1. Curriculum Vitae
I. Personal Information
I.A. Last Name, First Name, Middle Name, Contact Information
Singer, Joshua Harris
Department of Biology
University of Maryland
College Park, MD 20742
Phone: (301)-405-9784
Email: jhsinger@umd.edu
Web: http://biology.umd.edu/faculty/joshuasinger
I.B. Academic Appointments at UMD
Dates Title Institution Department
1/12 – 6/14 Asst. Professor University of Maryland Biology
7/14 – present Assoc. Professor University of Maryland Biology
I.C. Other Employment
Dates Title Institution Department
1/05-12/11 Asst. Professor Northwestern University Ophthalmology
I.D. Educational Background
Degree and date Institution / Mentor Discipline
ScB: May, 1993 Brown University Biology
PhD: August, 1998 Univ. of Washington Physiology
Postdoctoral: 9/98 - 9/2000 NIH / Dr. M. Feller Neurophysiology
Postdoctoral: 9/2000 - 12/2004 NIH / Dr. J. Diamond Neurophysiology
II. Research, Scholarly and Creative Activities
• A ^ (caret) designates the author with intellectual leadership on jointly authored papers.
• A # (hash tag) identifies co-authors I mentored as undergraduate and graduate students,
postdoctoral researchers, faculty research assistants, and junior faculty.
• An * (asterisk) identifes the corresponding author.
II.A. Articles in Refereed Journals
1) Pallottoa, M, Watkins, PV, Fubaraa, B, Singer, JH, and Briggman, KL.^*
(2015) Extracellular
space preservation benefits the anatomical reconstruction of neural circuits. eLife Dec 9;4. pii:
e08206. doi: 10.7554/eLife.08206.
2) Demb, JB^*
and Singer, JH^*
(2015) Functional circuitry of the retina. Annu Rev Vis Sci Vol. 1:
263–289.
3) Firl, A, Ke, J-B,#
Zhang, L,#
Singer, JH,^*
and Feller, MB.^*
(2015) Elucidating the role of AII
amacrine cells in glutamatergic retinal waves. Journal of Neuroscience 35(4): 1675-1686
4) Stafford, BK, Manookin, MB, Singer, JH, and Demb, JB^* (2014) NMDA and AMPA
receptors contribute similarly to temporal processing in mammalian retinal ganglion cells.
Journal of Physiology 592(22): 4877–4889.
2. 5) Choi, H,#
Zhang, L,#
Cembrowski, MS,#
Sabottke, CF, Markowitz, AL,#
Butts, DA, Kath, WL,
Singer, JH^*, and Riecke, H^* (2014) Intrinsic Bursting of AII Amacrine Cells Underlies
Oscillations in the rd1 Mouse Retina. Journal of Neurophysiology 112(6): 1491-1504
6) Mehta, M, Ke, J-B,#
Zhang, L,#
Baden, A,#
Markowitz, AL, #
Nayak, S,#
Briggman, KL,
Zenisek, DP,^
and Singer, JH^* (2014) Global Ca2+
signaling drives ribbon-independent
synaptic transmission at rod bipolar cell synapses. Journal of Neuroscience 34(18): 6233–
6244.
7) Margolis, DJ^
, Gartland, AJ, Singer, JH, and Detwiler, PB^*
(2014) Network oscillations drive
correlated spiking of ON and OFF ganglion cells in the rd1 mouse model of retinal
degeneration. PLoS One 9(1): 1-12.
8) Ke, J,#
Wang, YB, Borguis, BG, Cembrowski, MS,#
Kath, WL, Riecke, H, Demb, JB,^* and
Singer, JH^* (2014) Adaptation to background light enables contrast coding at rod bipolar cell
synapses. Neuron 81(2): 388-401.
9) Cembrowski, MS,^#
Logan, SM,#
Tian, M,#
Jia, L, Li, W, Kath, WL,^
Riecke, H,^
and Singer,
JH^*
(2012) The mechanisms of repetitive spike generation in an axonless retinal interneuron.
Cell Reports 1: 155-66.
10) Demb, JB^* and Singer JH^* (2012) Intrinsic properties and functional circuitry of the AII
amacrine cell. Visual Neuroscience 29: 51-60. (invited, peer-reviewed review article)
11) Jarsky, T,#
Cembrowski M,#
Logan SM,#
Kath WL, Riecke H, Demb JB and Singer JH^*
(2011) A synaptic mechanism for retinal adaptation to luminance and contrast. Journal of
Neuroscience 31(30): 11003-11015.
12) Jarsky, T,#
Tian, M#
and Singer JH^*
(2010) Nanodomain control of exocytosis is responsible
for the signaling capability of a retinal ribbon synapse. Journal of Neuroscience 30(36): 11885-
95. (Cited twice by Faculty of 1000.)
