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Thesis by Publication
Workshop and QA Session
Dr Jennifer Rowland
Science, Engineering, and Medicine
Learning Skills Advisor
Dean HDR Office
• Candidate management plan
• University guidelines for thesis by publication
• Individual sections of the thesis
• Further help and support
• Open the floor to further discussion
* Questions permitted throughout *
Thesis by Publication
Workshop and QA Session
http://www.mq.edu.au/policy/docs/hdr_thesis/guideline_by_publication.html
PhD Candidates
Candidature Management Plan
• http://www.hdr.mq.edu.au/information_for/ne
w_candidates/cmp
• 3 year candidature management plan
• In consultation between candidate and
supervisor
o Definition of milestones
o Thesis/publishing plan
o Timeline and deliverables
Candidature Management Plan
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36
SET
UP
GENERATE CONTENT
COMPLETE
• http://www.hdr.mq.edu.au/information_for/new_candidates/cmp
NO LEAVE
1 2 3 4 5 6
Orientation
Attend Commencement Programs
Research Proposal and timeline
Research Proposal confirmed
Ethics applications
Commencement Report
Candidature Management PlanSETUP
• http://www.hdr.mq.edu.au/information_for/new_candidates/cmp
Formal Faculty Review
Candidature Confirmation
Publication and Financial plan finalised
Research design & methodology done
Ethics approved
Thesis completion timetable set
Check HDRO Res Student Profile details
Data collection commences
6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30
Thesis completion timetable revised
Check HDRO Res Student Profile details
Data collection
Annual Report/MUSEQ-R
PGRF applications
Data Analysis
Literature Review (complete/revised) C R
Chapters (draft/final) D D D D D D D F F F F F F
Examiner selection
Presubmission review (faculty)
GENERATE CONTENT
Candidature Management Plan
• http://www.hdr.mq.edu.au/information_for/new_candidates/cmp
Candidature Management Plan
COMPLETE
30 31 32 33 34 35 36
Check HDRO Res Student Profile details
Chapters (draft/final)
F
Examiner selection
Presubmission review (faculty)
Completion report (faculty)
Thesis submission
• http://www.hdr.mq.edu.au/information_for/new_candidates/cmp
NO LEAVE
Orientation
Attend Commencement Programs
Research Proposal and timeline
Research Proposal confirmed
Ethics applications
Commencement Report
Formal Faculty Review
Candidature Confirmation
Publication and Financial plan finalised
Research design & methodology done
Ethics approved
Thesis completion timetable
Check HDRO Res Student Profile details
Annual Report/MUSEQ-R
Data collection
PGRF applications
Data collection
Data Analysis
Literature Review (complete/revised) C R
Chapters (draft/final) D D D D D D D F F F F F F
Examiner selection
Presubmission review (faculty)
Completion report (faculty)
Thesis submission
Candidature Management Plan
Thesis by Publication
A thesis by publication may include relevant papers, including
conference presentations, which have been published, accepted,
submitted or prepared for publication for which at least half of
the research has been undertaken during enrolment.
Thesis by publication may be a better fit with disciplines where
a research question is answered by work in discrete stages or
involves a sequence of related components (e.g., a series of
laboratory experiments or production of creative works).
AP Judi Homewood, AD HDR, FHS
A thesis by publication may include relevant papers, including
conference presentations, which have been published,
accepted, submitted or prepared for publication for which
at least half of the research has been undertaken during
enrolment.
Thesis by publication may be a better fit with disciplines where
a research question is answered by work in discrete stages
or involves a sequence of related components (e.g., a series
of laboratory experiments or production of creative works).
AP Judi Homewood, AD HDR, FHS
Thesis by Publication
• relevant papers/conference presentations
• published, accepted, submitted or prepared
• at least half performed during enrolment
• research question is answered
• stages/sequence of related components
Thesis by Publication
• No reformat of papers needed
• Simple binding together not enough
• Include
• a Critical Introduction to the work
• Sections that LINK the papers together, and
• Concluding Section for material as a whole
OVERALL COHERENCE
HOW EACH PAPER CONTRIBUTES
http://www.mq.edu.au/policy/docs/hdr_thesis/guideline_by_publication.html
http://www.mq.edu.au/policy/docs/hdr_thesis/guideline_by_publication.html
Thesis by Publication
• 2 – 8 papers
sole and joint authorship
• Each paper a thesis chapter
• Not necessarily chronological
• Clear coherent research study presentation
• Maximum 100,000 words
• Under clear authorship protocols
Present with the Code for Responsible Conduct of Research in mind
http://www.mq.edu.au/__data/assets/pdf_file/0019/71065/The20Macquarie20University20Co
de20for20the20Responsible20Conduct20of20Research.pdf
http://www.mq.edu.au/policy/docs/hdr_thesis/guideline_by_publication.html
Paper 1 Paper 2 Paper 3 Paper 4
Thesis by Publication
http://www.mq.edu.au/policy/docs/hdr_thesis/guideline_by_publication.html
Paper 1 Paper 2 Paper 3 Paper 4
INTRODUCTION
CONCLUSIONS
BIBLIOGRAPHY/REFERENCES
TITLE PAGE
STATEMENT OF ORIGINALITY
ABSTRACT/SUMMARY
ACKNOWLEDGEMENTS
TABLE OF CONTENTS
LIST OF CONTRIBUTORS/CONTRIBUTIONS
