2. They use the enzyme, Reverse Transcriptase for production of DNA from RNA

3. Reverse Transcriptase is used after the Retrovirus has entered the host cell used to make a DNA copy of their RNA genes.

5. Single-stranded DNA copies of the mRNA are made using reverse transcriptase called cDNA.

6. DNA polymerase is used to convert the single-stranded DNA into double stranded DNA produces genes that can be transferred into another organism.

8. IF disease caused by a recessive allele… fully functional dominant allele inserted into defective cells.

10. Body cells altered do not develop into gametes.

11. Often large numbers of cells will be altered.

12. Genetic disease may be cured in treated individual

13. Can pass to offspring

14. Germ-line therapy:

15. Sperm or egg cells treated (or cells that will divide to produce sperm or egg cells)

16. Disease will not pass onto offspring