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SHS.202 Lec-05
Dr. Savera Jabeen
Motor System
Basic Concepts
Functions of Motor System
The most important functions of the motor
system are to maintain posture and to exhibit
different movements which ultimately
depend upon contractions of skeletal
muscles.
These motor activities occur at conscious as
well as subconscious levels.
Motor Neurons
Contraction of skeletal muscles
occurs under the control of a set of
neurons called motor neurons.
Each motor neuron and the muscle
fibers innervated by it constitute a
motor unit.
Upper Motor Neurons
Neurons in the higher centers of brain
which influence the lower motor neurons.
They are present in:
a.Cerebral cortex.
b.Basal ganglia.
c.Brainstem.
d.Cerebellum.
Lower Motor Neurons
They innervate the skeletal muscles
directly.
They include:
a.Motor nuclei of cranial nerves in
brainstem.
b.Alpha and Gamma motor neurons in
anterior horn of gray matter of spinal cord.
Alpha and Gamma Motor Neurons
There are 2 types of motor neurons in
anterior horn of gray matter of spinal cord:
a.Alpha motor neurons – Larger; Innervate
extrafusal muscle fibers.
b.Gamma motor neurons – Smaller;
Innervate intrafusal muscle fibers.
They are always coactivated (alpha-
gamma coactivation).
Interneurons
Present in all areas of gray matter of spinal
cord.
They are interconnected to each other as
well as to alpha and gamma motor
neurons.
Most of the signals from sensory spinal
nerves as well as from higher centers
(brainstem, cerebral cortex) are indirectly
transmitted to alpha and gamma motor
neurons via interneurons.
Types of Muscle Fibers
Extrafusal muscle fibers – Larger; Constitute the majority
of skeletal muscle; Innervated by alpha motor neurons;
Used to generate force.
Intrafusal muscle fibers – Smaller; Innervated by gamma
motor neurons; Take part in formation of muscle spindles.
a. Nuclear bag fibers – Larger; Nuclei arranged in a
central “bag” region.
b. Nuclear chain fibers – Smaller; Nuclei arranged in
chains; More abundant than nuclear bag fibers.
Muscle Spindle
Spindle-shaped organs composed of intrafusal
muscle fibers and innervated by both sensory and
gamma motor nerve fibers.
Arranged “in parallel” with extrafusal muscle fibers.
Muscle spindles are the stretch receptors that
detect the change in length of a muscle.
Golgi Tendon Organ
Found in tendons of the muscles.
Arranged “in series” with the extrafusal
muscle fibers.
Detect change in tension of a muscle.
Innervated by sensory nerve fibers.
Spinal Cord Reflexes
Reflex Arc
Motor responses to specific kind of stimuli without
involvement of higher centers is called reflex.
The neuronal circuit that directs this motor
response is called reflex arc. It includes:
a.Sensory receptor.
b.Sensory nerve.
c.Interneuron in spinal cord.
d.Motor neuron.
e.Effector muscle.
Types of Reflexes
a.Monosynaptic – Involves only one
synapse; Example: Stretch reflexes e.g.,
Knee-jerk reflex.
b.Disynaptic – Involves two synapses;
Example: Golgi tendon reflexes e.g.,
Clasp-knife reflex.
c.Polysynaptic – Involves multiple synapses;
Example: Flexor-withdrawal reflexes e.g.,
Withdrawal after touching a hot stove.
Stretch Reflex (Monosynaptic)
Muscle is stretched
Increase in the firing rate of sensory nerve fibers
arising from muscle spindles
Sensory nerve fibers enter spinal cord and activate
alpha motor neurons innervating that muscle
Contraction of the muscle that was stretched
Golgi Tendon Reflex (Disynaptic)
Contraction of the muscle
Increase in the firing rate of sensory nerve fibers
arising from Golgi tendon organs
Sensory nerve fibers enter spinal cord and
activate inhibitory interneurons
Inhibitory interneurons inhibit the firing of alpha
motor neurons
Relaxation of the muscle
Flexor-Withdrawal Reflex (Polysynaptic)
Painful stimulus
Increase in the firing rate of sensory
nerve fibers
Sensory nerve fibers enter spinal cord and
synapse on multiple interneurons
Interneurons activate the alpha motor neurons innervating ipsilateral
flexors and contralateral extensors while inhibit the alpha motor
neurons innervating ipsilateral extensor and contralateral flexors
Flexion (withdrawal) on ipsilateral side and extension on
contralateral side (crossed-extension reflex)
Functions of Spinal Cord Reflexes
a.To maintain steady posture.
b.To ensure quick withdrawal from a noxious
stimuli to avoid injury.
c.To prevent overstretching of muscle fibers.
d.To control the tension of an active muscle.
