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March	
  19th
	
  2014	
  
	
  
Dear	
  Patient	
  Group	
  Representative,	
  	
  
	
  
As	
  announced	
  during	
  Prosensa’s	
  2013	
  Earnings	
  Call	
  on	
  March	
  18th
,	
  Prosensa	
  will	
  present	
  a	
  status	
  
update	
  on	
  drisapersen	
  and	
  its	
  follow-­‐on	
  compounds	
  in	
  a	
  patient	
  focused	
  webinar	
  hosted	
  by	
  United	
  
Parent	
  Projects	
  Muscular	
  Dystrophy	
  (UPPMD)	
  on	
  Tuesday	
  25th	
  of	
  March	
  at	
  1	
  PM	
  ET	
  /	
  6	
  PM	
  CET.	
  This	
  
webinar	
  aims	
  to	
  keep	
  the	
  patient	
  community	
  informed	
  on	
  the	
  status	
  of	
  Prosensa’s	
  DMD	
  programs	
  
and	
  to	
  enable	
  all	
  patient	
  organizations	
  and	
  their	
  members	
  to	
  submit	
  questions.	
  The	
  webinar	
  will	
  be	
  
presented	
  by	
  Giles	
  Campion	
  MD,	
  Chief	
  Medical	
  Officer	
  and	
  Senior	
  Vice-­‐President	
  R&D	
  of	
  Prosensa	
  
and	
  he	
  will	
  be	
  joined	
  by	
  the	
  following	
  guest	
  speakers:	
  	
  
-­‐ Craig	
  Campbell	
  MD	
  MSc	
  FRCPC,	
  Head	
  of	
  Section	
  of	
  Pediatric	
  Neurology	
  at	
  London	
  Health	
  
Sciences	
  Centre,	
  Associate	
  Professor	
  at	
  Shulich	
  School	
  of	
  Medicine	
  of	
  Western	
  University,	
  
Associate	
  Scientist	
  at	
  Child	
  Health	
  Research	
  Institute	
  	
  
-­‐ Craig	
  M.	
  McDonald	
  MD,	
  Professor	
  and	
  Chair	
  of	
  Physical	
  Medicine	
  &	
  Rehabilitation,	
  Professor	
  
of	
  Pediatrics	
  at	
  University	
  of	
  California	
  Davis	
  School	
  of	
  Medicine	
  	
  
	
  
To	
  Participate:	
  
1.	
  	
  	
  	
  	
  Visit	
  www.ReadyTalk.com	
  	
  and	
  use	
  participant	
  code	
  9449985.	
  (Be	
  sure	
  to	
  test	
  your	
  computer	
  
beforehand)	
  
2.	
  	
  	
  	
  	
  Audio	
  Dial-­‐In	
  Information:	
  
-­‐	
  U.S.	
  &	
  Canada:	
  Dial	
  866.740.1260	
  and	
  use	
  the	
  Access	
  Code	
  9449985	
  
-­‐	
  Outside	
  the	
  U.S.	
  and	
  Canada:	
  Lookup	
  your	
  number	
  (use	
  code	
  9449985)	
  	
  
	
  
As	
  you	
  may	
  know,	
  we	
  issued	
  a	
  press	
  release	
  on	
  March	
  17th
	
  announcing	
  48-­‐week	
  data	
  from	
  a	
  U.S.	
  
phase	
  II	
  placebo-­‐controlled	
  study	
  of	
  drisapersen	
  in	
  51	
  DMD	
  boys,	
  which	
  is	
  available	
  on	
  our	
  website	
  at	
  
http://ir.prosensa.eu/releases.cfm.	
  Additionally,	
  Prosensa	
  provided	
  Full	
  Year	
  2013	
  Financial	
  Results	
  &	
  
a	
  Corporate	
  Update	
  on	
  March	
  18th
,	
  and	
  the	
  recording	
  can	
  be	
  accessed	
  on	
  our	
  website	
  at	
  
http://ir.prosensa.eu/events.cfm.	
  	
  
	
  
If	
  you	
  have	
  any	
  questions	
  on	
  these	
  communications	
  or	
  any	
  other	
  topic	
  related	
  to	
  our	
  DMD	
  portfolio	
  
that	
  you	
  would	
  like	
  Prosensa	
  to	
  address	
  during	
  the	
  webinar,	
  you	
  may	
  submit	
  these	
  in	
  advance	
  to	
  
UPPMD	
  at	
  UPPMD@euronet.nl.	
  Please	
  put	
  ‘Prosensa	
  webinar	
  question’	
  in	
  the	
  subject	
  line.	
  We	
  will	
  
try	
  to	
  answer	
  as	
  many	
  questions	
  as	
  possible	
  during	
  the	
  webinar,	
  and	
  those	
  that	
  we	
  cannot	
  address	
  
during	
  the	
  call,	
  will	
  receive	
  a	
  response	
  at	
  a	
  later	
  time.	
  
