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Edited by: Jessica Hawley
Compiled by: Hailey Haberman
Mendel’s Law of Inheritance
Genotypes, Phenotypes & Punnett
Square
Objectives:
 Explain Gregor Mendel’s laws of inheritance
 Discuss the difference between genotypes and
phenotypes
 Label the three types of genotypes
 Draw and label a Punnett square
 Predict outcomes of a Punnett square
Mendel
 Modern genetics had its beginnings in an abbey
garden, where a monk named Gregor Mendel
documented a particulate mechanism of
inheritance.
 He discovered the basic principles of heredity by
breeding garden peas in carefully planned
experiments.
 His approach to science had been influenced at the
University of Vienna by one of his professors: the
Mendel’s work
 In order to study inheritance, Mendel chose to
use peas, probably as they are available in many
varieties.
 The use of plants also allowed strict control over
the mating.
 He chose to study only characters that varied in
an ‘either-or’ rather than a ‘more-or-less’ manner.
Genetic crosses
 To cross two different pea
plants, Mendel used an
artist’s brush.
 He transferred pollen from
a true breeding white
flower to the carpel of a
true breeding purple
flower.
Tracking Characteristics
 Mendel tracked heritable
characters for 3 generations.
 When F1 hybrids were
allowed to self-pollinate a 3:1
ratio of the 2 varieties
occurred in the F2 generation.
Mendel’s terminology
 True breeding: When the plants self-pollinate, all
their offspring are of the same variety.
 Hybridization: Mating, or crossing, of two varieties.
 Monohybrid cross: A cross between two parents
that breed true for different versions of a single
trait.
Mendel’s terminology
 P generation: True breeding parents.
 F1 generation: (first filial) Hybrid offspring of the P
generation.
 F2 generation: (second filial) Offspring from the
self-fertilisation of the F1 hybrids.
What is Genetics?
 All body cells contain “Blueprints” with instructions
as to how an animal will look or act etc.
 One Gene comes from each parent (pairs)
 Genes are divided into sections (Chromosomes)
that carry genes
 Sex chromosomes: Male = XY, Female =
XX
Genotypes
 The genotype refers to the entire set of genes in a
cell, an organism, or an individual. A gene for a
particular character
or trait may exist in
two forms; one is
dominant (E) and the
other is recessive (e).
Dominant and Recessive Genes
 Dominant Genes
 One gene overshadows the other.
 Recessive Gene
 The gene that is overshadowed by a dominant
gene.
Examples of Genotypes
 There are three basic genotypes for a
particular
character:
 AA = homozygous dominant
 Aa = heterozygous
 aa = homozygous recessive
Phenotypes
 Phenotype is the physical
appearance or other
characteristic of an organism
as a result of the interaction of
its genotype and the
environment.
Some examples would be:
•Size
•Shape
•Color
The Punnett Square
 Is a square grid used in genetics to calculate the
frequencies of the different genotypes and
phenotypes among the offspring of a cross
Genotypes and
Phenotypes of Offspring's
Use a Punnett Square
A A
a
a
Punnett Square Example
Traits for color
A A
a Aa Aa
a Aa Aa
Punnett Square Example Cont..
 The male genotype is normally indicated at the
top and the female genotype is indicated in the
vertical margin.
 homozygous dominant parents (PP x PP), all
offspring will be homozygous dominant polled
individuals.
 When crossing homozygous recessive parents
(pp x pp), all of the offspring will be horned
(homozygous recessive) individuals.
 Crossing a heterozygous parent with a
homozygous dominant parent (Pp x PP), the
expected offspring would occur in a 1:1 ratio of
homozygous dominant to heterozygous
individuals.
 Phenotype:
 All offspring would be polled.
 We have a Angus Bull and a Charolais Cow.
 The Angus (black) is Homozygous Dominant
 The Charolais (white) is Homozygous Recessive
 How would you set up the Punnett Square?
Punnett Square Example
 When crossing a homozygous dominant parent
with a homozygous recessive parent (PP x pp),
all offspring would be heterozygous and polled.
 If two heterozygous parents are crossed (Pp x Pp),
one can expect a genotypic ratio of 1:2:1, with one
homozygous dominant polled, two heterozygous
polled, and one homozygous recessive horned
individuals.
 The expected phenotypic ratio of offspring would be
3:1 (polled to horned).
