Medical Quiz; A part of Quitzkrieg 2017, the annual AIIMS Delhi Quiz fest under Pulse 2017. QMs: Sneha Mohan, Srividya, Lajja, Dev (and also, Satwik and Utkarsh)
6. 3. Following is the ecg record of a
patient with deviation in the mean
axis. Predict whether it is left/right
axis deviation and give the
range(quadrant). Eg.0 to 90 degrees
8. 5. A Journal of General Internal Medicine
study, published in 2010, investigated medical
errors from 1979 to 2006 in United States
hospitals and found that medication errors
increased 10% during the month of July , but
not in neighbouring private hospitals. Surgical
errors did not increase, leading to the
hypothesis that medication errors are easier
for new personnel to make because surgical
procedures are done through team work.
This study, though debunked by other studies
gave rise to a popular myth, X. In UK, this has
also been called Black Wednesday, or Killing
season, after usage in a British medical drama
series, Cardiac arrest. What is X?
9. with the center as
the ear canal and its
base extending
outwards along
which our ear is
incapable of
determining the
spatial source of the
sound using only
inter-aural time and
intensity differences.
How then are we
still able to localise
10. 7. Damage to which muscle
and nerve is causing the
gait shown in the video?
(part points – 0.5 +0.5)
11. 8. Why would a patient of
Chronic Granulomatous
Disease be more likely to
suffer from infections due to
Staphylococcus aureus?
12. 9. Identify the tumor shown above. Prior
to surgically removing this tumor, which
class of drugs are to be used first? (Part
points – 1 +1)
13. 10.The following are a part of an
exhaustive list. What is this list?
1. Essential fatty acid
2. Riboflavin
3. Biotin
4. Alcoholic extract of rice
5. Bioflavinoids
15. 12. ‘Whoonga’ is a drug cocktail
smoked by individuals in South
Africa. Among other drugs, this
is said to contain antiretroviral
medications which have been
either stolen from those
infected with HIV or sold by
them on the black market. The
predominant ARV in this drug
cocktail has been found to have
effects similar to LSD, sharing
receptors in the brain. This
results in it’s psychoactive
effects, including hallucinations,
vivid dreams and night terrors.
Name the drug and the class it
belongs to? (part points- 1+0.5)
16. 13. In a child with egg, peanuts
and pollen allergy, which common
vaccine is contraindicated and
why?
17. 14. A Zinc smelter is brought to the
casualty with vomiting and diarrhoea
with rice water stools. O/E breath
has garlicy odour. What is the most
likely ECG finding?
18. 15. Natalizumab is a monoclonal
antibody used to treat multiple
sclerosis and Crohn's disease. It acts
as an antibody against molecules
that reduces the ability of immune
cells to cross the blood brain barrier
and the intestinal wall.
1. What molecule does it target?
2. Which condition would a patient
receiving this drug be more
susceptible to? (part points- 1+1)
19. 16. John Moore was a surveyor on the Alaska Pipeline who developed
bleeding gums, bruising and an enlargement of the abdomen. He was
diagnosed of ______ cancer. When they removed his spleen, it weighed
22 pounds whereas a normal spleen is just around 1 pound. The
following laboratory values are found:
WBC- 3,000/mm3
Platelets – 78,000/mm3
Neutrophils- 1600/mm3
Basophils-4/mm3
Eosinophils-60/mm3
His doctor, David Golde, without taking any consent from Moore, had
filed a patent on Moore's cell line called Mo and its market value was
estimated to be $3 billion. Moore filed a lawsuit against the doctor
asking for his share. Identify the cancer.
20. 17.Macular sparing i.e. loss of peripheral
vision with intact macular vision occurs
because the macular area in the cortex
has dual arterial supply. Name and
identify the arteries involved on an
angiogram.
A
B
C
D
22. 19.Pituitary infarcts are rare but in
women who have an episode of
shock due to PPH, the pituitary
become infarcted. Why are these
women especially vulnerable to
these infarcts?
24. 21. A woman has a regular menstrual
cycle of 37 days duration. What is the
duration of her follicular and luteal
phases? Menstruation is for 4 days.
25. Scientific American :'Surprisingly,
even plants which use chlorophyll to
absorb light energy can suffer from a
condition analogous to X. The plant
disease causes the leaves to blister,
wither and die on exposure to
sunlight. The process is so similar to
the human condition X that some
researchers hope to find a cure for
the disease human condition by
studying the properties of so called
"vampire plants" like maize. ' Which
26. 23.Why is the upstroke of pacemaker
potential due to calcium channels
and not fast sodium channels unlike
myocyte potential or nerve
potential?
32. 29. A young male
patient presented with
severe renal colic. The
observation made from
urinalysis is shown in
the image.
1. What is this finding?
2. What
gastrointestinal
pathology is he likely
to have?
