SlideShare a Scribd company logo
1 of 34
ACNE
By Anjita Khadka
Masters in Clinical Pharmacy
2nd semester
ACNE
• a skin condition that occurs when your hair
follicles become plugged with oil and dead
skin cells.
• often causes:
– whiteheads
– blackheads or pimples, and
– usually appears on the face, forehead, chest,
upper back and shoulders
• Also called as acne vulgaris.
• most common among teenagers, though it
affects people of all ages.
PREVALENCE
• As high as 95% with a 20 % to 35% prevalence
of moderate to severe acne.
• Most prevalent in USA, UK, and Australia.
• Estimates reveal a 30 % increase in the
number of people turning towards
homeopathy for the treatment of their Acne
vulgaris and other skin problems globally.
ACNE SIGNS AND SYMPTOMS
• vary depending on the severity of your
condition:
– Whiteheads (closed plugged pores)
– Blackheads (open plugged pores)
– Small red, tender bumps (papules)
– Pimples (pustules), which are papules with pus at
their tips
– Large, solid, painful lumps beneath the surface of
the skin (nodules)
– Painful, pus-filled lumps beneath the surface of
the skin (cystic lesions)
CAUSES
• Excess oil production
• Hair follicles clogged by oil and dead skin cells
• Bacterial infection (Propionibacterium acnes)
• Excess activity of a type of hormone
(androgens)
RISK FACTORS
• Genetic
• Obesity: hyperandrogenism
• A significant positive family history of acne has
been demonstrated especially when acne is
found in:
– Twins
– Mother
– First degree relative
– Multiple family members
AGGRAVATING FACTORS
• Smoking
• Stress
• Facial therapy or, salon facial massage
• High glycemic loads diet
• Milk and milk products
• Tight cloths/ head bands
TYPES OF ACNE
• Acne conglobata
• Occupational acne
• Cosmetic acne
• Drug-induced acne
• Infantile acne
• Late onset acne
• Acne excoriee
• Acne fulminans
• Post-facial massage acne
Types of acne
1. Acne conglobata:
 Severe form
 intercommunicating
abscesses, cysts and sinuses
loaded with serosanguinous
fluid or, pus.
 Comedines-multiparous
 Lesions take months to heal
and on healing leave behind
deep pitted or, hypertrophic
scars, joined by keloidal
bridges.
 Occlusion syndrome
Types of acne
2. Occupational acne:
• caused by exposure to industrial
chemicals.
• Predominantly comedones
• Suspected in:
-unusal sites of involvement
e.g. forearms
-unusal age e.g. middle age
males
Types of acne
3. Cosmetic acne:
• Eruption seen in women using
cosmetics,especially oil based ones.
• Almost always comedones
• Lesion frequently on the chin
4. Drug –induced acne:
• steroids, androgens, anabolic steroids,
OCPs, anti-TB drugs,iodides, bromides and
anticonvulsant can cause acneiform
eruption.
• lesions- monomorphic, consisting of
papules and pustules.
• Trunk especially back and face may be
involved.
Types of acne
5. Infantile acne:
• due to presence of maternal hormones
in the child.
• higher in males.
• May present at birth and may last for
upto 3 yrs.
•Lesions similar to those of adloscent
acne.
6. Late onset acne:
• Acne with onset after 25 years old.
•Predominantly as deep seated,
persistent lesions on lower half of
face.
•Exclude underlying androgen
secretion pathology, especially
polycystic ovarian syndrome.
Types of acne
7. Acne excoriee:
• seen in young girls, who
excessively pick their mild acne.
• results in discrete excoriations
on the face, while comodones and
papules are few and far in
between.
8. Acne fulminans:
• acute onset
• Presents as crusted, ulcerated
lesions.
• associated with fever, myalgia
and arthralgia.
Types of acne
9. Post-facial massage acne:
• facial massage may be followed (3-6 wks later) by an
acneiform eruption in about 30% patient.
• indolent deep seated nodules with very few ( or no)
comedones.
• heal with hyperpigmentation after several weeks.
• predominantly on cheeks, along the mandible.
DIAGNOSIS
LABORATORY EXAMINATIONS
DIFFERENTIAL DIAGNOSIS
PRINCIPLE MANAGEMENT
TREATMENT
PHARMACOLOGICAL TREATMENT
• Comedonal acne:
– 1st line treatment: Topical retinoid
– Usually, initiated with the lowest strength retenoid
to minimize redness and dryness.
– Strength may be increased if needed.
– Alternative therapies: Benzoyl peroxide, azeleic
acid or, salicylic acid.
• Papular/pustular Acne:
– Mild disease:
• 1st line therapy: a topical retinoid + topical antibiotic,
Benzoyl peroxide may be added.
• Alternative therapy: Azaleic acid
– Moderate to severe disease:
• same 1st line therapy as mild disease.
– Severe disease:
• 1st line therapy: oral antibiotics+ a topical retinoid +
Benzoyl peroxide gel or wash.
• Alternative therapy: switching to another type of
topical retinoid + another type of antibiotic + Benzoyl
peroxide.
• Nodular acne:
– 1st line therapy:
• oral antibiotics + topical retinoid + Benzoyl peroxide
– If still persistant, may need a referral to use of oral
Isotretinoin therapy.
ORAL ANTIBIOTICS
• Oral antibiotics and typical doses for Acne:
– Doxycycline : 50-100 mg BID
– Erythromycin : 250-500mg BID
– Minocycline: 50-100mg BID
– Tetracycline: 250-500mg BID
Acne
Acne
Acne

