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BONE MINERAL
DENSITOMETRY: ARTIFACTS
AND TECHNIQUES
Ramin Sadeghi
Mashhad University of Medical Sciences
Hip: femoral neck and total femur
Case 1
• A 52 y/o female patient, referred for BMD.
• What is the technical error in the hip BMD?
Case 1
• For total femur ROI, number of pixels below the lesser
trochanter should not be more than 10.
• The correct ROI can be found in the next image.
Case 2
• A 78 y/o female patient referred for BMD.
• What is the technical error of the scan.
Case 2
• The femoral neck ROI should not contain any bone from
other parts of the pelvis.
• Specifically, the ischium should be excluded if needed.
Case 3
• A young female patient referred for BMD by Norland
device.
• What is the technical error for femoral neck BMD of the
patient.
Case 3
• For Norland, placement of femoral neck ROI is different
from Lunar and Hologic.
• For Norland:
• The part of the neck with shortest diameter should be used.
• For Lunad and Hologic:
• The ROI should be anchored to the greater trochanter border
• Correct ROI is shown in the next slides (for the same
patient by Norland and Hologic devices.
Discussion
• Correct placement of femoral ROIs for Lunar, Hologic and
Norland devices as well as correct acquisition can be
found in the next figures
Hologic
Norland
Lunar
Case 4
• A 43 y/o female patient referred for BMD
• In case of any anatomical derangement of the left femoral
neck area, the right femur should be used.
Total femur
• What is called total femur on processed BMD of the hip.
• Total femur= Neck+Intertrochantric+Trochantric areas
Case 5
• What is the technical problem of the BMD in the next slide
• Internal rotation of the femur is of utmost importance
during acquisition.
• The lesser trochanter should not be seen or only has a
minimal protuberance.
Spine
Case 1
• A 57 y/o male patient referred for BMD.
• What is your opinion regarding the spine BMD
• In case of more than 1 unit difference between two
adjacent vertebrae, the vertebra with higher T-score
should be omitted.
• VFA should help elucidate the reason of the difference.
Case 1
• The patient had a fall from a two-story building and the
reason of T-score difference was spine fracture
• If the patient had no history of alcohol or smoking, no
history of fracture in the relatives and no evidence of
secondary osteoporosis, please calculate the risk of
fracture using Frax.
• Femoral neck BMD=0.610
• For history of fracture, the fracture should be
disproportionate to the trauma. Otherwise, fracture should
not be included in Frax.
Case 2
• A 66 y/o male patient referred for BMD.
• That is your opinion regarding the spine BMD.
• For spine BMD, at most two vertebrae can be omitted
from processing. If only one vertebra remains, bilateral hip
BMD should be reported.
Case 3
• What is your opinion regarding the next slide BMD
• High BMI is a major problem in BMD. Quantum dots are
the hallmarks of high BMI.
Case 4
• A patient with history of secondary hyperparathyroidism
due to chronic renal failure.
• What is your opinion regarding this patient.
• The most common causes of high BMD are degenerative
changes and osteophytes.
• However other causes of high BMD should also be
considered in proper clinical setting.
• The current case had typical renal osteodystrophy and
“Rugger Jersey” appearance of the spine.
• In this case, forearm BMD should also be taken.
Case 5
• A young female patient referred for BMD.
• What is your opinion regarding this BMD
• Metal artifacts are common in BMD.
• In this patient piercing of the belly button was the cause of
high BMD of L4
Case 6
• What is your opinion regarding the BMD of the next slide.
• A common error in spine BMD is counting the lumbar
spine up-down and using rib as landmark. In 7% of
patients T12 does not have any visible rib and can cause
error.
• Shape of L5 (like an I on its side), and L4 (like an X) are
different from the other lumbar vertebrae.
• L3 usually has the largest transvers process.
• BMD has increasing trend from L1 to L3 and decreases
from L3 to L4 (usually).
• A combination of all above-criteria should be used for
delineation of L1 to L4.
Case 6 another example
Case 7
• What is your opinion regarding the BMD of this patient
• Oral contrast agents can remain in the GI system for
days.
• The patient should wait at least a week before trying BMD
Case 8
• A 68 y/o male patient referred for BMD.
• The patient had no history of fracture, no underlying
disease, smoking or alcohol consumption.
• Please calculate the fracture risk using Frax.
