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Medical Facts of
STEM CELL THERAPY
Dr. Sharda Jain
Mr. Prabhu Mishra
DR. YOGESH AGARWALA
Dr. Rajesh Dhall
Dr. Rashmi Jain
Dr. Indu Tyagi
Ms. Himani Agnihotri
in Rheumatoid
Arthritis
Public Awareness series
WELCOME
to world of STEM CELL THERAPY
– a Medical Revolution in Rheumatoid
Arthritis to manage Day Today Life &
Halt the Disease Process
RHEUMATOID ARTHRITIS
Rheumatoid arthritis or RA is an autoimmune
condition, which primarily affects the synovium in
the knee, causing inflammation followed by
destruction of the joint surfaces.
www.globalstemgenn.com
Advance Disease Pictures
SYMPTOMS
• Initial symptoms of RA are generally pain
and morning stiffness.
• RA in the knee can be isolated or be a part of
generalized pain.
• The disease, which starts as synovitis in the
knee, progresses
to destroy the joint.
SYMPTOMS
• Classically, there would be
involvement of small joints of the
hands and feet.
SYMPTOMS contd…..
• The disease is characterized by episodes of acute
inflammation interspersed with periods of
remission.
• When the arthritis takes toll on the
cartilage of the knee, the joint
becomes deformed and painful even
to the slightest of movement.
www.globalstemgenn.com
LAB TEST
• Blood tests can be useful to make a diagnosis of
RA. Blood tests will show the presence of the
antibody called rheumatoid factor (RA test).
HOWEVER, ABSENCE OF THE ANTIBODY DOES NOT
EXCLUDE RA.
• X-RAYS IN EARLY RA CAN BE NORMAL, as the
involvement would limit to the synovium.
• Over a long period of time, X-rays will reveal
destruction of joint margins, deformity, bone loss
and severe osteoporosis.
www.globalstemgenn.com
Please remember
• It is Bad and Progressive
disease, that leaves you
incapable to do anything
if you don’t take timely
action.
MANAGEMENT AND TREATMENT
•It is now universally
acceptable that there is
NO complete cure for RA.
TREATMENT IS MAINLY SUPPORTIVE
- Treatment methods are aimed to
reduce pain and inflammation.
- Attempts are also made to slow
down joint damage and try and
improve general well- being.
Here comes the role of
Stem Cell therapy.
www.globalstemgenn.com
MANAGEMENT OF RHEUMATOID
ARTHRITIS CONTD…
• RA management is a Team Effort, headed by a
rheumatologist together with other health
professionals such as physiotherapists,
occupational therapists, nurses, psychologists,
orthopaedic surgeons and social workers.
• The treatment modalities include
counselling, medication, physiotherapy
and ultimately Stem Cell therapy or
Surgery.
www.globalstemgenn.com
MEDICATIONS FOR RA
• NSAIDs are lifeline.
• CORTICOSTEROIDS – the role
of corticosteroids in RA is
highly controversial.
DISEASE - MODIFYING DRUGS IN
Rheumatoid Arthritis
• Injectables gold salts, certain cancer drugs
like Methotrexate, anti-malarial agents like
Hydroxychloroquin and anti-inflammatory
drugs of bowels like Sulfasalazine are some
of the popular disease – modifying drugs
used in Rheumatoid Arthritis.
• These drugs need proper & intensive
monitoring and least to decrease side effects.
www.globalstemgenn.com
• STEM CELL THERAPY IS QUITE
HELPFUL IN PATIENTS NOT
RESPONDING TO
CONVENTIONAL TREATMENT.
• Stem cell therapy - does
improve the quality of life and
helps getting rid of most of the
manifestations of Rheumatoid
Arthritis.
World Research with
Stem Cell Treatment in Rheumatoid
Arthritis
Conclusion
WORLD RESEARCH ON Rheumatoid Arthritis
WITH STEM CELL THERAPY
• MSC therapy may be valid alternative for
rheumatoid arthritis with chronic knee
arthritis.
• The intervention is simple, does not require
hospitalization or surgery, provides pain
relief, and significantly improves cartilage
qualty & quality of life.
Stem cell therapy improves the
quality of life.
However the response
Varies from patient
to patient
WORLD RESEARCH ON Rheumatoid Arthritis
WITH STEM CELL THERAPY
We are happy with Stem Cell therapy in
improving the quality of life and mobility in
Rheumatoid Arthhritis
Global stemgenn makes suitable stem
cell therapy available to the ailing
patient only after thorough
scientific deliberations and
meticulous counseling of patient &
family with experts.
www.globalstemgenn.com
Our USP
• World class clinicians and experts from
Regenerative medicine.
