCYTOSIS :
Variation in the size of RBC.
It may be:
MICROCYTIC: smaller, <6 micrometer
MACROCYTIC : larger, > 8.5 micrometer
22. 3. SPHEROCYTES
Smaller than normal
Absent central pallor
Found in Hereditary spherocytosis
23.
24. 4. TARGET CELLS /LEPTOCYTES
Central round area of staining surrounded by a
ring of pallor. And then an outer border which is
stained again.
Thalassemia
Liver disase
Post splenectomy
25.
26. 4. SICKLE CELLS
Elongated and distorted like a sickle
Tapered at both ends and loss of central
pallor
Sickle cell disease
34. 8. TEAR DROP CELLS ( DACRYOCYTE )
Thalassemia major
Myeloproliferative syndrome
35.
36. 9. STOMATOCYTES
It has central slit / stoma (mouth)
Normal people
Cardiovascular and pulmonary disorder
Hereditary
Alcoholism, Liver disease
37.
38.
39. MORPHOLOGICAL CLASSIFICATION OF ANEMIA
1.MICROCYTIC HYPOCHROMIC :
• Iron deficiency anemia
• Thalassemia
• Anemia of chronic disease