More Related Content

What's hot (20)

Acne
AcneAcne
Acne
 
Dandruff
DandruffDandruff
Dandruff
 
Dermatitis ppt
Dermatitis pptDermatitis ppt
Dermatitis ppt
 
Dermatitis slide
Dermatitis slideDermatitis slide
Dermatitis slide
 
4. Acne vulgaris
4. Acne vulgaris4. Acne vulgaris
4. Acne vulgaris
 
Acne
AcneAcne
Acne
 
Psoriasis
PsoriasisPsoriasis
Psoriasis
 
prickly heat
prickly heatprickly heat
prickly heat
 
Psoriasis
PsoriasisPsoriasis
Psoriasis
 
Dandruff
Dandruff Dandruff
Dandruff
 
Dermatitis
DermatitisDermatitis
Dermatitis
 
Acne disorders
Acne disordersAcne disorders
Acne disorders
 
Dermatitis
DermatitisDermatitis
Dermatitis
 
Dandruff
DandruffDandruff
Dandruff
 
Acne
AcneAcne
Acne
 
Impetigo
ImpetigoImpetigo
Impetigo
 
Acne vulgaris
Acne vulgarisAcne vulgaris
Acne vulgaris
 
Acne vulgaris
Acne vulgarisAcne vulgaris
Acne vulgaris
 
Psoriasis
PsoriasisPsoriasis
Psoriasis
 
Vitiligo
VitiligoVitiligo
Vitiligo
 

Similar to Acne

Acne Y3 B.pptx
Acne Y3 B.pptxAcne Y3 B.pptx
Acne Y3 B.pptxsamirich1
 
Acne Vulgaris - Pharmacotherapy
Acne Vulgaris - PharmacotherapyAcne Vulgaris - Pharmacotherapy
Acne Vulgaris - PharmacotherapyAreej Abu Hanieh
 
dermatology. disorders of sebaceous and sweat glands.(dr.faraydwn)
dermatology. disorders of sebaceous and sweat glands.(dr.faraydwn)dermatology. disorders of sebaceous and sweat glands.(dr.faraydwn)
dermatology. disorders of sebaceous and sweat glands.(dr.faraydwn)student
 
ACNE VULGARIS.pptx
ACNE VULGARIS.pptxACNE VULGARIS.pptx
ACNE VULGARIS.pptxvishwarath
 
Integumentary disorders 1
Integumentary disorders 1Integumentary disorders 1
Integumentary disorders 1Richie Chacko
 
Skin conditions of surgical Importance.pptx
Skin conditions of surgical Importance.pptxSkin conditions of surgical Importance.pptx
Skin conditions of surgical Importance.pptxDakaneMaalim
 
Psoriasis & Acne vulgaris.pptx (Integumentary System)
Psoriasis & Acne vulgaris.pptx (Integumentary System)Psoriasis & Acne vulgaris.pptx (Integumentary System)
Psoriasis & Acne vulgaris.pptx (Integumentary System)PatelVedanti
 
Common Dermatological Problems
Common Dermatological ProblemsCommon Dermatological Problems
Common Dermatological ProblemsMustafa AlWard
 
Skin Pigmentation disorders and its management .pptx
Skin Pigmentation disorders and its management .pptxSkin Pigmentation disorders and its management .pptx
Skin Pigmentation disorders and its management .pptxJagruti Marathe
 
Integumentary disorders 2
Integumentary disorders 2Integumentary disorders 2
Integumentary disorders 2Richie Chacko
 

Similar to Acne (20)

