1) Thalassemia are inherited blood disorders characterized by abnormal hemoglobin production that causes the body to make less hemoglobin. 2) There are two main types - alpha thalassemia and beta thalassemia - depending on which genes for alpha or beta globins are missing. 3) Symptoms of thalassemia include pale skin, fatigue, enlarged spleen, yellowish skin, dark urine, and slow growth in children. Treatment involves regular blood transfusions, iron chelation therapy to remove excess iron, and possibly bone marrow transplants.

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2. BY
Jahad for Zero Thalassemia (JZT)
ZONAL COORDINATOR
Harappa Zone
MUHAMMAD TAQI UL MAIRAJ
University of Engineering and Technology
Lahore
(RCET CAMPUS)
Thalassemia
Awareness

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Thalassemia are inherited BLOOD DISORDERS
characterized by abnormal HEMOGLOBIN production.
It causes your body to make less Hemoglobin.
Also known as Thalassemia Major , Mediterranean
and Anemia.
Thalassemia are GENETIC DISORDERS inherited
from a person’s PARENTS.

5. Types
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It has tow types:-
1) Alpha Thalassemia
2) Beta Thalassemia
Depends upon missing of ALPHA and BETA
globins.
How many of four genes for Alpha or two
genes for Beta globins are missing.

6. It Causes
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 Pale Skin
 Tired
 Enlarged Spleen
 Yellowish Skin
 Dark Urine
 Slow Children growth

7. Thalassemia Minor
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 Thalassemia trait in one gene are knowns as
CARRIES or THALASSEMIA MINOR.
 Thalassemia minor has no SYPTOMS only
BLOOD EXAMINATION can detect it.
 Probabilty of Thalassemia Minor is 50%

8. Diagnostic Method
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A. BLOOD TESTS
B. GENETIC TESTS
 A Complete Blood Count (CBC) reveals
Anemia.
Red Blood cells will appears Smalls and

9. Diagnostic Method
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Abnormally shaped when looked at under a
microscope.
A test called Hemoglobin Electrophoresis shows
the presence of abnormal forms of Hemoglobin.
A test called Mutational Analysis can help detect
Alpha Thalassemia that cannot be see with
Hemoglobin Electrophoresis.

10. Treatment
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1) BLOOD TRANSFUSIONS
2) IRON CHELATION
3) FOLIC ACID
4) BOWN MARROW TRANSPLANT
Iron Chelation may be done with Deferoxamine
or Defersirox.
Iron overload from the transfusion will resulting
Heart or Liver Diseases.
If Spleen becomes overly enlarged Surgical
removal may be required.

11. Treatment
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 Bone Marrow Transplant May be an Option.
 It is most commonly in Italians, Greeks, Middle
Eastern , South Asian and Africans.
 Male and Females have similar rates of
Disease.
 36000 deaths in 1990
 16800 deaths in 2015

12. It’s Compulsory
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At the time of engagement it is essential that
both are not Thalassemia Minors. If so , their
children may suffer from Thalassemia Major
which requires Blood transfusion every month.

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15. What Should we do
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 Give Awareness about Thalassemia in your
Society.
 Donate blood for Thalaseemia Patient.

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17. Thank You
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