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CASE PRESENTATION ONCASE PRESENTATION ON
SEPSIS WITH PERITONITISSEPSIS WITH PERITONITIS
BY
D.HIMAJA
14Z91T0004
PATIENT DEMOGRAPHIC DETAILSPATIENT DEMOGRAPHIC DETAILS
Name - Sarayu
Age - 2 years
Gender - female
Weight - 10kgs
Height - 76 cms
Ip number - 18003691
Department -paediatrics
Date of admission – 12 /12/18
Date of discharge - 22/12/18
SOAP ANALYSISSOAP ANALYSIS
SUBJECTIVE EVIDENCESUBJECTIVE EVIDENCE
c/o-vomiting,seizures, loose stools since
7 days.
Past medical history:-right sided VP
shunt with ependymoma.
Past surgical history:- operted for
tethered cord syndrome. Pateint
developed status epilepticus associated
with fever.
On examination:-On examination:-
Child is sleeping , afebrile
Abdomen –soft
CNS tone-normal on painful stimuli
CVS - s₁s₂ heard
Breath sounds-clear
Lungs – bilateral air entry.
VITALS:-VITALS:-
Pulse rate-86/min
Respiratory rate-24/min
Spo₂ - 99%
Temperature – 98.7°F
Preliminary diagnosis:- hydrocephalus
with bilateral VP shunt ? Peritonitis.
OBJECTIVEOBJECTIVE
EVIDENCEEVIDENCE
CT brain- hydrocephalus .
USG- Gall bladder –well distended
urinary bladder-empty with folings bulb.
Uterus-Mild IU free fluid with multiple thin
echogenic septation.
MRI- infected epidermoid cyst-dorsal
dermal sinus extending spinal cord at
s₂₋₃lever. Extensive lepto meningitis
ASSESSMENTASSESSMENT
From the subjective and objective
findings the child is diagnosed with
sepsis with peritonitis and spastic
paraparesis.
DRUG CHARTDRUG CHART
DRUG NAME GENERIC
NAME
DOSE ROUT
E
FREQU
ENCY
1 2 3 4 5 6 7 8 9 10
Isolyte Iv fluids 700ml IV OD + + + + + - - - - --
Taxim Cefixime 250mg IV BD + + + + + + + + + +
Amikacin Amikacin 25mg IV BD + + + + + + + + + +
Levipil Levitriacet
am
20 mg IV BD + + + + + + + + + +
Encorate Sod.
valproate
20 ml IV BD + + + + + + + + + +
Mannitol Mannitol 20ml IV TID + + + + + + + + + +
Lorazepam Lorzepam 10mg IV BD - - - + + + + + + +
Phenytoin Phenytoin 20 mg IV OD - - - - - - + + + +
Cefotaxim Cefotaxim 1 gm IV BD + + + + + - - + + +
DRUG NAME GENERIC
NAME
DOSE ROUT
E
FREQU
ENCY
1 2 3 4 5 6 7 8 9 10
Rantac Ranitidine 150mg IV BD - - + + + + + + + +
Ceftriaxone Ceftriaxone 350mg IV BD + + + + + - - - - -
Zofer Ondansetron 2mg IV BD - + + + + + + + + +
Lorazepam Lorazepam 0.7mg IV SOS - - - + + + + + + +
Paracetamol Paracetamol 4 ml oral SOS + + + + + + + + + +
Metrogyl Metronidazol
e
50 mg IV TID - - - - - + + + + +
Meropenem Meropenem 10mg IV BD + + + + + + + + + +
targocid Teicoplanin 70mg IV OD + + + + + + + + + +
PHARMACIST INTERVENTIONPHARMACIST INTERVENTION
Therapeutic duplication found I this
prescription :-
Lorazepam a benzodiazepine derivative
drug has been given to the patient in two
different doses i.e, (1mg and 0.7 mg)
DRUG INTERACTIONSDRUG INTERACTIONS
 Three major drug- drug interactions were found
in this prescription.
Valproic acid + meropenem
Meropenem decreases levels of valproic acid
by unknown mechanism. Avoid or Use Alternate
Drug. Risk of seizure. Possible decreased GI
absorption and/or increased renal clearance of
valproic acid
Amikacin + mannitol
 Co administration of parenteral or inhaled
aminoglycoside antibiotics or oral neomycin in
combination with loop diuretics may potentiate the risk
of oto- or nephrotoxicity due to additive or synergistic
pharmacologic effects of these drugs and or altered
aminoglycoside serum and tissue levels
Amikacin + Teicoplanin
Amikacin and teicoplanin both increase nephrotoxicity
and/or oto toxicity. Avoid or Use Alternate Drug
DISCHARGE MEDICATIONSDISCHARGE MEDICATIONS
Syp. Paracetamol 4ml oral sos - 15 days
Inj.rantac 50 mg iv od - 15 days
Tab metrogyl 50 mg oral od - 15 days
Tab ceftriaxone 350mg oral od - 15 days
Tab ondansetron 2 mg oral od - 15 days
Tab phenytoin 10 mg oral od - 15 days
 Review after 15 days in op department
PATIENT COUNSELLINGPATIENT COUNSELLING
 Ketogenic diet consisting of relatively low
carbohydrate and adequate protein with high
fats content is to be recommended under the
supervision of dietician .
 Encourage the child to sleep well and take
medications on time .
 Care during seizures allow the saliva secretions
to drain or vomit and do not stop child
movements or convulsions.