Acne Y3 B.pptx
Acne Y3 B.pptxAcne Y3 B.pptx
Acne Y3 B.pptx
 
Acne Vulgaris - Pharmacotherapy
Acne Vulgaris - PharmacotherapyAcne Vulgaris - Pharmacotherapy
Acne Vulgaris - Pharmacotherapy
 
dermatology. disorders of sebaceous and sweat glands.(dr.faraydwn)
dermatology. disorders of sebaceous and sweat glands.(dr.faraydwn)dermatology. disorders of sebaceous and sweat glands.(dr.faraydwn)
dermatology. disorders of sebaceous and sweat glands.(dr.faraydwn)
 
Acne vulgaris
Acne vulgarisAcne vulgaris
Acne vulgaris
 
Skin and skin diseases
Skin and skin diseasesSkin and skin diseases
Skin and skin diseases
 
ACNE VULGARIS.pptx
ACNE VULGARIS.pptxACNE VULGARIS.pptx
ACNE VULGARIS.pptx
 
Integumentary disorders 1
Integumentary disorders 1Integumentary disorders 1
Integumentary disorders 1
 
Skin conditions of surgical Importance.pptx
Skin conditions of surgical Importance.pptxSkin conditions of surgical Importance.pptx
Skin conditions of surgical Importance.pptx
 
Acne vulgaris
Acne vulgarisAcne vulgaris
Acne vulgaris
 
Psoriasis & Acne vulgaris.pptx (Integumentary System)
Psoriasis & Acne vulgaris.pptx (Integumentary System)Psoriasis & Acne vulgaris.pptx (Integumentary System)
Psoriasis & Acne vulgaris.pptx (Integumentary System)
 
Common Dermatological Problems
Common Dermatological ProblemsCommon Dermatological Problems
Common Dermatological Problems
 
Acne Vulgaris
Acne VulgarisAcne Vulgaris
Acne Vulgaris
 
Acne final
Acne finalAcne final
Acne final
 
Acne final
Acne finalAcne final
Acne final
 
Acne vulgaris
Acne vulgaris Acne vulgaris
Acne vulgaris
 
Acne vulgaris.pptx
Acne vulgaris.pptxAcne vulgaris.pptx
Acne vulgaris.pptx
 
Skin Pigmentation disorders and its management .pptx
Skin Pigmentation disorders and its management .pptxSkin Pigmentation disorders and its management .pptx
Skin Pigmentation disorders and its management .pptx
 
acne vs rosacea.pptx
acne vs rosacea.pptxacne vs rosacea.pptx
acne vs rosacea.pptx
 
skins
skins skins
skins
 
Integumentary disorders 2
Integumentary disorders 2Integumentary disorders 2
Integumentary disorders 2
 

More from Anjita Khadka

Trade Related Aspects Of Intellectual Property Rights (TRIPS)
Trade Related Aspects Of Intellectual Property Rights (TRIPS)Trade Related Aspects Of Intellectual Property Rights (TRIPS)
Trade Related Aspects Of Intellectual Property Rights (TRIPS)Anjita Khadka
 
Non small cell lung cancer
Non small cell lung cancerNon small cell lung cancer
Non small cell lung cancerAnjita Khadka
 
Mechanism of drug absorption in git
Mechanism of drug absorption in gitMechanism of drug absorption in git
Mechanism of drug absorption in gitAnjita Khadka
 
Antiarrhythmic drugs
Antiarrhythmic drugsAntiarrhythmic drugs
Antiarrhythmic drugsAnjita Khadka
 

More from Anjita Khadka (6)

Trade Related Aspects Of Intellectual Property Rights (TRIPS)
Trade Related Aspects Of Intellectual Property Rights (TRIPS)Trade Related Aspects Of Intellectual Property Rights (TRIPS)
Trade Related Aspects Of Intellectual Property Rights (TRIPS)
 
Non small cell lung cancer
Non small cell lung cancerNon small cell lung cancer
Non small cell lung cancer
 
Mechanism of drug absorption in git
Mechanism of drug absorption in gitMechanism of drug absorption in git
Mechanism of drug absorption in git
 
Antiarrhythmic drugs
Antiarrhythmic drugsAntiarrhythmic drugs
Antiarrhythmic drugs
 
