Retinopathy manifestations in Egyptian cirrhotic patients

1. Mohamed ELShafie
Maha Kamal
Yomna Zagloul
Dalia Mahmoud Gad
Menna Alaa
Doaa Abdel Razak
Prepared and presented by

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Contents.
01 INTRODUCTION
02 Unmet clinical need and overall goal
03 Specific aim and hypothesis
04 Preliminary Data
05 Study design
06 Inclusion and exclusion criteria
07
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Anticipated results
Refrences

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there are many chronic diseases affect eye conditions such
as DM, HTN, and liver cirrhosis as well.
“ “
It's known that eye
exams check far more
than your vision

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Liver cirrhosis affects the eye
through various etiologies:
Third hypothesis
retinopathy.
first hypothesis
Xerophthlamia
vitamin A deficiency
Second hypothesis
color blindness

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communication
molecules
from liver to eye

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presentation
to
DesignBall
team
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exact pathophysiology
involving
retinopathy in cirrhosis
is unknown

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prevalence of retinopathy
in cirrhotic patients
relationship between
degree of retinopathy manifestation
& hepatic condition
Aim!

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Retinopathy is a disease
of small retinal blood
vessels.
Notes
Retinopathy is
commonly related to
DM or HTN
Gastroenterologists

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60 cirrhotic patients
in Clinics of Gastroenterology, kafrelsheikh
university Hospital
in a cross sectional study
ultrasonographic
laboratory
Clinical Manifestations

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02
Ophthalmic examination :
03
Best corrected visual acuity
Intraocular pressure (IOP)
applanation tonometry
Fundus examination
pupil dilation with 1% tropicamide drops
04
Imaging of Retina
Heidelberg OCT

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01
adults Egyptian
patients with
cirrhosis.
02
cirrhotic with diabetes patients
hypertension
blood dyscrasias
Behçet’s disease
Inclusion Exclusion

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Anticipated results !!
Prevalence of retinopathy among
cirrhotic patients in Egypt is high.

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Ettl A, Daxecker F. Xerophthalmia in liver
cirrhosis. Correct diagnosis after 15
years. Ophthalmologica. 1992;204:63–66
Abe T, Nakajima A, Satoh N, Koizumi
T, Sakuragi S, Ono T, Komatsu M,
Masamune O. Clinical characteristics
of hepatitis C virus-associated
retinopathy. Jpn J
Ophthalmol. 1995;39:411–419 Leonhartsberger J. Diabetic angiopathy
and liver cirrhosis. Wien Med
Wochenschr. 1978;128:17–19
Colakoglu Onder, Taskiran Bengur, Dayi
Selcuk, Sozmen Bulent, Unsal
Belkis, Maden Ahmet, Pasa Eser, and Aslan
S. Leyla. Relationship between retinopathy
and cirrhosis. 2005 Apr 14; 11(14).
McClain CJ, Van Thiel DH, Parker S,
Badzin LK, Gilbert H. Alterations in zinc,
vitamin A, and retinol-binding protein in
chronic alcoholics: a possible
mechanism for night blindness and
hypogonadism. Alcohol Clin Exp
Res. 1979;3:135–141.

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THANK YOU
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