13) Tian, M,#
Jarsky, T,#
Murphy, G, Rieke, F, and Singer, JH^*
(2010) Voltage-gated Na channels
in AII amacrine cells accelerate scotopic light responses mediated by the rod bipolar cell
pathway. Journal of Neuroscience 30: 4650-59.
14) Singer, JH,^*
Glowatzki, E, Moser, T, Strowbridge, B, Bhandawat, V, and Sampath, AP^*
(2009) Functional Properties of Synaptic Transmission in Primary Sense Organs. Journal of
Neuroscience 29(41): 12802-6. (invited, peer-reviewed review article)
15) Zhao, Y, Inayat, S, Dikin, DA, Singer, JH, Ruoff, RS, & Troy, JB^*
(2009) Patch clamp
technique: review of the current state of the art and potential contributions from
nanoengineering. Journal of Nanoengineering and Nanosystems 222(1): 1-11. (peer-reviewed
review article)
16) Fuerst, PG,^
Bruce, F, Tian, M, Wei, W, Elstrott, J, Feller, MB, Erskine, L, Singer, JH, and
Burgess, RW^*
(2009) DSCAM and DSCAML1 Function in Self-Avoidance in Multiple Cell
Types in the Developing Mouse Retina. Neuron 64: 484-97. (Cited by Faculty of 1000.)
17) Singer, JH^*
(2007) Multivesicular release and saturation of glutamatergic signaling at retinal
ribbon synapses. Journal of Physiology 580(1): 23-29. (peer-reviewed review article)
18) Chavez, A, Singer, JH^
, & Diamond, JS^*
(2006) Fast neurotransmitter release triggered by
Ca2+
influx through AMPA receptors. Nature 443(12): 705-709. (Experiments were performed
in Singer Lab at Northwestern.)
19) Singer, JH^*
& Diamond, JS^
(2006) Vesicle depletion and synaptic depression at a
mammalian ribbon synapse. Journal of Neurophysiology 95: 3191-3198.
20) Singer, JH,^*
Lassova, L, Vardi, N, & Diamond, JS*
(2004) Coordinated multivesicular release
at a mammalian ribbon synapse. Nature Neuroscience 7(8): 826-33.
3. 21) Singer, JH^*
& Diamond, JS^
(2003) Sustained Ca2+
entry elicits transient postsynaptic
currents at a retinal ribbon synapse. Journal of Neuroscience 23(34): 10923-10933.
22) Singer, JH,^*
Mirotznik, RR, & Feller, MB^
(2001) Potentiation of L-type calcium channels
reveals non-synaptic mechanisms that correlate spontaneous activity in the developing
mammalian retina. Journal of Neuroscience 21(21): 8514-8522.
23) Singer, JH & Berger, AJ^*
(2000) Development of inhibitory synaptic transmission to
motoneurons. Brain Research Bulletin 53(5): 553-560. (invited, peer reviewed review article)
24) Bansal, A, Singer, JH, Hwang, B, Xu, W, Beaudet, A & Feller, MB^*
(2000) Mice lacking
specific nAChR subunits exhibit dramatically altered spontaneous activity patterns and reveal a
limited role for retinal waves in forming circuits in the inner retina. Journal of Neuroscience
20(20): 7672-7681.
25) Singer, JH^*
& Berger, AJ^
(1999) Contribution of single-channel properties to the amplitude
variance and time course of quantal glycine currents recorded in rat motoneurons. Journal of
Neurophysiology 81: 1608-1616.
26) Singer, JH,^*
Talley, EM, Bayliss, DA, & Berger, AJ^
(1998) Development of glycinergic
synaptic transmission to rat brainstem motoneurons Journal of Neurophysiology 80(5): 2608-
2620.
27) Singer, JH,^*
Bellingham, MC, & Berger, AJ^
(1996) Presynaptic inhibition of glutamatergic
synaptic transmission to rat motoneurons by serotonin. Journal of Neurophysiology 76(2): 799-
807.
28) Jackson, DC,^*
Shi, H, Singer, JH, Hamm, PH, & Lawler, RG^*
(1995) Effects of input
pressure on in vitro turtle heart during anoxia and acidosis: a 31P-NMR study. American
Journal of Physiology 268: R683-89.
29) Jackson, DC,^*
Singer, JH, & Downey, P (1991) The oxidative cost of ventilation in the
Western painted turtle, Chrysemys picta bellii. American Journal of Physiology 261: R1325-28.
II.B. Published Conference Proceedings
1) Singer, JH2,4
& Berger, AJ3
(1996) Presynaptic inhibition by serotonin: A possible mechanism
for switching motor output of the hypoglossal nucleus. Sleep 19(10): S146-49.
II.C. Conferences, Workshops, and Talks
II.C.1. Keynotes
1) RSS 2013 Ribbon Synapses Symposium, Gottingen, Germany (October 2013): “Retinal ribbon
synapses” (Keynote address)
II.C.2. Invited Talks
1) National Institutes of Health, National Eye Institute Intramural Research Program (August
2015): “From synapse to circuit: studies of retinal function.”
