2. ONE HUNDRED YEARS OF HORMONES
In June 1905, Ernest Starling, a professor of physiology at University College London,
first used the word “hormone” in his lecture – On the chemical correlation of the
functions of the body.
In addition to purely scientific advances, the study of hormones has led to enormous
benefits to human health, social and economic progress, such as contraception, in vitro
fertilization (IVF) and recombinant human hormones.
By reconstructing a DNA sequence that existed more than 450 million years ago, Joe
Thornton, a research scientist and evolutionary biologist at Columbia’s Earth Institute,
concluded that the female hormone estrogen is the most ancient of all steroid hormones
but that its role in differentiating the sexes from each other developed much later.
The English physician E. H. Starling discovered in collaboration with the physiologist W. M.
Bayliss, Secretin, the first hormone, in 1902.
3. The normal male cock was injected with the female hormone
estrogen. In due course of time, there were remarkable
changes in the chicken.
The maleness character reduced and brought in femaleness.
--Concise Biology H.S.Vishnoi
4. Among invertebrates, evidence of hormone control is less satisfactory in the
acoelomate and pseudocoelomate animals. However, studies of endocrine function of
the coelomate vertebrates have been mainly confined to the arthropods, annelids,
molluscans and echinoderms; the arthropods (esp., the insects and crustaceans) are
the best-studied group.
1. Hormones from Coelenterata
The neurosecretory growth hormone, as it may be called, is credited with
the following two functions :
(a) It activates cell proliferation.
(b) It causes interstitial cells to develop into somatic structures such as
nematocysts. In the absence of this hormone, growth ceases and
interstitial cells form gametes.
2. Hormones from Annelida
The studies regarding regeneration of Nereis diversicolor have been
conducted by Clark et at in 1962.Segment proliferation is regulated by
hormones synthesized in the supra-oesophageal ganglia. It is,
however, not known whether the growth-promoting and the
regeneration-promoting hormones are identical (Jenkin, 1970)
5. 3. Hormones from Arthropods
A. Insecta
Among invertebrates, insects and crustaceans furnish excellent examples of
hormone secretion. These hormones govern many metabolic processes including
growth, development, reproduction, colour adaptation etc.
The processes of moulting and metamorphosis are controlled by hormones
secreted by the following three organs of endocrine nature. (a) neurosecretory
cells of corpus cardiacum (b) prothoracic gland (c) corpus allatum.
In the larva, corpus allatum secretes another hormone called status quo hormone
(SQH) or neotenin. This delays metamorphosis of immature insects by
maintaining the juvenile character of the growing insect for a longer period.
B. Hormones from Crustacea.
The hormones in crustaceans are usually produced in the neurosensory cells
of the brain and in the central nervous system. The sinus glands of these
invertebrates produce a moult-inhibiting hormone which is stored in the
sinus glands found in the eye stalks or in the head in species without eye
stalks.
The chromatophores in crustaceans contain pigments concerned with the
body colour. The relative dispersion and concentration of these pigments is
controlled by colour-change hormones.
6. 5. Hormones from Echinodermata
.
According to Chaet (1967), in the starfishes, a simple
system of hormones regulates sexual maturation and
spawning. Two such hormones recognized are : (a) gonad-
stimulating substance (GSS)—It is a low molecular weight
(2,000) protein which is synthesized in the radial nerves.
(b) maturation-inducing substance (MIS) and is produced
by the ovarian follicles.
4. Hormones from Mollusca
Molluscans have a sophisticated endocrine system because
they have glands that secrete hormones and a circulatory
system that transmits the hormones to the certain organ.
The optic glands dominate the reproductive endocrinology in a
manner somewhat comparable to the vertebrate pituitary.
The optic glands are small areas, near the brain, that control
body growth, gonadal maturation, and parts of the central
nervous system. Octopuses also secrete a hormone, in the
nervous system, that controls water balance. The cerebral
ganglion, in snails, secretes a neurohormone that controls the
development of both parts of the snail. An experiment was
done with a chemical called trebutyltin.
--Hormone Biochemistry : Animal Hormones
7.
8. In human fetal life, this area produces melanocyte stimulating hormone or MSH
which causes the release of melanin pigment in skin melanocytes (pigment cells).
In lower vertebrates (fish, amphibians) MSH from the pars intermedia is
responsible for darkening of the skin, often in response to changes in background
color. This color change is due to MSH stimulating the dispersion of melanin
pigment in dermal (skin) melanophore cells.
https://www.healthline.com/human-body-maps/pituitary-gland#diagram
Pituitary gland
9.
10.
11. Pauline Musters (February 26, 1876 – March 1, 1895) at 24 inches (61 cm) tall, is
recognized by the Guinness Book of Records as the shortest woman ever
recorded.
Born in Netherlands and died in New York City at the age of 19 from a
combination of pneumonia and meningitis. At the time of her death, she
measured exactly 61 cm (24 in) tall.
Jyoti Kisange Amge (16 December 1993) is an Indian woman and actress
notable for being the world's smallest living woman according to Guinness
World Records.
In 2011, she was officially declared the world's smallest woman by Guinness
World Records with a height of 62.8 cm. Her restricted height is due to a
growth abnormality called primordial dwarfism.
Chandra Bahadur Dangi was the shortest man in recorded history
for whom there is irrefutable evidence, measuring 54.6 cm. Dangi
was a primordial dwarf.
Born: 30 November 1939 Died: 3 September 2015
12. Robert Pershing Wadlow (Feb 22, 1918 – Jul 15, 1940), also known
as the Giant of Illinois, was an American who became famous as
the tallest person in recorded history . He was born and raised
in Alton, Illinois.
Wadlow reached 8 ft 11.1 in (2.72 m)in height and weighed 439 lb
(199 kg) at his death at age 22. His great size and his continued
growth in adulthood were due to hyperplasia of his pituitary gland,
which results in an abnormally high level of human growth
hormone (HGH). He showed no indication of an end to his growth
even at the time of his death.
Sultan Kösen (born 10 December 1982) is a
Turkish-Kurdish farmer who holds the Guinness
World Record for tallest living male at 251 cms
(8 ft 2.82 in).His growth resulted from the
condition acromegaly, caused by a tumour
affecting his pituitary gland.His stature is such
that he uses crutches in order to walk.
15. The precursor to melatonin is serotonin, a neurotransmitter that itself is derived from the amino
acid tryptophan. Within the pineal gland, serotonin is acetylated and then methylated to
yield melatonin. Synthesis and secretion of melatonin is dramatically affected by light exposure to
the eyes.