• For fracture risk assessment using Frax, history of
fracture should be considered positive if on VFA the
patient has typical spine fracture (even without history)
Similar case as case 8
Case 9
• What is your opinion regarding the BMD of the spine in
the next slide?
• Aortic calcification can be seen on VFA but usually can
not change BMD and there is no need for omitting
vertebrae.
Case 10
• Is the processing of BMD of the next slide correct?
• Lumbar sib is rare but can be misleading.
• The criteria of delineation of vertebrae should be followed.
Case 11
• What is the technical error in the BMD of the next slide
• Some technical errors are very subtle.
• In this case incomplete raising of the legs resulted in
incomplete flattening of the lumbar arc.
Forearm
Case 1
• A patient with primary hyperparathyroidism.
• What is your opinion regarding the BMD of this patient
• Processing of forearm BMD is very sensitive and operator
dependent. Different devices have different definitions for
forearm BMD.
• The part which is used for BMD is part of the radius which
corresponds to 1/3 length of ulna (next slide)
• Correct ROI of the patient can be found in the next slide
• Forearm processing and nomenculture of different
vendors can be found in the next slides
Case 2
• A 47 y/o female patient with history of primary
hyperparathyroidism
• What is your opinion regarding the forearm BMD of the
patient
• In patient with history of coles fracture, the non-dominant
forearm should be used for BMD
Case 3
• A 73 y/o left handed female patient with history of primary
hyperparathyrodism.
• What is your opinion on the patient’s BMD
• The non-dominant forearm should not be used for BMD
Bone mineral densitometry

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Bone mineral densitometry

  • 1. BONE MINERAL DENSITOMETRY: ARTIFACTS AND TECHNIQUES Ramin Sadeghi Mashhad University of Medical Sciences
  • 2. Hip: femoral neck and total femur
  • 3. Case 1 • A 52 y/o female patient, referred for BMD. • What is the technical error in the hip BMD?
  • 4.
  • 5. Case 1 • For total femur ROI, number of pixels below the lesser trochanter should not be more than 10. • The correct ROI can be found in the next image.
  • 6.
  • 7. Case 2 • A 78 y/o female patient referred for BMD. • What is the technical error of the scan.
  • 8.
  • 9. Case 2 • The femoral neck ROI should not contain any bone from other parts of the pelvis. • Specifically, the ischium should be excluded if needed.
  • 10.
  • 11. Case 3 • A young female patient referred for BMD by Norland device. • What is the technical error for femoral neck BMD of the patient.
  • 12.
  • 13. Case 3 • For Norland, placement of femoral neck ROI is different from Lunar and Hologic. • For Norland: • The part of the neck with shortest diameter should be used. • For Lunad and Hologic: • The ROI should be anchored to the greater trochanter border • Correct ROI is shown in the next slides (for the same patient by Norland and Hologic devices.
  • 14.
  • 15.
  • 16. Discussion • Correct placement of femoral ROIs for Lunar, Hologic and Norland devices as well as correct acquisition can be found in the next figures
  • 17.
  • 20. Lunar
  • 21. Case 4 • A 43 y/o female patient referred for BMD
  • 22.
  • 23.
  • 24. • In case of any anatomical derangement of the left femoral neck area, the right femur should be used.
  • 25.
  • 26. Total femur • What is called total femur on processed BMD of the hip.
  • 27.
  • 28. • Total femur= Neck+Intertrochantric+Trochantric areas
  • 29. Case 5 • What is the technical problem of the BMD in the next slide
  • 30.
  • 31. • Internal rotation of the femur is of utmost importance during acquisition. • The lesser trochanter should not be seen or only has a minimal protuberance.
  • 32.
  • 33. Spine
  • 34. Case 1 • A 57 y/o male patient referred for BMD. • What is your opinion regarding the spine BMD
  • 35.
  • 36. • In case of more than 1 unit difference between two adjacent vertebrae, the vertebra with higher T-score should be omitted. • VFA should help elucidate the reason of the difference.
  • 37.
  • 38.
  • 39. Case 1 • The patient had a fall from a two-story building and the reason of T-score difference was spine fracture • If the patient had no history of alcohol or smoking, no history of fracture in the relatives and no evidence of secondary osteoporosis, please calculate the risk of fracture using Frax. • Femoral neck BMD=0.610
  • 40. • For history of fracture, the fracture should be disproportionate to the trauma. Otherwise, fracture should not be included in Frax.