Descending Pathways
Introduction
Motor pathways descend from upper
motor neurons (present in the cerebral
cortex and brainstem) and influence
lower motor neurons in the anterior horn
of spinal cord.
Types of Descending Pathways
Descending motor pathways are of 2
types:
a.Pyramidal tracts – From cerebral cortex.
b.Extrapyramidal tracts – From brainstem.
Control of Posture &
Movement by Brainstem
Introduction
Brainstem consists of:
a. Medulla oblongata.
b. Pons.
c. Midbrain.
Brainstem influences the motor activities
by means of extrapyramidal tracts taking
origin from brainstem and terminating in
anterior horn of spinal cord.
Extrapyramidal Tracts
They include:
a.Rubrospinal tract.
b.Pontine reticulospinal tract.
c.Medullary reticulospinal tract.
d.Lateral vestibulospinal tract.
e.Tectospinal tract.
Rubrospinal Tract
Origin – Red nucleus (midbrain).
Function – Facilitation of flexor muscles
and inhibition of extensor muscles.
Lateral Vestibulospinal Tract
Origin – Lateral vestibular nucleus
(medulla oblongata).
Function – Facilitation of the extensor
muscles and inhibition of the flexor
muscles.
Pontine Reticulospinal Tract
Origin – Pontine reticular formation.
Function – Generalized facilitatory effect
on both flexors and extensors.
Medullary Reticulospinal Tract
Origin – Medullary reticular formation.
Function – Generalized inhibitory effect on
both flexors and extensors.
Tectospinal Tract
Origin – Superior colliculi (midbrain).
Function – Movement of head and neck
in response to visual stimuli (spinovisual
reflexes).
Questions?
Thank You

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SHS.202 Lec-05 CNS.pdf

  • 4. Functions of Motor System The most important functions of the motor system are to maintain posture and to exhibit different movements which ultimately depend upon contractions of skeletal muscles. These motor activities occur at conscious as well as subconscious levels.
  • 5. Motor Neurons Contraction of skeletal muscles occurs under the control of a set of neurons called motor neurons. Each motor neuron and the muscle fibers innervated by it constitute a motor unit.
  • 6. Upper Motor Neurons Neurons in the higher centers of brain which influence the lower motor neurons. They are present in: a.Cerebral cortex. b.Basal ganglia. c.Brainstem. d.Cerebellum.
  • 7. Lower Motor Neurons They innervate the skeletal muscles directly. They include: a.Motor nuclei of cranial nerves in brainstem. b.Alpha and Gamma motor neurons in anterior horn of gray matter of spinal cord.
  • 8. Alpha and Gamma Motor Neurons There are 2 types of motor neurons in anterior horn of gray matter of spinal cord: a.Alpha motor neurons – Larger; Innervate extrafusal muscle fibers. b.Gamma motor neurons – Smaller; Innervate intrafusal muscle fibers. They are always coactivated (alpha- gamma coactivation).
  • 9. Interneurons Present in all areas of gray matter of spinal cord. They are interconnected to each other as well as to alpha and gamma motor neurons. Most of the signals from sensory spinal nerves as well as from higher centers (brainstem, cerebral cortex) are indirectly transmitted to alpha and gamma motor neurons via interneurons.
  • 10.
  • 11. Types of Muscle Fibers Extrafusal muscle fibers – Larger; Constitute the majority of skeletal muscle; Innervated by alpha motor neurons; Used to generate force. Intrafusal muscle fibers – Smaller; Innervated by gamma motor neurons; Take part in formation of muscle spindles. a. Nuclear bag fibers – Larger; Nuclei arranged in a central “bag” region. b. Nuclear chain fibers – Smaller; Nuclei arranged in chains; More abundant than nuclear bag fibers.
  • 12.
  • 13.