LIST OF ORIGINAL PUBLICATIONS
AIMS OF STUDY
ABBREVIATIONS
APPENDICES
http://www.mq.edu.au/policy/docs/hdr_thesis/guideline_by_publication.html
Thesis by Publication
• Permission to publish your papers in your thesis
• Format for the manuscript
• Style of writing for joint author papers will
differ from the other thesis sections
o Active or passive language
o Referencing will be central
o Encompasses whole thesis
Thesis Format – PhD, MPhil and MRes
http://www.hdr.mq.edu.au/information_for/current_candidates/thesis_preparation#presentation
cv cv
Double or 1.5
spaced text Double-sided
printing
Medium-weight
paper
High-quality
printing (laser)
BINDINGEDGE
3.5cm margin
on binding
edge 1.5cm margin
cv
cv 1.5cm margin
http://www.mq.edu.au/policy/docs/hdr_thesis/guideline_by_publication.html
TITLE PAGE
• Title of the thesis in full
• Names and degrees of the candidate
• Name of the organisation, institute or laboratory in
which the research was carried out (if applicable)
• Name of the host University Department
• Date when submitted or re-submitted for the degree
• Statement of presentation
cv cv
cv
cv
Intracellular Signalling of IGFI
Jennifer Rowland
BSc. M.Res
Department of Biological Sciences
Faculty of Science and Engineering
Macquarie University
NSW Australia
Presented for the degree of
Doctor of Philosophy
On
February 18, 2016
Investigation of the Properties of
Adipose-Derived Cells and Secretions
Sinead Blaber
Bachelor of Biotechnology (Honours)
University of Technology, Sydney
A thesis submitted in partial fulfilment of the requirements for the degree of
Doctor of Philosophy
Department of Chemistry and Biomolecular Sciences,
Macquarie University
Sydney, Australia
Submitted for examination: November 2012
Final Submission: August 2013
STATEMENT OF ORIGINALITY
This thesis is the result of my own work and
includes nothing which is the outcome of work
done in collaboration except where specifically
indicated in the text. This work has not been
submitted for a higher degree to any other
university or institution.
Jennifer Rowland
DECLARATION
I certify that the work in this thesis entitled “Investigation of the
Properties of Adipose-Derived Cells and Secretions” has not
previously been submitted for a degree nor has it been submitted as
part of requirements for a degree to any other university or
institution other than Macquarie University. I also certify that the
thesis is an original piece of research and it has been written by me.
Any help and assistance that I have received in my research work
and the preparation of the thesis itself have been appropriately
acknowledged.
In addition, I certify that all information sources and literature used
are indicated in the thesis.
The research presented in this thesis was approved by the
Macquarie University Human Research Ethics Committee,
reference number:
Human Ethics Approval:
5201100385 – 2011
Biosafety Approval
5201000874 – 2010
Some of the research presented in this thesis (Chapter 4) was
approved by the University of Queensland’s Animal Ethics
Committee. Confirmation of this approval was provided to the
Macquarie University Animal Ethics Committee.
Animal Ethics Approval:
TETRAQ/331/11/REGENEUS – 2011
Sinead Blaber (4217 4686)
30th November, 2012
DECLARATION
I certify that the work in this thesis entitled “Investigation of the
Properties of Adipose-Derived Cells and Secretions” has not
previously been submitted for a degree nor has it been submitted as
part of requirements for a degree to any other university or
institution other than Macquarie University. I also certify that the
thesis is an original piece of research and it has been written by me.
Any help and assistance that I have received in my research work
and the preparation of the thesis itself have been appropriately
acknowledged.
In addition, I certify that all information sources and literature used
are indicated in the thesis.
The research presented in this thesis was approved by the
Macquarie University Human Research Ethics Committee,
reference number:
Human Ethics Approval:
5201100385 – 2011
Biosafety Approval
5201000874 – 2010
Some of the research presented in this thesis (Chapter 4) was
approved by the University of Queensland’s Animal Ethics
Committee. Confirmation of this approval was provided to the
Macquarie University Animal Ethics Committee.
Animal Ethics Approval:
TETRAQ/331/11/REGENEUS – 2011
Sinead Blaber (4217 4686)
30th November, 2012
STATEMENT OF ORIGINALITY
• Work not submitted elsewhere for a higher
degree
• Indicate that sources of information referenced
• Outline Ethics clearances
http://www.hdr.mq.edu.au/information_for/thesis_examiners/documents/HDR_Thesis_Preparation_Advice_Aug_08.pdf
TABLE OF CONTENTS
• Use a document map/headings to make your table of
contents
• You might want to use Captions to create a separate
table of contents for tables and figures
• Prepages page numbered i, ii, iii, iv…
• Pages numbered 1, 2, 3, 4…
• Sections Numbered 1, 1.1, 1.1.1, 2, 2.1, 2.1.1, 3…
• Paper Numbers I, II, III, IV……
TABLE OF CONTENTS
• May be followed by or associated with:
•List of Tables
•Table 1.1
•Table 1.2 ….
•List of Figures
•Figure 1.1
•Figure 1.2
•Figure 2.1 ….
LIST OF ORIGINAL PUBLICATIONS
This thesis is based on the following original publications,
which are referred to in the text by Roman numbers.
Original publications are reproduced with permission from
their copyright holders.
