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PHARMACOTHERAPEUTICS - II
CASE PRESENTATION ON
SQUAMOUS CELL CARCINOMA OF
RIGHT LUNG
III/VI PHARM-D
SOAP note
A male patient of age 51 years was admitted in the hospital with
Following information;
SUBJECTIVE DATA:
Chief complaints: difficulty in breathing, extreme fatigue
Past medication history:Duolin rotacaps, Maxiflo rotacaps since 3yrs
Allergies: nill
Family history:Father died of heart attack
PERSONAL HISTORY AND HABITS
Height: - Weight: - BMI: -
Education: NA Occupation: Carpenter
Diet(non-veg/veg): Mixed Alcoholic/Smoker: yes
Sleep: Normal Appetite: Fair
Bowel & Bladder habits: Normal
OBJECTIVE DATA
Physical examination :
PARAMETE
R
D1 D2 D3
Temp(*F) 98 99 98
PR(beats/min) 72 70 72
BP(cycles/mm) 120/80 120/80 120/8o
RR(Cycles/min 20 22 20
SYSTEMATIC EXAMINATION:
 RS: - difficulty in breathing
 CNS: -
 CVS: -
 GU&GI: -
 ENT: -
 Dermatologists(skin): -
 Extremities(UL&LL):
DIAGNOSTIC TESTS:
Histopathology report: Squamous cell carcinoma of right lung
PARAMETERS NORMAL VALUE PATIENT
VALUE
HB M 12-15.5 gm/dl 9.4
PCV M 45-52% 27
PLATELET
COUNT
1.5-4.5lakhs/mm 2.8
TOTAL RBC M-4.7-6.1millions/mm 3.3
TOTAL WBC 4000-11000cells/mm 9,100
NEUTROPHILLS 45-75% 43
LABORATORY INVESTIGATIONS:
PARAMETERS NORMAL VALUE PATIENT VALUE
LYPHOCYTES 20-40% 48
MONOCYTES 1-10% 7
EOSINOPHILLS <7% 2
BASOPHILLS 0-1% 0
BUN 7-20mg/dl 35
SERUM CREATININE M 0.6-1.2mg/dl 1.2
ASSESSMENT
CONFIRMATORY DIAGNOSIS:
Squamous cell carcinoma of right lung
WHAT IS CANCER?
Cancer is a disease characterised by uncontrollable , irreversible, independent,
uncoordinated & relatively unlimited& abnormal overgrowth of tissues.
caused by: tobacco smoking, occupational exposure of toxins, other medical
conditions, mutations or can be idiopathic
S.N
O
BRAND NAME GENERIC
NAME
DOSE ROA FREQ D-1 D-2 D-3
1 INJ.ZOFER+
DECADRAN
ondansetron+
dexamethasone
8+6mg
in
100ml
NS
IV OD
+ + +
2 INJ.RANTAC ranitidine 50mg/
2ml
IV OD
+ + +
3 INJ.AVIL pheniramine 2ml IV OD
+ + +
4 INJ.CISPLATIN cisplatin 50mg IV OD
+ + +
PHARMACOLOGICAL THERAPY:
S.
N
O
BRAND
NAME
GENERIC
NAME
DOSE ROA FREQ D-1 D-2 D-3
5 INJ.ETOPOSIDE etoposide 150mg IV OD + + +
6 INJ.DECADRON dexamethasone 16mg IV OD + + +
7 INJ.ZOFER ondansetron 8mg IV OD + + +
8 INJ.LASIX furosemide 20 gm IV OD + + +
NOTE: The same above given chemotherapy regimen is repeated for 5
times
DISCHARGE MEDICATIONS:
Duolin rotacaps can be continued.
NON PHARMACOLOGICAL THERAPY:
PATIENT COUNSELLING :
1.Regarding disease:
 The main etiology for development of cancer is smoking.
 Patient is educated about further complications of the condition and regarding the signs &
symptoms
2.Regarding medication:
 The patient is advised to take medications regularly.
3.Regarding life style modifications:
 The patient is suggested to Drink plenty of water to remove the waste materials
from the body & to eat healthy
 The patient is advised to change his exposure to dust via his occupation
 The patient is also cautioned to quit smoking.
DRUG INTRACTIONS:
cisplatin X etoposide [MODERATE] : nausea & vomiting are avoided by
ondansetron
furosemide X dexamethasone [MODERATE] : by adjusting the doses of above
drugs ,the interactions can be overcomed.