(Part points will be
33. including the head. They are caught with
a particular kind of pots. These pots are
like octopus real estate, and are attached
to a long rope that is dropped into the
water, where they eventually settle on
the sea bottom. The unsuspecting
octopus, who lives on the sea floor,
comes along and says “Wow, a free
house!” and, feeling like he has just won
the lottery, sidles into his new abode,
and is cooked up by the happy hunter.
These pots have been made legendary in
40. 3. Following is the ecg record of a
patient with deviation in the mean
axis. Predict whether it is left/right
axis deviation and give the
range(quadrant). Eg.0 to 90 degrees
44. 5. A Journal of General Internal Medicine
study, published in 2010, investigated medical
errors from 1979 to 2006 in United States
hospitals and found that medication errors
increased 10% during the month of July , but
not in neighbouring private hospitals. Surgical
errors did not increase, leading to the
hypothesis that medication errors are easier
for new personnel to make because surgical
procedures are done through team work.
This study, though debunked by other studies
gave rise to a popular myth, X. In UK, this has
also been called Black Wednesday, or Killing
season, after usage in a British medical drama
series, Cardiac arrest. What is X?
46. with the center as
the ear canal and its
base extending
outwards along
which our ear is
incapable of
determining the
spatial source of the
sound using only
inter-aural time and
intensity differences.
How then are we
still able to localise
54. 10.The following are a part of an
exhaustive list. What is this list?
1. Essential fatty acid
2. Riboflavin
3. Biotin
4. Alcoholic extract of rice
5. Bioflavinoids
58. 12. ‘Whoonga’ is a
drug cocktail smoked
by individuals in South
Africa. Among other
drugs, this is said to
contain antiretroviral
medications which
have been either stolen
from those infected
with HIV or sold by
them on the black
market. The
predominant ARV in
this drug cocktail has
been found to have
effects similar to LSD,
sharing receptors in
the brain. This results
in it’s psychoactive
effects, including
62. 14. A Zinc smelter is brought to the
casualty with vomiting and diarrhoea
with rice water stools. O/E breath has
garlicy odour. What is the most likely ECG
finding?
64. 15. Natalizumab is a monoclonal
antibody used to treat multiple
sclerosis and Crohn's disease. It acts
as an antibody against molecules
that reduces the ability of immune
cells to cross the blood brain barrier
and the intestinal wall.
1. What molecule does it target?
2. Which condition would a patient
receiving this drug be more
susceptible to? (part points- 1+1)
66. 16. John Moore was a surveyor on the Alaska Pipeline who
developed bleeding gums, bruising and an enlargement of
the abdomen. He was diagnosed of ______ cancer. When
they removed his spleen, it weighed 22 pounds whereas a
normal spleen is just around 1 pound. The following
laboratory values are found:
WBC- 3,000/mm3
Platelets – 78,000/mm3
Neutrophils- 1600/mm3
Basophils-4/mm3
Eosinophils-60/mm3
His doctor, David Golde, without taking any consent from
Moore, had filed a patent on Moore's cell line called Mo
and its market value was estimated to be $3 billion. Moore
68. 17.Macular sparing i.e. loss of peripheral
vision with intact macular vision occurs
because the macular area in the cortex
has dual arterial supply. Name and
identify the arteries involved on an
angiogram.
A
B
C
D
72. 19.Pituitary infarcts are rare but in
women who have an episode of
shock due to PPH, the pituitary
become infarcted. Why are these
women especially vulnerable to
these infarcts?
76. 21. A woman has a regular menstrual
cycle of 37 days duration. What is the
duration of her follicular and luteal
phases? Menstruation is for 4 days.
78. Scientific American :'Surprisingly,
even plants which use chlorophyll to
absorb light energy can suffer from a
condition analogous to X. The plant
disease causes the leaves to blister,
wither and die on exposure to
sunlight. The process is so similar to
the human condition X that some
researchers hope to find a cure for
the disease human condition by
studying the properties of so called
"vampire plants" like maize. ' Which
92. 29. A young male
patient presented with
severe renal colic. The
observation made from
urinalysis is shown in
the image.
1. What is this finding?
2. What
gastrointestinal
pathology is he likely
to have?
(Part points will be
94. including the head. They are caught with
a particular kind of pots. These pots are
like octopus real estate, and are attached
to a long rope that is dropped into the
water, where they eventually settle on
the sea bottom. The unsuspecting
octopus, who lives on the sea floor,
comes along and says “Wow, a free
house!” and, feeling like he has just won
the lottery, sidles into his new abode,
and is cooked up by the happy hunter.
