Mushroom poisoning is poisoning resulting from the ingestion of mushrooms that contain toxic substances. Its symptoms can vary from slight gastrointestinal discomfort to death in about 10 days. Mushroom toxins are secondary metabolites produced by the fungus. Amanita virulent fungus; Fungal pathogens possess virulence factors that allow them to cause disease in humans and animals. All toxic mushrooms cause vomiting and abdominal pain; other manifestations vary significantly by mushroom type. Generally, mushrooms that cause symptoms early (within 2 hours) are less dangerous than those that cause symptoms later (usually after 6 hours). The treatment of patients poisoned with amanita muscaria poisoning should be conducted in hospital. Gastric lavage and symptomatic treatment should be carried out as soon as possible. If necessary, restraint or sedation should be employed for agitated and/or delirious patients. Patients hospitalized and given aggressive support therapy almost immediately after ingestion of amanitin-containing mushrooms have a mortality rate of only 10%, whereas those admitted 60 or more hours after ingestion have a 50–90% mortality rate. Presented by: Mohammadsaleh Moallem

1. Treatment options for mushroom poisoning
Presented by: Mohammad saleh Moallem

2. PBL Presentation
Presented by: Mohammadsaleh Moallem
Question:
9. Explain treatment options and medial management for mushroom poisoning?

3. Question:
1. Explain treatment options and medial management for mushroom poisoning?
Mushroom poisoning
Amanita virulent fungus
Fungal pathogens possess virulence
factors that allow them to cause
disease in humans and animals.
3

4. Mushroom poisoning is poisoning resulting from the
ingestion of mushrooms that contain toxic substances. Its
symptoms can vary from slight gastrointestinal discomfort
to death in about 10 days. Mushroom toxins are secondary
metabolites produced by the fungus.
Mushroom poisoning
Question:
1. Explain treatment options and medial management for mushroom poisoning?
4

5. All toxic mushrooms cause vomiting and abdominal pain;
other manifestations vary significantly by mushroom type.
Generally, mushrooms that cause symptoms early (within 2
hours) are less dangerous than those that cause symptoms
later (usually after 6 hours).
Symptoms of
Mushroom poisoning
Question:
1. Explain treatment options and medial management for mushroom poisoning?
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6. Bismuth subsalicylate - treat nausea and diarrhea
Treatment of
Mushroom poisoning
Question:
1. Explain treatment options and medial management for mushroom poisoning?
Loperamide – is Antidiarrheal
Activated charcoal - prevent the poison from being absorbed by stomach
Thoitic acid (alpha lipoic acid) - is a possible antidote to amanita poisons
primary detoxification - by inducing emesis or vomiting
Gastric lavage - empty the stomach of toxic substances
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7. The treatment of patients poisoned with amanita muscaria
poisoning should be conducted in hospital.
Gastric lavage and symptomatic treatment should be
carried out as soon as possible. If necessary, restraint or
sedation should be employed for agitated and/or delirious
patients.
Question:
1. Explain treatment options and medial management for mushroom poisoning?
Treatment of
Mushroom poisoning
7

8. Question:
1. Explain treatment options and medial management for mushroom poisoning?
Gastric lavage
Gastric lavage is a gastrointestinal
decontamination technique that aims to
empty the stomach of toxic substances
by the sequential administration and
aspiration of small volumes of fluid via
an orogastric tube.
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9. Certain types of mushrooms contain very potent toxins
and are very poisonous; So even if symptoms are treated
promptly, mortality is high. With some toxins, death can
occur in a week or a few days.
Although a liver or kidney transplant may save some
patients with complete organ failure, in many cases there
are no organs available.
Question:
1. Explain treatment options and medial management for mushroom poisoning?
Treatment of
Mushroom poisoning
9

10. Patients hospitalized and given aggressive support therapy
almost immediately after ingestion of amanitin-containing
mushrooms have a mortality rate of only 10%, whereas
those admitted 60 or more hours after ingestion have a 50–
90% mortality rate.
Treatment of
Mushroom poisoning
Question:
1. Explain treatment options and medial management for mushroom poisoning?
10

11. Thank you for your attention
Presented by: Mohammadsaleh Moallem
默汉 201816230152