This document discusses cardiomyopathy, which is a disease of the heart muscle. Cardiomyopathy is a heterogeneous group of diseases associated with mechanical and/or electrical dysfunction of the myocardium. There are three primary patterns: hypertrophic, dilated, and restrictive. Symptoms include dyspnea, fatigue, arrhythmia, chest pain, and edema. Diagnosis involves physical exam, labs, ECG, echocardiogram, heart catheterization, and endomyocardial biopsy. Causes can be genetic, inflammatory, toxic, metabolic, or idiopathic. Treatment focuses on symptoms and transplantation may be required in some cases.

1. Prof Dr J Prabhakar Patro
Professor of Medicine
The Oxford Medical College Hospital,
Bengaluru.
drpatrojp@gmail.com

2.  Cardiomyopathy
 Is disease of heart muscle

3.  A heterogenous group of diseases of
myocardium
associated with Mechanical and/or electrical
dysfunction that usually exhibit
Inappropriate Ventricular
Hypertrophy or dilatation due to variety of
causes that frequently are genetic.

4. 3 Primary patterns
 1. Hypertrophic
 2. Dilated
 3. Restrictive

5.  Dyspnea
 Fatigue
 Arrhythmia
 Chest pain
 Oedema

6.  Physical exam : S3, Rales,
hepatomegaly,oedema
 Labs: Elevated BNP, Low serum Sodium
 ECG: BBB, old MI, Arrhythmia
 ECHO
 L Heart Cath
 Endomyocardial Biopsy

8.  Commonest type
 Inherited, usually AD.

9.  Pathophysiology:
 LVH: elaborate and inappropriate

18.  Enlarged LV
+
 Decreased LVEF

20.  Inflammatory:
1. Infective: Viral,parasite(T.cruzi)
2. Non infective: Collagen disease
 Toxic: Alcoholic
 Metabolic : nutritional deficiency:
Beri beri
 Inherited
 Idiopathic
 Miscellaneous

23. Definition:
 The ventricles are ‘stiff’  ventricular
filling is impaired.
 Rare condition

24. Pathophysiology
Impaired LV filling LA pressure rises
LA hypertrophy LA dilatation
Atrial Fibrillation
Usually both Atria are enlarged
Cardiac output is preserved till late in the
disease.

25.  Infiltrative(between Myocytes)
 Storage( within Myocytes)
 Fibrotic: Radiation,Scleroderma
 Endomyocardial
 Overlap with other cardiomyopathies
 Idiopathic

27. Diagnosis
 Echocardiogrphy, MRI
 Endomyocardial biopsy

28.  Treatment:
 Symptomatic.
 Transplantation

29.  Please send suggestions/comments to
drpatrojp@gmail.com