Gas chromatography
Gas chromatographyGas chromatography
Gas chromatography
 
Hemodialysis
HemodialysisHemodialysis
Hemodialysis
 

Recently uploaded

Call Girl in Chennai | Whatsapp No 📞 7427069034 📞 VIP Escorts Service Availab...
Call Girl in Chennai | Whatsapp No 📞 7427069034 📞 VIP Escorts Service Availab...Call Girl in Chennai | Whatsapp No 📞 7427069034 📞 VIP Escorts Service Availab...
Call Girl in Chennai | Whatsapp No 📞 7427069034 📞 VIP Escorts Service Availab...amritaverma53
 
Call 8250092165 Patna Call Girls ₹4.5k Cash Payment With Room Delivery
Call 8250092165 Patna Call Girls ₹4.5k Cash Payment With Room DeliveryCall 8250092165 Patna Call Girls ₹4.5k Cash Payment With Room Delivery
Call 8250092165 Patna Call Girls ₹4.5k Cash Payment With Room DeliveryJyoti singh
 
Russian Call Girls In Pune 👉 Just CALL ME: 9352988975 ✅❤️💯low cost unlimited ...
Russian Call Girls In Pune 👉 Just CALL ME: 9352988975 ✅❤️💯low cost unlimited ...Russian Call Girls In Pune 👉 Just CALL ME: 9352988975 ✅❤️💯low cost unlimited ...
Russian Call Girls In Pune 👉 Just CALL ME: 9352988975 ✅❤️💯low cost unlimited ...chanderprakash5506
 
Call Girls Mussoorie Just Call 8854095900 Top Class Call Girl Service Available
Call Girls Mussoorie Just Call 8854095900 Top Class Call Girl Service AvailableCall Girls Mussoorie Just Call 8854095900 Top Class Call Girl Service Available
Call Girls Mussoorie Just Call 8854095900 Top Class Call Girl Service AvailableJanvi Singh
 
Call Girls Kathua Just Call 8250077686 Top Class Call Girl Service Available
Call Girls Kathua Just Call 8250077686 Top Class Call Girl Service AvailableCall Girls Kathua Just Call 8250077686 Top Class Call Girl Service Available
Call Girls Kathua Just Call 8250077686 Top Class Call Girl Service AvailableDipal Arora
 
Circulatory Shock, types and stages, compensatory mechanisms
Circulatory Shock, types and stages, compensatory mechanismsCirculatory Shock, types and stages, compensatory mechanisms
Circulatory Shock, types and stages, compensatory mechanismsMedicoseAcademics
 
❤️ Chandigarh Call Girls☎️98151-579OO☎️ Call Girl service in Chandigarh ☎️ Ch...
❤️ Chandigarh Call Girls☎️98151-579OO☎️ Call Girl service in Chandigarh ☎️ Ch...❤️ Chandigarh Call Girls☎️98151-579OO☎️ Call Girl service in Chandigarh ☎️ Ch...
❤️ Chandigarh Call Girls☎️98151-579OO☎️ Call Girl service in Chandigarh ☎️ Ch...Rashmi Entertainment
 
Call Girls Bangalore - 450+ Call Girl Cash Payment 💯Call Us 🔝 6378878445 🔝 💃 ...
Call Girls Bangalore - 450+ Call Girl Cash Payment 💯Call Us 🔝 6378878445 🔝 💃 ...Call Girls Bangalore - 450+ Call Girl Cash Payment 💯Call Us 🔝 6378878445 🔝 💃 ...
Call Girls Bangalore - 450+ Call Girl Cash Payment 💯Call Us 🔝 6378878445 🔝 💃 ...gragneelam30
 
👉 Chennai Sexy Aunty’s WhatsApp Number 👉📞 7427069034 👉📞 Just📲 Call Ruhi Colle...
👉 Chennai Sexy Aunty’s WhatsApp Number 👉📞 7427069034 👉📞 Just📲 Call Ruhi Colle...👉 Chennai Sexy Aunty’s WhatsApp Number 👉📞 7427069034 👉📞 Just📲 Call Ruhi Colle...
👉 Chennai Sexy Aunty’s WhatsApp Number 👉📞 7427069034 👉📞 Just📲 Call Ruhi Colle...rajnisinghkjn
 
Chennai ❣️ Call Girl 6378878445 Call Girls in Chennai Escort service book now
Chennai ❣️ Call Girl 6378878445 Call Girls in Chennai Escort service book nowChennai ❣️ Call Girl 6378878445 Call Girls in Chennai Escort service book now
Chennai ❣️ Call Girl 6378878445 Call Girls in Chennai Escort service book nowtanudubay92
 
