ARMD Updates antioxidents Divert Lab

1. Mohamed Ahmed
ELShafie
MD, HMS alumni

2. Prevalence

7. Progression
of GA

11. TTT

14. Loss of
Follow Up

16. ASRS 2021

18. AMD , Zinc
Deficiency &
Oxidative
Stress

19. Slow Down Progression of AMD

20. Which Zinc !!!

21. • Fish oil is rich in omega-3 long-
chainpolyunsaturated fatty acids (LCPUFA).
• Christen (2011):
– Consumption of 1 or more of fish per week
associated with a 40% lower risk of developing CNV.

22. AREDS-1 Formula:
Vitamin C: 500 mg
Vitamin E: 400 iu
Beta carotene: 15 mg
Zinc: 80 mg
Copper: 2 mg
AREDS-2 Formula:
Vitamin C: 500 mg
Vitamin E: 400 IU
Zinc: 80 mg
Copper: 2 mg
Lutein: 10 mg
Omega-3 fatty acids

24. Slow Down Progression of AMD
Maintaining Visual Acuity & Reducing
ROS to Decrease AMD Progression
Stimulating Autophagy &
Decreasing Progression of AMD

25. Slow Down
Progression of AMD

26. Slow Down The Progression Of Diabetic Retinopathy

28. THANK YOU

29. Dual Target Therapy

30. VEGF-A

31. Angiopoietin 2

32. Faricimab

35. Risk Factors of DME

39. • Macular Pigment: Lutein and zeaxanthin
– Protect the retina from photochemical damage by
absorbing blue light.
• Lutein supplementation may decrease the
risk of AMD progression in persons with low
dietary intake.