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Stroke and
Nutrition
Dr. Krizia Ferrini
RDN, MSc, PhD
Disclosure of speaker‘s
interest
• No conflict of interest
• Nutrition Scientific Commettee Council member -
American Society for Nutrition (ASN)
• Member - European Society for Parenteral and Enteral
Nutrition (ESPEN)
Outline –Nutrition
support after stroke
• Nutrition Care Process in Stroke Rehabilitation
• Clinical Activities- Interfaces
• Artificial Nutrition (enteral and parenteral Nutrition)
• Dysphagia (IDDSI Framework)
• Healthy Nutrition Guidelines
• Recommendations
Outline –Nutrition
support after stroke
• Nutrition Care Process in Stroke Rehabilitation
• Clinical Activities- Interfaces
• Artificial Nutrition (enteral and parenteral Nutrition)
• Dysphagia (IDDSI Framework)
• Healthy Nutrition Guidelines
• Recommendations
Nutrition Care Process
• Nutrition Assessment
• Food and/or Nutrient Delivery
• Nutrition Education
• Nutrition Counselling
Nutrition Care Process
http://dysphagia.ie
Nutritional Assessment
The purpose of nutritional assessment is to:
• Identify individuals at risk of becoming malnourished
• Identify individuals who are malnourished
Nutritional Assessment
1. History
2. Physical examination
3. Laboratory Data in Nutrition
Assessment
Nutritional Assessment
1. History
• ↓ weight in last 6 months – e.g. Malnutrition Universal
Screening Tool (MUST)
• Changes in dietary intake (e.g. Dietary History, Food diary,
Observed Food Consumption)
• Hydration Status
• Quality of diet (e.g. Mediterranean Diet Score)
Nutritional Assessment
1. History
• Gastrointestinal symptoms (i.e. Bristol Stool Chart)
• Functional capacity – i.e. Eating Assessment Tool (EAT-10)
(if the VFS or FEES not possible)
• Disease and its relation to nutritional requirements
Nutritional Assessment
2. Physical examination
Detection of relevant signs helps in establishing the nutritional
diagnosis
• Subcutaneous fat (i.e. waist circumference, bio impedance
analysis)
• Muscle wasting
• Ankle edema
• Sacral edema
• Ascites
Nutritional Assessment
Classification
Source: Adapted from WHO, 1995, WHO,
2000 and WHO 2004.
BMI- Principal cut off points Additional cut-off points
Underweight <18.50 <18.50
Severe malnutrition <16.00 <16.00
Moderate malnutrition 16.00–16.99 16.00–16.99
Mild malnutrition 17.00–18.49 17.00–18.49
Normal range 18.50–24.99 18.50–22.99
23.00–24.99
Overweight >25.00 >25.00
Pre-obese 25.00–29.99 25.00–27.49
27.50–29.99
Obese >30.00 >30.00
Obese class I 30.00–34.99 30.00–32.49
32.50–34.99
Obese class II 35.00–39.99 35.00–37.49
37.50–39.99
Obese class III
(morbid obesity)
>40.00 >40.00
Nutritional Assessment
2. Physical examination
Health risk Women Men
Low 0.80 or lower 0.95 or lower
Moderate 0.81–0.85 0.96–1.0
High 0.86 or higher 1.0 or higher
Online Image Online Image
Nutritional Assessment
Online Image
Nutritional Assessment
3. Evaluation of Laboratory Data in Nutrition
Assessment
• Used in nutrition assessment (a clinical sign supporting
nutrition diagnosis)
• Assessment for Protein-Calorie Malnutrition
• Used in Monitoring and Evaluation of the patient
response to nutritional intervention
Nutritional Assessment
3. Evaluation of Laboratory Data in Nutrition
Assessment
• Hormonal and cell-mediated response to stress
• Negative acute-phase respondents
• Positive acute-phase respondents
• Nitrogen balance
Nutritional Assessment
3. Evaluation of Laboratory Data in
Nutrition Assessment
• Hepatic transport proteins
• Albumin
• Transferrin
• Prealbumin
• Retinol-binding protein
• C-reactive protein
• Creatinine
Nutritional Assessment
3. Evaluation of Laboratory Data in
Nutrition Assessment
• Inflammation:
• hs-CRP
• Homocysteine
• Markers of Malabsorption
• Fecal fat
• Fat-soluble vitamins
• Vitamin D
Nutritional Assessment
3. Evaluation of Laboratory Data in
Nutrition Assessment
• Lipid Indices of Cardiovascular Risk
• Total cholesterol
• LDL
• HDL: HDL2a, HDL2b, HDL2c, HDL3a, HDLdb
• IDL
• VLDL
• Lp(a)
Nutritional Assessment
3. Evaluation of Laboratory Data in
Nutrition Assessment
2018AHA/ACC/AACVPR/AAPA/ABC/ACPM/ADA