2) University of Washington, Department of Biological Structure and Vision Training Grant (May
2015): “From synapse to circuit: studies of retinal function.”
3) University of Louisville, Department of Ophthalmology & Visual Sciences (April 2015):
“From synapse to circuit: studies of retinal function.”
4) Allen Institute for Brain Science (August 2013): “Synaptic dynamics determine retinal circuit
function”
5) University of Idaho, Department of Biology (August 2013): “Synaptic dynamics determine
retinal circuit function”
4. 6) University of Pennsylvania, Vision Colloquium (April 2013): “Synaptic dynamics determine
retinal circuit function”
7) Max Planck Institute for Experimental Medicine, Gottingen, Germany (November 2012):
“Relating synaptic dynamics to circuit function”
8) University of Maryland, Department of Physiology, Baltimore, MD (September 2012):
“Quantitative analysis of transmission from rod bipolar cells.”
9) Johns Hopkins University, Center for Hearing and Balance, Baltimore, MD (September 2012):
“Analyses of synaptic transmission at a retinal ribbon synapse.”
10) Yale University Department of Cellular and Molecular Physiology, New Haven, CT (April
2012): “Synaptic mechanisms underlying circuit function in the mammalian retina.”
11) Vollum Institute, Oregon Health Sciences University, Portland, OR (December 2011):
“Synaptic mechanisms underlying circuit function in the mammalian retina.”
12) University of Illinois, Chicago, Department of Ophthalmology, Chicago, IL (September, 2011)
“Synaptic transmission at rod bipolar cell synapses.”
13) University of Zurich, Brain Research Institute, Zurich, Switzerland (March 2011): “The
synaptic mechanism for sensory gain control at a retinal synapse.”
14) University of Virginia, Department of Pharmacology, Charlottesville, VA (March 2011):
"Synaptic mechanisms underlying gain control in the retinal circuitry"
15) Jefferson Medical College, Department of Neuroscience, Philadelphia, PA (February 2011):
"Synaptic mechanisms underlying gain control in the retinal circuitry"
16) University of Maryland, Department of Biology, College Park, MD (February 2011): "Synaptic
mechanisms underlying circuit function in the retina"
17) University of Colorado, Department of Physiology and Biophysics, Denver CO (February
2011): "Synaptic mechanisms underlying circuit function in the retina"
18) University of Washington, Dept. Physiology and Biophysics, Seattle, WA (March 2010): “One
channel, one vesicle; two channels, two vesicles: synaptic transmission at an analog synapse in
the mammalian retina”
19) Brown University, Dept. Molecular Pharmacology, Physiology, and Biotechnology,
Providence, RI (October 2006): “Understanding the dynamics of transmission at a mammalian
retinal ribbon synapse.”
20) University of Illinois, Chicago, Department of Anatomy and Cell Biology, Chicago, IL (May
2006): “Factors influencing the dynamics of synaptic transmission at rod bipolar cell ribbon
synapses.”
21) Northwestern University, Dept. Ophthalmology (June 2004): “The dynamics of synaptic
transmission at mammalian rod bipolar cell ribbon synapses.”
22) University of Puerto Rico, Institute for Neurobiology (March 2004): “The dynamics of synaptic
transmission at a mammalian ribbon synapse.”
23) University of Chicago, Dept. Anesthesiology (January 2004): “The dynamics of synaptic
transmission at a mammalian ribbon synapse.”
24) University of Washington, Dept. Physiology and Biophysics (January 2002): “Synaptic
transmission from retinal rod bipolar cell ribbon synapses.”
25) Brown University, Dept. Molecular Pharmacology, Physiology, and Biotechnology (November
1998): “Contribution of glycine channel properties to the time course and amplitude variance of
inhibitory synaptic transmission in the developing brainstem.”
26) University of Tennessee, Dept. Anatomy and Neurobiology (October 1997): “Glycinergic
synaptic transmission to developing brainstem motoneurons.”
5. II.C.3. Refereed Presentations
1) RSS 2011 Ribbon Synapses Symposium, Gottingen, Germany (September 2011): “Quantitative
analyses of synaptic gain at the rod bipolar ribbon synapse.”
2) Winter Neuroscience Conference, Solden Austria (March 2011): “The synaptic mechanism for
3) Calcium Signals in Sensory Processing Symposium, Gottingen, Germany (May 2010): “One
channel, one vesicle; two channels, two vesicles: transmission at an analog ribbon synapse”
4) RSS 2009 Ribbon Synapses Symposium, Gottingen, Germany (May 2009): “Ca2+
-exocytosis
coupling at a mammalian retinal ribbon syanpse.”
5) FASEB Summer Research Conference, Snowmass Village, CO (July 2008): “AII amacrine
cells are high-fidelity relays of rod bipolar cells’ output.”