	
  	
  
For	
  any	
  other	
  questions,	
  please	
  do	
  not	
  hesitate	
  to	
  contact	
  me.	
  	
  
	
  
With	
  kindest	
  regards,	
  
Claire	
  Leyten	
  
	
  
Claire	
  C.M.	
  Leyten,	
  PharmD	
  MBA	
  
Manager	
  Patient	
  Group	
  Relations	
  
E:	
  patientinfo@prosensa.nl	
  	
  	
  
Prosensa	
  J.H.	
  Oortweg	
  21	
  ,	
  2333	
  CH	
  Leiden,	
  The	
  Netherlands	
  	
  
www.prosensa.com	
  

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Announcement of uppmd webinar 25 march 2014

  • 1.                                                                               March  19th  2014     Dear  Patient  Group  Representative,       As  announced  during  Prosensa’s  2013  Earnings  Call  on  March  18th ,  Prosensa  will  present  a  status   update  on  drisapersen  and  its  follow-­‐on  compounds  in  a  patient  focused  webinar  hosted  by  United   Parent  Projects  Muscular  Dystrophy  (UPPMD)  on  Tuesday  25th  of  March  at  1  PM  ET  /  6  PM  CET.  This   webinar  aims  to  keep  the  patient  community  informed  on  the  status  of  Prosensa’s  DMD  programs   and  to  enable  all  patient  organizations  and  their  members  to  submit  questions.  The  webinar  will  be   presented  by  Giles  Campion  MD,  Chief  Medical  Officer  and  Senior  Vice-­‐President  R&D  of  Prosensa   and  he  will  be  joined  by  the  following  guest  speakers:     -­‐ Craig  Campbell  MD  MSc  FRCPC,  Head  of  Section  of  Pediatric  Neurology  at  London  Health   Sciences  Centre,  Associate  Professor  at  Shulich  School  of  Medicine  of  Western  University,   Associate  Scientist  at  Child  Health  Research  Institute     -­‐ Craig  M.  McDonald  MD,  Professor  and  Chair  of  Physical  Medicine  &  Rehabilitation,  Professor   of  Pediatrics  at  University  of  California  Davis  School  of  Medicine       To  Participate:   1.          Visit  www.ReadyTalk.com    and  use  participant  code  9449985.  (Be  sure  to  test  your  computer   beforehand)   2.          Audio  Dial-­‐In  Information:   -­‐  U.S.  &  Canada:  Dial  866.740.1260  and  use  the  Access  Code  9449985   -­‐  Outside  the  U.S.  and  Canada:  Lookup  your  number  (use  code  9449985)       As  you  may  know,  we  issued  a  press  release  on  March  17th  announcing  48-­‐week  data  from  a  U.S.   phase  II  placebo-­‐controlled  study  of  drisapersen  in  51  DMD  boys,  which  is  available  on  our  website  at   http://ir.prosensa.eu/releases.cfm.  Additionally,  Prosensa  provided  Full  Year  2013  Financial  Results  &   a  Corporate  Update  on  March  18th ,  and  the  recording  can  be  accessed  on  our  website  at   http://ir.prosensa.eu/events.cfm.       If  you  have  any  questions  on  these  communications  or  any  other  topic  related  to  our  DMD  portfolio   that  you  would  like  Prosensa  to  address  during  the  webinar,  you  may  submit  these  in  advance  to   UPPMD  at  UPPMD@euronet.nl.  Please  put  ‘Prosensa  webinar  question’  in  the  subject  line.  We  will   try  to  answer  as  many  questions  as  possible  during  the  webinar,  and  those  that  we  cannot  address   during  the  call,  will  receive  a  response  at  a  later  time.       For  any  other  questions,  please  do  not  hesitate  to  contact  me.       With  kindest  regards,   Claire  Leyten     Claire  C.M.  Leyten,  PharmD  MBA   Manager  Patient  Group  Relations   E:  patientinfo@prosensa.nl       Prosensa  J.H.  Oortweg  21  ,  2333  CH  Leiden,  The  Netherlands     www.prosensa.com