/AGS/APhA/ASPC/NLA/PCNA
Guideline on the Management of Blood Cholesterol
A Report of the American College of
Cardiology/American Heart Association Task Force on
Clinical Practice Guidelines
Outline –Nutrition
support after stroke
• Nutrition Care Process in Stroke Rehabilitation
• Clinical Activities- Interfaces
• Artificial Nutrition (enteral and parenteral Nutrition)
• Dysphagia (IDDSI Framework)
• Healthy Nutrition Guidelines
• Recommendations
Clinical Activities- Interfaces
Clinical Activities- Interfaces
• Medical doctors (understanding of the aetiology, treatment, prognosis and
comorbidities associated with neurological patients)
• Clinical researchers (i.e. providing remote monitoring at home with mobile
Health technology application)
• Nurses (Artificial Nutrition Management + weekly anthropometric
assessments)
• Speech therapists (dysphagia - diagnosis and treatment)
• Neuropsychologists (Nutrition Counselling Guidelines in Neurological
Patients)
• Movement therapists (development energy expenditure concept)
• Occupational therapists (counselling methods helpful for daily life, cooking
groups)
Outline –Nutrition
support after stroke
• Nutrition Care Process in Stroke Rehabilitation
• Clinical Activities- Interfaces
• Artificial Nutrition (enteral and parenteral
Nutrition)
• Dysphagia (IDDSI Framework)
• Healthy Nutrition Guidelines
• Recommendations
Artificial Nutrition (enteral and
parenteral Nutrition)
http://www.crohnscolitisfoundation.org
Artificial Nutrition (enteral and
parenteral Nutrition)
• Partial Enteral Nutrition (PEN) = 30-50 % calories
through formula and the remainder is from solid food or a
regular diet
• Exclusive Enteral Nutrition (EEN) = 100 % calories
through formula; you do not eat any regular food
• Dietetic Products and Foods for Special Medical
Purposes
Artificial Nutrition (enteral and
parenteral Nutrition)
• Patients with prolonged severe dysphagia after stroke that
presumably last for more than 7 days should receive early (not
more than 72 h) enteral tube feeding
• Critically ill stroke patients with decreased level of
consciousness that need mechanical ventilation should receive
early (not more than 72 h) enteral tube feeding
• If enteral feeding is likely necessary for a longer period of time
(>28 days), a PEG should be chosen and placed in a stable
clinical phase (after 14-28 days)
Outline –Nutrition
support after stroke
• Nutrition Care Process in Stroke Rehabilitation
• Clinical Activities- Interfaces
• Artificial Nutrition (enteral and parenteral Nutrition)
• Dysphagia (IDDSI Framework)
• Healthy Nutrition Guidelines
• Recommendations
Dysphagia
stroke.org.uk
Dysphagia
Signs of swallowing problems:
• coughing or choking when patient is eating or drinking
• food or drink going down the wrong way
• still having food or drink left in the mouth after
swallowed
Dysphagia
Signs of swallowing problems:
• not being able to chew food properly
• taking a long time to swallow or finish a meal
• being short of breath when the patient is swallowing
Dysphagia
The IDDSI framework
https://iddsi.org/framework/
Dysphagia : International
Dysphagia Diet
Standardisation Initiative
(IDDSI)
• 2013
• Goal: developing new global standardised terminology
and definitions to describe texture modified foods and
thickened liquids used for individuals with dysphagia of
all ages, in all care settings, and all cultures
Dysphagia : International
Dysphagia Diet
Standardisation Initiative
(IDDSI)
• Final dysphagia diet framework consisting of a
continuum of 8 levels (0-7)
• Levels are identified by numbers, text labels and colour
codes
Dysphagia
New Dysphagia Diets and Fluids
https://iddsi.org/framework/
Outline –Nutrition
support after stroke
• Nutrition Care Process in Stroke Rehabilitation
• Clinical Activities- Interfaces
• Artificial Nutrition (enteral and parenteral Nutrition)
• Dysphagia (IDDSI Framework)
• Healthy Nutrition Guidelines
• Recommendations
Healthy Nutrition
Guidelines
• MIND diet
• ↓cognitive decline in
stroke survivors
• rich in whole foods,
including fruits and
