recombinant parathyroid

1. FORTEO
TERIPARATIDE
BY:- MOHAMMAD SAMEER
BSC BT II YEAR

3. DESCRIPTION
Teriparatide (recombinant human
parathyroid hormone) is a potent
anabolic agent used in the treatment
of osteoporosis.
Teriparatide is a recombinant
protein form of parathyroid hormone.
It is also occasionally used to speed
fracture healing.
It is produced in E.Coli through
recombinant dna technology.

4. MECHANISM OF ACTION
Daily injections of teriparatide
stimulates new bone formation leading to
increased bone mineral density.
Through activation of various bone
metabolic pathways, the PTH drug
(Forteo) increases the number of active
osteoblasts (bone-building cells),
decreases the naturally programmed
death of osteoblast cells, and recruits
bone-lining cells as osteoblasts.
This drug appears to act largely upon
the bone-building osteoblast cells
stimulating them to overactivity.

5. SIDE EFFECTS
muscle cramps or spasms,
leg cramps,
joint pain,
cough,
sore throat,
runny nose,
headache,
neck pain,

6. THANK YOU