2. 21.4 billionUSD$
The global wound care market size
The global wound care market size was valued at USD 21.4 billion in
2022 and is expected to expand at a compound annual growth rate
(CAGR) of 4.15% from 2023 to 2030. (Grand View Research)
29.57 billion USD$
3. Wound healing stages
Hemostasis Phase Inflammatory Phase Proliferation Phase
-- Vasoconstriction.
- Platelet
degranulation.
Inhibition of
clotting cascade.
- Fibrin clot
formation.
- Release of
vasoactive
mediators,
cyclokines, and
growth factors.
(5 - 15 minutes)
- Platelet-derived
chemo attractants
and growth factors.
- Neutrophils and
macrophages clean
and remove debris
and foreign
particles.
- Macrophages
perform
phagocytosis, and
release cytokines
and growth factors.
(24 - 48 hrs, up to 2
weeks)
- Re-
epithelialization.
- Granulation.
- Angiogenesis.
- Fibroplasia.
(3 -4 days after
injury, up to 21
days).
Maturation Phase
- Collagen and
extracellular matrix
organization.
- Wound contraction.
- Scar maturation.
(Few days after injury,
up to 2 years)
4. Factors adversely affect wound healing (DID`T HEAL)
Diabetes Infection Drugs
(like steroids)
Nutritional
problems (Like
deficiencies of
protein, vit. A, C
and Zinc)
Tissue
necrosis
Hypoxia
Excessive
tension on
wound
Low
temperature
7. EmuHeal® Cream Mechanism of action, for wound healing
Hemostasis Phase Inflammatory Phase Proliferation Phase
- Bleeding will stop
normally and naturally.
- Prevent wound from
infections (Tea tree oil).
- Easing of wound pain
(Natural sterols and
Linolenic acid), (Emu oil,
Aloe vera)
- Natural sterols (Beta
sitosterol, Lupeol and
Campsterol) and Essential
fatty acid (Linolenic acid)
have anti-inflammatory
effect and is important
incase of prolonged and
not likable wound
inflammation (Emu oil,
Aloe vera).
- Hasten re-epithelialization
and keratinization of wound
(Emu oil, Aloe vera).
- Glucomannan affect
fibroblast growth factor and
stimulate the activity and
proliferation of the cells
(Aloe vera).
- Increase angiogenesis
(Beta sitosterol, Lupeol and
Camsterol) as well as
granulated tissue s (Aloe
vera).
- Possess antioxidant
enzymatic system like
glutathion peroxidase and
superoxide dismutase which
increase healing process
(Emu oil, Aloe vera).
Maturation Phase
- Increase amount of
collagen on wound site
and change in collagen
structure (Emu oil, Aloe
vera).
8. Tea Tree Oil … Approved natural broad spectrum antimicrobial agent
A lot of scientific studies and researches have proven
that Tea Tree Oil is considered the best herbal and
alternative antimicrobial agent with broad spectrum
and negligible bacterial resistance.
It has even proven highly effective in killing Methicillin-
resistance staphylococcus aureus (MRSA).
9. Wounds and burns most common isolated pathogens and the susceptibility data
for bacteria tested against Tea Tree Oil (TTO)
Isolated pathogen Isolated pathogen
percentage
MIC OF
(TTO)
Acinetobacter baumannii 23.6% 1%
Pseudomonas aeruginosa 12% (1-8)%
Staphylococcus aureus 11.2% (0.5-1.25)%
E.Coli 10% (0.08-2)%
MIC: Minimum inhibitory concentration.
10. Diabetic foot ulcers most common isolated pathogens and the susceptibility data
for bacteria tested against Tea Tree Oil (TTO)
Isolated pathogen Isolated pathogen
percentage
MIC OF
(TTO)
Proteus mirabilis 15% 0.038%
Pseudomonas
aeruginosa
22% (1-8)%
Staphylococcus aureus 21% (0.5-1.25)%
E.Coli 12% (0.08-2)%
Klebsiella pneumoniae 17% 0.1%
MIC: Minimum inhibitory concentration.
12. What makes EmuHeal® Cream so unique?
01
02
03
06
05
04
EmuHeal® Cream speeds
up skin healing for
diabetic foot ulcers,
bedsores, wounds and
burns.
EmuHeal® Cream is a cost
effective brand.
.
EmuHeal® Cream formula
has a distinctive anti-
inflammatory,
angiogenesis and anti
oxidant effect.
EmuHeal® Cream formula is
a patented and well-studied
formula.
.
EmuHeal® Cream has a
natural broad spectrum
antimicrobial
ingredients.
EmuHeal® Cream formula
has a wide safety profile,
and can be used without
side effects.
.
13. References
Effect of topical aloe vera on the process of healing
of full-thickness skin burn: a histological and
immunohistochemical study (Journal of Histology & Histopathology
ISSN 2055-091X | Volume 2 | Article 3)
⚫
Naturally derived factors and their role in the promotion
of angiogenesis for the healing of chronic wounds (Angiogenesis
DOI 10.1007/s10456-013-9341-1)
⚫
Melaleuca alternifolia (Tea Tree) Oil: a Review of Antimicrobial
and Other Medicinal Properties (CLINICAL MICROBIOLOGY REVIEWS, Jan. 2006, p. 50–62)
⚫
Tea tree oil as an alternative topical
decolonization agent for methicillin-resistant
Staphylococcus aureus (Journal of Hospital Infection (2000) 46: 236–237)
⚫
Chronic Wound Treatment With Topical Tea Tree Oil (ALTERNATIVE THERAPIES, mar/apr 2011, VOL. 17, NO. 2)
⚫
14. References …
Evaluation the Effect of Melaleuca Alternifolia (tea tree) oil as a New Topical
Therapy in the Treatment of Burn (Indian Journal of Novel Drug delivery 3(4), Oct-Dec, 2011, 264-271)
⚫
Effects of plant sterols derived from Aloe vera gel on human dermal fibroblasts in vitro and on skin condition
in Japanese women ( Clinical, Cosmetic and Investigational Dermatology 2015:8 95–104)
⚫
Emu Oil Topical Use in Dermatology (Milani M , et al., J Clinic Exper Cosme Derma 4: 020)
⚫
Evaluation of Bioactive Potential of an Aloe vera Sterol Extract (Phytother. Res. 27: 864–868 (2013))
⚫