I Kuja-Panula J*, Kitomäki M*, Yamashiro T, Rouhiainen A,
Rauvala H (2003) AMIGO, a transmembrane protein in axon
tract development, defines a novel protein family with leucine-
rich repeats. Journal of Cell Biology 160(6): 963-973. doi:
10.1083/jcb.200209074a
II Kitomäki M, Jones J, Smith MM, Rauvala H (2005) AMIGO
in oncogenesis. Nature Cell Biology 290(8):34-42. doi:
19.1029/ncb.200308123a
* Equal contributors
LIST OF ORIGINAL PUBLICATIONS
III Kitomäki M, Smart J, Rouhiainen A, Rauvala H (2003)The
role of AMIGO, in neural development in utero.
Submitted to Development.
IV Kitomäki M, Jones J, Smith MM, Rauvala H (2005) AMIGO
in injury repair. Cell, in press.
V Kitomäki M*, Jones J*, Smith MM, Rauvala H (2005) Binding
characteristics of AMIGO: designing therapeutics for burn
therapy. Burns, accepted.
* Equal contributors
LIST OF CONTRIBUTORS
• Papers are single- or co-authored.
• Candidate must specify his/her specific contribution.
• The contribution of others to the preparation of the thesis or
to individual parts of the thesis should be specified
o Acknowledgments
o Footnotes/Endnotes
o List of contributors
• Candidate would usually be principal author
o evidence of this should appear in the appropriate
manner for the discipline.
• Examiners assess quality & extent of candidate’s contribution
LIST OF CONTRIBUTORS
Supervisor Professor Jona Jonasson
Department of Computing
Macquarie University, Australia
Associate Supervisor Associate Professor Dick Wilkins
Waikato Institute of Technology
University of Waikato, New Zealand
Internal Examiner Professor Rob Jones
Maths Hub
Macquarie University, Australia
External Examiner Doctor Tim Robbins
Department of Engineering
Helsinki University, Finland
LIST OF CONTRIBUTORS
Author’s Contribution:
I: In paper I, I performed the cloning experiments to create
the DNA constructs required for the synthetic proteins
and bioactivity assays. I performed all transfection and
transformation experiments, and together with DJW did
fermentation experiments, ion-exchange chromatography,
and crystallization for pure protein extracts. The work was
performed under the supervision of Prof Robert Jones with
the guidance of Dr Geoffrey Smith.
Your contribution specified
LIST OF CONTRIBUTORS
Author’s Contribution:
I: In paper I, all experimental procedures and paper
preparation were performed by myself, JER, with the
exception of the following: 1) Protein expression and
crystallization was done together with DJW; 2) Cell culture
was assisted by TAM; 3) Paper revisions were made by all
contributing authors, under the mentorship of RBJ and
GNS.
* Authors are referred to by their initials, full details in the original article.
Others’ contributions specified
I II III IV V
Conception &
design
DD, MR, NL MR, DD NL, DD DD, MR, DD, MR, MW
Planning &
implementation
DD DD, MR NL, DD, DD, MR, MW DD, MW
Data collection DD, NL DD NL, DD MW, DC, DD DD
Analysis &
interpretation
DD, DD, MR, NL DD, MW, DD, DC, MW, MW, DD,
Writing the article
DD, AT, MR,
NL, LF DD, MR, AT DD, MW, AT,
MR
DD, AT, MW,
MR
MW, DD, AT,
MR
Overall
responsibility
DD DD DD DD MW
DIVISION OF LABOUR IN CO-AUTHORED ARTICLES
AT - Alana Top; DC - Dale Cane; DD - Dephina Dean; LF - Lucy Frond; MR - Mike Riser; MW - Michele Wing; NL - Nancy Light.
LIST OF CONTRIBUTORS
ACKNOWLEDGEMENTS
• Try to group the acknowledgements into paragraphs
“I am immensely grateful to my colleagues in the VTHRC Research
Centre, including: John for assisting with specimen collection, Anna for
helping with formatting, Joseph for securing all my bookings,…..”
• People read your acknowledgements to get a feeling
for who you are as a person, don’t overlook them
• Use exceptional language
ABSTRACT/SUMMARY
• A synopsis / abstract of the thesis
• Summarising the appropriate headings, aims, scope and
conclusion of the thesis
• approximately 300 words for a Doctorate
(Typically 1-2 pages)
ABSTRACT/SUMMARY
• Consider breaking it up into the following sections
1: Introduction of field
2: Identification of gap in field
3: Contribution of each paper in sequence
(refer to by roman numeral, I, II, III….)
4: How the body of work has contributed to
bridging the gap in knowledge
cv cv
cv
cv
Abstract
INTRO
GAP
I
II
III
IV
CONCLUSION
INTRODUCTION
• Ties all the sections together
• May have tables or figures that demonstrate concepts
o ones you have made
o from articles *referenced*
o modified from articles *referenced*
• More expansive than the introduction that might be in a
paper
• History leading to the current study
• Overview of current State of the Art
• Relevance of the current study
• Should naturally lead to the next section where you state the
overall aims of this thesis work
INTRODUCTION
Example Figure from Introduction
http://hdl.handle.net/1959.14/305872
Appetite and
Energy Balance Blood pressure
regulation
Angiogenesis
HemostasisInflammation,
Immunity and acute
phase response
Insulin
sensitivity
Lipid
Metabolism
Figure 1.1 Diverse role of adipose tissue.
Figure adapted from (6).
Figure 1. Position of individual articles I-V within different thematic areas.
