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TOPIC

2

CAUSES OF HEARING
IMPAIRMENT
Outer and Middle Ear Disorders




Structural defects due to embryologic
malformations
Structural changes secondary to
infection or trauma
Outer Ear Disorders


Microtia and atresia
Microtia

“an abnormal smallness of the auricle”
Atresia
“the absence of
an opening of
the external
canal”
Outer Ear Disorders


Microtia and atresia



Impacted cerumen



Perforation of the tympanic membrane
Perforation of the TM

n

An example of the audiogram illustrating the flat,
mild, conductive hearing loss that can occur with a
perforated tympanic membrane
Outer Ear Disorders


Microtia and atresia



Impacted cerumen



Perforation of the tympanic membrane



Other
Middle Ear Disorders


Otitis Media







Most common cause
of transient
conductive hearing
loss in children
Inflamation of the
middle ear
Caused by
eustachian tube
failure
Otitis Media
n

Three examples of
the usual
characteristics of a
conductive hearing
loss arising from
otitis media
Ways to Classify Otitis Media



With or without effusion
Fluid type




Serous
Suppurative
Mucoid
Ways to Classify Otitis Media
 With or without effusion
 Fluid type
 Duration
 Acute
 Chronic
 Subacute
 Persistent
 Recurrent
Otitis Media Facts








76-95% of all kids will have one episode of OM by
age 6
Prevalence is highest during the first two years of life
50% of all kids with one episode before their first
birthday will have 6 or more bouts within two years
Most episodes occur in winter and spring
Risk factors







Cleft palate
Down syndrome
Native Americans
Urban poor
Day care
Secondhand smoke
Middle Ear Disorders



Otitis media
Otosclerosis
Otosclerosis
“a bone disorder that affects the stapes
and the bony labyrinth of the inner ear.
The disease process is characterized
by resorption of bone and new spongy
formation around the stapes and oval
window”
Otosclerosis


Facts:

 Hereditary
 Women are more likely

to develop the disorder

 Usually bilateral
 progressive
Middle Ear Disorders




Otitis media
Otosclerosis
Cholesteatoma
Cholesteatoma
“an epithelial pocket that forms on the
tympanic membrane. Once the pocket
forms, the normal shedding of
epithelium results in growth of the
tumor”
Middle Ear Disorders





Otitis media
Otosclerosis
Cholesteatoma
Other


Physical trauma
Physical Trauma of the Middle
Ear
Here’s an example of
an audiogram
resulting from
disarticulation of the
ossicular chain
Middle Ear Disorders





Otitis media
Otosclerosis
Cholesteatoma
Other




Physical trauma
Barotrauma
Middle ear tumors


Glomus tumor
Cochlear Disorders


Syndromes and inherited disorders



Syndromic disorders
Nonsyndromal disorders
Syndromes and Inherited Disorders Resulting in
Sensorineural Hearing Loss
Types of Nonsyndromic
Disorders






Dominant
Dominant progressive
Dominant progressive with adult onset
Recessive hereditary SNHL
X-linked
Cochlear Disorders



Syndromes and inherited disorders
Noise induced hearing loss
Noise Induced Hearing Loss
The degree of SNHL depends on


The intensity of the noise



The spectral composition of the noise



The duration of exposure



Individual susceptibility
OSHA Damage Risk Criteria
Noise Induced SNHL





Noise notch
Cummulative
Progressive
Cochlear Disorders





Syndromes and inherited disorders
Noise induced hearing loss
Other trauma
Infections
Infections


Congenital


Cytomegalovirus



HIV



Rubella



Syphilis



Toxoplasmosis
Infections


Acquired


Herpes Zooster Oticus (Chicken Pox)



Mumps



Syphilis
Cochlear Disorders






Syndromes and inherited disorders
Noise induced hearing loss
Other trauma
Infections
Ototoxicity
Ototoxicity
 Some antibiotics that are often ototoxic:


Amikacin



Dihydrostreptomycin



Garamycin



Gentamicin



Kanamycin



Neomycin



Netilmicin



Streptomycin



Tobramycin



Viomycin
Ototoxicity


Chemotherapy
 Carboplatin
 Cisplatin



Drugs that cause reversible hearing loss
 Quinine
 Salicylates (aspirin)
 Loop diuretics



Drugs that may be harmful during pregnancy
 Accutane
 Dilantin
 Quinine
 Thalidomide
Cochlear Disorders







Syndromes and inherited disorders
Noise induced hearing loss
Other trauma
Infections
Ototoxicity
Meniere’s Disease
Meniere’s Disease