Lets Practice
 http://glencoe.mcgraw-
hill.com/sites/0078759864/student_view0/unit3/ch
apter10/virtual_labs.html#
Objectives
 Explain Gregor Mendel’s laws of inheritance
 Discuss the difference between genotypes and
phenotypes
 Label the three types of genotypes
 Draw and label a Punnett square
 Predict outcomes of a Punnett square

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MolecularGeneticsUnit4-6.pptx

  • 1. Edited by: Jessica Hawley Compiled by: Hailey Haberman Mendel’s Law of Inheritance Genotypes, Phenotypes & Punnett Square
  • 2. Objectives:  Explain Gregor Mendel’s laws of inheritance  Discuss the difference between genotypes and phenotypes  Label the three types of genotypes  Draw and label a Punnett square  Predict outcomes of a Punnett square
  • 3. Mendel  Modern genetics had its beginnings in an abbey garden, where a monk named Gregor Mendel documented a particulate mechanism of inheritance.  He discovered the basic principles of heredity by breeding garden peas in carefully planned experiments.  His approach to science had been influenced at the University of Vienna by one of his professors: the
  • 4. Mendel’s work  In order to study inheritance, Mendel chose to use peas, probably as they are available in many varieties.  The use of plants also allowed strict control over the mating.  He chose to study only characters that varied in an ‘either-or’ rather than a ‘more-or-less’ manner.
  • 5. Genetic crosses  To cross two different pea plants, Mendel used an artist’s brush.  He transferred pollen from a true breeding white flower to the carpel of a true breeding purple flower.
  • 6. Tracking Characteristics  Mendel tracked heritable characters for 3 generations.  When F1 hybrids were allowed to self-pollinate a 3:1 ratio of the 2 varieties occurred in the F2 generation.
  • 7. Mendel’s terminology  True breeding: When the plants self-pollinate, all their offspring are of the same variety.  Hybridization: Mating, or crossing, of two varieties.  Monohybrid cross: A cross between two parents that breed true for different versions of a single trait.
  • 8. Mendel’s terminology  P generation: True breeding parents.  F1 generation: (first filial) Hybrid offspring of the P generation.  F2 generation: (second filial) Offspring from the self-fertilisation of the F1 hybrids.
  • 9. What is Genetics?  All body cells contain “Blueprints” with instructions as to how an animal will look or act etc.  One Gene comes from each parent (pairs)  Genes are divided into sections (Chromosomes) that carry genes  Sex chromosomes: Male = XY, Female = XX
  • 10. Genotypes  The genotype refers to the entire set of genes in a cell, an organism, or an individual. A gene for a particular character or trait may exist in two forms; one is dominant (E) and the other is recessive (e).
  • 11. Dominant and Recessive Genes  Dominant Genes  One gene overshadows the other.  Recessive Gene  The gene that is overshadowed by a dominant gene.
  • 12. Examples of Genotypes  There are three basic genotypes for a particular character:  AA = homozygous dominant  Aa = heterozygous  aa = homozygous recessive
  • 13. Phenotypes  Phenotype is the physical appearance or other characteristic of an organism as a result of the interaction of its genotype and the environment. Some examples would be: •Size •Shape •Color
  • 14. The Punnett Square  Is a square grid used in genetics to calculate the frequencies of the different genotypes and phenotypes among the offspring of a cross
  • 15. Genotypes and Phenotypes of Offspring's Use a Punnett Square
  • 16. A A a a Punnett Square Example Traits for color
  • 17. A A a Aa Aa a Aa Aa Punnett Square Example Cont..
  • 18.  The male genotype is normally indicated at the top and the female genotype is indicated in the vertical margin.
  • 19.  homozygous dominant parents (PP x PP), all offspring will be homozygous dominant polled individuals.
  • 20.  When crossing homozygous recessive parents (pp x pp), all of the offspring will be horned (homozygous recessive) individuals.
  • 21.  Crossing a heterozygous parent with a homozygous dominant parent (Pp x PP), the expected offspring would occur in a 1:1 ratio of homozygous dominant to heterozygous individuals.  Phenotype:  All offspring would be polled.
  • 22.  We have a Angus Bull and a Charolais Cow.  The Angus (black) is Homozygous Dominant  The Charolais (white) is Homozygous Recessive  How would you set up the Punnett Square? Punnett Square Example
  • 23.  When crossing a homozygous dominant parent with a homozygous recessive parent (PP x pp), all offspring would be heterozygous and polled.
  • 24.
  • 25.  If two heterozygous parents are crossed (Pp x Pp), one can expect a genotypic ratio of 1:2:1, with one homozygous dominant polled, two heterozygous polled, and one homozygous recessive horned individuals.  The expected phenotypic ratio of offspring would be 3:1 (polled to horned).
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  • 28. Objectives  Explain Gregor Mendel’s laws of inheritance  Discuss the difference between genotypes and phenotypes  Label the three types of genotypes  Draw and label a Punnett square  Predict outcomes of a Punnett square