Protein
Synthesis
Binding and
Signalling
in vitro
Computational
Modelling
Delivery and Device
Development
Article II
Modelling of
Binding Interactions
of lead molecule
with target receptor
Article I
Developing a
model of lead
molecule and its
synthesis
Article IV
Development of
device for
therapeutic
delivery
Article III
Binding,
Bioactivity and
signalling
efficacy of lead
molecule
INTRODUCTION
Example Figure
from
Introduction
Table 2. Statistics of water resources in Australia (FRU, 2016)
1990 2010 2016
Annual Change
Rate
1990-2016
Dammed water Man made na na 2000 na
(42%)
Naturally occurring na na 3200 na
(58%)
Reservoirs Public 4200 3800 na na
Private 5000 5600 na na
Usage rights (all) Public 8000 7200 6000 15%
Private 1000 3000 5000 500%
Home tank users 800 14000 45000 500%
INTRODUCTION
Example Table from Introduction
AIMS OF THE STUDY
• Simple one-page summary outlining the main aims
of the study overall
• Reflects the main foci of your articles
• You can reference the articles in roman numerals
Given the importance of what you have presented that needs to be addressed in the
introduction, this thesis will address on the following research foci:
I) To determine the manner in which…. through X approach
II) To assess the essential pathway necessary for XXX via the YYY method.
III)……
IV)……
These individual investigations will be presented here referred to by their respective
roman numeral.
METHODS
• Overview of the methods in the whole study
• Perhaps include more detail on specific approaches taken
• Clarify the types of approaches taken throughout the study
The four articles in this thesis mainly employed quantitive analysis of
gene expression and/or cell-analysis research methods (Table 2).
Article I employs …..
Article II utilizes…..
METHODS
Table 2. Methods and data employed in the articles.
Article Analysis Data
I Part 1: Literature review
Part 2: Gap analysis of existing
and required water sources in
the entire Australian continent,
with reference to current
services and suppliers.
Part 1: Peer-reviewed articles and grey literature on issues
related to water resources and dependencies on different
sources throughout Australia between 2001 and 2014
(n=46).
Part 2: The Australian Water Board and services
classification and record of national water supply
provided by the Federal WB report released in 2015.
II Regional mapping GIS data generated from Murray-Darling river basin.
Sourced from state survey published in 2015.a
III Qualitative review Perspectives of state water boards and commercial
suppliers (n=50). Data collected through interview-
delivered questionnaires during June-December 2015).
IV Descriptive statistics and
qualitative content analysis.
Perspectives of local households gathers through open-
and close- ended (n=100). Data collected through
interview-delivered questionnaires during December
2015 in the Murray-Darling river basin.
STUDY CHAPTERS - PAPERS
• Each chapter/paper has an
introductory page/section
• Each introductory page sets the scene introducing the
paper and how it fits into the overall study
Article I
This paper is based on an analysis of ….
Article II
Based on the outcomes of Article I, the next natural
step to drive the work forward was to address …..
STUDY CHAPTERS - PAPERS
• The chapter may be a journal article or
conference proceeding
• It should be published in its original
format
• Permission to publish it in your thesis must be obtained
from the journal where it has been published already
(once it is published the journal owns the material)
• Each article should be able to stand alone
• They should be arranged in a logical flow of ideas, not
necessarily chronological
CONCLUSIONS
• Ties together all of the study findings
• Should be discussed in the same order as the papers
presented
• Refer to the papers by roman numerals (I, I, III…)
• Outline the overall major contributions to the field
• Outline the shortfalls and work that might be pursued
further, FUTURE DIRECTIONS
• Employ figures/diagrams to clarify outcomes where
appropriate
APPENDICES
• Questionnaires – in full
• Technical details of the work/analysis
• Survey Outlines
• Ethics Approvals
• Safety Approvals
• Supplementary Material
• NCBI published sequences
• Extra articles/papers that may be relevant to the
overall thesis
• Look at example theses in your field
• Come and see your Learning Advisor
• Attend WriteNow! Sessions
(Wednesdays, W6B 357, 12-2PM)
• Make sure that you keep an up to date schedule of your
thesis plan (CMP)
• Stay focused on your overall goal, don’t get side-tracked
with peripheral tasks
• Have regular project meetings with your supervisor/mentor
• Start writing as early as possible
Final Thoughts
Want more help?
Check out the writing courses on the HDR workshops page
https://hdrworkshops.mq.edu.au/
Basic Writing
Writing for Publication
Writing a Literature Review
Endnote Courses
Statistics Courses
Thesis Formatting Courses
Survey Design and Data Analysis
and more…
Want more help?
Schedule an appointment with your
Dean HDR Learning Skills Advisor
Humanities
Dr Michelle Jamieson - michelle.jamieson@mq.edu.au
Social Science
Dr Florence Chiew - florence.chiew@mq.edu.au
Science, Engineering, Medicine
Dr Jennifer Rowland - jen.rowland@mq.edu.au
REFERENCE MATERIAL
• HDR OFFICE – HDR Thesis Preparation Advice
http://www.hdr.mq.edu.au/information_for/thesis_examiners/documents/
HDR_Thesis_Preparation_Advice_Aug_08.pdf
• Code for Responsible Conduct of Research
http://www.mq.edu.au/__data/assets/pdf_file/0019/71065/The20Macquari
e20University20Code20for20the20Responsible20Conduct20of20Research.pdf
• Thesis by Publication Guideline
http://www.mq.edu.au/policy/docs/hdr_thesis/guideline_by_publication.ht
ml
Printing
• For students who wish to organise their own printing and
binding we have been using Allbook Bindery at West Ryde
for many years now for the hardcase binding, and they will
also be able to do the printing. Their quality craftsmanship
and service is to be highly recommended.