6) Winter Conference on Brain Research, Snowbird, UT (January, 2008): “Dendritic integration in
AII amacrine cells.”
7) ARVO Minisymposium: “Ins and Outs of the Retinal Signal Through Bipolar Cells” Ft.
Lauderdale, FL (May 2007): “Neurotransmitter release at the bipolar cell terminal.”
8) RSS 2005 Ribbon Synapses Symposium, Gottingen, Germany (September 2005):
“Multivesicular release and synaptic depression at a retinal ribbon synapse.”
9) Winter Conference on Brain Research (January 2005): “Multivesicular release and synaptic
depression at mammalian rod bipolar cell synapses.”
10) Winter Conference on Neural Plasticity, St. Lucia, West Indies (February 2004):
“Multivestcular release and synaptic depression at rod bipolar cell synapses.”
11) FASEB Summer Research Conference, Saxton’s River, VT (July 2002): “Kinetics of synaptic
transmission at mammalian rod bipolar cell synapses.”
II.C.4. Refereed Abstracts
1) Shi, H, Memarzadeh, S, Singer, JH, & Butts, DA. (2016) Robust extraction of the diversity of
ganglion cell computation via spatially correlated stimuli and nonlinear modeling. ARVO.
2) Singer, JH, Mortensen, LS, Park, SJ, Ke, J-b, Zhang, L, Brose, N, Rhee, J-S, Demb, JB. (2016)
The absence of complexin 3 alters rod bipolar cell pathway function. ARVO.
3) Shi, H., Sabotke, CF, Butts, DA, Carleton, K, and Singer, JH. (2015) Physiological
Characterization of Retinal Ganglion Cell Types in Tilapia mariae. ARVO.
4) Mortensen, LS, Reim, K, Ke, J-B, Brose, N, Singer, JH, & Rhee, J-S (2014) Complexin 3
regulates vesicle release at a mammalian ribbon synapse. Society for Neuroscience.
5) Ke, J-B, Mortensen, LS, Reim, K, Rhee, J-S, Brose, N, & Singer, JH (2014) Control of a slow
phase of synaptic transmission at a retinal ribbon synapse. Society for Neuroscience.
6) Singer, JH, Ke, J-B, Mehta, B, Baden, A, Markowitz, AL, Nayak, S, Briggman, KL, Zensiek,
D (2014) Global Ca2+
signaling drives ribbon-independent synaptic transmission at rod bipolar
cell synapses. FASEB, Retinal Neurobiology and Visual Processing.
7) Ke, J, Mehta, B, Baden, A, Markowitz, A, Nayak, S, Briggman, KL, Zensiek, D, & Singer, JH
(2013) Ectopic release at a mammalian ribbon synapse reflects a transition from local to global
control of exocytosis by presynaptic Ca channels. Society for Neuroscience.
8) Choi, H, Cembrowski, MS, Singer, JH, Kath, WL, & Riecke, H (2013) Intrinsically bursting
AII amacrine cells drive oscillations in wildtype and rd1 retina. Society for Neuroscience.
9) Riecke, H, Choi, H, Cembrowski, MS, Kath, WL, & Singer, JH (2013) Spikelets and bursts in
axonless retinal AII amacrine cells coupled by gap junctions. Organization for Computational
Neurosciences.
6. 10) Riecke, H, Choi, H, Cembrowski, MS, Kath, WL, & Singer, JH (2013) Spiking and bursting in
gap-juction coupled axonless retinal amacrine cells. The 8th IMACS International Conference
on Nonlinear Evolution Equations and Wave Phenomena: Computation and Theory.
11) Ke, J, Wang, Y, Cembrowski, MS, W, Kath, WL, Riecke, H, Demb, J. & Singer, JH (2013)
Adaptation to background light permits contrast coding at rod bipolar cell synapses. ARVO.
12) Ke, J, Cembrowski, MS, Wang, Y, Riecke, H, Kath, WL, Demb, JB, & Singer, JH (2012)
Assessing the operating range of the rod bipolar cell. Society for Neuroscience.
13) Ke, J, Cembrowski, MS, Wang, Y, Riecke, H, Kath, WL, Demb, JB, & Singer, JH (2012)
Assessing the operating range of the rod bipolar cell. FASEB, Retinal Neurobiology and
Visual Processing.
14) Cembrowski, MS, Logan, S, Tian, M, Jia, L, Li, W, Kath, WL, Riecke, H, & Singer, JH
(2012) The mechanisms of repetitive spike generation in an axonless retinal interneuron. The
FASEB, Retinal Neurobiology and Visual Processing.
15) Cembrowski, MS, Logan, S, Tian, M, Jia, L, Li, W, Kath, WL, Riecke, H, & Singer, JH
(2012) The mechanisms of repetitive spike generation in an axonless retinal interneuron. The
Organization for Computational Neurosciences: 60 Years of Hodgkin and Huxley Meeting.
