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Presentation on prostate
hyperplasia in dog
Presented by
Md. Rakibul Hasan Rakib
ID No. 1401097
Reg No. 41242
Talk Plan
 Introduction
 Etiology
 Pathophysiology
 Symptoms
 Differential diagnosis
 Diagnosis
 Treatment
 Living & Management
Prostate Hyperplasia (PH)
 PH is the most common condition seen in
dogs. It is a non-malignant increase in the size
of the prostate gland related directly to the
influence of the hormone testosterone.
Etiology
Hormonal imbalances
Age
Age Percentage %
5 50
6 60
9 95
Pathophysiology
• Hyperplastic process
• Earliest sign : micro-nodule formation in
transitional zone – lateral lobes (mixture of
stromal cell and epithelial component ) and in
periurethral region – median lobe within the
smooth muscle collar of the preprosthatic
sphincter (mainly connective tissue)
• Further coalescence and growth of
micronodule become macronodule
Symptoms
• Bloody discharge from
urethra
• Blood in urine
• Urinating frequently
• Blood in ejaculate
• Difficulty in urination
• Difficulty with defecation
• Ribbon like stools
A
B
C
Differential Diagnosis
• Prostatic neoplasia
• Cysts
PH Vs Prostatic Neoplasia
PH Prostatic neoplasia
Most common prostatic disorders Rare
50-95% by 4-9 years of age 0.2-0.6% in dog
Androgen dependent Non-Androgenic
Benign malignant
No tumor present Tumor has necrotic center
Only intact male dogs Neutered and intact male dogs
Diagnosis
 A rectal exam will confirm the presence of an
enlarged prostate gland.
 Blood work, urinalysis, x-rays, an ultrasound,
a urine culture and microscopic evaluation of
fluid drawn from the prostate gland can help
confirm the diagnosis.
 In diagnosing BPH, it's important to rule out
other causes of an enlarged prostate,
including cysts, infection with inflammation
and cancer
Treatment
 Castration
 Synthetic Steroid drug such as Delmadione
acetate
 Antiandrogens including flutamide ,
finasteriod & formestane may reduce
the stimulation effect of testosterone
 Pumpkin seed , natural vitamin E
& selenium can all be beneficial in
regulating PH in dogs.
 Estrogen & Progesteron
Living and management
Prostate Hyperplasia is an age-related problem
and castration is the best method for avoiding or
treating this problem in dogs.
Any Question.…….?

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Prostate hyperplasia of Dog

  • 1. Presentation on prostate hyperplasia in dog Presented by Md. Rakibul Hasan Rakib ID No. 1401097 Reg No. 41242
  • 2. Talk Plan  Introduction  Etiology  Pathophysiology  Symptoms  Differential diagnosis  Diagnosis  Treatment  Living & Management
  • 3. Prostate Hyperplasia (PH)  PH is the most common condition seen in dogs. It is a non-malignant increase in the size of the prostate gland related directly to the influence of the hormone testosterone.
  • 5. Pathophysiology • Hyperplastic process • Earliest sign : micro-nodule formation in transitional zone – lateral lobes (mixture of stromal cell and epithelial component ) and in periurethral region – median lobe within the smooth muscle collar of the preprosthatic sphincter (mainly connective tissue) • Further coalescence and growth of micronodule become macronodule
  • 6. Symptoms • Bloody discharge from urethra • Blood in urine • Urinating frequently • Blood in ejaculate • Difficulty in urination • Difficulty with defecation • Ribbon like stools
  • 9. PH Vs Prostatic Neoplasia PH Prostatic neoplasia Most common prostatic disorders Rare 50-95% by 4-9 years of age 0.2-0.6% in dog Androgen dependent Non-Androgenic Benign malignant No tumor present Tumor has necrotic center Only intact male dogs Neutered and intact male dogs
  • 10. Diagnosis  A rectal exam will confirm the presence of an enlarged prostate gland.  Blood work, urinalysis, x-rays, an ultrasound, a urine culture and microscopic evaluation of fluid drawn from the prostate gland can help confirm the diagnosis.  In diagnosing BPH, it's important to rule out other causes of an enlarged prostate, including cysts, infection with inflammation and cancer
  • 11.
  • 12. Treatment  Castration  Synthetic Steroid drug such as Delmadione acetate  Antiandrogens including flutamide , finasteriod & formestane may reduce the stimulation effect of testosterone  Pumpkin seed , natural vitamin E & selenium can all be beneficial in regulating PH in dogs.  Estrogen & Progesteron
  • 13. Living and management Prostate Hyperplasia is an age-related problem and castration is the best method for avoiding or treating this problem in dogs.
  • 14.