•
• Quotes and orders can be placed online via:
•
• http://allbookbindery.com/
•
• Contact number is 9807 6026
• Email: contact@allbook

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Thesis by publication and candidature management

  • 1. Thesis by Publication Workshop and QA Session Dr Jennifer Rowland Science, Engineering, and Medicine Learning Skills Advisor Dean HDR Office
  • 2. • Candidate management plan • University guidelines for thesis by publication • Individual sections of the thesis • Further help and support • Open the floor to further discussion * Questions permitted throughout * Thesis by Publication Workshop and QA Session
  • 3. http://www.mq.edu.au/policy/docs/hdr_thesis/guideline_by_publication.html PhD Candidates Candidature Management Plan • http://www.hdr.mq.edu.au/information_for/ne w_candidates/cmp • 3 year candidature management plan • In consultation between candidate and supervisor o Definition of milestones o Thesis/publishing plan o Timeline and deliverables
  • 4. Candidature Management Plan 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 SET UP GENERATE CONTENT COMPLETE • http://www.hdr.mq.edu.au/information_for/new_candidates/cmp
  • 5. NO LEAVE 1 2 3 4 5 6 Orientation Attend Commencement Programs Research Proposal and timeline Research Proposal confirmed Ethics applications Commencement Report Candidature Management PlanSETUP • http://www.hdr.mq.edu.au/information_for/new_candidates/cmp Formal Faculty Review Candidature Confirmation Publication and Financial plan finalised Research design & methodology done Ethics approved Thesis completion timetable set Check HDRO Res Student Profile details Data collection commences
  • 6. 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 Thesis completion timetable revised Check HDRO Res Student Profile details Data collection Annual Report/MUSEQ-R PGRF applications Data Analysis Literature Review (complete/revised) C R Chapters (draft/final) D D D D D D D F F F F F F Examiner selection Presubmission review (faculty) GENERATE CONTENT Candidature Management Plan • http://www.hdr.mq.edu.au/information_for/new_candidates/cmp
  • 7. Candidature Management Plan COMPLETE 30 31 32 33 34 35 36 Check HDRO Res Student Profile details Chapters (draft/final) F Examiner selection Presubmission review (faculty) Completion report (faculty) Thesis submission • http://www.hdr.mq.edu.au/information_for/new_candidates/cmp
  • 8. NO LEAVE Orientation Attend Commencement Programs Research Proposal and timeline Research Proposal confirmed Ethics applications Commencement Report Formal Faculty Review Candidature Confirmation Publication and Financial plan finalised Research design & methodology done Ethics approved Thesis completion timetable Check HDRO Res Student Profile details Annual Report/MUSEQ-R Data collection PGRF applications Data collection Data Analysis Literature Review (complete/revised) C R Chapters (draft/final) D D D D D D D F F F F F F Examiner selection Presubmission review (faculty) Completion report (faculty) Thesis submission Candidature Management Plan
  • 9. Thesis by Publication A thesis by publication may include relevant papers, including conference presentations, which have been published, accepted, submitted or prepared for publication for which at least half of the research has been undertaken during enrolment. Thesis by publication may be a better fit with disciplines where a research question is answered by work in discrete stages or involves a sequence of related components (e.g., a series of laboratory experiments or production of creative works). AP Judi Homewood, AD HDR, FHS A thesis by publication may include relevant papers, including conference presentations, which have been published, accepted, submitted or prepared for publication for which at least half of the research has been undertaken during enrolment. Thesis by publication may be a better fit with disciplines where a research question is answered by work in discrete stages or involves a sequence of related components (e.g., a series of laboratory experiments or production of creative works). AP Judi Homewood, AD HDR, FHS
  • 10. Thesis by Publication • relevant papers/conference presentations • published, accepted, submitted or prepared • at least half performed during enrolment • research question is answered • stages/sequence of related components
  • 11. Thesis by Publication • No reformat of papers needed • Simple binding together not enough • Include • a Critical Introduction to the work • Sections that LINK the papers together, and • Concluding Section for material as a whole OVERALL COHERENCE HOW EACH PAPER CONTRIBUTES http://www.mq.edu.au/policy/docs/hdr_thesis/guideline_by_publication.html
  • 12. http://www.mq.edu.au/policy/docs/hdr_thesis/guideline_by_publication.html Thesis by Publication • 2 – 8 papers sole and joint authorship • Each paper a thesis chapter • Not necessarily chronological • Clear coherent research study presentation • Maximum 100,000 words • Under clear authorship protocols Present with the Code for Responsible Conduct of Research in mind http://www.mq.edu.au/__data/assets/pdf_file/0019/71065/The20Macquarie20University20Co de20for20the20Responsible20Conduct20of20Research.pdf