Call girls Service Phullen / 9332606886 Genuine Call girls with real Photos a...
Call girls Service Phullen / 9332606886 Genuine Call girls with real Photos a...Call girls Service Phullen / 9332606886 Genuine Call girls with real Photos a...
Call girls Service Phullen / 9332606886 Genuine Call girls with real Photos a...call girls hydrabad
 
Lucknow Call Girls Service { 9984666624 } ❤️VVIP ROCKY Call Girl in Lucknow U...
Lucknow Call Girls Service { 9984666624 } ❤️VVIP ROCKY Call Girl in Lucknow U...Lucknow Call Girls Service { 9984666624 } ❤️VVIP ROCKY Call Girl in Lucknow U...
Lucknow Call Girls Service { 9984666624 } ❤️VVIP ROCKY Call Girl in Lucknow U...Janvi Singh
 
ANATOMY AND PHYSIOLOGY OF RESPIRATORY SYSTEM.pptx
ANATOMY AND PHYSIOLOGY OF RESPIRATORY SYSTEM.pptxANATOMY AND PHYSIOLOGY OF RESPIRATORY SYSTEM.pptx
ANATOMY AND PHYSIOLOGY OF RESPIRATORY SYSTEM.pptxSwetaba Besh
 
7 steps How to prevent Thalassemia : Dr Sharda Jain & Vandana Gupta
7 steps How to prevent Thalassemia : Dr Sharda Jain & Vandana Gupta7 steps How to prevent Thalassemia : Dr Sharda Jain & Vandana Gupta
7 steps How to prevent Thalassemia : Dr Sharda Jain & Vandana GuptaLifecare Centre
 
Call Girls in Lucknow Just Call 👉👉 8875999948 Top Class Call Girl Service Ava...
Call Girls in Lucknow Just Call 👉👉 8875999948 Top Class Call Girl Service Ava...Call Girls in Lucknow Just Call 👉👉 8875999948 Top Class Call Girl Service Ava...
Call Girls in Lucknow Just Call 👉👉 8875999948 Top Class Call Girl Service Ava...Janvi Singh
 
💞 Safe And Secure Call Girls Coimbatore🧿 6378878445 🧿 High Class Coimbatore C...
💞 Safe And Secure Call Girls Coimbatore🧿 6378878445 🧿 High Class Coimbatore C...💞 Safe And Secure Call Girls Coimbatore🧿 6378878445 🧿 High Class Coimbatore C...
💞 Safe And Secure Call Girls Coimbatore🧿 6378878445 🧿 High Class Coimbatore C...dilbirsingh0889
 
(RIYA)🎄Airhostess Call Girl Jaipur Call Now 8445551418 Premium Collection Of ...
(RIYA)🎄Airhostess Call Girl Jaipur Call Now 8445551418 Premium Collection Of ...(RIYA)🎄Airhostess Call Girl Jaipur Call Now 8445551418 Premium Collection Of ...
(RIYA)🎄Airhostess Call Girl Jaipur Call Now 8445551418 Premium Collection Of ...TanyaAhuja34
 
Call Girls in Lucknow Just Call 👉👉8630512678 Top Class Call Girl Service Avai...
Call Girls in Lucknow Just Call 👉👉8630512678 Top Class Call Girl Service Avai...Call Girls in Lucknow Just Call 👉👉8630512678 Top Class Call Girl Service Avai...
Call Girls in Lucknow Just Call 👉👉8630512678 Top Class Call Girl Service Avai...soniyagrag336
 
Bhopal❤CALL GIRL 9352988975 ❤CALL GIRLS IN Bhopal ESCORT SERVICE
Bhopal❤CALL GIRL 9352988975 ❤CALL GIRLS IN Bhopal ESCORT SERVICEBhopal❤CALL GIRL 9352988975 ❤CALL GIRLS IN Bhopal ESCORT SERVICE
Bhopal❤CALL GIRL 9352988975 ❤CALL GIRLS IN Bhopal ESCORT SERVICErahuljha3240
 
Chennai Call Girls Service {7857862533 } ❤️VVIP ROCKY Call Girl in Chennai
Chennai Call Girls Service {7857862533 } ❤️VVIP ROCKY Call Girl in ChennaiChennai Call Girls Service {7857862533 } ❤️VVIP ROCKY Call Girl in Chennai
Chennai Call Girls Service {7857862533 } ❤️VVIP ROCKY Call Girl in Chennaikhalifaescort01
 

Recently uploaded (20)

Call Girl in Chennai | Whatsapp No 📞 7427069034 📞 VIP Escorts Service Availab...
Call Girl in Chennai | Whatsapp No 📞 7427069034 📞 VIP Escorts Service Availab...Call Girl in Chennai | Whatsapp No 📞 7427069034 📞 VIP Escorts Service Availab...
Call Girl in Chennai | Whatsapp No 📞 7427069034 📞 VIP Escorts Service Availab...
 