16) Singer, JH, Cembrowski, MS, Logan, S, Demb, JB, & Jarsky, T (2011) Gain control at rod
bipolar cell synapses is driven primarily by vesicle depletion. ARVO.
17) Cembrowski, MS, Riecke, H, Kath, WL, & Singer, JH (2011) An axonless neuron with axon-
like firing: the AII amacrine interneuron of the mammalian retina. Computational and Systems
Neuroscience.
18) Jarsky, T, Cembrowski, MS, Logan, S, Dunn, F, Demb, J, & Singer, JH (2010) Signal transfer
at a mammalian ribbon synapse. Society for Neuroscience.
19) Cembrowski, MS, Riecke, H, Kath, WL, & Singer, JH (2010) Burst firing in the AII amacrine
interneuron of the mammalian retina. Society for Neuroscience.
20) Jarsky, T, Cembrowski, MS, Demb, JB, & Singer, JH (2010) Signal transfer at a retinal ribbon
synapse. FASEB, Retinal Neurobiology and Visual Processing.
21) Fuerst, PG, Erskine, L., Singer, JH, & Burgess, RW (2009) The where and when of Dscam-
mediated retinal and brain organization. Society for Neuroscience.
22) Jarsky, T. & Singer, JH (2009) Ca2+
-exocytosis coupling at a mammalian ribbon synapse.
Society for Neuroscience.
23) Cembrowski, M., Tian, M., Kath W., Riecke, H. & Singer, JH (2009) Signal transfer through
the AII amacrine cell network to the origins of ON and OFF streams in the mammalian retina.
Society for Neuroscience.
24) Tian, M. & Singer, JH (2008) High-fidelity signal transfer between AII amacrine cells and
cone bipolar cells in the mammalian retina Society for Neuroscience.
25) Jarsky, T. & Singer, JH (2008) A linear relationship between Ca2+
entry and exocytosis at a
mammalian ribbon synapse. Society for Neuroscience.
26) Tian, M. & Singer, JH (2007) A high-voltage activated A-type potassium conductance
attenuates postsynaptic responses to excitatory synaptic inputs at a retinal ribbon synapse.
Society for Neuroscience.
27) Singer, JH (2006) A-type potassium currents in mammalian AII amacrine cells. ARVO.
28) Singer, JH & Diamond, JS (2004) Vesicle depletion underlies short-term depression at a
mammalian ribbon synapse. Society for Neuroscience.
29) Singer, JH & Diamond, JS. (2004) Multivesicular release and short-term depression at rod
bipolar cell synapses. FASEB, Retinal Neurobiology and Visual Processing.
7. 30) Singer, JH, Chavez, A., & Diamond, JS (2003) Physiological evidence for peri- or extra-
synaptic GABAC receptors on mammalian rod bipolar cell terminals. Society for Neuroscience.
31) Singer, JH & Diamond, JS (2003) Multivesicular release from mammalian rod bipolar cells.
ARVO.
32) Singer, JH & Diamond, JS (2002) Kinetics of transmitter release and short term depression at a
mammalian ribbon synapse. Society for Neuroscience.
33) Singer, JH & Diamond, JS (2001) Synchronous and asynchronous neurotransmitter release at a
mammalian ribbon synapse. Society for Neuroscience.
34) Singer, JH, Mirotznick, R, & Feller, MB (2000) Modulation of L-type calcium channels
dramatically alters the propagation of neural activity in the developing mammalian retina.
Society for Neuroscience.
35) Singer, JH, Mirotznick, R, & Feller, MB (2000) Inter-cellular coupling via gap junctions may
propagate retinal waves in the absence of fast synaptic transmission. FASEB, Retinal
Neurobiology and Visual Processing.
36) Singer, JH & Feller, MB. (2000) Modulation of L-type calcium channels alters the propagation
of correlated activity in the developing mouse retina. IVOS 41(4): S935.
37) Singer, JH & Berger, AJ (1998) Development of glycinergic synaptic transmission to rat
brainstem motoneurons. Society for Neuroscience.
38) Singer, JH, Isaacson, JS, Talley, EM, Bayliss, DA, & Berger, AJ (1997) Receptor-subunit
composition and channel kinetics govern the time course of glycinergic synaptic transmission
in the developing brainstem. Society for Neuroscience.
39) Berger, AJ, Singer, JH, & Isaacson, JS (1997) Biophysical properties of glycine receptors in
rat hypoglossal motoneurons. Society for Neuroscience.
40) Singer, JH, Bellingham, MC, & Berger, AJ (1996) Developmental changes in NMDA-
receptor-mediated synaptic transmission to rat motoneurons. Society for Neuroscience.
41) Singer, JH, Bellingham, MC, & Berger, AJ (1996) Presynaptic inhibition of glutamatergic
synaptict ransmission to rat motoneurons by serotonin. The Physiologist 39(3): 169.