• State of the art, in-house stem cell lab to maximize the
yield of good quality Stem Cells
• Accurate treatment protocols for “relevant disorders”
• Proven results and experience in handling complex case
• We use Autologous stem cells for Stem Cell Therapy
(Bone Marrow, Fat, Blood)
www.globalstemgenn.com
• Autologous cells for homologous use
• Same setting surgery
• Minimal manipulation of cells
• Don’t promote therapeutic results
You should know
FDA – guidelines…
• This is a patient-funded clinical trial
• Stem Cell Therapy is NOT COVERED BY
INSURANCE
• Public undertakings DO ALLOW in GUJARAT
• The cost of the therapy ranges & mainly depends on
the complexity of the case
Fees and Insurance cover
Global stemgenn offer you stem cell
therapy using latest technology.
These stem cells could be of various types viz.
Hematopoietic (CD 34+), Mesenchymal stem cells
(MSCs) that are processed and isolated using Good
Manufacturing Practice (GMP) and Good Lab Practice
(GLP) in accordance with AABB standards.
Our Lab USP
Our overall experience of
Stem cell therapy at Global Stemgenn
- It is completely safe,
Non –Toxic and totally devoid of side effects
with good probability of homing and
engraftment with the parent cell, tissue or
organ.
Patient – Safety
Endorsed by Doctor Pateints
www.globalstemgenn.com
D
O
C
T
O
R
S
TRAINING
CENTRE
ISO 14001:2004
…..Caring hearts, healing hands
Is our PARENT organization
ADDRESS
11 Gagan Vihar, Near Karkari Morh Flyover,
Delhi - 51
CONTACT US
9599044357(Help line),
9811011690(Watsapp)
011-22414049,22058865
WEBSITE :
www.globalstemgenn.com
www. Stemgenn.com
www.lifecarecentre.in
E-MAIL ID
Contact@globalstemgenn.com
Contact @stemgenn.com
A UNIT
OF ISO 14001:2004 (EMS)
…..Caring hearts, healing hands
ISO 9001:2008
ISO 9001:2008

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Medical Facts of STEM CELL THERAPY in Rheumatoid Arthritis

  • 1. Medical Facts of STEM CELL THERAPY Dr. Sharda Jain Mr. Prabhu Mishra DR. YOGESH AGARWALA Dr. Rajesh Dhall Dr. Rashmi Jain Dr. Indu Tyagi Ms. Himani Agnihotri in Rheumatoid Arthritis Public Awareness series
  • 2. WELCOME to world of STEM CELL THERAPY – a Medical Revolution in Rheumatoid Arthritis to manage Day Today Life & Halt the Disease Process
  • 3. RHEUMATOID ARTHRITIS Rheumatoid arthritis or RA is an autoimmune condition, which primarily affects the synovium in the knee, causing inflammation followed by destruction of the joint surfaces. www.globalstemgenn.com Advance Disease Pictures
  • 4. SYMPTOMS • Initial symptoms of RA are generally pain and morning stiffness. • RA in the knee can be isolated or be a part of generalized pain. • The disease, which starts as synovitis in the knee, progresses to destroy the joint.
  • 5. SYMPTOMS • Classically, there would be involvement of small joints of the hands and feet.
  • 6. SYMPTOMS contd….. • The disease is characterized by episodes of acute inflammation interspersed with periods of remission. • When the arthritis takes toll on the cartilage of the knee, the joint becomes deformed and painful even to the slightest of movement. www.globalstemgenn.com
  • 7. LAB TEST • Blood tests can be useful to make a diagnosis of RA. Blood tests will show the presence of the antibody called rheumatoid factor (RA test). HOWEVER, ABSENCE OF THE ANTIBODY DOES NOT EXCLUDE RA. • X-RAYS IN EARLY RA CAN BE NORMAL, as the involvement would limit to the synovium. • Over a long period of time, X-rays will reveal destruction of joint margins, deformity, bone loss and severe osteoporosis. www.globalstemgenn.com
  • 8. Please remember • It is Bad and Progressive disease, that leaves you incapable to do anything if you don’t take timely action.
  • 9. MANAGEMENT AND TREATMENT •It is now universally acceptable that there is NO complete cure for RA.