  • 14. http://www.mq.edu.au/policy/docs/hdr_thesis/guideline_by_publication.html Paper 1 Paper 2 Paper 3 Paper 4 INTRODUCTION CONCLUSIONS BIBLIOGRAPHY/REFERENCES TITLE PAGE STATEMENT OF ORIGINALITY ABSTRACT/SUMMARY ACKNOWLEDGEMENTS TABLE OF CONTENTS LIST OF CONTRIBUTORS/CONTRIBUTIONS LIST OF ORIGINAL PUBLICATIONS AIMS OF STUDY ABBREVIATIONS APPENDICES
  • 15. http://www.mq.edu.au/policy/docs/hdr_thesis/guideline_by_publication.html Thesis by Publication • Permission to publish your papers in your thesis • Format for the manuscript • Style of writing for joint author papers will differ from the other thesis sections o Active or passive language o Referencing will be central o Encompasses whole thesis
  • 16. Thesis Format – PhD, MPhil and MRes http://www.hdr.mq.edu.au/information_for/current_candidates/thesis_preparation#presentation cv cv Double or 1.5 spaced text Double-sided printing Medium-weight paper High-quality printing (laser) BINDINGEDGE 3.5cm margin on binding edge 1.5cm margin cv cv 1.5cm margin
  • 17. http://www.mq.edu.au/policy/docs/hdr_thesis/guideline_by_publication.html TITLE PAGE • Title of the thesis in full • Names and degrees of the candidate • Name of the organisation, institute or laboratory in which the research was carried out (if applicable) • Name of the host University Department • Date when submitted or re-submitted for the degree • Statement of presentation
  • 18. cv cv cv cv Intracellular Signalling of IGFI Jennifer Rowland BSc. M.Res Department of Biological Sciences Faculty of Science and Engineering Macquarie University NSW Australia Presented for the degree of Doctor of Philosophy On February 18, 2016
  • 19. Investigation of the Properties of Adipose-Derived Cells and Secretions Sinead Blaber Bachelor of Biotechnology (Honours) University of Technology, Sydney A thesis submitted in partial fulfilment of the requirements for the degree of Doctor of Philosophy Department of Chemistry and Biomolecular Sciences, Macquarie University Sydney, Australia Submitted for examination: November 2012 Final Submission: August 2013
  • 20. STATEMENT OF ORIGINALITY This thesis is the result of my own work and includes nothing which is the outcome of work done in collaboration except where specifically indicated in the text. This work has not been submitted for a higher degree to any other university or institution. Jennifer Rowland
  • 21. DECLARATION I certify that the work in this thesis entitled “Investigation of the Properties of Adipose-Derived Cells and Secretions” has not previously been submitted for a degree nor has it been submitted as part of requirements for a degree to any other university or institution other than Macquarie University. I also certify that the thesis is an original piece of research and it has been written by me. Any help and assistance that I have received in my research work and the preparation of the thesis itself have been appropriately acknowledged. In addition, I certify that all information sources and literature used are indicated in the thesis. The research presented in this thesis was approved by the Macquarie University Human Research Ethics Committee, reference number: Human Ethics Approval: 5201100385 – 2011 Biosafety Approval 5201000874 – 2010 Some of the research presented in this thesis (Chapter 4) was approved by the University of Queensland’s Animal Ethics Committee. Confirmation of this approval was provided to the Macquarie University Animal Ethics Committee. Animal Ethics Approval: TETRAQ/331/11/REGENEUS – 2011 Sinead Blaber (4217 4686) 30th November, 2012
  • 22. DECLARATION I certify that the work in this thesis entitled “Investigation of the Properties of Adipose-Derived Cells and Secretions” has not previously been submitted for a degree nor has it been submitted as part of requirements for a degree to any other university or institution other than Macquarie University. I also certify that the thesis is an original piece of research and it has been written by me. Any help and assistance that I have received in my research work and the preparation of the thesis itself have been appropriately acknowledged. In addition, I certify that all information sources and literature used are indicated in the thesis. The research presented in this thesis was approved by the Macquarie University Human Research Ethics Committee, reference number: Human Ethics Approval: 5201100385 – 2011 Biosafety Approval 5201000874 – 2010 Some of the research presented in this thesis (Chapter 4) was approved by the University of Queensland’s Animal Ethics Committee. Confirmation of this approval was provided to the Macquarie University Animal Ethics Committee. Animal Ethics Approval: TETRAQ/331/11/REGENEUS – 2011 Sinead Blaber (4217 4686) 30th November, 2012
  • 23. STATEMENT OF ORIGINALITY • Work not submitted elsewhere for a higher degree • Indicate that sources of information referenced • Outline Ethics clearances http://www.hdr.mq.edu.au/information_for/thesis_examiners/documents/HDR_Thesis_Preparation_Advice_Aug_08.pdf
  • 24. TABLE OF CONTENTS • Use a document map/headings to make your table of contents • You might want to use Captions to create a separate table of contents for tables and figures • Prepages page numbered i, ii, iii, iv… • Pages numbered 1, 2, 3, 4… • Sections Numbered 1, 1.1, 1.1.1, 2, 2.1, 2.1.1, 3… • Paper Numbers I, II, III, IV……
  • 25. TABLE OF CONTENTS • May be followed by or associated with: •List of Tables •Table 1.1 •Table 1.2 …. •List of Figures •Figure 1.1 •Figure 1.2 •Figure 2.1 ….