Call 8250092165 Patna Call Girls ₹4.5k Cash Payment With Room Delivery
Call 8250092165 Patna Call Girls ₹4.5k Cash Payment With Room DeliveryCall 8250092165 Patna Call Girls ₹4.5k Cash Payment With Room Delivery
Call 8250092165 Patna Call Girls ₹4.5k Cash Payment With Room Delivery
 
Russian Call Girls In Pune 👉 Just CALL ME: 9352988975 ✅❤️💯low cost unlimited ...
Russian Call Girls In Pune 👉 Just CALL ME: 9352988975 ✅❤️💯low cost unlimited ...Russian Call Girls In Pune 👉 Just CALL ME: 9352988975 ✅❤️💯low cost unlimited ...
Russian Call Girls In Pune 👉 Just CALL ME: 9352988975 ✅❤️💯low cost unlimited ...
 
Call Girls Mussoorie Just Call 8854095900 Top Class Call Girl Service Available
Call Girls Mussoorie Just Call 8854095900 Top Class Call Girl Service AvailableCall Girls Mussoorie Just Call 8854095900 Top Class Call Girl Service Available
Call Girls Mussoorie Just Call 8854095900 Top Class Call Girl Service Available
 
Call Girls Kathua Just Call 8250077686 Top Class Call Girl Service Available
Call Girls Kathua Just Call 8250077686 Top Class Call Girl Service AvailableCall Girls Kathua Just Call 8250077686 Top Class Call Girl Service Available
Call Girls Kathua Just Call 8250077686 Top Class Call Girl Service Available
 
Circulatory Shock, types and stages, compensatory mechanisms
Circulatory Shock, types and stages, compensatory mechanismsCirculatory Shock, types and stages, compensatory mechanisms
Circulatory Shock, types and stages, compensatory mechanisms
 
❤️ Chandigarh Call Girls☎️98151-579OO☎️ Call Girl service in Chandigarh ☎️ Ch...
❤️ Chandigarh Call Girls☎️98151-579OO☎️ Call Girl service in Chandigarh ☎️ Ch...❤️ Chandigarh Call Girls☎️98151-579OO☎️ Call Girl service in Chandigarh ☎️ Ch...
❤️ Chandigarh Call Girls☎️98151-579OO☎️ Call Girl service in Chandigarh ☎️ Ch...
 
Call Girls Bangalore - 450+ Call Girl Cash Payment 💯Call Us 🔝 6378878445 🔝 💃 ...
Call Girls Bangalore - 450+ Call Girl Cash Payment 💯Call Us 🔝 6378878445 🔝 💃 ...Call Girls Bangalore - 450+ Call Girl Cash Payment 💯Call Us 🔝 6378878445 🔝 💃 ...
Call Girls Bangalore - 450+ Call Girl Cash Payment 💯Call Us 🔝 6378878445 🔝 💃 ...
 
👉 Chennai Sexy Aunty’s WhatsApp Number 👉📞 7427069034 👉📞 Just📲 Call Ruhi Colle...
👉 Chennai Sexy Aunty’s WhatsApp Number 👉📞 7427069034 👉📞 Just📲 Call Ruhi Colle...👉 Chennai Sexy Aunty’s WhatsApp Number 👉📞 7427069034 👉📞 Just📲 Call Ruhi Colle...
👉 Chennai Sexy Aunty’s WhatsApp Number 👉📞 7427069034 👉📞 Just📲 Call Ruhi Colle...
 
Chennai ❣️ Call Girl 6378878445 Call Girls in Chennai Escort service book now
Chennai ❣️ Call Girl 6378878445 Call Girls in Chennai Escort service book nowChennai ❣️ Call Girl 6378878445 Call Girls in Chennai Escort service book now
Chennai ❣️ Call Girl 6378878445 Call Girls in Chennai Escort service book now
 
Call girls Service Phullen / 9332606886 Genuine Call girls with real Photos a...
Call girls Service Phullen / 9332606886 Genuine Call girls with real Photos a...Call girls Service Phullen / 9332606886 Genuine Call girls with real Photos a...
Call girls Service Phullen / 9332606886 Genuine Call girls with real Photos a...
 
