A poster representation for a brief outline of the prevention and vaccines for Malaria

1. PREVENTION OF MALARIA AND MALARIAL VACCINES
BY PRIYANKA BHARATHIDASAN, 2ND YEAR MBBS, RA1841002010103, SRM MEDICAL COLLEGE AND RESEARCH CENTRE
INTRODUCTION
Spread by mosquitos, malaria is one
of the most common infectious
diseases and a global public health
challenge.
Iit is caused by a plasmodium
parasite, transmitted by the bite of
infected mosquitoes.
It can be prevented through many
methods and malarial vaccines are
also made available.
Today, the most advanced malaria vaccine is
RTS,S, a pre-erythrocytic stage vaccine
consisting of a virus-like particle (VLP) that
displays hepatitis B surface antigen alone (S)
and fused with a P. falciparum circumsporozoite
protein fragment containing its central repeats
and T cell epitopes (RTS). RTS,S has
completed Phase III clinical trial (vaccine given
to thousands of people and tested for efficacy
and safety) and showed an efficacy of 51.3%
against clinical malaria. It induces the CD4T
cells but not CD8T cells in humans.
RTS,S Vaccine