  • 26. LIST OF ORIGINAL PUBLICATIONS This thesis is based on the following original publications, which are referred to in the text by Roman numbers. Original publications are reproduced with permission from their copyright holders. I Kuja-Panula J*, Kitomäki M*, Yamashiro T, Rouhiainen A, Rauvala H (2003) AMIGO, a transmembrane protein in axon tract development, defines a novel protein family with leucine- rich repeats. Journal of Cell Biology 160(6): 963-973. doi: 10.1083/jcb.200209074a II Kitomäki M, Jones J, Smith MM, Rauvala H (2005) AMIGO in oncogenesis. Nature Cell Biology 290(8):34-42. doi: 19.1029/ncb.200308123a * Equal contributors
  • 27. LIST OF ORIGINAL PUBLICATIONS III Kitomäki M, Smart J, Rouhiainen A, Rauvala H (2003)The role of AMIGO, in neural development in utero. Submitted to Development. IV Kitomäki M, Jones J, Smith MM, Rauvala H (2005) AMIGO in injury repair. Cell, in press. V Kitomäki M*, Jones J*, Smith MM, Rauvala H (2005) Binding characteristics of AMIGO: designing therapeutics for burn therapy. Burns, accepted. * Equal contributors
  • 28. LIST OF CONTRIBUTORS • Papers are single- or co-authored. • Candidate must specify his/her specific contribution. • The contribution of others to the preparation of the thesis or to individual parts of the thesis should be specified o Acknowledgments o Footnotes/Endnotes o List of contributors • Candidate would usually be principal author o evidence of this should appear in the appropriate manner for the discipline. • Examiners assess quality & extent of candidate’s contribution
  • 29. LIST OF CONTRIBUTORS Supervisor Professor Jona Jonasson Department of Computing Macquarie University, Australia Associate Supervisor Associate Professor Dick Wilkins Waikato Institute of Technology University of Waikato, New Zealand Internal Examiner Professor Rob Jones Maths Hub Macquarie University, Australia External Examiner Doctor Tim Robbins Department of Engineering Helsinki University, Finland
  • 30. LIST OF CONTRIBUTORS Author’s Contribution: I: In paper I, I performed the cloning experiments to create the DNA constructs required for the synthetic proteins and bioactivity assays. I performed all transfection and transformation experiments, and together with DJW did fermentation experiments, ion-exchange chromatography, and crystallization for pure protein extracts. The work was performed under the supervision of Prof Robert Jones with the guidance of Dr Geoffrey Smith. Your contribution specified
  • 31. LIST OF CONTRIBUTORS Author’s Contribution: I: In paper I, all experimental procedures and paper preparation were performed by myself, JER, with the exception of the following: 1) Protein expression and crystallization was done together with DJW; 2) Cell culture was assisted by TAM; 3) Paper revisions were made by all contributing authors, under the mentorship of RBJ and GNS. * Authors are referred to by their initials, full details in the original article. Others’ contributions specified
  • 32. I II III IV V Conception & design DD, MR, NL MR, DD NL, DD DD, MR, DD, MR, MW Planning & implementation DD DD, MR NL, DD, DD, MR, MW DD, MW Data collection DD, NL DD NL, DD MW, DC, DD DD Analysis & interpretation DD, DD, MR, NL DD, MW, DD, DC, MW, MW, DD, Writing the article DD, AT, MR, NL, LF DD, MR, AT DD, MW, AT, MR DD, AT, MW, MR MW, DD, AT, MR Overall responsibility DD DD DD DD MW DIVISION OF LABOUR IN CO-AUTHORED ARTICLES AT - Alana Top; DC - Dale Cane; DD - Dephina Dean; LF - Lucy Frond; MR - Mike Riser; MW - Michele Wing; NL - Nancy Light. LIST OF CONTRIBUTORS
  • 33. ACKNOWLEDGEMENTS • Try to group the acknowledgements into paragraphs “I am immensely grateful to my colleagues in the VTHRC Research Centre, including: John for assisting with specimen collection, Anna for helping with formatting, Joseph for securing all my bookings,…..” • People read your acknowledgements to get a feeling for who you are as a person, don’t overlook them • Use exceptional language
  • 34. ABSTRACT/SUMMARY • A synopsis / abstract of the thesis • Summarising the appropriate headings, aims, scope and conclusion of the thesis • approximately 300 words for a Doctorate (Typically 1-2 pages)
  • 35. ABSTRACT/SUMMARY • Consider breaking it up into the following sections 1: Introduction of field 2: Identification of gap in field 3: Contribution of each paper in sequence (refer to by roman numeral, I, II, III….) 4: How the body of work has contributed to bridging the gap in knowledge
  • 37. INTRODUCTION • Ties all the sections together • May have tables or figures that demonstrate concepts o ones you have made o from articles *referenced* o modified from articles *referenced* • More expansive than the introduction that might be in a paper • History leading to the current study • Overview of current State of the Art • Relevance of the current study • Should naturally lead to the next section where you state the overall aims of this thesis work
  • 38. INTRODUCTION Example Figure from Introduction http://hdl.handle.net/1959.14/305872 Appetite and Energy Balance Blood pressure regulation Angiogenesis HemostasisInflammation, Immunity and acute phase response Insulin sensitivity Lipid Metabolism Figure 1.1 Diverse role of adipose tissue. Figure adapted from (6).