These pots have been made legendary in
121. Mermaid syndrome or sirenomelia-
an extreme case of caudal
regression syndrome
122. “And the LORD sent fiery serpents among the
people, and they bit the people; and much people
of Israel died. Therefore the people came to
Moses, and said, We have sinned, for we have
spoken against the LORD, and against thee; pray
unto the LORD, that he take away the serpents
from us. And Moses prayed for the people. And the
LORD said unto Moses, Make thee a fiery serpent,
and set it upon a pole: and it shall come to pass,
that every one that is bitten, when he looketh
upon it, shall live."
This Fiery serpent on the pole, now a rampantly
used symbol is hence interpreted as a direct
treatment of a particular ailment by some modern
125. 4. Symptoms of this condition include bruit,
progressive visual loss, pulsatile proptosis.
Patients usually present with sudden onset of
redness in an eye associated with progressive
proptosis.
Identify the vascular anatomical cause of these
symptoms.
128. 5. What is the rationale for
using diphenoxylate and
atropine together in
Lomotil for diarrhoea?
129.
130. Atropine is subtherapeutic. This
combination is to ensure that if a
person tries to take the opioid in
excess, he’ll then have atropine side
effects.
136. Coenzyme Q is produced from
cholesterol, which is necessary in
the electron transport chain.
137. 8. Increased activity can lead to muscle
cell hypertrophy which increases
contractility. Alternatively, inactivity can
lead to muscle cell atrophy and loss of
contractile strength. Comment on the
relative susceptibility of Type 1 fibres to
these processes compared to Type 2
fibres and explain why.
138.
139. Type 1 are more susceptible to
atrophy and less to hypertrophy
compared to type 2 fibres
142. Hint
X, developed by David Ferruci, and named after
Thomas Watson, was original designed to answer
questions on Jeopardy!; winning the first million
dollar prize against the former winners in 2011In
2013, X’s team announced that its first commercial
application would be for utilisation management
decisions in Lung Cancer treatment at Memorial
Sloan Kettering Cancer Institute, New York City. 90%
of the nurses in the field now use X for guidance. X
has partnerships with several institutes, including the
Cleveland Clinic and Manipal Hospitals here in India.
146. • This round has 7 questions.
• Each question has three or four components
which are connected to each other in one
specific way.
• Pounce +15 for connect and +5 for
explanation, and -10 for wrong connect and
no negative for wrong explanation.
• Infinite bounce +15 for connect and +5 for
explanation. No negatives.
170. • There are 5 questions in this round.
• Each team gets 125 points to bid at the
beginning of the round.
• Five topics will be presented together before
the round starts.
• The topics are for a broad idea of what the
question will be.
• The teams have to allocate each topic certain
points, the total of which will be 125 or less.
• Say, the team allots X points to a particular
topic. They will get +X if they answer right,
173. Stanley Gartler was the first scientist to establish
clonality of human cancers. At a conference on
Cell Tissue and Organ Culture, he presented a
work in which he had found that 18 of the most
commonly used cell culture had a gene called
______ in common. This marker is common in
African Americans. The manifestations of
mutation in this gene are common in certain
countries because of their food habits. So, his
results implied that those 18 cell lines were
contaminated by the vigorously growing HeLa cell
line obtained from a black woman. His work was
178. was a very important step towards higher
efficiency, because information can be stored
much more economically.
Another theory is that the Y Structure of
genes is a relic of the RNA world, a
hypothetical phase of the evolutionary history
of life on Earth, in which self-replicating RNA
molecules proliferated before the evolution of
DNA and proteins.
X creates smaller RNA molecules, which act as
functional ribozymes and membranes, from
the larger genomes enabling a self sufficient
RNA unit, without the initial necessity of
protein. X is also the reason why the
proteome is bigger than the genome. The
video shown has an item related to the
197. • There are 6 questions in the round.
• Each of the answers goes into a megaconnect.
• The teams can guess the megaconnect after every
question.
• All teams get to answer all questions.
• The scoring pattern is a differential one.
• The score for each question is 3n+5 where n is the number
of teams that get it wrong.
• There are no negatives for individual questions.
• The scoring for megaconnect is as follows-
• +60, -10; +50,-15; +40, -20; +30, -25; +20, - 30; +10, - 40
198. 1. ABO incompatibility
mostly does not cause any
transfer of antibodies
across placenta but Rh
incompatibility does.
201. which is as follows. A protein X, allows yeast to
use ureidosuccinate in the presence of
ammonium ion. Chromosomal mutations in
the Y gene produces X. X depends for its
propagation on the Y product. Saccharomyces
cerevisiae strains cured of X were shown to
return to the X-carrying state without its
introduction from other cells. Overproduction
of Y increased the frequency with which a
strain became X by 100-fold.
This experiment acted as an independent
evidence for an ongoing controversy about the
existence of another protein during that time.
204. Astronauts experience diuresis in the
early stages of their stay in space. In
a research, one of their tissue
samples is found to contain a higher
level of cGMP. Explain the
mechanism of diuresis.