Diabetes Mellitus Management in CKD (Clinical Tips) - Dr. Gawad

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Health & Medicine

Diabetes Mellitus Management in CKD
Clinical Tips
Mohammed Abdel Gawad MD, ESENeph
Lecturer of Nephrology, School of Medicine, NewGiza University
Founder of NephroTube.com
ISN Education SoMe Team Member
Co-chair of AFRAN Web/Media Committee
23/March/2022

To download the lecture
contact me
drgawad@gmail.com
For more Nephrology lectures visit
www.NephroTube.com

Risk of hypoglycemia
increases with CKD
progression due to 3 causes
Renal gluconeogenesis is
impaired owing to lower
kidney mass, and the
clearance of insulin and oral
diabetes medications
decreases as CKD progresses
Anorexia and weight loss
related to uremia can also
increase hypoglycemia risk.
The risk for hypoglycemia
increases as GFR declines,
primarily in those taking
insulin, sulfonylureas, or
glinides.
Am J Kidney Dis. 2021 Sep 29;S0272-6386(21)00762-9

Am J Kidney Dis. 2021 Sep 29;S0272-6386(21)00762-9

J Am Soc Nephrol. 2017 May 2. in press
10

Glucagon-like peptide-1 Gastric inhibitory polypeptide
Diabetologia. 2016 May;59(5):907-17
DPP4-i DPP4-i
Incretins
Incretin
mimetic
(GLP-1 RA)

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