Babesia induced Multiorgan failure in a Dog with special focus on Chronic Kidney Disease
1. Therapeutic Management of Babesia
induced Chronic Kidney Disease in Dog
Presented By : 4th Year BVSc & AH,
1. Zotluangpuii(2019-v-63).
2. Mohit Gupta(2019-v-64)
3. V.L.Rinchhana(2019-v-65)
4. PremAggarwal(2019-v-66)
5. Angel Malsawmtluangi (2019-v-67)
6. Debbie Lalhruaitluangi (2019-v-70)
Group 10 VCP II Case Presentation
2. Introduction
Chronic kidney disease (CKD) is defined by presence of functional
or structural impairment in 1 or both kidneys for more than
approximately 3 months.
Familial
Acquired
Congenital
1 in 10 Dogs
1 in 3
Cats
3.
4.
5.
6.
7. Anamnesis
Case No: 799
Date: 08/12/22
Owner Name: Lalrohlua
Address: Durtlang
Phone No: 9383062949
Species: Canine
Breed: Pitbull
Sex: Male
Colour: Black
Age: 1 Year
Body Weight: 13.5 Kg
No food intake since
yesterday (07/12)
Vomited once
yesterday (yellowish).
Reddish brown
diarrhoeaa from
yesterday.
Vaccinated with ARV
& Dewormed last year.
No history of ticks
infestation, presence of
fleas.
Observations
HR: 94 bpm
RT:99.8 ºF
MM: Congested
CRT: 1 Sec
STT: 4 Secs
Body Weight: 13.5 kgs
Signalment
10. Urea - 216.6mgs%
Creatinine - 5.7 mgs
Total Protein - 6.0 % gm/dL
Albumin - 3.0 gm %
Globulin - 3.0 mgs %
Total Bilirubin - 0.5 mgs
Direct - 0.2 mgs
Indirect - 0.3 mgs
SGPT - 26 IU/L
SGOT - 21.0 IU/L
ALP – 161.0 IU/L
15-40 mgs %
0.8-1.4 mgs
5.4-7.5 % gm/dL
3.5-5 gm %
3.0 mgs %
0.2-1 mgs %
0-0.2 mgs
0.2-0.8 mgs
0.0-42 IU/L
0.0-43 IU/L
1-114 IU/L
Serum Biochemistry Results:
Patient’s Results Normal Range
WBC - 21.1 K/µL
Grans – 18.1 K/µL
HGB – 7.9 g/dL
PLT – 83 K/µL
HCT – 22.9 %
MCHC – 34.5 g/dL
0.6-17
3.3-12
12.0-18
175-500
37-55
30-10
Normal Range
Patient’s Results
Hematology Results:
The dog teste positive for Babesia gibsoni ,afterwhich triple
drug therapy was initiate for 28 days, alongwith it
threatment for 4th stage kidney failure or CKDwas started
from this day onward.
11. Clindamycin @
25 mg/kg PO BID
Metronidazole
@ 10 mg/kg PO
BID
Doxycycline
@ 5 mg/kg PO, OD
28
Days
Triple
Therapy
12. Treatment for CKD
Tab. Envas (Enalapril)
@ 0.25 mg/kg B.W., PO,
BID
Tab Lasilactone
@ 2 mg/kg B.W., PO, q24h
Inj. Sodium Bicarbonate
(5%)
8-12 mg/kg, PO. q8h
Tab. Renoflex
1 Tab/20Kg B.W., PO. BID
Tab. Rubenal
½ Tab BID FOR 8-12 Kg
B.W.
Syp. PetsApp
0.5 mL /Kg B.W.
Syp. Digene
2 tsp. BID, before foo
Renal Diet
As per manufacturer
13. No Vomiting, Defecated once,
Blackish stool, Anorexia, Normal
water intake
Purulent nasal
Discharge, twitching,
arrhythmia, chewing
gum seizure
No vomiting, anorexia,
no Defecation, urinate
twice, normal water
intake
Little amount of foo
intake, no Defecation,
no vomiting, urine
output increase
Little amount of foo
intake, no vomiting, no
Defecation, increase
urine output, cold
extremities
9.12.2022 10.12.22 11.12.22 12.12.22 13.12.22
MM- Pale, STT- 3 sec, CRT- 1
sec, HR- 90bpm, RT-102.1 F
MM- Pale Pink,
STT- 4 sec, CRT- 2
sec, HR- 85bpm,
RT-100.5 F
RT-101.3F, HR-
107bpm, STT-3sec,
CRT-2sec, MM-
pale
RT-100.5F, HR-
110bpm, STT-
5sec, CRT- 2sec,
MM- pale pink
RT-97.8F@10:35am
,100F @11:50am,
HR- 90bpm, MM-
pale pink, CRT-
2sec, STT- 4sec
Ondan Stopped
Treatment for
CKD
CST CST CST
Date
Management
Parameters
Observation
14. Body weight decreased(12.10kg),
little food intake, normal water
intake, normal urination.
Normal food intake,
normal urination,
normal defecation,
normal water intake,
no vomition and no
diarrhea
Normal food and water
intake, normal
defecation, no
vomition, increased
urination
No vomition, no
diarrhea, normal food
and water intake,
increased urination.
Normal food intake,
normal urination and
defecation.
14.12.2022 15.12.22 16.12.22 17.12.22 19.12.22
MM- Pale pink, STT- 5 sec,
CRT- 2 sec, HR- 93bpm,
RT-98F F
MM- Pale Pink,
STT- 5 sec, CRT-
2 sec, HR-
98bpm, RT-100.1
F
RT-100.2F, HR-
107bpm, STT-
3sec, CRT-2sec,
MM- pale pink
RT-99.7F, HR-
98bpm, STT-
2sec, CRT- 2sec,
MM- pink
RT-99.9F, HR-
90bpm, MM-pink,
CRT- 2sec, STT-
2sec
CST CST CST CST
Tab. Wysolone @1/2
tab. PO BID for 5 days
Date
Management
Parameters
Observation
16. After 17 days of treatment for Babesia induced CKD, the
animal is in normal health and well being and further
complications had not been yet reported.
Prognosis