vegetables
• elements of the
Mediterranean-style diet
and the DASH diet
American Stroke Association's International Stroke Conference 2018
Healthy Nutrition
Guidelines
Outline –Nutrition
support after stroke
• Nutrition Care Process in Stroke Rehabilitation
• Clinical Activities- Interfaces
• Artificial Nutrition (enteral and parenteral Nutrition)
• Dysphagia (IDDSI Framework)
• Healthy Nutrition Guidelines
• Recommendations
Recommendations
• All patients should be screened for malnutrition at the time
of admission and weekly thereafter
• Stroke patients should also have their hydration assessed on
admission, reviewed regularly and managed so that normal
hydration is maintained
• Nutrition support should be initiated for people with stroke
who are at risk of malnutrition. This may include oral
nutritional supplements (ONS), specialist dietary advice
and/or enteral tube feeding (ETF)
Recommendations
• People with dysphagia should be given food, fluids and
medications modified in a form that can be swallowed
without aspiration
• Ensure palatable diet, presented in a way to promote
nutritional intake
Recommendations
References
• Burgos R. et al, ESPEN Guideline Clinical Nutrition in Neurology. Clin Nutr 37 (2018) 354-
396
• 2018AHA/ACC/AACVPR/AAPA/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA
Guideline on the Management of Blood Cholesterol A Report of the American College of
Cardiology/American Heart Association Task Force on Clinical Practice Guidelines
• The International Dysphagia Diet Standardisation Initiative (http://iddsi.org/)
• Morris MC et al. , MIND diet slows cognitive decline with aging, Alzheimers Dement 2015
September ; 11(9): 1015–1022. doi:10.1016/j.jalz.2015.04.011
• Guideline Clinical Nutrition in Neurology. Clin Nutr (in press) Hookway C., Gomes F.,
Weekes C.E. (2015) Royal College of Physicians Intercollegiate Stroke Working Party
evidence-based guidelines for the secondary prevention of stroke through nutritional or
dietary modification. J Hum Nutr Diet. 28(2):107-125.
Thanks

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Stroke and Nutrition - Dr. Krizia Ferrini

  • 1. Stroke and Nutrition Dr. Krizia Ferrini RDN, MSc, PhD
  • 2. Disclosure of speaker‘s interest • No conflict of interest • Nutrition Scientific Commettee Council member - American Society for Nutrition (ASN) • Member - European Society for Parenteral and Enteral Nutrition (ESPEN)
  • 3. Outline –Nutrition support after stroke • Nutrition Care Process in Stroke Rehabilitation • Clinical Activities- Interfaces • Artificial Nutrition (enteral and parenteral Nutrition) • Dysphagia (IDDSI Framework) • Healthy Nutrition Guidelines • Recommendations
  • 4. Outline –Nutrition support after stroke • Nutrition Care Process in Stroke Rehabilitation • Clinical Activities- Interfaces • Artificial Nutrition (enteral and parenteral Nutrition) • Dysphagia (IDDSI Framework) • Healthy Nutrition Guidelines • Recommendations
  • 5. Nutrition Care Process • Nutrition Assessment • Food and/or Nutrient Delivery • Nutrition Education • Nutrition Counselling
  • 7. Nutritional Assessment The purpose of nutritional assessment is to: • Identify individuals at risk of becoming malnourished • Identify individuals who are malnourished
  • 8. Nutritional Assessment 1. History 2. Physical examination 3. Laboratory Data in Nutrition Assessment
  • 9. Nutritional Assessment 1. History • ↓ weight in last 6 months – e.g. Malnutrition Universal Screening Tool (MUST) • Changes in dietary intake (e.g. Dietary History, Food diary, Observed Food Consumption) • Hydration Status • Quality of diet (e.g. Mediterranean Diet Score)
  • 10. Nutritional Assessment 1. History • Gastrointestinal symptoms (i.e. Bristol Stool Chart) • Functional capacity – i.e. Eating Assessment Tool (EAT-10) (if the VFS or FEES not possible) • Disease and its relation to nutritional requirements
  • 11. Nutritional Assessment 2. Physical examination Detection of relevant signs helps in establishing the nutritional diagnosis • Subcutaneous fat (i.e. waist circumference, bio impedance analysis) • Muscle wasting • Ankle edema • Sacral edema • Ascites