Squamous cell carcinoma of right lung

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Squamous cell carcinoma of right lung

  • 1. PHARMACOTHERAPEUTICS - II CASE PRESENTATION ON SQUAMOUS CELL CARCINOMA OF RIGHT LUNG III/VI PHARM-D
  • 2. SOAP note A male patient of age 51 years was admitted in the hospital with Following information; SUBJECTIVE DATA: Chief complaints: difficulty in breathing, extreme fatigue Past medication history:Duolin rotacaps, Maxiflo rotacaps since 3yrs Allergies: nill Family history:Father died of heart attack
  • 3. PERSONAL HISTORY AND HABITS Height: - Weight: - BMI: - Education: NA Occupation: Carpenter Diet(non-veg/veg): Mixed Alcoholic/Smoker: yes Sleep: Normal Appetite: Fair Bowel & Bladder habits: Normal
  • 4. OBJECTIVE DATA Physical examination : PARAMETE R D1 D2 D3 Temp(*F) 98 99 98 PR(beats/min) 72 70 72 BP(cycles/mm) 120/80 120/80 120/8o RR(Cycles/min 20 22 20
  • 5. SYSTEMATIC EXAMINATION:  RS: - difficulty in breathing  CNS: -  CVS: -  GU&GI: -  ENT: -  Dermatologists(skin): -  Extremities(UL&LL): DIAGNOSTIC TESTS: Histopathology report: Squamous cell carcinoma of right lung
  • 6. PARAMETERS NORMAL VALUE PATIENT VALUE HB M 12-15.5 gm/dl 9.4 PCV M 45-52% 27 PLATELET COUNT 1.5-4.5lakhs/mm 2.8 TOTAL RBC M-4.7-6.1millions/mm 3.3 TOTAL WBC 4000-11000cells/mm 9,100 NEUTROPHILLS 45-75% 43 LABORATORY INVESTIGATIONS:
  • 7. PARAMETERS NORMAL VALUE PATIENT VALUE LYPHOCYTES 20-40% 48 MONOCYTES 1-10% 7 EOSINOPHILLS <7% 2 BASOPHILLS 0-1% 0 BUN 7-20mg/dl 35 SERUM CREATININE M 0.6-1.2mg/dl 1.2
  • 8. ASSESSMENT CONFIRMATORY DIAGNOSIS: Squamous cell carcinoma of right lung WHAT IS CANCER? Cancer is a disease characterised by uncontrollable , irreversible, independent, uncoordinated & relatively unlimited& abnormal overgrowth of tissues. caused by: tobacco smoking, occupational exposure of toxins, other medical conditions, mutations or can be idiopathic
  • 9.
  • 10. S.N O BRAND NAME GENERIC NAME DOSE ROA FREQ D-1 D-2 D-3 1 INJ.ZOFER+ DECADRAN ondansetron+ dexamethasone 8+6mg in 100ml NS IV OD + + + 2 INJ.RANTAC ranitidine 50mg/ 2ml IV OD + + + 3 INJ.AVIL pheniramine 2ml IV OD + + + 4 INJ.CISPLATIN cisplatin 50mg IV OD + + + PHARMACOLOGICAL THERAPY:
  • 11. S. N O BRAND NAME GENERIC NAME DOSE ROA FREQ D-1 D-2 D-3 5 INJ.ETOPOSIDE etoposide 150mg IV OD + + + 6 INJ.DECADRON dexamethasone 16mg IV OD + + + 7 INJ.ZOFER ondansetron 8mg IV OD + + + 8 INJ.LASIX furosemide 20 gm IV OD + + + NOTE: The same above given chemotherapy regimen is repeated for 5 times
  • 12. DISCHARGE MEDICATIONS: Duolin rotacaps can be continued. NON PHARMACOLOGICAL THERAPY: PATIENT COUNSELLING : 1.Regarding disease:  The main etiology for development of cancer is smoking.  Patient is educated about further complications of the condition and regarding the signs & symptoms
  • 13. 2.Regarding medication:  The patient is advised to take medications regularly. 3.Regarding life style modifications:  The patient is suggested to Drink plenty of water to remove the waste materials from the body & to eat healthy  The patient is advised to change his exposure to dust via his occupation  The patient is also cautioned to quit smoking.
  • 14. DRUG INTRACTIONS: cisplatin X etoposide [MODERATE] : nausea & vomiting are avoided by ondansetron furosemide X dexamethasone [MODERATE] : by adjusting the doses of above drugs ,the interactions can be overcomed.