  • 41.
  • 42. Case 2 • A 66 y/o male patient referred for BMD. • That is your opinion regarding the spine BMD.
  • 43.
  • 44. • For spine BMD, at most two vertebrae can be omitted from processing. If only one vertebra remains, bilateral hip BMD should be reported.
  • 45.
  • 46.
  • 47. Case 3 • What is your opinion regarding the next slide BMD
  • 48.
  • 49. • High BMI is a major problem in BMD. Quantum dots are the hallmarks of high BMI.
  • 50. Case 4 • A patient with history of secondary hyperparathyroidism due to chronic renal failure. • What is your opinion regarding this patient.
  • 51.
  • 52.
  • 53. • The most common causes of high BMD are degenerative changes and osteophytes. • However other causes of high BMD should also be considered in proper clinical setting. • The current case had typical renal osteodystrophy and “Rugger Jersey” appearance of the spine. • In this case, forearm BMD should also be taken.
  • 54.
  • 55. Case 5 • A young female patient referred for BMD. • What is your opinion regarding this BMD
  • 56.
  • 57. • Metal artifacts are common in BMD. • In this patient piercing of the belly button was the cause of high BMD of L4
  • 58.
  • 59. Case 6 • What is your opinion regarding the BMD of the next slide.
  • 60.
  • 61. • A common error in spine BMD is counting the lumbar spine up-down and using rib as landmark. In 7% of patients T12 does not have any visible rib and can cause error. • Shape of L5 (like an I on its side), and L4 (like an X) are different from the other lumbar vertebrae. • L3 usually has the largest transvers process. • BMD has increasing trend from L1 to L3 and decreases from L3 to L4 (usually). • A combination of all above-criteria should be used for delineation of L1 to L4.
  • 62.
  • 63.
  • 64.
  • 65.
  • 66. Case 6 another example
  • 67.
  • 68.
  • 69. Case 7 • What is your opinion regarding the BMD of this patient
  • 70.
  • 71. • Oral contrast agents can remain in the GI system for days. • The patient should wait at least a week before trying BMD
  • 72. Case 8 • A 68 y/o male patient referred for BMD. • The patient had no history of fracture, no underlying disease, smoking or alcohol consumption. • Please calculate the fracture risk using Frax.
  • 73.
  • 74.
  • 75.
  • 76. • For fracture risk assessment using Frax, history of fracture should be considered positive if on VFA the patient has typical spine fracture (even without history)
  • 77. Similar case as case 8
  • 78.
  • 79.
  • 80. Case 9 • What is your opinion regarding the BMD of the spine in the next slide?
  • 81.
  • 82.
  • 83. • Aortic calcification can be seen on VFA but usually can not change BMD and there is no need for omitting vertebrae.
  • 84. Case 10 • Is the processing of BMD of the next slide correct?
  • 85.
  • 86. • Lumbar sib is rare but can be misleading. • The criteria of delineation of vertebrae should be followed.
  • 87. Case 11 • What is the technical error in the BMD of the next slide
  • 88.
  • 89. • Some technical errors are very subtle. • In this case incomplete raising of the legs resulted in incomplete flattening of the lumbar arc.
  • 90.
  • 91.
  • 93. Case 1 • A patient with primary hyperparathyroidism. • What is your opinion regarding the BMD of this patient
  • 94.
  • 95.
  • 96.
  • 97. • Processing of forearm BMD is very sensitive and operator dependent. Different devices have different definitions for forearm BMD. • The part which is used for BMD is part of the radius which corresponds to 1/3 length of ulna (next slide)
  • 98.
  • 99. • Correct ROI of the patient can be found in the next slide
  • 100.
  • 101. • Forearm processing and nomenculture of different vendors can be found in the next slides
  • 102.
  • 103.
  • 104.
  • 105. Case 2 • A 47 y/o female patient with history of primary hyperparathyroidism • What is your opinion regarding the forearm BMD of the patient
  • 106.
  • 107. • In patient with history of coles fracture, the non-dominant forearm should be used for BMD
  • 108.
  • 109. Case 3 • A 73 y/o left handed female patient with history of primary hyperparathyrodism. • What is your opinion on the patient’s BMD
  • 110.
  • 111. • The non-dominant forearm should not be used for BMD