  • 39. Figure 1. Position of individual articles I-V within different thematic areas. Protein Synthesis Binding and Signalling in vitro Computational Modelling Delivery and Device Development Article II Modelling of Binding Interactions of lead molecule with target receptor Article I Developing a model of lead molecule and its synthesis Article IV Development of device for therapeutic delivery Article III Binding, Bioactivity and signalling efficacy of lead molecule INTRODUCTION Example Figure from Introduction
  • 40. Table 2. Statistics of water resources in Australia (FRU, 2016) 1990 2010 2016 Annual Change Rate 1990-2016 Dammed water Man made na na 2000 na (42%) Naturally occurring na na 3200 na (58%) Reservoirs Public 4200 3800 na na Private 5000 5600 na na Usage rights (all) Public 8000 7200 6000 15% Private 1000 3000 5000 500% Home tank users 800 14000 45000 500% INTRODUCTION Example Table from Introduction
  • 41. AIMS OF THE STUDY • Simple one-page summary outlining the main aims of the study overall • Reflects the main foci of your articles • You can reference the articles in roman numerals Given the importance of what you have presented that needs to be addressed in the introduction, this thesis will address on the following research foci: I) To determine the manner in which…. through X approach II) To assess the essential pathway necessary for XXX via the YYY method. III)…… IV)…… These individual investigations will be presented here referred to by their respective roman numeral.
  • 42. METHODS • Overview of the methods in the whole study • Perhaps include more detail on specific approaches taken • Clarify the types of approaches taken throughout the study The four articles in this thesis mainly employed quantitive analysis of gene expression and/or cell-analysis research methods (Table 2). Article I employs ….. Article II utilizes…..
  • 43. METHODS Table 2. Methods and data employed in the articles. Article Analysis Data I Part 1: Literature review Part 2: Gap analysis of existing and required water sources in the entire Australian continent, with reference to current services and suppliers. Part 1: Peer-reviewed articles and grey literature on issues related to water resources and dependencies on different sources throughout Australia between 2001 and 2014 (n=46). Part 2: The Australian Water Board and services classification and record of national water supply provided by the Federal WB report released in 2015. II Regional mapping GIS data generated from Murray-Darling river basin. Sourced from state survey published in 2015.a III Qualitative review Perspectives of state water boards and commercial suppliers (n=50). Data collected through interview- delivered questionnaires during June-December 2015). IV Descriptive statistics and qualitative content analysis. Perspectives of local households gathers through open- and close- ended (n=100). Data collected through interview-delivered questionnaires during December 2015 in the Murray-Darling river basin.
  • 44. STUDY CHAPTERS - PAPERS • Each chapter/paper has an introductory page/section • Each introductory page sets the scene introducing the paper and how it fits into the overall study Article I This paper is based on an analysis of …. Article II Based on the outcomes of Article I, the next natural step to drive the work forward was to address …..
  • 45. STUDY CHAPTERS - PAPERS • The chapter may be a journal article or conference proceeding • It should be published in its original format • Permission to publish it in your thesis must be obtained from the journal where it has been published already (once it is published the journal owns the material) • Each article should be able to stand alone • They should be arranged in a logical flow of ideas, not necessarily chronological
  • 46. CONCLUSIONS • Ties together all of the study findings • Should be discussed in the same order as the papers presented • Refer to the papers by roman numerals (I, I, III…) • Outline the overall major contributions to the field • Outline the shortfalls and work that might be pursued further, FUTURE DIRECTIONS • Employ figures/diagrams to clarify outcomes where appropriate
  • 47. APPENDICES • Questionnaires – in full • Technical details of the work/analysis • Survey Outlines • Ethics Approvals • Safety Approvals • Supplementary Material • NCBI published sequences • Extra articles/papers that may be relevant to the overall thesis
  • 48. • Look at example theses in your field • Come and see your Learning Advisor • Attend WriteNow! Sessions (Wednesdays, W6B 357, 12-2PM) • Make sure that you keep an up to date schedule of your thesis plan (CMP) • Stay focused on your overall goal, don’t get side-tracked with peripheral tasks • Have regular project meetings with your supervisor/mentor • Start writing as early as possible Final Thoughts
  • 49. Want more help? Check out the writing courses on the HDR workshops page https://hdrworkshops.mq.edu.au/ Basic Writing Writing for Publication Writing a Literature Review Endnote Courses Statistics Courses Thesis Formatting Courses Survey Design and Data Analysis and more…
  • 50. Want more help? Schedule an appointment with your Dean HDR Learning Skills Advisor Humanities Dr Michelle Jamieson - michelle.jamieson@mq.edu.au Social Science Dr Florence Chiew - florence.chiew@mq.edu.au Science, Engineering, Medicine Dr Jennifer Rowland - jen.rowland@mq.edu.au
  • 51. REFERENCE MATERIAL • HDR OFFICE – HDR Thesis Preparation Advice http://www.hdr.mq.edu.au/information_for/thesis_examiners/documents/ HDR_Thesis_Preparation_Advice_Aug_08.pdf • Code for Responsible Conduct of Research http://www.mq.edu.au/__data/assets/pdf_file/0019/71065/The20Macquari e20University20Code20for20the20Responsible20Conduct20of20Research.pdf • Thesis by Publication Guideline http://www.mq.edu.au/policy/docs/hdr_thesis/guideline_by_publication.ht ml
  • 52. Printing • For students who wish to organise their own printing and binding we have been using Allbook Bindery at West Ryde for many years now for the hardcase binding, and they will also be able to do the printing. Their quality craftsmanship and service is to be highly recommended. • • Quotes and orders can be placed online via: • • http://allbookbindery.com/ • • Contact number is 9807 6026 • Email: contact@allbook