42) Singer, JH, Bellingham, MC, & Berger, AJ (1996) Presynaptic inhibition of glutamatergic
synaptic transmission to rat motoneurons by serotonin. 4th International Symposium on Sleep
& Respiration.
43) Jackson, DC, Shi, H, & Singer, JH (1994) Mechanical responses of isolated turtle hearts to
variations in preload during anoxia and acidosis. Experimental Biology (FASEB).
II.E.5. Refereed Panels
1) Chicago Chapter of the Society for Neuroscience, Chicago, IL (March 2009): “Visual
neuroscience: from retina to behavior.” Organizer and program chair
II.E.6. Symposia
1) Society for Neuroscience Minisymposium (co-organizer): Functional Properties of Synaptic
Transmission in Primary Sensory Organs, Chicago IL (October 2009): “Ca2+
-exocytosis coupling
at mammalian rod bipolar cell synapses.”
II.F. Book Reviews, Notes, and Other Contributions
II.F. 1. Book Reviews
1) Singer, JH3,4
(2006) Sensation and Perception. Survey of Ophthalmology 51(3): 286. (book
review)
8. II.F. 2. Essays
1) Singer, JH3,4
(2008) GABA is an endogenous agonist of glycine receptors. Neuron 57(4): 475-
77. (invited “news and views”)
II.G. Sponsored Research
II.G.1. Grants
i) Ongoing Research Support
1) NIH RO1 EY-017836-9: Synaptic transmission in the rod pathway of the mammalian retina. PI:
Joshua H. Singer; Dates: XXXXX; Total Direct Costs: XXXXX; renewal of RO1 EY-017836-8
2) NIH RO1 EY-021372-4: Computation at retinal synapses. PI: Joshua H. Singer; Co-PI: Jonathan
B. Demb; Dates of support: 8/01/14-7/31/17. Total Direct Costs: $833,000; renewal of RO1 EY-
021372-3
ii) Completed Research Support
1) NIH RO1 EY-017836-8: Synaptic transmission in the rod pathway of the mammalian retina. PI:
Joshua H. Singer; Dates: 5/01/12-4/31/15; Total Direct Costs: $600,000; renewal of RO1 EY-
017836-5
2) NIH NS-43365 (K22 Career Development Award): Synaptic transmission in the mammalian
inner retina. PI: Joshua H. Singer; Dates: 1/06/05-3/31/07; Total Direct Costs: $350,000
3) Midwest Eye Banks Research Grant: PI: Joshua H. Singer; Dates: 8/01/07-7/31/08; Total Direct
Costs: $15,000
4) NSF DBI-0551852: Nanoengineered enhancements to the patch-clamp technique. PI: John Troy,
Co-PI: Joshua H. Singer; Dates: 9/1/06-8/31/09; Total Direct Costs: $621,043
5) Alfred P. Sloan Foundation Research Fellowship: PI: Joshua H. Singer; Dates: 9/01/07-8/31/09;
Total Direct Costs: $45,000
6) RPB Special Scholar Award: Neural function in a retinal network in a mouse model of RP. PI:
Joshua H. Singer; Dates: 6/15/11-6/14/12; Total Direct Costs: $75,000
7) NIH R01 EY-017836-5: Synaptic transmission in the rod pathway of the mammalian retina. PI:
Joshua H. Singer; Dates: 4/01/07-3/31/12; Total Direct Costs: $1,125,000
8) NIH RO1 EY-021372-3: CRCNS: Biophysical properties of parallel neural circuits serving night
vision. PI: Joshua H. Singer; Dates: 9/01/10-8/31/14; Total Direct Costs: $727,000
II.H. Fellowships, Gifts and Other Funded Research
II.H.1. Fellowships
2011: Research to Prevent Blindness Special Scholar Award for Retinitis Pigmentosa
2008: Kavli Foundation Frontiers of Science Symposium Fellowship
2007-2009: Alfred P. Sloan Foundation Research Fellowship
2000: Fellows’ Award for Research Excellence (NIH)
1999-2001: Pharmacology Research Associate Training Program Fellowship (NIGMS)
II.H.2. Other
2002-2007: NINDS Career Development (K-22) Award
9. II.I. Submissions and Works in Progress
II.I.1. Current Grant Applications
II.L.2. Manuscripts in Preparation
1) Li, G-L2
, Zhang, H, Singer, JH, and von Gersdorff H.^*
Cooperative release of synaptic vesicles
at an auditory hair cell ribbon synapse.