  • 14. Muscle Spindle Spindle-shaped organs composed of intrafusal muscle fibers and innervated by both sensory and gamma motor nerve fibers. Arranged “in parallel” with extrafusal muscle fibers. Muscle spindles are the stretch receptors that detect the change in length of a muscle.
  • 15.
  • 16. Golgi Tendon Organ Found in tendons of the muscles. Arranged “in series” with the extrafusal muscle fibers. Detect change in tension of a muscle. Innervated by sensory nerve fibers.
  • 17.
  • 19. Reflex Arc Motor responses to specific kind of stimuli without involvement of higher centers is called reflex. The neuronal circuit that directs this motor response is called reflex arc. It includes: a.Sensory receptor. b.Sensory nerve. c.Interneuron in spinal cord. d.Motor neuron. e.Effector muscle.
  • 20. Types of Reflexes a.Monosynaptic – Involves only one synapse; Example: Stretch reflexes e.g., Knee-jerk reflex. b.Disynaptic – Involves two synapses; Example: Golgi tendon reflexes e.g., Clasp-knife reflex. c.Polysynaptic – Involves multiple synapses; Example: Flexor-withdrawal reflexes e.g., Withdrawal after touching a hot stove.
  • 21. Stretch Reflex (Monosynaptic) Muscle is stretched Increase in the firing rate of sensory nerve fibers arising from muscle spindles Sensory nerve fibers enter spinal cord and activate alpha motor neurons innervating that muscle Contraction of the muscle that was stretched
  • 22.
  • 23. Golgi Tendon Reflex (Disynaptic) Contraction of the muscle Increase in the firing rate of sensory nerve fibers arising from Golgi tendon organs Sensory nerve fibers enter spinal cord and activate inhibitory interneurons Inhibitory interneurons inhibit the firing of alpha motor neurons Relaxation of the muscle
  • 24.
  • 25. Flexor-Withdrawal Reflex (Polysynaptic) Painful stimulus Increase in the firing rate of sensory nerve fibers Sensory nerve fibers enter spinal cord and synapse on multiple interneurons Interneurons activate the alpha motor neurons innervating ipsilateral flexors and contralateral extensors while inhibit the alpha motor neurons innervating ipsilateral extensor and contralateral flexors Flexion (withdrawal) on ipsilateral side and extension on contralateral side (crossed-extension reflex)
  • 26.
  • 27. Functions of Spinal Cord Reflexes a.To maintain steady posture. b.To ensure quick withdrawal from a noxious stimuli to avoid injury. c.To prevent overstretching of muscle fibers. d.To control the tension of an active muscle.
  • 29. Introduction Motor pathways descend from upper motor neurons (present in the cerebral cortex and brainstem) and influence lower motor neurons in the anterior horn of spinal cord.
  • 30. Types of Descending Pathways Descending motor pathways are of 2 types: a.Pyramidal tracts – From cerebral cortex. b.Extrapyramidal tracts – From brainstem.
  • 31. Control of Posture & Movement by Brainstem
  • 32. Introduction Brainstem consists of: a. Medulla oblongata. b. Pons. c. Midbrain. Brainstem influences the motor activities by means of extrapyramidal tracts taking origin from brainstem and terminating in anterior horn of spinal cord.
  • 33. Extrapyramidal Tracts They include: a.Rubrospinal tract. b.Pontine reticulospinal tract. c.Medullary reticulospinal tract. d.Lateral vestibulospinal tract. e.Tectospinal tract.
  • 34.
  • 35. Rubrospinal Tract Origin – Red nucleus (midbrain). Function – Facilitation of flexor muscles and inhibition of extensor muscles.
  • 36. Lateral Vestibulospinal Tract Origin – Lateral vestibular nucleus (medulla oblongata). Function – Facilitation of the extensor muscles and inhibition of the flexor muscles.
  • 37. Pontine Reticulospinal Tract Origin – Pontine reticular formation. Function – Generalized facilitatory effect on both flexors and extensors.
  • 38. Medullary Reticulospinal Tract Origin – Medullary reticular formation. Function – Generalized inhibitory effect on both flexors and extensors.
  • 39. Tectospinal Tract Origin – Superior colliculi (midbrain). Function – Movement of head and neck in response to visual stimuli (spinovisual reflexes).