bone marrow transplant is the surgical procedure for replacement of the cancerous or abnormal cells present in the blood or cells and to improve the blood quality and quantity to fight against the diseases and for learning purpose for all the nursing student and application of these knowledge in their clinical practice

1. Bone Marrow Transplantation
DEPARTMENT
OF
MEDICAL SURGICAL NURSING

2. At the end of this lecture, students should be to
Define Bone Marrow Biopsy.
Enlist the Types of BMT.
Describe the Nursing Management of BMT.

4. BMT is a therapeutic modality that offers the
possibility of cure for some patients with
hematologic disorders such as severe aplastic
anemia, some forms of leukemia, and thalassemia.

5. • Allogeneic (from a donor other than the patient)
• Autologous (from patient)
• Syngeneic (from an identical twin)

9. • Implementing Pretransplantation Care
• Providing Care During Treatment
• Providing Posttransplantation Care
• Caring For The Donors

10. • Nutritional assessments,
• extensive physical examinations and
• organ function tests
• psychological evaluations are conducted.

11. • Blood work includes assessing past antigen
exposure
• The patient’s social support systems and
financial and insurance resources are also
evaluated.
• Informed consent and patient teaching about
• the procedure and pre transplantation and post
transplantation care are vital.

14. • Monitoring the patient’s vital signs and
blood oxygen saturation
• Assessing for adverse effects, such as fever, chills,
shortness of breath,
• Providing ongoing support and patient teaching

15. Patients require support with blood products and
hemopoietic growth factors.
Potential infection may be bacterial, viral, fungal, or
protozoan in origin.
Renal complications
Tumor lysis syndrome and acute tubular necrosis
are also risks after BMT.

16.  Graft versus-host disease (GVHD)
Venous Occlusive disease (VOD)
Pulmonary complications, such as pulmonary
edema, interstitial pneumonia, and other
pneumonias, often complicate the recovery after
BMT.

17. • Ongoing nursing assessment
• Late effects include infections, restrictive pulmonary
abnormalities, and recurrent pneumonias.
• Sterility often results.
• Chronic GVHD involves the skin, liver, intestine,
esophagus, eye, lungs, joints, and vaginal mucosa,
Cataracts.
• Psychosocial assessments

18. • Donors commonly experience mood alterations,
decreased self esteem, and guilt from feelings
of failure if the transplantation fails.
• Family members must be educated and supported
to reduce anxiety and promote coping during
this difficult time.

20. So far we have discussed about definition, types and
management of bone marrow transplantation.

21. Lewis et al, Medical Surgical Nursing, Mosby
Elsevier,7th edition.
Joyce.M.Black et al, Medical Surgical Nursing,
Saunders publication.
Brunner and Siddhartha, Medical Surgical
Nursing, Lippincott Williams and Wilkins.

22. Thank You