II.I.3. Manuscripts under Review (indicate status: submitted or revising to resubmit)
III. Teaching, Mentoring and Advising.
III.A. Courses Taught
a) COURSES TAUGHT IN THE LAST FIVE YEARS
At the University of Maryland
Dates Course (number of students, leadership positions)
2015 Fundamentals of Sensory Processing (20, Univ. of Gottingen, lecturer)
2015 Fall BSCI440: Mammalian Physiology (170, sole lecturer, organizer)
2015 Fall BSCI339G: Advanced Physiology (19, sole lecturer, organizer)
2015 Spring BSCI339G: Advanced Physiology (17, sole lecturer, organizer)
2014 Fall BSCI440: Mammalian Physiology (150, sole lecturer, organizer)
2014 Fall BSCI279: Readings in physiology (2, leader and organizer)
2014 Spring BSCI279: Readings in physiology (6, leader and organizer)
2014 Spring BSCI338N: Neurobiology of Disease (48, sole lecturer, organizer)
2013 Fundamentals of Sensory Processing (20, Univ. of Gottingen, lecturer)
2013 Fall BSCI440: Mammalian Physiology (152, sole lecturer, organizer)
2013 Fall BSCI279: Readings in physiology (10, leader and organizer)
2013 Spring BSCI279: Readings in physiology (1, leader and organizer)
2013 Spring BSCI338N: Neurobiology of Disease (48, sole lecturer, organizer)
2012 Fall BSCI440: Mammalian Physiology (130, sole lecturer, organizer)
2012 Spring BSCI338N: Neurobiology of Disease (35, lecturer)
At Northwestern University
Dates Course (number of students, leadership positions)
2010 Fundamentals of Sensory Processing (20, Univ. of Gottingen, lecturer)
2009-2011 NUIN 495: Sensory Neurobiology (5, course developer and director)
2008 NUIN 411: Great Experiments (5, conference leader)
2006-2008 NUIN 401: Fund. of Neuro. (50 / year, lecturer and course director)
2007-2011 Problem-based learning 103, 202 (10 / year, conference leader)
III.B. Teaching Innovations
BSCI440: Integrated problem-based learning from case studies into the curriculum, introduced
novel group assignments, began use of undergraduate TAs and dedicated instructional assistants to
increase instructor-student ratio in discussion section.
BSCI339G: Developed an upper-level physiology course to follow BSCI440.
10. III.C. Advising: Research or Clinical
III.C.1. Undergraduate
John Athey 2014
Jacqueline Arguello 2013-14
Anthony Ayala 2012- Louis Stokes Alliance Fellowship; HHMI
ExROP Fellowship; Biology Honors Program
Alexander Baden 2012-14 Graduated, now in Computer Science PhD
program at Johns Hopkins
Tyler Chafitz 2015- Biology Honors Program
Shima Ge 2012-13
Ari Goldstein 2014
Padideh Ghorbani 2013-15 Graduated in 2014
Christopher Hahn 2013 Graduated
Austin Hankinson 2013 Graduated
Adam Heilmann 2013-14 Graduated
Steven Kurapaty 2014- Biology Honors Program
Evan Lieberman 2014- Biology Honors Program
Alexander Lin 2015-
Sayi Lindeire 2012-13 Louis Stokes Alliance Fellowship
Joseph Masison 2013-
Alexander Markowitz 2012-14 Graduated, in Neuroscience PhD program
at USC
Allie Merrihew 2012-14 Graduated
Subhashree Nayak 2012-14 HHMI Undergraduate Research Fellowship
Vu Nguyen 2015
Andrew Nesdill 2013-14 Graduated
Stephan Olaya 2015-
Gautam Rao 2012-14 Graduated
Narrwe Park 2013 Graduated
Olivia Payne 2015
Abhrarup Roy 2014- Biology Honors Program
Anika Sikder 2014-
Keenan Sobol 2015-
Kevin Sistani 2012-14 Graduated
Joseph Varialle 2014
Michelle Yi 2013 Graduated
III.C.2. Doctoral
Gregory Perrin 2015-
Mark Cembrowski 2008-2011 Postdoctoral at Janelia Farms
(Predoctoral NSF Fellowship)
Hannah Choi 2010-2014 Postdoctoral at SUNY Downstate
11. III.C.3. Post-doctoral
Tim Jarsky, PhD 2007-12 Scientist II at Allen Institute
(Postdoctoral NRSA)
Jiangbin Ke, PhD 2010- To take position as Full Professor at
Sun-Yat Sen University in
Guangzhou, China in Spring 2016
Dihui Lai 2012 Actuary in insurance industry
Stephen M. Logan, PhD 2009-11 Asst. res. prof.; Northwestern
Lena S. Mortensen, PhD 2013- co-mentor: Nils Brose at MPI
Gottingen
Miao Tian, MD, PhD 2006-9 Practicing physician
Qing (Hope) Shi 2014-
Manisha Sirivastava, PhD 2010-11
Lei Zhang 2013-
III.E. Advising: Other than Research Direction
III.E.1. Doctoral
At the University of Maryland
2015 Thesis committee: Yuwei Cui (Neuroscience and Cognitive Science)
2013- Thesis committee: Krystina Orzechowski (Neuroscience and Cognitive
Science)
At Northwestern University
2005-11 Thesis committees: Mark Benton, Michael Johnson, & Tereza Smejkalova (Integrated
Neuroscience), Tracy Gertler & Adam Light (Medical Scientist Training Program),
