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AnAIdrivenhealthcareplattform
thenextstepintelemedicine
PhilipVollet|symplytics_
October14,2017.
•How?
-Betteranamnesis
-Betterdiagnosis
-Bettersupervision
-Bettertreatmentoptionsandhealth
Whatwewanttosolve:betterhealthcareforeveryone
•Treatmentbyambulantdoctorsoftendoesnotfollowthelatest
scientificknowledgeandtreatmentapproaches
•Betterdierentiationandclusteringofdiseasepatternsfor
bettertreatmentoptions
•Directintegrationofmedicaldevicesandrecordingofdatafor
analysisandtreatment
Betteranamnesis&diagnosis
Disease-Graph
NewTab Microsoft
MicrosoftEdge
→
Betterclustering&dierentiation
•Depressionisanumbrellatermformanysymptoms,
diseasesandmooddisorders
•Tinnitusisnotjusttinnitus.It'samultitudeofsometimes
similarsymptomsthathavetodowiththeears
•MigraineWithoutAura,HemiplegicMigraine,
OphthalmoplegicMigraine,VestibularMigraine,BasilarMigraineetc.
••Addictioninrelationtosubstancesasdierentdrugclassesand
variationofreceptortargets,ImpulseControlDisorders,Behavioral...
Betterclustering&dierentiation
(:Drug)-[:TARGETS]-(:Gene)-[:ASSOCIATES]-(:Disease)
(:Drug)-[:REGULATES]-(:Gene)-[:INTERACTS]-(:Gene)-[:ASSOCIATES]-(:Disease)
(:Drug)-[:CAUSES]-(:SideEect)-[:CAUSES]-(:Drug)-[:TREATS]-(:Disease)
Betterclustering&dierentiation
Betterclustering&dierentiation
•Whatistinnitus?
-Asoundinoneorbothears:Usuallysoundslike:ringing,
clicking,hissing,orevenroaringlikeawaterfall
-Loworhighpitched/softorloudetc.
-Asdierentasthenoisefromatinnitusaretheunderlyingcauses
Betteranamnesis&diagnosis(Tinnitus)
•Andcommoncausesfortinnitusinclude:
Noise-InducedHearingLoss,dyinghearingcellsthatarestillmapped
inthebrain,earInfections,diseaseoftheheartorbloodvessels,
musculardisorder,Ménière’sdisease,braintumors,emotionalstress,
exposuretocertainmedications,headInjuriesetc.
Betteranamnesis&diagnosis(Tinnitus)
Betteranamnesis&diagnosis(Tinnitus)
→
Betteranamnesis&diagnosis(Depression)
+
UsingAItoanalyseclinicaltrials,researchpaper,
andscientificstudiesfornewesttreatmentoptions
→
Watchscientificpublications,self-helpcommunity,
relatedreddit:subreddits,messageboards...
A
B
Buildastackoverflowforhealth
Bettertreatmentoptions
→
Biggestchallenges
-GraphandTopologicalStructureMiningonScientificArticles:https://doi.org/10.1002/sam.11153
-MiningGraphData:DOI10.1007/978-3-319-14142-817
-GraphMining:Laws,Generators,andAlgorithms:http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.85.3391
-DiseaseOntology:https://academic.oup.com/nar/article/40/D1/D940/2903651
-WikiPathways:https://academic.oup.com/nar/article/44/D1/D488/2502580
-Hetnetsinbiomedicine:http://het.io/
--Systematicintegrationofbiomedicalknowledgeprioritizesdrugsforrepurposing:https://think-lab.github.io/p/rephetio/
-GeneOntology:toolfortheunificationofbiology:https://www.nature.com/articles/ng0500_25
-BiomedicalTextMiningandItsApplications:https://doi.org/10.1371/journal.pcbi.1000597
-High-definitiontranscranialdirectcurrentstimulationofthedorsolateralprefrontal
cortexfortinnitusmodulation:apreliminarytrial:https://www.ncbi.nlm.nih.gov/m/
pubmed/29127483
-UsingTextMiningTechniquestoIdentifyResearchTrends:www.mdpi.com/2076-3417/7/4/401/pdf
Sources
thankyou

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symplytics