Veterinary Virology

1. Last Part of the Viral
Replication

2. Unique Viral Replications

3. Unique Viruses
• Production of Viroplasm or also known as “Inclusion bodies”.
Baltimore's
classification
Family Species
Site of
Infection
I: dsDNA
Poxviridae
Asfarviridae
Iridoviridae
Mimiviridae
Herpesviridae
vaccinia virus
African swine fever virus
frog virus
Acanthamoeba polyphaga
mimivirus
Pithovirus
Herpes simplex virus
CYTOPLASM
III: dsRNA Reoviridae Avian reovirus CYTOPLASM
IV: (+)ssRNA
Togaviridae
Flaviviridae
Rubella virus
Flavivirus
CYTOPLASM
V: (−)ssRNA
Rhabdoviridae
Peribunyaviridae
Rabies virus “Negri Bodies”
Orthobunyavirus
CYTOPLASM
VI: ssRNA-RT Retroviridae Human immunodeficiency virus CYTOPLASM
VII: dsDNA-RT Caulimoviridae Cauliflower mosaic virus CYTOPLASM

4. • In Veterinary important Viruses.
• All RNA viruses replicate in cytoplasm, except Orthomyxoviruses and
Retroviruses that have replicative stages in nuclei.

5. VIRAL FAMILIES AND THE
DISEASE THEY CAUSE
We will only focus on the Diseases that is veterinary important
• HERPESVIRIDAE
• POXVIRIDAE

6. TYPES OF TROPISM
Viral tropism is the ability of different viruses to infect different cellular types ultimately to produce a
successful infection. Being parasitic entities, cellular tropism is one of the major characteristics of viruses to
maintain a successful infectious cycle in target cells

7. HERPESVIRIDAE

8. HERPESVIRIDAE
• A large diverse family of DNA virus (Actually the largest)
• Are large in size and noted for their ability to cause latent infection
• They are enveloped, double stranded DNA Viruses with an icosahedral capsid
• Divided into three sub-families
• 1. Alphaherpesvirinae
• 2. Betaherpesvirinae
• 3. Gammaherpesvirinae

9. ACTIVITY AREA (Pathogenesis of Herpes Virus 1 and 2)
• Transmission: Most of
the time DIRECT
CONTACT
- Can also be contact
with HSV in herpes
lesions, mucosal
surfaces, genital
secretions, or oral
secretions
• Distribution of
RECEPTORS:
- Macrophages
- Dendritic Cells
• TROPISM
- Epithelial cells
- Neurons
• Answers:

10. LIST OF DISEASES
• Infectious bovine rhinotracheitis
• Malignant catarrhal fever
• Equine rhinotracheitis
• Equine herpesvirus abortion
• Canine herpesvirus infection
• Feline viral rhinotracheitis
• Infectious laryngotracheitis
• Marek’s disease.