Lucknow Call Girls Service { 9984666624 } ❤️VVIP ROCKY Call Girl in Lucknow U...
Lucknow Call Girls Service { 9984666624 } ❤️VVIP ROCKY Call Girl in Lucknow U...Lucknow Call Girls Service { 9984666624 } ❤️VVIP ROCKY Call Girl in Lucknow U...
Lucknow Call Girls Service { 9984666624 } ❤️VVIP ROCKY Call Girl in Lucknow U...
 
ANATOMY AND PHYSIOLOGY OF RESPIRATORY SYSTEM.pptx
ANATOMY AND PHYSIOLOGY OF RESPIRATORY SYSTEM.pptxANATOMY AND PHYSIOLOGY OF RESPIRATORY SYSTEM.pptx
ANATOMY AND PHYSIOLOGY OF RESPIRATORY SYSTEM.pptx
 
7 steps How to prevent Thalassemia : Dr Sharda Jain & Vandana Gupta
7 steps How to prevent Thalassemia : Dr Sharda Jain & Vandana Gupta7 steps How to prevent Thalassemia : Dr Sharda Jain & Vandana Gupta
7 steps How to prevent Thalassemia : Dr Sharda Jain & Vandana Gupta
 
Call Girls in Lucknow Just Call 👉👉 8875999948 Top Class Call Girl Service Ava...
Call Girls in Lucknow Just Call 👉👉 8875999948 Top Class Call Girl Service Ava...Call Girls in Lucknow Just Call 👉👉 8875999948 Top Class Call Girl Service Ava...
Call Girls in Lucknow Just Call 👉👉 8875999948 Top Class Call Girl Service Ava...
 
💞 Safe And Secure Call Girls Coimbatore🧿 6378878445 🧿 High Class Coimbatore C...
💞 Safe And Secure Call Girls Coimbatore🧿 6378878445 🧿 High Class Coimbatore C...💞 Safe And Secure Call Girls Coimbatore🧿 6378878445 🧿 High Class Coimbatore C...
💞 Safe And Secure Call Girls Coimbatore🧿 6378878445 🧿 High Class Coimbatore C...
 
(RIYA)🎄Airhostess Call Girl Jaipur Call Now 8445551418 Premium Collection Of ...
(RIYA)🎄Airhostess Call Girl Jaipur Call Now 8445551418 Premium Collection Of ...(RIYA)🎄Airhostess Call Girl Jaipur Call Now 8445551418 Premium Collection Of ...
(RIYA)🎄Airhostess Call Girl Jaipur Call Now 8445551418 Premium Collection Of ...
 
Call Girls in Lucknow Just Call 👉👉8630512678 Top Class Call Girl Service Avai...
Call Girls in Lucknow Just Call 👉👉8630512678 Top Class Call Girl Service Avai...Call Girls in Lucknow Just Call 👉👉8630512678 Top Class Call Girl Service Avai...
Call Girls in Lucknow Just Call 👉👉8630512678 Top Class Call Girl Service Avai...
 
Bhopal❤CALL GIRL 9352988975 ❤CALL GIRLS IN Bhopal ESCORT SERVICE
Bhopal❤CALL GIRL 9352988975 ❤CALL GIRLS IN Bhopal ESCORT SERVICEBhopal❤CALL GIRL 9352988975 ❤CALL GIRLS IN Bhopal ESCORT SERVICE
Bhopal❤CALL GIRL 9352988975 ❤CALL GIRLS IN Bhopal ESCORT SERVICE
 
Chennai Call Girls Service {7857862533 } ❤️VVIP ROCKY Call Girl in Chennai
Chennai Call Girls Service {7857862533 } ❤️VVIP ROCKY Call Girl in ChennaiChennai Call Girls Service {7857862533 } ❤️VVIP ROCKY Call Girl in Chennai
Chennai Call Girls Service {7857862533 } ❤️VVIP ROCKY Call Girl in Chennai
 

