Current career information.

1. JESSE MULL
jessemull@gmail.com
www.jessemull.com
SUMMARY
Obtaining large numbers of human neurons for drug screening and discovery is impossible. An
alternative strategy is to produce induced pluripotent stem cells from human tissue and
differentiate them to neurons in-vitro. We are currently automating this process so that we can
produce human neurons at scale for hundreds or even thousands of patient cell lines.
As an aspiring software engineer, I use a MEAN stack to produce user friendly tools for high content
imaging data tracking and analysis. I’ve also created two computational models to simulate the
process of synapse development. I know objective C, Java and Javascript well. I use MongoDB and
SQLite. I know enough Python and R to get by at work and my next language will be Scala or
Clojure.
My first open source project is nearing completion. MicroFlex will be the world’s first and most
flexible implementation of a microplate data structure. The MicroFlex library will provide
descriptive statistics, mathematical operations, input/output and numerous other plate based
features. Check back soon for links to the Java version on Github and Maven as well as a tutorial.
The Javascript version for Node.js and AngularJS will follow suit.
My goal is to be employed as a full time software engineer before the end of the year. If my skill set
and interests are a good fit for your company please contact me via e-mail, LinkedIn, Piazza or my
personal website.
SKILLS
Java JavaScript Objective C
HTML5 Unix/Linux OS Unix/Linux Scripting
CSS3 AngularJS Node.js
jQuery Bootstrap MongoDB
SQL Karma.js Gulp.js
ExpressJS High Content Imaging High Throughput Screening
EXPERIENCE
Novartis Institute for Biomedical Research Cambridge, MA 12 / 2014 - Present
Scientist
Computational modeling/statistical analysis of high content imaging data using Java and the ImageJ API.
Production of desktop software tools (Java) for user friendly consumption of high content
imaging data and automated scheduling of complex differentiation protocols.

2. Development of web applications using a combination of tools including Javascript, Node, Karma,
Angular, Bower, RequireJS, Gulp and others.
Development of robust protocols for the differentiation of pluripotent stem cells to various neuronal
subtypes.
Development of functional and phenotypic assays to characterize neurons differentiated from
patient-derived induced pluripotent stem cells.
Large scale automation of the differentiation and characterization of excitatory cortical neurons.
Harvard University Cambridge, MA 09 / 2013 - 12 / 2014
Scientist
Conducted the first ever image-based small molecule screen on human spinal muscular atrophy iPS-
derived motor neurons.
Characterized a novel collection of spinal muscular atrophy iPS cells.
Developed a novel method of fibroblast to motor neuron trans-differentiation that increases
efficiency by 400-500 fold over other published methods.
University of Minnesota Minneapolis, MN 2010 - 2012
Graduate Research Assistant
Investigation into the epigenetic memory retained by myoblast derived induced pluripotent stem cells
and how this memory can be harnessed for the production of skeletal muscle progenitors to treat
muscular dystrophy.
MitoSciences Eugene, OR 2009 - 2010
Research Associate II - Antibody Development
I developed antibodies to mitochondrial targets for a variety of applications and platforms.
MitoSciences Eugene, OR 2008 - 2009
Research Associate I - Pharmaceutical Contract Research
I screened experimental pharmaceutical compounds for mitochondrial toxicity and assisted in the
development of kits for screening biogenesis inhibitors and the extraction of cytoplasmic, nuclear, and
mitochondrial cell fractions to quantify apoptosis.
EDUCATION
Harvard University 2013- 2016
Master of Science, Information Technology , Computer Software Engineering
University of Minnesota-Twin Cities 2010- 2012
Master of Science , Stem Cell Biology
University of Oregon 2003- 2008
Bachelor of Science , Biology, Chemistry, Summa cum Laude
Free Code Camp 2015
Full Stack Web Development , Computer Software Engineering

3. LANGUAGES
Java (Professional) Javascript (Professional) Objective C (Professional)
SQL (Professional) R (Limited) Python (Limited)
ASSOCIATIONS
ISSCR, Watertown Community Garden Steering Committee, Lutheran Social Services, Paul & Sheila
Wellstone Muscular Dystrophy Center