Symptoms




Tinnitus
Vertigo
Unilateral
sensorineural
hearing loss
Cochlear Disorders








Syndromes and inherited disorders
Noise induced hearing loss
Other trauma
Infections
Ototoxicity
Meniere’s Disease
Presbycusis
Presbycusis
Central Auditory Disorders




VIII Nerve tumors
Other diseases of the VIII Nerve
Neural disorders





Brain Stem disorders






Cochlear neuritis
Diabetes mellitus
Infarcts
Gliomas
Multiple sclerosis

Temporal Lobe disorders
Topic2

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Topic2

Editor's Notes

  1. OUTER AND MIDDLE EAR DISORDERS These pathologies are commonly of two types -structural defects due to embryologic malformations -structural changes secondary to infection or trauma
  2. •microtia and atresia--these are the most common congenital malformations of the auricle (pinna) and the external canal.
  3. •Impacted Cerumen--very common cause of temporary conductive HL. Very treatable and preventable. HL that results is flat, conductive, and of varying degree.
  4. •Perforation of the tympanic membrane--These usually occur either by trauma or secondary to OM.
  5. •Other disorders of the outer ear---there are others, but not common and usually don’t affect hearing unless the auditory meatus is blocked
  6. •Otitis Media--the most common cause of transient conductive HL in kids. OM is an inflammation of the middle ear. Caused by eustachian tube malfunction. When it is accompanied by middle ear effusion (fluid) it often causes a conductive HL.
  7. Ways to classify OM: -OM w/out effusion -fluid types: -duration:
  8. 76-95% of all kids will have one episode of OM by age 6. Prevalence is highest during the first 2 years, then declines after that. 50% of all kids with one episode before their first birthday will have 6 or more bouts within 2 years. Most episodes occur in winter and spring. Some populations are more prone to OM--kids with cleft palate or other craniofacial anomalies, Down syndrome, Native Americans, urban poor, day care kids, kids exposed to secondhand smoke.
  9. •Otosclerosis--a bone disorder that affects the stapes and the bony labyrinth of the inner ear. The disease process is characterized by resorption of bone and new spongy formation around the stapes and oval window.
  10. •Cholesteatoma--usually a secondary condition to OM. A cholesteatoma is an epithelial pocket that forms on the tympanic membrane. Once the pocket forms, the normal shedding of epithelium results in growth of the cholesteatoma, or tumor, which is capable of reabsorbing adjacent bone
  11. •Other middle ear disorders -physical trauma -barotrauma -Middle ear tumors
  12. •Syndromes and inherited Disorders -syndromic disorders: occurring as part of a constellation of other medical and physical disorders that occur together. -nonsyndromic disorders: autosomal recessive or dominant genetic conditions in which there is no other significant feature besides HL
  13. •Noise induced HL---very common cause of SNHL in adults. Right up there with presbycusis. This can happen with a one-time exposure to a very loud sound or long-time exposure to constant, softer sounds.
  14. Effects of noise are cumulative. How damaging sounds are to the cochlear are dependent on -the intensity of the sound. -the spectral composition of the sound -duration of exposure -individual susceptibility
  15. •Other trauma--physical trauma that causes a fracture of the temporal bone and leakage of endolymph.
  16. •Infections--we discussed congenital infections most commonly associated with SNHL that included: -cytomegalovirus -HIV -rubella -syphilis -toxoplasmosis
  17. Acquired infections: can be caused by viral or bacterial infections--and by fungi Some common acquired viral infections that can cause HL -Herpes Zoster Oticus--caused by a virus that also causes chicken pox. -Mumps----HL is rare but can occur related to encephalitis. -syphilis--occurs in the secondary or tertiary stage of the disease.
  18. •Ototoxicity--certain drugs and chemicals are toxic to the cochlea
  19. •Meniere’s Disease--endolymphatic hydrops. Triad of symptoms includes tinnitus, vertigo, and SNHL.
  20. •Presbycusis--decline in thresholds due to aging. The leading contributor to HL in adults. Estimates are that 25-40% of those over 65 have this.
  21. CNS DISORDERS The nature of the HL that accompanies CANS disorders vary as a function of location of the lesion--more peripheral, more apparent. Disruption in speech perception also gets more subtle as the lesion becomes more central. •VIII N. Tumors •Other tumors, cysts, and aneurysms can affect the VIII nerve and the cerebellopontine angle. •Neural disorders: -cochlear neuritis-- -diabetes mellitus •Brain Stem Disorders--these include infarcts, gliomas (fast growing tumors), and multiple sclerosis. •Temporal-Lobe Disorder