  • 12. Nutritional Assessment Classification Source: Adapted from WHO, 1995, WHO, 2000 and WHO 2004. BMI- Principal cut off points Additional cut-off points Underweight <18.50 <18.50 Severe malnutrition <16.00 <16.00 Moderate malnutrition 16.00–16.99 16.00–16.99 Mild malnutrition 17.00–18.49 17.00–18.49 Normal range 18.50–24.99 18.50–22.99 23.00–24.99 Overweight >25.00 >25.00 Pre-obese 25.00–29.99 25.00–27.49 27.50–29.99 Obese >30.00 >30.00 Obese class I 30.00–34.99 30.00–32.49 32.50–34.99 Obese class II 35.00–39.99 35.00–37.49 37.50–39.99 Obese class III (morbid obesity) >40.00 >40.00
  • 13. Nutritional Assessment 2. Physical examination Health risk Women Men Low 0.80 or lower 0.95 or lower Moderate 0.81–0.85 0.96–1.0 High 0.86 or higher 1.0 or higher Online Image Online Image
  • 15. Nutritional Assessment 3. Evaluation of Laboratory Data in Nutrition Assessment • Used in nutrition assessment (a clinical sign supporting nutrition diagnosis) • Assessment for Protein-Calorie Malnutrition • Used in Monitoring and Evaluation of the patient response to nutritional intervention
  • 16. Nutritional Assessment 3. Evaluation of Laboratory Data in Nutrition Assessment • Hormonal and cell-mediated response to stress • Negative acute-phase respondents • Positive acute-phase respondents • Nitrogen balance
  • 17. Nutritional Assessment 3. Evaluation of Laboratory Data in Nutrition Assessment • Hepatic transport proteins • Albumin • Transferrin • Prealbumin • Retinol-binding protein • C-reactive protein • Creatinine
  • 18. Nutritional Assessment 3. Evaluation of Laboratory Data in Nutrition Assessment • Inflammation: • hs-CRP • Homocysteine • Markers of Malabsorption • Fecal fat • Fat-soluble vitamins • Vitamin D
  • 19. Nutritional Assessment 3. Evaluation of Laboratory Data in Nutrition Assessment • Lipid Indices of Cardiovascular Risk • Total cholesterol • LDL • HDL: HDL2a, HDL2b, HDL2c, HDL3a, HDLdb • IDL • VLDL • Lp(a)
  • 20. Nutritional Assessment 3. Evaluation of Laboratory Data in Nutrition Assessment 2018AHA/ACC/AACVPR/AAPA/ABC/ACPM/ADA /AGS/APhA/ASPC/NLA/PCNA Guideline on the Management of Blood Cholesterol A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines
  • 21. Outline –Nutrition support after stroke • Nutrition Care Process in Stroke Rehabilitation • Clinical Activities- Interfaces • Artificial Nutrition (enteral and parenteral Nutrition) • Dysphagia (IDDSI Framework) • Healthy Nutrition Guidelines • Recommendations
  • 23. Clinical Activities- Interfaces • Medical doctors (understanding of the aetiology, treatment, prognosis and comorbidities associated with neurological patients) • Clinical researchers (i.e. providing remote monitoring at home with mobile Health technology application) • Nurses (Artificial Nutrition Management + weekly anthropometric assessments) • Speech therapists (dysphagia - diagnosis and treatment) • Neuropsychologists (Nutrition Counselling Guidelines in Neurological Patients) • Movement therapists (development energy expenditure concept) • Occupational therapists (counselling methods helpful for daily life, cooking groups)
  • 24. Outline –Nutrition support after stroke • Nutrition Care Process in Stroke Rehabilitation • Clinical Activities- Interfaces • Artificial Nutrition (enteral and parenteral Nutrition) • Dysphagia (IDDSI Framework) • Healthy Nutrition Guidelines • Recommendations
  • 25. Artificial Nutrition (enteral and parenteral Nutrition) http://www.crohnscolitisfoundation.org
  • 26. Artificial Nutrition (enteral and parenteral Nutrition) • Partial Enteral Nutrition (PEN) = 30-50 % calories through formula and the remainder is from solid food or a regular diet • Exclusive Enteral Nutrition (EEN) = 100 % calories through formula; you do not eat any regular food • Dietetic Products and Foods for Special Medical Purposes