 If seizures lasts longer than 5 min seek
immediate treatment.

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Case presentation on sepsis with peritonitis

  • 1. CASE PRESENTATION ONCASE PRESENTATION ON SEPSIS WITH PERITONITISSEPSIS WITH PERITONITIS BY D.HIMAJA 14Z91T0004
  • 2. PATIENT DEMOGRAPHIC DETAILSPATIENT DEMOGRAPHIC DETAILS Name - Sarayu Age - 2 years Gender - female Weight - 10kgs Height - 76 cms Ip number - 18003691 Department -paediatrics Date of admission – 12 /12/18 Date of discharge - 22/12/18
  • 4. SUBJECTIVE EVIDENCESUBJECTIVE EVIDENCE c/o-vomiting,seizures, loose stools since 7 days. Past medical history:-right sided VP shunt with ependymoma. Past surgical history:- operted for tethered cord syndrome. Pateint developed status epilepticus associated with fever.
  • 5. On examination:-On examination:- Child is sleeping , afebrile Abdomen –soft CNS tone-normal on painful stimuli CVS - s₁s₂ heard Breath sounds-clear Lungs – bilateral air entry.
  • 6. VITALS:-VITALS:- Pulse rate-86/min Respiratory rate-24/min Spo₂ - 99% Temperature – 98.7°F Preliminary diagnosis:- hydrocephalus with bilateral VP shunt ? Peritonitis.
  • 8. CT brain- hydrocephalus . USG- Gall bladder –well distended urinary bladder-empty with folings bulb. Uterus-Mild IU free fluid with multiple thin echogenic septation. MRI- infected epidermoid cyst-dorsal dermal sinus extending spinal cord at s₂₋₃lever. Extensive lepto meningitis
  • 9. ASSESSMENTASSESSMENT From the subjective and objective findings the child is diagnosed with sepsis with peritonitis and spastic paraparesis.
  • 10. DRUG CHARTDRUG CHART DRUG NAME GENERIC NAME DOSE ROUT E FREQU ENCY 1 2 3 4 5 6 7 8 9 10 Isolyte Iv fluids 700ml IV OD + + + + + - - - - -- Taxim Cefixime 250mg IV BD + + + + + + + + + + Amikacin Amikacin 25mg IV BD + + + + + + + + + + Levipil Levitriacet am 20 mg IV BD + + + + + + + + + + Encorate Sod. valproate 20 ml IV BD + + + + + + + + + + Mannitol Mannitol 20ml IV TID + + + + + + + + + + Lorazepam Lorzepam 10mg IV BD - - - + + + + + + + Phenytoin Phenytoin 20 mg IV OD - - - - - - + + + + Cefotaxim Cefotaxim 1 gm IV BD + + + + + - - + + +
  • 11. DRUG NAME GENERIC NAME DOSE ROUT E FREQU ENCY 1 2 3 4 5 6 7 8 9 10 Rantac Ranitidine 150mg IV BD - - + + + + + + + + Ceftriaxone Ceftriaxone 350mg IV BD + + + + + - - - - - Zofer Ondansetron 2mg IV BD - + + + + + + + + + Lorazepam Lorazepam 0.7mg IV SOS - - - + + + + + + + Paracetamol Paracetamol 4 ml oral SOS + + + + + + + + + + Metrogyl Metronidazol e 50 mg IV TID - - - - - + + + + + Meropenem Meropenem 10mg IV BD + + + + + + + + + + targocid Teicoplanin 70mg IV OD + + + + + + + + + +
  • 12. PHARMACIST INTERVENTIONPHARMACIST INTERVENTION Therapeutic duplication found I this prescription :- Lorazepam a benzodiazepine derivative drug has been given to the patient in two different doses i.e, (1mg and 0.7 mg)
  • 13. DRUG INTERACTIONSDRUG INTERACTIONS  Three major drug- drug interactions were found in this prescription. Valproic acid + meropenem Meropenem decreases levels of valproic acid by unknown mechanism. Avoid or Use Alternate Drug. Risk of seizure. Possible decreased GI absorption and/or increased renal clearance of valproic acid
  • 14. Amikacin + mannitol  Co administration of parenteral or inhaled aminoglycoside antibiotics or oral neomycin in combination with loop diuretics may potentiate the risk of oto- or nephrotoxicity due to additive or synergistic pharmacologic effects of these drugs and or altered aminoglycoside serum and tissue levels Amikacin + Teicoplanin Amikacin and teicoplanin both increase nephrotoxicity and/or oto toxicity. Avoid or Use Alternate Drug
  • 15. DISCHARGE MEDICATIONSDISCHARGE MEDICATIONS Syp. Paracetamol 4ml oral sos - 15 days Inj.rantac 50 mg iv od - 15 days Tab metrogyl 50 mg oral od - 15 days Tab ceftriaxone 350mg oral od - 15 days Tab ondansetron 2 mg oral od - 15 days Tab phenytoin 10 mg oral od - 15 days  Review after 15 days in op department
  • 16. PATIENT COUNSELLINGPATIENT COUNSELLING  Ketogenic diet consisting of relatively low carbohydrate and adequate protein with high fats content is to be recommended under the supervision of dietician .  Encourage the child to sleep well and take medications on time .  Care during seizures allow the saliva secretions to drain or vomit and do not stop child movements or convulsions.  If seizures lasts longer than 5 min seek immediate treatment.