  • 10. TREATMENT IS MAINLY SUPPORTIVE - Treatment methods are aimed to reduce pain and inflammation. - Attempts are also made to slow down joint damage and try and improve general well- being. Here comes the role of Stem Cell therapy. www.globalstemgenn.com
  • 11. MANAGEMENT OF RHEUMATOID ARTHRITIS CONTD… • RA management is a Team Effort, headed by a rheumatologist together with other health professionals such as physiotherapists, occupational therapists, nurses, psychologists, orthopaedic surgeons and social workers. • The treatment modalities include counselling, medication, physiotherapy and ultimately Stem Cell therapy or Surgery. www.globalstemgenn.com
  • 12. MEDICATIONS FOR RA • NSAIDs are lifeline. • CORTICOSTEROIDS – the role of corticosteroids in RA is highly controversial.
  • 13. DISEASE - MODIFYING DRUGS IN Rheumatoid Arthritis • Injectables gold salts, certain cancer drugs like Methotrexate, anti-malarial agents like Hydroxychloroquin and anti-inflammatory drugs of bowels like Sulfasalazine are some of the popular disease – modifying drugs used in Rheumatoid Arthritis. • These drugs need proper & intensive monitoring and least to decrease side effects. www.globalstemgenn.com
  • 14. • STEM CELL THERAPY IS QUITE HELPFUL IN PATIENTS NOT RESPONDING TO CONVENTIONAL TREATMENT. • Stem cell therapy - does improve the quality of life and helps getting rid of most of the manifestations of Rheumatoid Arthritis. World Research with Stem Cell Treatment in Rheumatoid Arthritis
  • 15. Conclusion WORLD RESEARCH ON Rheumatoid Arthritis WITH STEM CELL THERAPY • MSC therapy may be valid alternative for rheumatoid arthritis with chronic knee arthritis. • The intervention is simple, does not require hospitalization or surgery, provides pain relief, and significantly improves cartilage qualty & quality of life.
  • 16. Stem cell therapy improves the quality of life. However the response Varies from patient to patient WORLD RESEARCH ON Rheumatoid Arthritis WITH STEM CELL THERAPY
  • 17. We are happy with Stem Cell therapy in improving the quality of life and mobility in Rheumatoid Arthhritis Global stemgenn makes suitable stem cell therapy available to the ailing patient only after thorough scientific deliberations and meticulous counseling of patient & family with experts. www.globalstemgenn.com
  • 18. Our USP • World class clinicians and experts from Regenerative medicine. • State of the art, in-house stem cell lab to maximize the yield of good quality Stem Cells • Accurate treatment protocols for “relevant disorders” • Proven results and experience in handling complex case • We use Autologous stem cells for Stem Cell Therapy (Bone Marrow, Fat, Blood) www.globalstemgenn.com
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  • 20. • Autologous cells for homologous use • Same setting surgery • Minimal manipulation of cells • Don’t promote therapeutic results You should know FDA – guidelines…
  • 21. • This is a patient-funded clinical trial • Stem Cell Therapy is NOT COVERED BY INSURANCE • Public undertakings DO ALLOW in GUJARAT • The cost of the therapy ranges & mainly depends on the complexity of the case Fees and Insurance cover
  • 22. Global stemgenn offer you stem cell therapy using latest technology. These stem cells could be of various types viz. Hematopoietic (CD 34+), Mesenchymal stem cells (MSCs) that are processed and isolated using Good Manufacturing Practice (GMP) and Good Lab Practice (GLP) in accordance with AABB standards. Our Lab USP
  • 23. Our overall experience of Stem cell therapy at Global Stemgenn - It is completely safe, Non –Toxic and totally devoid of side effects with good probability of homing and engraftment with the parent cell, tissue or organ. Patient – Safety Endorsed by Doctor Pateints www.globalstemgenn.com
  • 25. ISO 14001:2004 …..Caring hearts, healing hands Is our PARENT organization
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  • 27. ADDRESS 11 Gagan Vihar, Near Karkari Morh Flyover, Delhi - 51 CONTACT US 9599044357(Help line), 9811011690(Watsapp) 011-22414049,22058865 WEBSITE : www.globalstemgenn.com www. Stemgenn.com www.lifecarecentre.in E-MAIL ID Contact@globalstemgenn.com Contact @stemgenn.com A UNIT OF ISO 14001:2004 (EMS) …..Caring hearts, healing hands ISO 9001:2008 ISO 9001:2008