  • 27. Artificial Nutrition (enteral and parenteral Nutrition) • Patients with prolonged severe dysphagia after stroke that presumably last for more than 7 days should receive early (not more than 72 h) enteral tube feeding • Critically ill stroke patients with decreased level of consciousness that need mechanical ventilation should receive early (not more than 72 h) enteral tube feeding • If enteral feeding is likely necessary for a longer period of time (>28 days), a PEG should be chosen and placed in a stable clinical phase (after 14-28 days)
  • 28. Outline –Nutrition support after stroke • Nutrition Care Process in Stroke Rehabilitation • Clinical Activities- Interfaces • Artificial Nutrition (enteral and parenteral Nutrition) • Dysphagia (IDDSI Framework) • Healthy Nutrition Guidelines • Recommendations
  • 30. Dysphagia Signs of swallowing problems: • coughing or choking when patient is eating or drinking • food or drink going down the wrong way • still having food or drink left in the mouth after swallowed
  • 31. Dysphagia Signs of swallowing problems: • not being able to chew food properly • taking a long time to swallow or finish a meal • being short of breath when the patient is swallowing
  • 33. Dysphagia : International Dysphagia Diet Standardisation Initiative (IDDSI) • 2013 • Goal: developing new global standardised terminology and definitions to describe texture modified foods and thickened liquids used for individuals with dysphagia of all ages, in all care settings, and all cultures
  • 34. Dysphagia : International Dysphagia Diet Standardisation Initiative (IDDSI) • Final dysphagia diet framework consisting of a continuum of 8 levels (0-7) • Levels are identified by numbers, text labels and colour codes
  • 35. Dysphagia New Dysphagia Diets and Fluids https://iddsi.org/framework/
  • 36. Outline –Nutrition support after stroke • Nutrition Care Process in Stroke Rehabilitation • Clinical Activities- Interfaces • Artificial Nutrition (enteral and parenteral Nutrition) • Dysphagia (IDDSI Framework) • Healthy Nutrition Guidelines • Recommendations
  • 37. Healthy Nutrition Guidelines • MIND diet • ↓cognitive decline in stroke survivors • rich in whole foods, including fruits and vegetables • elements of the Mediterranean-style diet and the DASH diet American Stroke Association's International Stroke Conference 2018
  • 39. Outline –Nutrition support after stroke • Nutrition Care Process in Stroke Rehabilitation • Clinical Activities- Interfaces • Artificial Nutrition (enteral and parenteral Nutrition) • Dysphagia (IDDSI Framework) • Healthy Nutrition Guidelines • Recommendations
  • 40. Recommendations • All patients should be screened for malnutrition at the time of admission and weekly thereafter • Stroke patients should also have their hydration assessed on admission, reviewed regularly and managed so that normal hydration is maintained • Nutrition support should be initiated for people with stroke who are at risk of malnutrition. This may include oral nutritional supplements (ONS), specialist dietary advice and/or enteral tube feeding (ETF)
  • 41. Recommendations • People with dysphagia should be given food, fluids and medications modified in a form that can be swallowed without aspiration • Ensure palatable diet, presented in a way to promote nutritional intake
  • 42. Recommendations References • Burgos R. et al, ESPEN Guideline Clinical Nutrition in Neurology. Clin Nutr 37 (2018) 354- 396 • 2018AHA/ACC/AACVPR/AAPA/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA Guideline on the Management of Blood Cholesterol A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines • The International Dysphagia Diet Standardisation Initiative (http://iddsi.org/) • Morris MC et al. , MIND diet slows cognitive decline with aging, Alzheimers Dement 2015 September ; 11(9): 1015–1022. doi:10.1016/j.jalz.2015.04.011 • Guideline Clinical Nutrition in Neurology. Clin Nutr (in press) Hookway C., Gomes F., Weekes C.E. (2015) Royal College of Physicians Intercollegiate Stroke Working Party evidence-based guidelines for the secondary prevention of stroke through nutritional or dietary modification. J Hum Nutr Diet. 28(2):107-125.