2. 2020
2026
9.13 billion
US$
12.23 billion
US$
Global Topical Pain Relief Market Size
• Global topical pain relief market
size is about (9.13 billion US$) in
2020 and expected to reach (12.23
billion US$) by 2026, WITH CAGR
OF 6.7%
3. Pain Scientific Facts
24.4% of population have
joint pain.
(60 – 85)% of the
population has had non-
specific muscle pain at
some time or other.
Inflammation is the most
common reason for joint
pain
Muscle pain is most often
related to tension, overuse,
or muscle injury from
exercise or hard physical
work..
Exercise is important to
improve synovial fluid,
which is finally protect
joints cartilages.
The brains of people with
chronic backaches are as
much as 11 percent
smaller than those of non-
sufferers.
5. EmuFlex® Cream … Product Description
EmuFlex® Cream is a natural,
scientific-based and well-studied
formula, with high and approved
efficacy for the treatment of Joint
pain, muscles aches and cartilage
rejuvenation.
7. 7
Anti-inflammatory and
analgesic effect
EmuFlex® Cream … Active ingredients mechanism of action
Muscle pain and
analgesic effect
* Linolenic acid (inhibit
leukocyte activation)-(Emu oil).
* Salicin (Inhibit COX-2)-(White
willow bark).
* Gingerol (Inhibit COX-2 and
TNF-Alpha)-(Ginger root oil).
* MSM (Inhibit NF-KB)-(MSM).
* Increase blood flow with
analgesic effect.
* Activate transient receptor
potential melastatin 8 (TRPM8)
receptors on sensory nerves and
on the vasculature inducing a
cooling sensation on the skin.
(Peppermint oil)
* Stimulate synthesis of
synovial fluid, and inhibit
degradation and improve
healing of articular cartilage.
(Glucosamine sulfate and
MSM)
Cartilage and synovial
fluid rejuvenation
8. EmuFlex® Cream … Distinctive
innovative solution
All topical competitors that contains
glucosamine, faced a real problem of
poor absorption of glucosamine through
skin, due to the large molecule of
glucosamine, but for EmuFlex® Cream
formula, because it has specific and
calculated concentration of (Oleic acid)
which comes from Emu oil, works as a
carrier and enhances the absorption of
glucosamine through skin.
10. EmuFlex® Cream … Key benefits
1
EmuFlex®
Cream is
scientifically
approved
formula for
the treatment
of joints pain,
muscle aches
and cartilage
rejuvenation.
2
EmuFlex®
Cream has a
potent anti-
inflammatory
effect.
3
EmuFlex®
Cream has
rapid effect
on muscles
pain and
aches.
4
EmuFlex® Cream
Helps
effectively in
cartilages and
synovial fluid
rejuvenation.
5
EmuFlex® Cream
provides excellent
transdermal
absorption of
glucosamine
sulfate through
(Oleic acid) as a
component from
Emu oil which
acts as a carrier.
11. Scientific References
Anti-inflammatory activity of essential oil from Zingiber Ofiicinalis in animal model
(Molecules-2022)
Preliminary study of the effects of glucosamine sulphate and chondoitrin sulphate on
surgically treated and untreated focal cartilage damage (European cells and materials -
2011)
Emu oil suppresses inflammatory responses of RAW 264 macrophages via inhibition of
NF-kB signaling (Japanese Journal of veterinary Research – 2021)
Methyl Silfonyl Mehan: Applications and safety of novel Dietary supplements
(Nutrients – 2017)
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Effect of white willow bark on delayed onset muscle sorness following resistance training:
A pilot study (The Asian Journal of Kinesiology)
Emu oil for osteoarthritis hand pain (Melainie Cameron B.App. Sc-Research)
12. Scientific References ...
Topical Ginger treatment with a compress or patch for osteoarthritis symptoms
(J Holist Nurs – 2013)
A trnsdermal glucosamine formulation improves osteoarthritis symptoms in an open
clinical survey (International Journal of pharmaceutical science – 2011)
Derma delivery of glucosamine sulphate: Formulation, characterization and
performance evaluation (World Journal of pharmacy and pharmaceutical sciences –
Volume 2)
A randomized , double blind placebo control trial of a topical cream containing
glucosamine sulphate, chondoiritin sulphate and camphor for osteoarthritis of the
knee (Journal of Rheumatology – ISSN-0315-162-X)
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