Samsoon Inayat & Yan Zhao (Biomedical Engineering)
IV. Service and Outreach
IV.A. Editorships, Editorial Boards, and Reviewing Activities
IV.A.1. Editorial Boards
Associate editor, Journal of Neuroscience (2011- )
Associate Editor, Frontiers in Neural Circuits (2015- )
IV.A.2. Reviewing Activities for Journals and Presses
Current Biology, eLife, Journal of Neuroscience (Acknowledgement for Frequent Review 2010-
2014), Journal of Neurophysiology, Journal of Physiology, Molecular and Cellular
Neuroscience, Molecular Vision, Nature Neuroscience, Neuron, Neuroscience, PLoS One
IV.A.3. Reviewing Activities for Agencies and Foundations
Study Sections: Collaborative research in computational neuroscience (joint NSF-NIH; February
2011), Synapses, Cytoskeleton and Trafficking (NIH; March 2014; mail reviewer),
Neurotransporters, Receptors, Channels and Calcium Signaling (NIH; July 2014)
Ad hoc grant review: Biotechnology and Biological Sciences Research Council (United Kingdom),
Israel Science Foundation, Nebraska Experimental Program to Stimulate Competitive Research,
Human Frontiers Science Program, Canadian Institutes of Health Research, Health Research
Council of New Zealand, U.S. Civilian Research and Development Foundation, National Science
Foundation
12. IV.B. Committees, Professional & Campus Service
IV.B.1. Campus Service – Department
2015-16 Faculty Search (Biology)
2014 Review of Workload Equitability (Biology)
2014 Assistant Investigator Search (Biology)
2013- Faculty Advisory Committee, Chair 2014-15 (Biology)
2013- Undergraduate Policy, Courses, and Curriculum (Biology)
2012-13 Annual Departmental Retreat, Planning and Post-Retreat Advising (Biology)
2012-13 Faculty Search (Biology)
2012 Lecturer Search (Biology)
IV.B.2. Campus Service – College
2015 Dorfman Prize Review Committee
IV.B.3. Campus Service – University
2015 University representative at ABRCMS Meeting (Seattle, November 2015)
2015- Department of Biology representative to University Senate
2015 Selection committee for Banneker/Key Scholarship
2014 Advisor to GEMSTONE Team (Team BLAST)
2013- Executive committee (Neuroscience and Cognitive Science)
2012- Seminar Series (Neuroscience and Cognitive Science)
2012- Graduate Admissions Committee (Neuroscience and Cognitive Science)
IV.B.4. Leadership Roles in Meetings and Conferences
1) Meeting co-organizer and co-chair (with T. Moser, D. Zenisek, F. Schmitz, and L.
Mortensen): Ribbon Synapse Symposium 2015, Max Planck Institute for
Experimental Medicine and University of Gottingen, Germany (2015)
2) Meeting co-organizer and co-chair (with T. Moser, H. von Gersdorff, and H.
Brandstatter): Ribbon Synapse Symposium 2013, Max Planck Institute for
Experimental Medicine and University of Gottingen, Germany (2013)
3) Symposium co-organizer and co-chair (with AP Sampath, USC): “Functional
Properties of Synaptic Transmission in Primary Sensory Organs,” Society for
Neuroscience Annual Meeting (2009)
4) Symposium organizer and chair: “Visual Neuroscience: From Retina to Behavior,”
Chicago Chapter of the Society for Neuroscience Annual Meeting, Chicago, IL
(2009)
IV.B.5. Other Non-University Committees, Memberships, Panels, etc.
Professional societies:
Member: Society for Neuroscience (1996-present)
Member: Association for Research in Vision and Ophthalmology (ARVO, 1999-present)
Councilor: Chicago Chapter of the Society for Neuroscience (2008-2010)
IV.B.9. Other
2014 External referee for a tenure and promotion case, University of Göttingen, Germany
2010 Faculty Search, Dept. Physiology (School of Medicine, NWU)
2006-09 NUIN Admissions (Graduate School; Chair from 2007-2009, NWU)
2006-07 NUIN Retreat (Graduate School; Chair in 2007, NWU)
2007-09 NUIN Curriculum (Graduate School, NWU)
13. IV.C Community & Other Service
Community
2014: AAAS Speaker, USA Science & Engineering Festival "What Optical Illusions Tell Us about
the Eyes and Brain"
V. Awards, Honors and Recognition
V.1. Research Fellowships, Prizes and Awards
2011: Research to Prevent Blindness Special Scholar Award for Retinitis Pigmentosa
2008: Kavli Foundation Frontiers of Science Symposium Fellowship
2007-2009: Alfred P. Sloan Foundation Research Fellowship
2000: Fellows’ Award for Research Excellence (NIH)
1999-2001: Pharmacology Research Associate Training Program Fellowship (NIGMS)
2002-2007: NINDS Career Development (K-22) Award