Acne

  • 1. ACNE By Anjita Khadka Masters in Clinical Pharmacy 2nd semester
  • 2. ACNE • a skin condition that occurs when your hair follicles become plugged with oil and dead skin cells. • often causes: – whiteheads – blackheads or pimples, and – usually appears on the face, forehead, chest, upper back and shoulders
  • 3. • Also called as acne vulgaris. • most common among teenagers, though it affects people of all ages.
  • 4. PREVALENCE • As high as 95% with a 20 % to 35% prevalence of moderate to severe acne. • Most prevalent in USA, UK, and Australia. • Estimates reveal a 30 % increase in the number of people turning towards homeopathy for the treatment of their Acne vulgaris and other skin problems globally.
  • 5. ACNE SIGNS AND SYMPTOMS • vary depending on the severity of your condition: – Whiteheads (closed plugged pores) – Blackheads (open plugged pores) – Small red, tender bumps (papules) – Pimples (pustules), which are papules with pus at their tips – Large, solid, painful lumps beneath the surface of the skin (nodules) – Painful, pus-filled lumps beneath the surface of the skin (cystic lesions)
  • 6.
  • 7. CAUSES • Excess oil production • Hair follicles clogged by oil and dead skin cells • Bacterial infection (Propionibacterium acnes) • Excess activity of a type of hormone (androgens)
  • 8. RISK FACTORS • Genetic • Obesity: hyperandrogenism • A significant positive family history of acne has been demonstrated especially when acne is found in: – Twins – Mother – First degree relative – Multiple family members
  • 9. AGGRAVATING FACTORS • Smoking • Stress • Facial therapy or, salon facial massage • High glycemic loads diet • Milk and milk products • Tight cloths/ head bands
  • 10.
  • 11.
  • 12. TYPES OF ACNE • Acne conglobata • Occupational acne • Cosmetic acne • Drug-induced acne • Infantile acne • Late onset acne • Acne excoriee • Acne fulminans • Post-facial massage acne
  • 13. Types of acne 1. Acne conglobata:  Severe form  intercommunicating abscesses, cysts and sinuses loaded with serosanguinous fluid or, pus.  Comedines-multiparous  Lesions take months to heal and on healing leave behind deep pitted or, hypertrophic scars, joined by keloidal bridges.  Occlusion syndrome
  • 14. Types of acne 2. Occupational acne: • caused by exposure to industrial chemicals. • Predominantly comedones • Suspected in: -unusal sites of involvement e.g. forearms -unusal age e.g. middle age males
  • 15. Types of acne 3. Cosmetic acne: • Eruption seen in women using cosmetics,especially oil based ones. • Almost always comedones • Lesion frequently on the chin 4. Drug –induced acne: • steroids, androgens, anabolic steroids, OCPs, anti-TB drugs,iodides, bromides and anticonvulsant can cause acneiform eruption. • lesions- monomorphic, consisting of papules and pustules. • Trunk especially back and face may be involved.
  • 16. Types of acne 5. Infantile acne: • due to presence of maternal hormones in the child. • higher in males. • May present at birth and may last for upto 3 yrs. •Lesions similar to those of adloscent acne. 6. Late onset acne: • Acne with onset after 25 years old. •Predominantly as deep seated, persistent lesions on lower half of face. •Exclude underlying androgen secretion pathology, especially polycystic ovarian syndrome.
  • 17. Types of acne 7. Acne excoriee: • seen in young girls, who excessively pick their mild acne. • results in discrete excoriations on the face, while comodones and papules are few and far in between. 8. Acne fulminans: • acute onset • Presents as crusted, ulcerated lesions. • associated with fever, myalgia and arthralgia.
  • 18. Types of acne 9. Post-facial massage acne: • facial massage may be followed (3-6 wks later) by an acneiform eruption in about 30% patient. • indolent deep seated nodules with very few ( or no) comedones. • heal with hyperpigmentation after several weeks. • predominantly on cheeks, along the mandible.
  • 22.
  • 23.
  • 26. PHARMACOLOGICAL TREATMENT • Comedonal acne: – 1st line treatment: Topical retinoid – Usually, initiated with the lowest strength retenoid to minimize redness and dryness. – Strength may be increased if needed. – Alternative therapies: Benzoyl peroxide, azeleic acid or, salicylic acid.
  • 27. • Papular/pustular Acne: – Mild disease: • 1st line therapy: a topical retinoid + topical antibiotic, Benzoyl peroxide may be added. • Alternative therapy: Azaleic acid – Moderate to severe disease: • same 1st line therapy as mild disease. – Severe disease: • 1st line therapy: oral antibiotics+ a topical retinoid + Benzoyl peroxide gel or wash. • Alternative therapy: switching to another type of topical retinoid + another type of antibiotic + Benzoyl peroxide.
  • 28. • Nodular acne: – 1st line therapy: • oral antibiotics + topical retinoid + Benzoyl peroxide – If still persistant, may need a referral to use of oral Isotretinoin therapy.
  • 29.
  • 30.
  • 31. ORAL ANTIBIOTICS • Oral antibiotics and typical doses for Acne: – Doxycycline : 50-100 mg BID – Erythromycin : 250-500mg BID – Minocycline: 50-100mg BID – Tetracycline: 250-500mg BID